NO130728B - - Google Patents

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Publication number
NO130728B
NO130728B NO00802/71A NO80271A NO130728B NO 130728 B NO130728 B NO 130728B NO 00802/71 A NO00802/71 A NO 00802/71A NO 80271 A NO80271 A NO 80271A NO 130728 B NO130728 B NO 130728B
Authority
NO
Norway
Prior art keywords
bolt
string
bore
hole
wire
Prior art date
Application number
NO00802/71A
Other languages
English (en)
Norwegian (no)
Other versions
NO130728C (de
Inventor
T Schwan
S Burrous
J Butterfield
Original Assignee
Norwich Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norwich Pharma Co filed Critical Norwich Pharma Co
Publication of NO130728B publication Critical patent/NO130728B/no
Publication of NO130728C publication Critical patent/NO130728C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D239/08—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms directly attached in position 2
    • C07D239/10—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom
    • C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Joining Of Building Structures In Genera (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Indole Compounds (AREA)
NO802/71A 1970-03-05 1971-03-03 NO130728C (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1698270A 1970-03-05 1970-03-05

Publications (2)

Publication Number Publication Date
NO130728B true NO130728B (de) 1974-10-21
NO130728C NO130728C (de) 1975-01-29

Family

ID=21780073

Family Applications (1)

Application Number Title Priority Date Filing Date
NO802/71A NO130728C (de) 1970-03-05 1971-03-03

Country Status (14)

Country Link
US (1) US3681349A (de)
AT (1) AT305288B (de)
BE (1) BE763745A (de)
CH (1) CH555343A (de)
DE (1) DE2110445C3 (de)
DK (1) DK127427B (de)
ES (1) ES388780A1 (de)
FR (1) FR2085673B1 (de)
GB (1) GB1294626A (de)
IL (1) IL36189A0 (de)
NL (1) NL7102519A (de)
NO (1) NO130728C (de)
SE (1) SE376420B (de)
ZA (1) ZA71928B (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL39003A (en) * 1971-03-25 1975-02-10 Morton Norwich Products Inc 1-(substituted benzyl)tetrahydro-2-(1h)-pyrimidones and their preparation
US3957785A (en) * 1971-12-02 1976-05-18 Societa' Farmaceutici Italia S.P.A. Bβ-Pyrimidino-aminomethyl-10α-ergoline and 10α-methoxyergoline derivatives
US3956325A (en) * 1974-01-21 1976-05-11 Smithkline Corporation 5-Heterocyclic-1,2,3,6-tetrahydro-4(5H) pyrimidinone
US4003900A (en) * 1976-03-11 1977-01-18 Morton-Norwich Products, Inc. 1-Benzyl-5-chloro-2-(1H)-pyrimidone
US4002627A (en) * 1976-03-26 1977-01-11 Morton-Norwich Products, Inc. 1-Benzyl-3-methyl-3,4,5,6-tetrahydro-2(1H) pyrimidone
US4052399A (en) * 1976-09-13 1977-10-04 Morton-Norwich Products, Inc. 1-[2-(Hexahydro-1H-azepino)ethyl]-2(1H)pyrimidone dihydrochloride
US4052400A (en) * 1976-10-29 1977-10-04 Morton-Norwich Products, Inc. Hypertensive 1-substituted 2(1h)-pyrimidones
EP2125750B1 (de) * 2007-02-26 2014-05-21 Vitae Pharmaceuticals, Inc. Zyklische harnstoff- und carbamat-hemmer aus 11-beta-hydroxysteroid-dehydrogenase 1
US8329897B2 (en) * 2007-07-26 2012-12-11 Vitae Pharmaceuticals, Inc. Synthesis of inhibitors of 11β-hydroxysteroid dehydrogenase type 1
AR069207A1 (es) * 2007-11-07 2010-01-06 Vitae Pharmaceuticals Inc Ureas ciclicas como inhibidores de la 11 beta - hidroxi-esteroide deshidrogenasa 1
JP5490014B2 (ja) 2007-12-11 2014-05-14 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１型の環状尿素阻害剤
TW200934490A (en) * 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
EP2252601B1 (de) 2008-01-24 2012-12-19 Vitae Pharmaceuticals, Inc. Cyclische carbazate und semicarbazide als inhibitoren von 11beta-hydroxysteroiddehydrogenase 1
CA2714532A1 (en) * 2008-02-11 2009-08-20 Vitae Pharmaceuticals, Inc. 1,3-oxazepan-2-one and 1,3-diazepan-2-one inhibitors of 11.beta.-hydroxysteroid dehydrogenase 1
EP2254872A2 (de) * 2008-02-15 2010-12-01 Vitae Pharmaceuticals, Inc. Cycloalkyllactamderivate als inhibitoren von 11-beta-hydroxysteroiddehydrogenase 1
EP2274287B1 (de) * 2008-03-18 2016-03-09 Vitae Pharmaceuticals, Inc. Inhibitoren der 11beta-hydroxysteroiddehydrogenase vom typ 1
JP5538365B2 (ja) * 2008-05-01 2014-07-02 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状阻害剤
EP2291373B1 (de) * 2008-05-01 2013-09-11 Vitae Pharmaceuticals, Inc. Cyclische inhibitoren von 11beta-hydroxysteroiddehydrogenase 1
CA2722427A1 (en) * 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CL2009001058A1 (es) * 2008-05-01 2010-09-10 Vitae Pharmaceuticals Inc Compuestos derivados de oxazinas sustituidas, inhibidores de la 11b-hidroxiesteroide deshidrogenasa de tipo-1; composicion farmaceutica; y uso del compuesto para inhibir la actividad de 11b-hsd1, como en el tratamiento de la diabetes, dislipidemia, hipertension, obesidad, cancer, glaucoma, entre otras.
JP5777030B2 (ja) 2008-07-25 2015-09-09 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング １１β−ヒドロキシステロイドデヒドロゲナーゼ１の阻害剤
WO2010010150A1 (en) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh Synthesis of inhibitors of 11beta-hydroxysteroid dehydrogenase type 1
RU2539979C2 (ru) * 2008-07-25 2015-01-27 Вайтаи Фармасьютиклз, Инк. Циклические ингибиторы 11бета-гидроксистероид-дегидрогеназы 1
WO2010089303A1 (en) 2009-02-04 2010-08-12 Boehringer Ingelheim International Gmbh CYCLIC INHIBITORS OF 11 β-HYDROXYSTEROID DEHYDROGENASE 1
TW201039034A (en) * 2009-04-27 2010-11-01 Chunghwa Picture Tubes Ltd Pixel structure and the method of forming the same
MA33216B1 (fr) 2009-04-30 2012-04-02 Boehringer Ingelheim Int Inhibiteurs cycliques de la 11béta-hydroxysteroïde déshydrogénase 1
US20100331320A1 (en) * 2009-04-30 2010-12-30 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2440537A1 (de) 2009-06-11 2012-04-18 Vitae Pharmaceuticals, Inc. Cyclische hemmer der 11beta-hydroxysteroiddehydrogenase 1 auf basis der 1,3 -oxazinan- 2 -on-struktur
WO2011002910A1 (en) 2009-07-01 2011-01-06 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
JP5750449B2 (ja) 2009-11-05 2015-07-22 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規キラルリンリガンド
TWI531571B (zh) * 2009-11-06 2016-05-01 維它藥物公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜芳基羰基衍生物
EP2576570A1 (de) 2010-05-26 2013-04-10 Boehringer Ingelheim International GmbH 2-oxo-1,2-dihydropyridin-4-ylborsäure-derivate
EP2582698B1 (de) 2010-06-16 2016-09-14 Vitae Pharmaceuticals, Inc. Substituierte 5-,6- und 7-gliedrige heterocyclen, medikamente mit derartigen verbindungen und ihre verwendung
JP5813106B2 (ja) 2010-06-25 2015-11-17 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 代謝障害の処置のための１１−β−ＨＳＤ１のインヒビターとしてのアザスピロヘキサノン
BR112013010021A2 (pt) 2010-11-02 2019-09-24 Boehringer Ingelheim Int combinações farmacêuticas para o tratamento de distúrbios metabólicos.
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE562987A (de) * 1956-12-05
DE1121617B (de) * 1959-05-26 1962-01-11 Huels Chemische Werke Ag Verfahren zur Herstellung von Tetrahydropyrimidin-2-onderivaten
DE1545601A1 (de) * 1965-07-22 1969-08-07 Basf Ag Verfahren zur Herstellung von Hexahydro-pyrimidinderivaten
DE1670368A1 (de) * 1966-07-16 1970-11-05 Cassella Farbwerke Mainkur Ag Verfahren zur Herstellung aralkylsubstituierter Lactame und Cyclischer Harnstoffe
DE1670241A1 (de) * 1967-07-01 1971-01-28 Basf Ag Verfahren zur Herstellung von 2-Oxohexahydropyrimidinen

Also Published As

Publication number Publication date
AT305288B (de) 1973-02-26
FR2085673B1 (de) 1974-09-06
IL36189A0 (en) 1971-04-28
DK127427B (da) 1973-11-05
NO130728C (de) 1975-01-29
NL7102519A (de) 1971-09-07
ES388780A1 (es) 1975-03-01
ZA71928B (en) 1972-09-27
DE2110445C3 (de) 1975-05-28
US3681349A (en) 1972-08-01
SE376420B (de) 1975-05-26
CH555343A (de) 1974-10-31
DE2110445A1 (de) 1971-11-04
BE763745A (fr) 1971-09-03
GB1294626A (en) 1972-11-01
DE2110445B2 (de) 1974-10-10
FR2085673A1 (de) 1971-12-31

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