NO171504C - Analogifremgangsmaate for fremstilling av terapeutisk aktive fosfonyl-hydroksyacylproliner - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive fosfonyl-hydroksyacylproliner

Info

Publication number: NO171504C
Authority: NO; Norway
Prior art keywords: preparation; therapeutic active; prolines; analogy procedure; phosphonyl hydroxyacyl
Prior art date: 1986-01-06

Application number

NO870030A

Other languages

English (en)

Norwegian (no)

Other versions

NO870030D0 (no

NO171504B (no

NO870030L (no

Inventor

Donald Steven Karanewsky

Jr Edward William Petrillo

Original Assignee

Squibb & Sons Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-01-06

Filing date

1987-01-05

Publication date

1993-03-24

1987-01-05 Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc

1987-01-05 Publication of NO870030D0 publication Critical patent/NO870030D0/no

1987-07-07 Publication of NO870030L publication Critical patent/NO870030L/no

1992-12-14 Publication of NO171504B publication Critical patent/NO171504B/no

1993-03-24 Publication of NO171504C publication Critical patent/NO171504C/no

Links

150000003148 prolines Chemical class 0.000 title abstract 2
230000001225 therapeutic effect Effects 0.000 title 1
229940030600 antihypertensive agent Drugs 0.000 abstract 2
239000002220 antihypertensive agent Substances 0.000 abstract 2
OSUKSSHOHKZSJC-UHFFFAOYSA-N 12591-02-5 Chemical compound ClP(=O)=O OSUKSSHOHKZSJC-UHFFFAOYSA-N 0.000 abstract 1
102000004190 Enzymes Human genes 0.000 abstract 1
108090000790 Enzymes Proteins 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000003710 aryl alkyl group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000005764 inhibitory process Effects 0.000 abstract 1
XRBCRPZXSCBRTK-UHFFFAOYSA-N phosphonous acid Chemical compound OPO XRBCRPZXSCBRTK-UHFFFAOYSA-N 0.000 abstract 1
125000005499 phosphonyl group Chemical group 0.000 abstract 1
235000013930 proline Nutrition 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/572—Five-membered rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pyrrole Compounds (AREA)
Steroid Compounds (AREA)
Peptides Or Proteins (AREA)

NO870030A 1986-01-06 1987-01-05 Analogifremgangsmaate for fremstilling av terapeutisk aktive fosfonyl-hydroksyacylproliner NO171504C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/816,476 US4745196A (en)	1986-01-06	1986-01-06	Orally active phosphonyl hydroxyacyl prolines

Publications (4)

Publication Number	Publication Date
NO870030D0 NO870030D0 (no)	1987-01-05
NO870030L NO870030L (no)	1987-07-07
NO171504B NO171504B (no)	1992-12-14
NO171504C true NO171504C (no)	1993-03-24

Family

ID=25220723

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO870030A NO171504C (no)	1986-01-06	1987-01-05	Analogifremgangsmaate for fremstilling av terapeutisk aktive fosfonyl-hydroksyacylproliner

Country Status (25)

Country	Link
US (1)	US4745196A (de)
EP (2)	EP0350138B1 (de)
JP (1)	JPS62164691A (de)
KR (1)	KR900001612B1 (de)
CN (1)	CN1015264B (de)
AT (2)	ATE53215T1 (de)
AU (1)	AU592390B2 (de)
CA (1)	CA1279651C (de)
CS (1)	CS266599B2 (de)
DD (1)	DD258415A5 (de)
DE (2)	DE3671631D1 (de)
DK (1)	DK162894C (de)
ES (2)	ES2061945T3 (de)
FI (1)	FI85862C (de)
GR (1)	GR3000524T3 (de)
HU (1)	HU199490B (de)
IE (1)	IE59688B1 (de)
IL (1)	IL81154A (de)
NO (1)	NO171504C (de)
NZ (1)	NZ218475A (de)
PH (1)	PH24150A (de)
PL (1)	PL150341B1 (de)
PT (1)	PT84062B (de)
SU (1)	SU1709912A3 (de)
ZA (1)	ZA869058B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4931464A (en) *	1989-02-15	1990-06-05	E. R. Squibb & Sons, Inc.	Method of reducing pre- and post-ischemic myocardial arrhythmias and fibrillation
US4962095A (en) *	1989-02-15	1990-10-09	E. R. Squibb & Sons, Inc.	Method of reducing pre-and post-ischemic myocardial arrhythmias and fibrillation
US5282113A (en) *	1990-03-05	1994-01-25	Hitachi Maxell, Ltd.	Memory card with a plurality of contact spaces
NZ549739A (en)	2006-09-07	2009-01-31	Biovittoria Ltd	Sweetening compositions and processes for preparing them
WO2018077140A1 (en)	2016-10-24	2018-05-03	Guilin Gfs Monk Fruit Corporation	Extracts from fruits of the cucurbitaceae family, and methods of preparing thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4452791A (en) *	1982-03-15	1984-06-05	E. R. Squibb & Sons, Inc.	Aminoalkyl and related substituted phosphinic acid angiotensin converting enzyme inhibitors
US4452790A (en) *	1982-06-23	1984-06-05	E. R. Squibb & Sons, Inc.	Phosphonyl hydroxyacyl amino acid derivatives as antihypertensives

1986
- 1986-01-06 US US06/816,476 patent/US4745196A/en not_active Expired - Fee Related
- 1986-12-01 ZA ZA869058A patent/ZA869058B/xx unknown
- 1986-12-02 NZ NZ218475A patent/NZ218475A/xx unknown
- 1986-12-02 CA CA000524350A patent/CA1279651C/en not_active Expired - Lifetime
- 1986-12-05 AU AU66133/86A patent/AU592390B2/en not_active Ceased
- 1986-12-12 IE IE325086A patent/IE59688B1/en not_active IP Right Cessation
- 1986-12-15 PH PH34599A patent/PH24150A/en unknown
- 1986-12-22 DE DE8686310043T patent/DE3671631D1/de not_active Expired - Fee Related
- 1986-12-22 AT AT86310043T patent/ATE53215T1/de not_active IP Right Cessation
- 1986-12-22 ES ES89202047T patent/ES2061945T3/es not_active Expired - Lifetime
- 1986-12-22 DE DE3650106T patent/DE3650106T2/de not_active Expired - Fee Related
- 1986-12-22 ES ES86310043T patent/ES2015267B3/es not_active Expired - Lifetime
- 1986-12-22 EP EP89202047A patent/EP0350138B1/de not_active Expired - Lifetime
- 1986-12-22 AT AT89202047T patent/ATE113053T1/de not_active IP Right Cessation
- 1986-12-22 EP EP86310043A patent/EP0229520B1/de not_active Expired - Lifetime
- 1986-12-25 JP JP61315988A patent/JPS62164691A/ja active Granted
1987
- 1987-01-04 IL IL81154A patent/IL81154A/xx not_active IP Right Cessation
- 1987-01-05 DK DK002887A patent/DK162894C/da not_active IP Right Cessation
- 1987-01-05 PL PL1987263552A patent/PL150341B1/pl unknown
- 1987-01-05 NO NO870030A patent/NO171504C/no unknown
- 1987-01-05 HU HU8721A patent/HU199490B/hu not_active IP Right Cessation
- 1987-01-05 SU SU874028770A patent/SU1709912A3/ru active
- 1987-01-05 CS CS8796A patent/CS266599B2/cs unknown
- 1987-01-05 FI FI870029A patent/FI85862C/fi not_active IP Right Cessation
- 1987-01-05 KR KR1019870000007A patent/KR900001612B1/ko not_active Expired
- 1987-01-06 CN CN87100055A patent/CN1015264B/zh not_active Expired
- 1987-01-06 PT PT84062A patent/PT84062B/pt not_active IP Right Cessation
- 1987-01-06 DD DD87299115A patent/DD258415A5/de unknown
1990
- 1990-05-31 GR GR90400339T patent/GR3000524T3/el unknown

Also Published As

Publication number	Publication date
ZA869058B (en)	1987-07-29
FI85862B (fi)	1992-02-28
ES2015267B3 (es)	1990-08-16
DK2887A (da)	1987-07-07
NO870030D0 (no)	1987-01-05
IL81154A0 (en)	1987-08-31
PH24150A (en)	1990-03-22
CS266599B2 (en)	1990-01-12
PT84062A (en)	1987-02-01
US4745196A (en)	1988-05-17
CN1015264B (zh)	1992-01-01
PT84062B (pt)	1989-02-28
EP0229520A1 (de)	1987-07-22
IE863250L (en)	1987-07-06
IL81154A (en)	1991-08-16
IE59688B1 (en)	1994-03-23
DK162894C (da)	1992-05-18
ATE113053T1 (de)	1994-11-15
PL150341B1 (en)	1990-05-31
FI870029L (fi)	1987-07-07
AU6613386A (en)	1987-07-09
KR870007188A (ko)	1987-08-17
CS9687A2 (en)	1989-04-14
DD258415A5 (de)	1988-07-20
NO171504B (no)	1992-12-14
DE3650106T2 (de)	1995-08-10
GR3000524T3 (en)	1991-07-31
JPS62164691A (ja)	1987-07-21
EP0229520B1 (de)	1990-05-30
JPH0357115B2 (de)	1991-08-30
EP0350138A2 (de)	1990-01-10
EP0350138B1 (de)	1994-10-19
HU199490B (en)	1990-02-28
ES2061945T3 (es)	1994-12-16
CA1279651C (en)	1991-01-29
DK2887D0 (da)	1987-01-05
EP0350138A3 (en)	1990-01-24
CN87100055A (zh)	1987-08-05
SU1709912A3 (ru)	1992-01-30
ATE53215T1 (de)	1990-06-15
KR900001612B1 (ko)	1990-03-17
PL263552A1 (en)	1988-08-18
HUT43864A (en)	1987-12-28
NZ218475A (en)	1989-02-24
FI85862C (fi)	1992-06-10
DE3650106D1 (de)	1994-11-24
AU592390B2 (en)	1990-01-11
NO870030L (no)	1987-07-07
FI870029A0 (fi)	1987-01-05
DE3671631D1 (de)	1990-07-05
DK162894B (da)	1991-12-23

Publication	Publication Date	Title
AU570202B2 (en)	1988-03-10	Phosphinates containing an n-acylated acid substituted-n heterocycle
EP0249224A3 (de)	1989-01-25	Antihypertensives Mittel
DK389585A (da)	1986-03-01	Cis,endo-2-azabicycloalkan-3-carboxylsyre-derivater, deres fremstilling og anvendelse
NO161116C (no)	1989-07-05	Analogifremgangsmaate for fremstilling av antiviralt virksomme purinderivater.
TNSN87012A1 (fr)	1990-01-01	Nouveaux derives de dihydrobenzofuranne - et de chromane - carboxamides, leurs procedes de preparation et leur utilisation comme neuroleptiques
EP0199152A3 (de)	1987-11-04	Lypoxygenasehemmende Verbindungen
NO870030D0 (no)	1987-01-05	Fremgangsmaate for fremstilling av terapeutisk aktive fosfonylhydroksyacyproliner.
NO834884L (no)	1984-07-02	Fremgangsmaate for fremstilling av farmakologisk aktive nitroalifatiske forbindelser
NO173991C (no)	1994-03-02	Analogifremgangsmaate til fremstilling av terapeutisk aktive 1,2,5-ditiazocin-derivater
NO168580C (no)	1992-03-11	Analogifremgangsmaate ved fremstilling av terapeutisk aktive beta-methylen-furanethanaminer
DK0868428T3 (da)	2003-07-21	Phosphonsyrederivater med metallopeptidaseinhiberende aktivitet
ES543796A0 (es)	1986-01-01	Procedimiento de preparacion de nuevos derivados benzohi- drilpiperacinos y sus sales de adicion acidas
DE3782235D1 (de)	1992-11-19	Verwendung von 2-oxo-imidazolidin-derivaten zur prophylaxe und zur behandlung von herzinsuffizienz.
DK46884D0 (da)	1984-02-02	5-aminomethyl-imidazol-1-yl-1,3-dialkyl-1h-pyrazol-4-yl-aroyl-methanoner,fremgangsmaade til deres fremstilling samt deres anvendelse
ATE77373T1 (de)	1992-07-15	Verfahren zur herstellung von chinolinsaeurederivaten.