NO171787C - Analogifremgangsmaate for fremstilling av terapeutisk aktive 8-azabicyclo(3.2.1)oct-2-en-forbindelser - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive 8-azabicyclo(3.2.1)oct-2-en-forbindelser

Info

Publication number
NO171787C
NO171787C NO885052A NO885052A NO171787C NO 171787 C NO171787 C NO 171787C NO 885052 A NO885052 A NO 885052A NO 885052 A NO885052 A NO 885052A NO 171787 C NO171787 C NO 171787C
Authority
NO
Norway
Prior art keywords
azabicyclo
oct
compounds
preparation
therapeutic active
Prior art date
Application number
NO885052A
Other languages
English (en)
Norwegian (no)
Other versions
NO885052L (no
NO885052D0 (no
NO171787B (no
Inventor
Lone Nielsen
Frank Waetjen
Jens W Kindtler
Preben Houlberg Olesen
Per Sauerberg
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK595287A external-priority patent/DK595287D0/da
Priority claimed from DK687087A external-priority patent/DK687087D0/da
Priority claimed from DK110288A external-priority patent/DK110288D0/da
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of NO885052D0 publication Critical patent/NO885052D0/no
Publication of NO885052L publication Critical patent/NO885052L/no
Priority to NO912746A priority Critical patent/NO178303C/no
Priority to NO912745A priority patent/NO179791C/no
Publication of NO171787B publication Critical patent/NO171787B/no
Publication of NO171787C publication Critical patent/NO171787C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO885052A 1987-11-13 1988-11-11 Analogifremgangsmaate for fremstilling av terapeutisk aktive 8-azabicyclo(3.2.1)oct-2-en-forbindelser NO171787C (no)

Priority Applications (2)

Application Number Priority Date Filing Date Title
NO912746A NO178303C (no) 1987-11-13 1991-07-12 Analogifremgangsmåte for fremstilling av terapeutisk aktive kinuklidinforbindelser
NO912745A NO179791C (no) 1987-11-13 1991-07-12 Analogifremgangsmåte for fremstilling av terapeutisk aktive 1,2,5,6-tetrahydropyridinforbindelser

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK595287A DK595287D0 (da) 1987-11-13 1987-11-13 Azabicykliske forbindelser, deres fremstilling og anvendelse
DK687087A DK687087D0 (da) 1987-12-28 1987-12-28 Azacycliske forbindelser, deres fremstilling og anvendelse
DK110288A DK110288D0 (da) 1988-03-02 1988-03-02 Azacykliske forbindelser, deres fremstilling og anvendelse

Publications (4)

Publication Number Publication Date
NO885052D0 NO885052D0 (no) 1988-11-11
NO885052L NO885052L (no) 1989-05-16
NO171787B NO171787B (no) 1993-01-25
NO171787C true NO171787C (no) 1993-05-05

Family

ID=27221113

Family Applications (1)

Application Number Title Priority Date Filing Date
NO885052A NO171787C (no) 1987-11-13 1988-11-11 Analogifremgangsmaate for fremstilling av terapeutisk aktive 8-azabicyclo(3.2.1)oct-2-en-forbindelser

Country Status (15)

Country Link
US (2) US5262427A (de)
EP (1) EP0316718B1 (de)
JP (1) JP2831362B2 (de)
KR (1) KR890008139A (de)
AU (1) AU619770B2 (de)
CA (1) CA1340943C (de)
DE (1) DE3884140T2 (de)
ES (1) ES2059469T3 (de)
FI (1) FI95799C (de)
IE (1) IE63906B1 (de)
IL (1) IL88156A (de)
NO (1) NO171787C (de)
NZ (1) NZ226936A (de)
PH (1) PH25289A (de)
PT (1) PT88993B (de)

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Also Published As

Publication number Publication date
KR890008139A (ko) 1989-07-10
US5262427A (en) 1993-11-16
NO885052L (no) 1989-05-16
IE63906B1 (en) 1995-06-14
FI95799B (fi) 1995-12-15
EP0316718A3 (en) 1989-12-20
CA1340943C (en) 2000-04-04
IL88156A (en) 1997-02-18
NZ226936A (en) 1991-02-26
PT88993A (pt) 1989-11-30
PH25289A (en) 1991-04-30
DE3884140T2 (de) 1994-01-13
IL88156A0 (en) 1989-06-30
FI885223A7 (fi) 1989-05-14
EP0316718A2 (de) 1989-05-24
EP0316718B1 (de) 1993-09-15
IE883208L (en) 1989-05-13
US5356912A (en) 1994-10-18
JPH01153688A (ja) 1989-06-15
NO885052D0 (no) 1988-11-11
DE3884140D1 (de) 1993-10-21
PT88993B (pt) 1993-05-31
NO171787B (no) 1993-01-25
AU619770B2 (en) 1992-02-06
FI95799C (fi) 1996-03-25
AU2460888A (en) 1989-05-18
ES2059469T3 (es) 1994-11-16
JP2831362B2 (ja) 1998-12-02
FI885223A0 (fi) 1988-11-11

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