NL7610480A - Werkwijze ter bereiding van hypolipemische ver- bindingen alsmede farmaceutische preparaten die deze verbindingen als actieve component bevatten. - Google Patents

Werkwijze ter bereiding van hypolipemische ver- bindingen alsmede farmaceutische preparaten die deze verbindingen als actieve component bevatten.

Info

Publication number
NL7610480A
NL7610480A NL7610480A NL7610480A NL7610480A NL 7610480 A NL7610480 A NL 7610480A NL 7610480 A NL7610480 A NL 7610480A NL 7610480 A NL7610480 A NL 7610480A NL 7610480 A NL7610480 A NL 7610480A
Authority
NL
Netherlands
Prior art keywords
compounds
preparation
active component
pharmaceutical preparations
hypolipemic
Prior art date
Application number
NL7610480A
Other languages
English (en)
Dutch (nl)
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of NL7610480A publication Critical patent/NL7610480A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/16—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by esterified hydroxyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/005—Compounds containing elements of Groups 1 or 11 of the Periodic Table without C-Metal linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Steroid Compounds (AREA)
NL7610480A 1975-09-25 1976-09-21 Werkwijze ter bereiding van hypolipemische ver- bindingen alsmede farmaceutische preparaten die deze verbindingen als actieve component bevatten. NL7610480A (nl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US61680675A 1975-09-25 1975-09-25

Publications (1)

Publication Number Publication Date
NL7610480A true NL7610480A (nl) 1977-03-29

Family

ID=24471018

Family Applications (1)

Application Number Title Priority Date Filing Date
NL7610480A NL7610480A (nl) 1975-09-25 1976-09-21 Werkwijze ter bereiding van hypolipemische ver- bindingen alsmede farmaceutische preparaten die deze verbindingen als actieve component bevatten.

Country Status (22)

Country Link
US (1) US4125729A (fr)
JP (1) JPS5239647A (fr)
AR (1) AR212921A1 (fr)
AT (1) AT348992B (fr)
AU (1) AU1752576A (fr)
BE (1) BE846569A (fr)
DD (1) DD129056A5 (fr)
DE (1) DE2642164A1 (fr)
DK (1) DK431176A (fr)
ES (1) ES451822A1 (fr)
FI (1) FI762701A7 (fr)
FR (1) FR2325368A1 (fr)
GB (1) GB1554299A (fr)
HU (1) HU173950B (fr)
LU (1) LU75858A1 (fr)
NL (1) NL7610480A (fr)
NO (1) NO763273L (fr)
NZ (1) NZ181868A (fr)
PT (1) PT65601B (fr)
RO (1) RO70552A (fr)
SE (1) SE7610630L (fr)
ZA (1) ZA765075B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0206772A3 (fr) * 1985-06-20 1988-05-11 E.I. Du Pont De Nemours And Company Dérivés d'acide aryloxybenzèneacétique herbicides
US5284971A (en) * 1992-07-16 1994-02-08 Syntex (U.S.A.) Inc. 4-(3-cyclohexyl-4-hydroxy or-methoxy phenylsulfonyl) 3,5 dibromo phenyl acetic thyromimetic cholesterol-lowering agents
CN1082099C (zh) * 1999-05-08 2002-04-03 吉林大学 纳米引晶法选择性生长金刚石膜的工艺
WO2002009651A2 (fr) * 2000-08-02 2002-02-07 Smithkline Beecham Corporation Inhibiteurs de synthase d'acide gras
EP1366012A4 (fr) * 2001-02-09 2005-11-02 Merck & Co Inc Acides 2-aryloxy-2-arylalcano ques utilis s pour le traitement du diab tes et des troubles lipidiques
US7399775B2 (en) 2001-12-27 2008-07-15 Daiichi Pharmaceutical Co., Ltd. β-amyloid protein production/secretion inhibitor
PL379466A1 (pl) 2003-06-30 2006-09-18 Daiichi Sankyo Company , Limited Heterocykliczne pochodne metylosulfonu
CA2555814A1 (fr) * 2004-02-18 2005-09-01 Metabolex, Inc. Utilisation d'acides phenylacetiques substitues par alpha-(aryloxy, arylamino, arylthio ou arylmethyle substitue par trifluoromethyle)-trifluoromethyle et de leurs derives en tantqu'agents antidiabetiques
WO2005115384A2 (fr) * 2004-05-25 2005-12-08 Metabolex, Inc. Triazoles substitués bicyliques comme modulateurs de ppar et méthodes de préparation
RU2006145872A (ru) * 2004-05-25 2008-06-27 Метаболекс, Инк. (Us) Замещенные триазолы в качестве модуляторов ppar и способы их получения
GB0510585D0 (en) * 2005-05-24 2005-06-29 Novartis Ag Organic compounds
EP3044216B1 (fr) * 2013-08-20 2022-02-23 University of Washington through its Center for Commercialization Nouveaux inhibiteurs spécifiques de l'hydroxylase d'acide rétinoïque cytochrome p450 26

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3378582A (en) * 1964-03-20 1968-04-16 Merck & Co Inc (alpha-phenoxy)-and (alpha-phenylthio)-omegaphenyl-alkanoic acids
US3517051A (en) * 1964-03-20 1970-06-23 Merck & Co Inc Phenoxy substituted phenylacetic acids
US3707549A (en) * 1967-12-05 1972-12-26 Lilly Co Eli Alpha-substituted hydrocinnamic acids and derivatives thereof
US3600437A (en) * 1969-05-28 1971-08-17 Lilly Co Eli Substituted phenylalkanoic acids and derivatives thereof

Also Published As

Publication number Publication date
FR2325368A1 (fr) 1977-04-22
AR212921A1 (es) 1978-11-15
NZ181868A (en) 1979-06-08
NO763273L (no) 1977-03-28
HU173950B (hu) 1979-09-28
LU75858A1 (fr) 1977-05-04
DE2642164A1 (de) 1977-04-07
ATA705376A (de) 1978-08-15
DK431176A (da) 1977-03-26
DD129056A5 (de) 1977-12-28
PT65601A (en) 1976-10-01
BE846569A (fr) 1977-03-24
GB1554299A (en) 1979-10-17
PT65601B (en) 1978-03-28
AT348992B (de) 1979-03-12
US4125729A (en) 1978-11-14
AU1752576A (en) 1978-03-16
RO70552A (fr) 1981-09-24
ES451822A1 (es) 1977-12-16
FI762701A7 (fr) 1977-03-26
SE7610630L (sv) 1977-03-26
ZA765075B (en) 1977-08-31
JPS5239647A (en) 1977-03-28

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