NO138061C - Analogifremgangsmaate for fremstilling av nye terapeutisk aktive substituerte difenylpropionsyrederivater - Google Patents

Analogifremgangsmaate for fremstilling av nye terapeutisk aktive substituerte difenylpropionsyrederivater

Info

Publication number
NO138061C
NO138061C NO2479/73A NO247973A NO138061C NO 138061 C NO138061 C NO 138061C NO 2479/73 A NO2479/73 A NO 2479/73A NO 247973 A NO247973 A NO 247973A NO 138061 C NO138061 C NO 138061C
Authority
NO
Norway
Prior art keywords
difenylpropion
acid derivatives
therapeutically active
preparing new
active substituted
Prior art date
Application number
NO2479/73A
Other languages
English (en)
Norwegian (no)
Other versions
NO138061B (no
Inventor
Stewart Sanders Adams
Bernard John Armitage
John Stuart Nicholson
Original Assignee
Boots Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boots Co Ltd filed Critical Boots Co Ltd
Publication of NO138061B publication Critical patent/NO138061B/no
Publication of NO138061C publication Critical patent/NO138061C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/10—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D263/14—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/001—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by modification in a side chain
    • C07C37/002—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by modification in a side chain by transformation of a functional group, e.g. oxo, carboxyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/24—Halogenated derivatives
    • C07C39/367—Halogenated derivatives polycyclic non-condensed, containing only six-membered aromatic rings as cyclic parts, e.g. halogenated poly-hydroxyphenylalkanes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/64—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/277—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
    • C07C49/83—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/52—Unsaturated compounds containing hydroxy or O-metal groups a hydroxy or O-metal group being bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/56—Unsaturated compounds containing hydroxy or O-metal groups containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO2479/73A 1972-06-15 1973-06-14 Analogifremgangsmaate for fremstilling av nye terapeutisk aktive substituerte difenylpropionsyrederivater NO138061C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2810472A GB1396726A (en) 1972-06-15 1972-06-15 Phenylalkanoic acids

Publications (2)

Publication Number Publication Date
NO138061B NO138061B (no) 1978-03-13
NO138061C true NO138061C (no) 1978-06-21

Family

ID=10270338

Family Applications (1)

Application Number Title Priority Date Filing Date
NO2479/73A NO138061C (no) 1972-06-15 1973-06-14 Analogifremgangsmaate for fremstilling av nye terapeutisk aktive substituerte difenylpropionsyrederivater

Country Status (26)

Country Link
US (1) US3969402A (fr)
JP (1) JPS4961144A (fr)
AR (1) AR211760A1 (fr)
AT (1) AT329036B (fr)
BE (1) BE800951A (fr)
CA (1) CA1012151A (fr)
CH (1) CH584180A5 (fr)
CS (1) CS176239B2 (fr)
DD (1) DD108977A5 (fr)
DE (1) DE2329125A1 (fr)
ES (1) ES415919A1 (fr)
FI (1) FI57929C (fr)
FR (1) FR2189036B1 (fr)
GB (1) GB1396726A (fr)
HU (1) HU167229B (fr)
IE (1) IE38031B1 (fr)
IL (1) IL42447A (fr)
LU (1) LU67781A1 (fr)
NL (1) NL7308349A (fr)
NO (1) NO138061C (fr)
PL (1) PL102580B1 (fr)
RO (1) RO62810A (fr)
SE (1) SE409855B (fr)
SU (1) SU578854A3 (fr)
YU (1) YU155673A (fr)
ZA (1) ZA734053B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4205176A (en) * 1978-10-18 1980-05-27 Cincinnati Milacron Chemicals Inc. Ester substituted oxazolines
US4247466A (en) * 1979-07-05 1981-01-27 American Cyanamid Company Lactone metabolites of 3-(4-biphenylylcarbonyl)propionic acid
JPS5735543A (en) * 1980-08-13 1982-02-26 Hisamitsu Pharmaceut Co Inc Novel phenylacetic acid derivative
JPS5762239A (en) * 1980-08-26 1982-04-15 Hisamitsu Pharmaceut Co Inc Novel phenylacetic acid derivative
DE3049405A1 (de) * 1980-12-23 1982-07-15 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue derivate von antiphlogistisch wirksamen carbonsaeuren, ihre herstellung und medizinische anwendung
US4792560A (en) * 1985-04-03 1988-12-20 Rorer Pharmaceutical Corporation Quinoline hydroxamates and their use as modulators of arachidonic acid metabolic pathways
US5071988A (en) * 1989-10-27 1991-12-10 American Home Products Corporation Substituted benzoylbenzene-, biphenyl- and 2-oxazole-alkanoic acid derivatives
US5218124A (en) * 1989-10-27 1993-06-08 American Home Products Corporation Substituted benzoylbenzene-, biphenyl- and 2-oxazole-alkanoic acid derivatives as inhibitors of pla2 and lipoxygenase
PH30449A (en) * 1991-11-25 1997-05-28 Lilly Co Eli Substituted phenyl phenol leukotriene antagonists
CZ104797A3 (en) * 1994-10-06 1997-07-16 Bayer Ag Substituted biphenyloxazolines, process of their preparation, intermediates for their preparation, preparations in which said substances are comprised and their application
FR2744445B1 (fr) 1996-02-01 1998-10-02 Roussel Uclaf Composes biphenyles nouveaux et/ou a titre de medicament, compositions pharmaceutiques les contenant, leur procede de preparation et les intermediaires de ce procede
FR2880885B1 (fr) * 2005-01-14 2009-01-30 Merck Sante Soc Par Actions Si Derives d'acide phenylbenzoique, procedes pour leur preparation, compositions pharmaceutiques les contenant et applications en therapeutique
WO2007096647A2 (fr) * 2006-02-27 2007-08-30 Sterix Limited Composé

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1091403A (en) * 1964-01-24 1967-11-15 Boots Pure Drug Co Ltd Therapeutically active phenylalkane derivatives
US3624142A (en) * 1964-09-10 1971-11-30 Merck & Co Inc Substituted biphenyl acetic acid derivatives
US3671580A (en) * 1969-12-22 1972-06-20 Merck & Co Inc Substituted biphenyl acetic acids and ester derivatives thereof

Also Published As

Publication number Publication date
LU67781A1 (fr) 1973-08-16
SE409855B (sv) 1979-09-10
DE2329125A1 (de) 1974-01-03
DD108977A5 (fr) 1974-10-12
FI57929B (fi) 1980-07-31
NO138061B (no) 1978-03-13
IE38031B1 (en) 1977-12-07
IE38031L (en) 1973-12-15
ATA522873A (de) 1975-07-15
AR211760A1 (es) 1978-03-15
YU155673A (en) 1981-04-30
US3969402A (en) 1976-07-13
FR2189036A1 (fr) 1974-01-25
BE800951A (fr) 1973-12-17
CH584180A5 (fr) 1977-01-31
HU167229B (fr) 1975-09-27
PL102580B1 (pl) 1979-04-30
FR2189036B1 (fr) 1980-04-11
IL42447A (en) 1977-05-31
SU578854A3 (ru) 1977-10-30
CS176239B2 (fr) 1977-06-30
CA1012151A (en) 1977-06-14
ZA734053B (en) 1974-05-29
RO62810A (fr) 1978-01-15
IL42447A0 (en) 1973-08-29
GB1396726A (en) 1975-06-04
FI57929C (fi) 1980-11-10
AU5700173A (en) 1974-12-19
NL7308349A (fr) 1973-12-18
AT329036B (de) 1976-04-26
JPS4961144A (fr) 1974-06-13
ES415919A1 (es) 1976-05-16

Similar Documents

Publication Publication Date Title
NO140589C (no) Analogifremgangsmaate for fremstilling av nye, terapeutisk aktive 3,4-dihydrokarbostyrilderivater
SE406762B (sv) Forfarande for framstellning av prostansyraderivat
NO137782C (no) Analogifremgangsmaate for fremstilling av nye farmakologisk aktive amino-fenyl-etanolaminer
NO142033C (no) Analogifremgangsmaate for fremstilling av nye terapeutisk aktive isopropylamino-3-fenoksypropanoler
NO138336C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive benzofuranderivater
NO139167C (no) Analogifremgangsmaate for fremstilling av nye terapeutisk aktive aminer
NO138599C (no) Analogifremgangsmaate til fremstilling av nye, terapeutisk virksomme tienopyrimidinderivater
SE385698B (sv) Forfarande for framstellning av kinolinettiksyraderivat
NO138999C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive difenylyl-alkanoylaminopyridiner
NO141651C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive aroyl-substituerte fenyleddiksyrederivater
NO140348C (no) Analogifremgangsmaate til fremstilling av nye terapeutisk aktive 3-(amino-2-hydroksypropoksy)-isoindolin-1-on-forbindelser
NO140012C (no) Analogifremgangsmaate for fremstilling av nye terapeutisk aktive derivater av naftyridin
NO137858C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive indanoner
SE399708B (sv) Forfarande for framstellning av tioxanton-2-karboxylsyraderivat
NO138063C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive normorfinon-derivater
SE416729B (sv) Forfarande for framstellning av salter av p-dihydroxibensendisulfonsyra
NO137728C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrasi-4-oksyd-derivater
NO740411L (no) Analogifremgangsmåte for fremstilling av nye terapeutisk aktive derivater av isoindolin-1-on.
SE394810B (sv) Analogiforfarande for framstellning av nya terapeutiskt aktiva derivat av dipeptider
SE402111B (sv) Analogiforfarande for framstellning av pregnansyraderivat
NO136840C (no) Analogifremgangsm}te til fremstilling av nye, terapeutisk aktive derivater av isoindolin
NO138806C (no) Analogifremgangsmaate for fremstilling av neuroleptisk aktive 6-fluor-substituert tiaxanten-derivater
NO140421C (no) Analogifremgangsmaate for fremstilling av nye anti-inflammatorisk virksomme acylaminosyreestere
NO140825C (no) Analogifremgangmaate ved fremstilling av terapeutisk aktive pregnan-21-syrederivater
NO138850C (no) Analogifremgangsmaater for fremstilling av nye terapeutisk aktive derivater av ditiino(1,4)(2,3-c)pyrrol