NO151319C - Analogifremgangsmaate for fremstilling av terapeutisk aktive beta-mono-fluormetyl-beta-alanin- og beta-difluormetyl-beta-alanin-forbindelser - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive beta-mono-fluormetyl-beta-alanin- og beta-difluormetyl-beta-alanin-forbindelser

Info

Publication number
NO151319C
NO151319C NO802218A NO802218A NO151319C NO 151319 C NO151319 C NO 151319C NO 802218 A NO802218 A NO 802218A NO 802218 A NO802218 A NO 802218A NO 151319 C NO151319 C NO 151319C
Authority
NO
Norway
Prior art keywords
beta
alanine
fluormethyl
difluormethyl
mono
Prior art date
Application number
NO802218A
Other languages
English (en)
Norwegian (no)
Other versions
NO151319B (no
NO802218L (no
Inventor
Philippe Bey
Michael Jung
Fritz Gerhart
Original Assignee
Merrell Toraude & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Toraude & Co filed Critical Merrell Toraude & Co
Publication of NO802218L publication Critical patent/NO802218L/no
Publication of NO151319B publication Critical patent/NO151319B/no
Publication of NO151319C publication Critical patent/NO151319C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/20Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04Formation of amino groups in compounds containing carboxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO802218A 1979-07-26 1980-07-23 Analogifremgangsmaate for fremstilling av terapeutisk aktive beta-mono-fluormetyl-beta-alanin- og beta-difluormetyl-beta-alanin-forbindelser NO151319C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7926030 1979-07-26
GB8002553 1980-01-25

Publications (3)

Publication Number Publication Date
NO802218L NO802218L (no) 1981-01-27
NO151319B NO151319B (no) 1984-12-10
NO151319C true NO151319C (no) 1985-03-20

Family

ID=26272327

Family Applications (1)

Application Number Title Priority Date Filing Date
NO802218A NO151319C (no) 1979-07-26 1980-07-23 Analogifremgangsmaate for fremstilling av terapeutisk aktive beta-mono-fluormetyl-beta-alanin- og beta-difluormetyl-beta-alanin-forbindelser

Country Status (10)

Country Link
US (1) US4375477A (da)
EP (1) EP0024965B1 (da)
AU (1) AU536371B2 (da)
CA (1) CA1161450A (da)
DE (1) DE3062893D1 (da)
DK (1) DK149269C (da)
ES (1) ES8105969A1 (da)
NO (1) NO151319C (da)
NZ (1) NZ194348A (da)
PH (1) PH16349A (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ194347A (en) * 1979-07-26 1982-11-23 Merrell Toraude & Co Fluorinated alkenylamines intermediate alkenyl fluorinated methyl ketimine magnesium halides and preparation of certain amino alkanoic acids
GB2083030B (en) * 1980-08-23 1984-03-07 Merrell Toraude & Co Fluorinated pentene diamine derivatives
GB2082578B (en) * 1980-08-23 1984-05-23 Merrell Toraude & Co Fluorinated amino-butyric acid and diaminobutane derivatives
US4518528A (en) * 1983-05-19 1985-05-21 Rasnick David W α Amino fluoro ketones
EP0353732A3 (de) * 1988-08-05 1991-11-06 Ciba-Geigy Ag Neue Fluorolefine, Verfahren zu deren Herstellung und deren Verwendung
IL126999A (en) 1996-07-24 2002-03-10 Warner Lambert Co Pharmaceutical preparations containing isobutylgaba and its history for use in the treatment of pain
US6306909B1 (en) 1997-03-12 2001-10-23 Queen's University At Kingston Anti-epileptogenic agents
US6541520B1 (en) * 1998-08-05 2003-04-01 Brookhaven Science Associates Treatment of addiction and addiction-related behavior
CA2440834A1 (en) * 2001-03-13 2002-09-19 Queen's University At Kingston Anti-epileptogenic agents
US20030032579A1 (en) * 2001-04-20 2003-02-13 Pfizer Inc. Therapeutic use of selective PDE10 inhibitors
CA2448160A1 (en) * 2001-05-25 2002-12-05 Queen's University At Kingston Heterocyclic beta-amino acids and their use as anti-epileptogenic agents
WO2003102015A2 (en) * 2002-05-29 2003-12-11 University Of Florida Method and apparatus for detecting and monitoring peptides, and peptides identified therewith
CA2903000C (en) 2013-01-28 2021-10-12 Hector L. Lopez Methods of improving tolerability, pharmacodynamics, and efficacy of .beta.-alanine and use therefor

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2662915A (en) * 1952-06-30 1953-12-15 Du Pont Alpha-amino acids containing alpha, fluorinated-alkyl or cycloalkyl groups
JPS5225458Y2 (da) * 1971-05-17 1977-06-10
US3972921A (en) * 1974-11-08 1976-08-03 Merck & Co., Inc. Synthesis of racemic 2-deutero-3-fluoro-alanine and its salts
SE7511733L (sv) * 1974-11-08 1976-05-10 Merck & Co Inc Syntes av recemisk 3-fluoro-alanin och salter derav, samt mellanprodukt i denna syntes
IE47542B1 (en) * 1977-06-01 1984-04-18 Merck & Co Inc Di-and tri-fluoromethyl amino acids and amines,compositions and processes for preparing said compounds
IE46910B1 (en) * 1977-06-01 1983-11-02 Merck & Co Inc Fluorinated alkylamines and process for preparing same
US4326071A (en) 1977-09-28 1982-04-20 Merrell Toraude Et Compagnie Halomethyl derivatives of gamma-aminobutyric acid and related compounds
US4264590A (en) * 1979-05-23 1981-04-28 Abbott Laboratories Antibacterial peptide

Also Published As

Publication number Publication date
EP0024965B1 (en) 1983-04-27
NO151319B (no) 1984-12-10
EP0024965A1 (en) 1981-03-11
AU6047680A (en) 1981-02-05
DK149269B (da) 1986-04-14
US4375477A (en) 1983-03-01
NO802218L (no) 1981-01-27
CA1161450A (en) 1984-01-31
ES493555A0 (es) 1981-07-01
DE3062893D1 (en) 1983-06-01
DK320680A (da) 1981-01-27
DK149269C (da) 1986-08-25
PH16349A (en) 1983-09-05
ES8105969A1 (es) 1981-07-01
AU536371B2 (en) 1984-05-03
NZ194348A (en) 1982-09-14

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