NL7601809A - 2-Oxo-1-pyrrolidineactohydrazide cpds - prepd. by reacting alkyl 2-oxo-1-pyrrolidineacetates with hydrazine cpds - Google Patents
2-Oxo-1-pyrrolidineactohydrazide cpds - prepd. by reacting alkyl 2-oxo-1-pyrrolidineacetates with hydrazine cpdsInfo
- Publication number
- NL7601809A NL7601809A NL7601809A NL7601809A NL7601809A NL 7601809 A NL7601809 A NL 7601809A NL 7601809 A NL7601809 A NL 7601809A NL 7601809 A NL7601809 A NL 7601809A NL 7601809 A NL7601809 A NL 7601809A
- Authority
- NL
- Netherlands
- Prior art keywords
- oxo
- cpds
- pyrrolidineactohydrazide
- pyrrolidineacetates
- prepd
- Prior art date
Links
- -1 alkyl 2-oxo-1-pyrrolidineacetates Chemical class 0.000 title abstract 2
- OAKJQQAXSVQMHS-UHFFFAOYSA-N Hydrazine Chemical compound NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 title 2
- JCCPDFVXLPOKHI-UHFFFAOYSA-N 2-(2-oxopyrrolidin-1-yl)acetohydrazide Chemical compound NNC(=O)CN1CCCC1=O JCCPDFVXLPOKHI-UHFFFAOYSA-N 0.000 abstract 1
- LBTUTDYXOOUODJ-UHFFFAOYSA-N 2-pyrrolidin-1-ylacetamide Chemical compound NC(=O)CN1CCCC1 LBTUTDYXOOUODJ-UHFFFAOYSA-N 0.000 abstract 1
- GMZVRMREEHBGGF-UHFFFAOYSA-N Piracetam Chemical compound NC(=O)CN1CCCC1=O GMZVRMREEHBGGF-UHFFFAOYSA-N 0.000 abstract 1
- 208000037175 Travel-Related Illness Diseases 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 201000003152 motion sickness Diseases 0.000 abstract 1
- 229960004526 piracetam Drugs 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
- C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
2-Oxo-1-pyrrolidineacetohydrazide cpds. of formula (I) (where R1 is H or 2-oxo-1-pyrrolidineacetyl) are new cpds. obtainable by reacting an ester of formula (II) (where R2 is 1-4C alkyl) with R1-NH-NH2 (III). (I) are useful as inters. for 2-oxo. 1-pyrrolidineacetamide (piracetam), a known agent against travel sickness, for the treatment of senile involution and for promoting learning capacity. (I) are themselves also pharmacologically active (e.g. as psychopharmaceuticals).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL7601809A NL7601809A (en) | 1976-02-23 | 1976-02-23 | 2-Oxo-1-pyrrolidineactohydrazide cpds - prepd. by reacting alkyl 2-oxo-1-pyrrolidineacetates with hydrazine cpds |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL7601809A NL7601809A (en) | 1976-02-23 | 1976-02-23 | 2-Oxo-1-pyrrolidineactohydrazide cpds - prepd. by reacting alkyl 2-oxo-1-pyrrolidineacetates with hydrazine cpds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL7601809A true NL7601809A (en) | 1977-08-25 |
Family
ID=19825666
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL7601809A NL7601809A (en) | 1976-02-23 | 1976-02-23 | 2-Oxo-1-pyrrolidineactohydrazide cpds - prepd. by reacting alkyl 2-oxo-1-pyrrolidineacetates with hydrazine cpds |
Country Status (1)
| Country | Link |
|---|---|
| NL (1) | NL7601809A (en) |
-
1976
- 1976-02-23 NL NL7601809A patent/NL7601809A/en not_active Application Discontinuation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BA | A request for search or an international-type search has been filed | ||
| BB | A search report has been drawn up | ||
| BV | The patent application has lapsed |