NL7106029A - - Google Patents

Info

Publication number
NL7106029A
NL7106029A NL7106029A NL7106029A NL7106029A NL 7106029 A NL7106029 A NL 7106029A NL 7106029 A NL7106029 A NL 7106029A NL 7106029 A NL7106029 A NL 7106029A NL 7106029 A NL7106029 A NL 7106029A
Authority
NL
Netherlands
Application number
NL7106029A
Other versions
NL178594B (nl
NL178594C (nl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of NL7106029A publication Critical patent/NL7106029A/xx
Publication of NL178594B publication Critical patent/NL178594B/xx
Application granted granted Critical
Publication of NL178594C publication Critical patent/NL178594C/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96—Two oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NLAANVRAGE7106029,A 1970-05-21 1971-05-03 Werkwijze ter bereiding van geneesmiddelen met antihypertensieve werking, alsmede werkwijze ter bereiding van 2-(gesubstitueerd amino)4-amino 6,7,8-trimethoxychinazolinen, geschikt voor gebruik bij eerstgenoemde werkwijze. NL178594C (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3954170A 1970-05-21 1970-05-21
US24086572A 1972-04-03 1972-04-03

Publications (3)

Publication Number Publication Date
NL7106029A true NL7106029A (fr) 1971-11-23
NL178594B NL178594B (nl) 1985-11-18
NL178594C NL178594C (nl) 1986-04-16

Family

ID=26716233

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7106029,A NL178594C (nl) 1970-05-21 1971-05-03 Werkwijze ter bereiding van geneesmiddelen met antihypertensieve werking, alsmede werkwijze ter bereiding van 2-(gesubstitueerd amino)4-amino 6,7,8-trimethoxychinazolinen, geschikt voor gebruik bij eerstgenoemde werkwijze.

Country Status (10)

Country Link
US (2) US3669968A (fr)
JP (1) JPS5268191A (fr)
AT (1) AT308120B (fr)
BE (1) BE766444A (fr)
CH (1) CH521353A (fr)
DE (2) DE2120495C2 (fr)
FR (1) FR2092154B1 (fr)
GB (1) GB1309835A (fr)
NL (1) NL178594C (fr)
SE (2) SE384211B (fr)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3980650A (en) * 1972-05-05 1976-09-14 N.V. Koninklijke Pharmaceutische Fabrieken V/H Brocades-Stheeman En Pharmacia 4-Amino-pyrimidine derivatives
GB1383409A (en) * 1972-09-09 1974-02-12 Pfizer Ltd Derivatives of 2-amino- and 4-amino-quinazoline and pharmaceutical compositions containing them
JPS4966691A (fr) * 1972-10-30 1974-06-27
US4026894A (en) * 1975-10-14 1977-05-31 Abbott Laboratories Antihypertensive agents
US4060615A (en) * 1976-02-18 1977-11-29 Mead Johnson & Company 2-Piperazinyl-6,7-dimethoxyquinazolines
SE435380B (sv) 1976-06-15 1984-09-24 Pfizer Forfarande for framstellning av kinazolinforeningar
US4101548A (en) * 1977-02-22 1978-07-18 Bristol-Myers Company 1,2,3-Thiadiazole amides
US4171363A (en) * 1977-02-22 1979-10-16 Bristol-Myers Company 1,2,3-Thiadiazole process
US4102885A (en) * 1977-06-20 1978-07-25 Bristol-Myers Company Process for preparing 2,4-dihaloquinazolines
US4098788A (en) * 1977-06-20 1978-07-04 Bristol-Myers Company Process for preparing quinazolines
US4130647A (en) * 1977-07-08 1978-12-19 Pfizer Inc. Methods for treating congestive heart failure and ischemic heart disease
US4188390A (en) * 1977-11-05 1980-02-12 Pfizer Inc. Antihypertensive 4-amino-2-[4-(1,4-benzodioxan-2-carbonyl) piperazin-1-yl or homopiperazin-1-yl]quinazolines
DK154082C (da) * 1977-11-05 1989-02-27 Pfizer Analogifremgangsmaade til fremstilling af 4-amino-6,7-dimethoxy-2-(piperazin-1-yl eller homopiperazin-1-yl)-quinazolinforbindelser eller farmaceutisk acceptable syreadditionssalte deraf
US4287341A (en) * 1979-11-01 1981-09-01 Pfizer Inc. Alkoxy-substituted-6-chloro-quinazoline-2,4-diones
US4377581A (en) * 1980-03-03 1983-03-22 Pfizer Inc. Chloro- and alkoxy-substituted-2,4-diaminoquinazolines
US4351940A (en) * 1980-03-03 1982-09-28 Pfizer Inc. Chloro- and alkoxy-substituted-2-chloro-4-aminodquinazolines
US4510307A (en) * 1980-08-20 1985-04-09 Asahi Kasei Kogyo Kabushiki Kaisha 6-Quinazolinesulfonyl derivatives and process for preparation thereof
FI70411C (fi) 1980-12-29 1986-09-19 Pfizer Foerfarande foer framstaellning av nya antihypertensiva 4-amino-6,7-dimetoxi-2-piperazinokinazolin derivat
US4704284A (en) * 1982-08-12 1987-11-03 Pfizer Inc. Long-acting matrix tablet formulations
US4582832A (en) * 1984-10-09 1986-04-15 Pfizer Inc. Trimazosin as an anti-atherosclerosis agent
GB8910722D0 (en) * 1989-05-10 1989-06-28 Smithkline Beckman Intercredit Compounds
PT100905A (pt) * 1991-09-30 1994-02-28 Eisai Co Ltd Compostos heterociclicos azotados biciclicos contendo aneis de benzeno, ciclo-hexano ou piridina e de pirimidina, piridina ou imidazol substituidos e composicoes farmaceuticas que os contem
EP0724480B1 (fr) * 1993-10-18 1997-11-19 Imperial Chemical Industries Plc Procede catalytique
CA2422488A1 (fr) * 2000-09-20 2002-03-28 Merck Patent Gesellschaft Mit Beschraenkter Haftung 4-amino-quinazolines
EP1545519B1 (fr) 2002-08-19 2011-03-23 Pfizer Inc. Therapie de combinaison pour maladies hyperproliferatives
WO2004052862A1 (fr) * 2002-12-10 2004-06-24 Ono Pharmaceutical Co., Ltd. Composes heterocycliques contenant de l'azote et leur utilisation medicale
CN1812983A (zh) * 2003-05-30 2006-08-02 兰贝克赛实验室有限公司 取代的吡咯衍生物及其作为hmg－co抑制剂的用途
US20050037063A1 (en) * 2003-07-21 2005-02-17 Bolton Anthony E. Combined therapies
CN101031551A (zh) * 2004-07-06 2007-09-05 安吉永生物制药公司 针对癌症治疗的肝细胞生长因子/c－met活性的喹唑啉调节剂
US20060063803A1 (en) * 2004-09-23 2006-03-23 Pfizer Inc 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds
GT200600381A (es) 2005-08-25 2007-03-28 Compuestos organicos
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
SG166829A1 (en) * 2005-11-08 2010-12-29 Ranbaxy Lab Ltd Process for (3r, 5r)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
WO2007081978A2 (fr) * 2006-01-11 2007-07-19 Angion Biomedica Corporation Modulateurs de l'activite facteur de croissance des hepatocytes / c-met
US7919506B2 (en) 2006-03-10 2011-04-05 Pfizer Inc. Dibenzyl amine compounds and derivatives
WO2008020314A2 (fr) * 2006-03-14 2008-02-21 Ranbaxy Laboratories Limited Formulations de dosage stabilisantes à base de statine
WO2008010087A2 (fr) * 2006-07-14 2008-01-24 Ranbaxy Laboratories Limited FORMES POLYMORPHES D'UN INHIBITEUR DE LA HMG-CoA-RÉDUCTASE ET LEURS UTILISATIONS
JP5498168B2 (ja) 2006-12-01 2014-05-21 ブリストル−マイヤーズ スクイブ カンパニー アテローム性動脈硬化および循環器疾患の治療のためのｃｅｔｐ阻害剤としてのｎ−（（３−ベンジル）−２，２−（ビス−フェニル）−プロパン−１−アミン誘導体
SG11201507496UA (en) 2013-04-17 2015-11-27 Pfizer N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
WO2016055901A1 (fr) 2014-10-08 2016-04-14 Pfizer Inc. Composés d'amide substitué
US11248001B2 (en) 2019-01-18 2022-02-15 Astrazeneca Ab PCSK9 inhibitors and methods of use thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1156973A (en) * 1965-07-06 1969-07-02 Quinazoline Derivatives

Also Published As

Publication number Publication date
BE766444A (fr) 1971-10-29
GB1309835A (en) 1973-03-14
JPS5268191A (en) 1977-06-06
US3769286A (en) 1973-10-30
DE2120495A1 (de) 1971-12-02
NL178594B (nl) 1985-11-18
SE400280B (sv) 1978-03-20
CH521353A (fr) 1972-04-15
NL178594C (nl) 1986-04-16
AT308120B (de) 1973-06-25
JPS5439386B2 (fr) 1979-11-27
SE384211B (sv) 1976-04-26
DE2167157C2 (de) 1982-06-09
US3669968A (en) 1972-06-13
DE2120495C2 (de) 1982-06-03
FR2092154A1 (fr) 1972-01-21
FR2092154B1 (fr) 1975-01-17

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Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
V4 Discontinued because of reaching the maximum lifetime of a patent