NO173499C - Analogifremgangsmaate for fremstilling av terapeutisk aktive kinoxalinforbindelser - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive kinoxalinforbindelser

Info

Publication number: NO173499C
Authority: NO; Norway
Prior art keywords: preparation; therapeutically active; compounds; analogous procedures; quinoxaline compounds
Prior art date: 1986-09-16

Application number

NO873873A

Other languages

English (en)

Norwegian (no)

Other versions

NO173499B (no

NO873873L (no

NO873873D0 (no

Inventor

Tage Honore

Joergen Drejer

Poul Jacobsen

Flemming Elmelund Nielsen

Original Assignee

Novo Nordisk As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-09-16

Filing date

1987-09-15

Publication date

1993-12-22

1987-09-15 Application filed by Novo Nordisk As filed Critical Novo Nordisk As

1987-09-15 Publication of NO873873D0 publication Critical patent/NO873873D0/no

1988-03-17 Publication of NO873873L publication Critical patent/NO873873L/no

1993-09-13 Publication of NO173499B publication Critical patent/NO173499B/no

1993-12-22 Publication of NO173499C publication Critical patent/NO173499C/no

Links

238000000034 method Methods 0.000 title abstract 2
125000001567 quinoxalinyl group Chemical class N1=C(C=NC2=CC=CC=C12)* 0.000 title 1
HSFWRNGVRCDJHI-UHFFFAOYSA-N alpha-acetylene Natural products C#C HSFWRNGVRCDJHI-UHFFFAOYSA-N 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
125000002534 ethynyl group Chemical group [H]C#C* 0.000 abstract 2
102000003678 AMPA Receptors Human genes 0.000 abstract 1
108090000078 AMPA Receptors Proteins 0.000 abstract 1
-1 Heterocyclic dihydroxyquinoxaline compounds Chemical class 0.000 abstract 1
JCXJVPUVTGWSNB-UHFFFAOYSA-N Nitrogen dioxide Chemical compound O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 abstract 1
230000002964 excitative effect Effects 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
208000013403 hyperactivity Diseases 0.000 abstract 1
239000002858 neurotransmitter agent Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Neurology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Steroid Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

NO873873A 1986-09-16 1987-09-15 Analogifremgangsmaate for fremstilling av terapeutisk aktive kinoxalinforbindelser NO173499C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US90786586A	1986-09-16	1986-09-16

Publications (4)

Publication Number	Publication Date
NO873873D0 NO873873D0 (no)	1987-09-15
NO873873L NO873873L (no)	1988-03-17
NO173499B NO173499B (no)	1993-09-13
NO173499C true NO173499C (no)	1993-12-22

Family

ID=25424773

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO873873A NO173499C (no)	1986-09-16	1987-09-15	Analogifremgangsmaate for fremstilling av terapeutisk aktive kinoxalinforbindelser

Country Status (12)

Country	Link
EP (1)	EP0260467B1 (de)
JP (1)	JPS6383074A (de)
AT (1)	ATE99296T1 (de)
CA (1)	CA1298298C (de)
DE (1)	DE3788612T2 (de)
DK (1)	DK161319C (de)
ES (1)	ES2061456T3 (de)
FI (1)	FI88718C (de)
IE (1)	IE66149B1 (de)
NO (1)	NO173499C (de)
PT (1)	PT85727B (de)
ZA (1)	ZA876312B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK716188D0 (da) *	1988-12-22	1988-12-22	Ferrosan As	Quinoxalinforbindelser, deres fremstilling og anvendelse
HU221425B (en) *	1990-11-06	2002-10-28	Yamanouchi Pharma Co Ltd	Condensed pyrazine derivatives, process for their production and pharmaceutical preparations containing these compounds
PT99864B (pt) *	1990-12-21	1999-06-30	Schering Ag	Processo para a preparacao de novas composicoes farmaceuticas contendo antagonistas de receptor de quisqualato
DK73091D0 (da) *	1991-04-22	1991-04-22	Novo Nordisk As	Quinoxalinforbindelser, deres fremstilling og anvendelse
DK0647137T3 (da) *	1992-06-22	2008-12-08	State Of Oregon Through Oregon	Glycinreceptorantagonister og anvendelse deraf
AU688459B2 (en) *	1994-04-08	1998-03-12	Shionogi & Co., Ltd.	Oxopyridinylquinoxaline derivative
DE4428152A1 (de) *	1994-06-22	1996-01-04	Basf Ag	Neue Amido-chinoxalindione, ihrer Herstellung und Verwendung
AU3650695A (en) *	1994-09-30	1996-04-26	Basf Aktiengesellschaft	New heterocyclic substituted imidazoloquinoxalinones, their preparation and their use
DE4436852A1 (de) *	1994-10-14	1996-04-18	Basf Ag	Pyrrolyl-tetrahydrobenzochinoxalindione, ihre Herstellung und Verwendung
DE19521058A1 (de) *	1995-06-09	1996-12-12	Basf Ag	Verfahren zur Herstellung von Aromaten enthaltenden Polyetherpolyolen
US5719153A (en) *	1995-08-15	1998-02-17	American Home Products Corporation	5H,8H-2-oxa-1,3,5,8-tetraaza-cyclopenta b!-naphthalene-6,7-diones
FR2743363A1 (fr) *	1996-01-10	1997-07-11	Rhone Poulenc Rorer Sa	5h,10h-imidazo(1,2-a)indeno(1,2-e)pyrazine-a-ones substituees en position 2, leur preparation et les medicaments les contenant
DE19624808A1 (de)	1996-06-21	1998-01-02	Basf Ag	Pyrrolylchinoxalindione, ihre Herstellung und Verwendung
EP3427729A1 (de)	2017-07-13	2019-01-16	Paris Sciences et Lettres - Quartier Latin	Probenecid zur behandlung von epileptischen erkrankungen, störungen oder zuständen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3992378A (en) *	1973-12-26	1976-11-16	Eli Lilly And Company	Fluoralkyl quinoxadinediones
EP0107455B1 (de) *	1982-10-18	1986-07-09	Pfizer Inc.	Triazoloquinoxaline als Antidepressions- und Antiermüdungsmittel

1987
- 1987-08-13 IE IE216587A patent/IE66149B1/en not_active IP Right Cessation
- 1987-08-19 AT AT87112060T patent/ATE99296T1/de active
- 1987-08-19 DE DE87112060T patent/DE3788612T2/de not_active Expired - Fee Related
- 1987-08-19 EP EP87112060A patent/EP0260467B1/de not_active Expired - Lifetime
- 1987-08-19 ES ES87112060T patent/ES2061456T3/es not_active Expired - Lifetime
- 1987-08-25 ZA ZA876312A patent/ZA876312B/xx unknown
- 1987-09-01 FI FI873790A patent/FI88718C/fi not_active IP Right Cessation
- 1987-09-10 DK DK471687A patent/DK161319C/da not_active IP Right Cessation
- 1987-09-15 NO NO873873A patent/NO173499C/no unknown
- 1987-09-16 JP JP62229957A patent/JPS6383074A/ja active Granted
- 1987-09-16 CA CA000547085A patent/CA1298298C/en not_active Expired - Lifetime
- 1987-09-16 PT PT85727A patent/PT85727B/pt not_active IP Right Cessation

Also Published As

Publication number	Publication date
NO173499B (no)	1993-09-13
DE3788612D1 (de)	1994-02-10
DK161319C (da)	1991-12-09
FI873790L (fi)	1988-03-17
DE3788612T2 (de)	1994-04-28
IE66149B1 (en)	1995-12-13
EP0260467B1 (de)	1993-12-29
DK471687A (da)	1988-03-17
FI873790A0 (fi)	1987-09-01
FI88718B (fi)	1993-03-15
NO873873L (no)	1988-03-17
PT85727A (en)	1987-10-01
NO873873D0 (no)	1987-09-15
ES2061456T3 (es)	1994-12-16
DK471687D0 (da)	1987-09-10
ATE99296T1 (de)	1994-01-15
ZA876312B (en)	1988-02-24
PT85727B (pt)	1990-08-31
JPH0532391B2 (de)	1993-05-14
EP0260467A2 (de)	1988-03-23
JPS6383074A (ja)	1988-04-13
IE872165L (en)	1988-03-16
CA1298298C (en)	1992-03-31
FI88718C (fi)	1993-06-28
EP0260467A3 (en)	1990-02-07
DK161319B (da)	1991-06-24

Publication	Publication Date	Title
ES2062050T3 (es)	1994-12-16	Derivados de piperazinilo.
FI92582B (fi)	1994-08-31	Menetelmä uusien terapeuttisesti käyttökelpoisten kinoksaliinijohdannaisten valmistamiseksi
PT87552A (pt)	1989-05-31	Process for the preparation of novel tetrazole intermediates toantihypertensive compounds
FI843864A0 (fi)	1984-10-02	2-amino-5-hydroxy-4 -metylpyrimidinderivat.
FI810604L (fi)	1981-08-30	Foerfarande foer framstaellning av indanderivat
DE68906609D1 (de)	1993-06-24	Dopamin-vorlaeufer.
EP0260467A3 (en)	1990-02-07	Quinoxaline compounds and their preparation and use
NO178661C (no)	1996-05-08	Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoksalinforbindelser
TNSN87012A1 (fr)	1990-01-01	Nouveaux derives de dihydrobenzofuranne - et de chromane - carboxamides, leurs procedes de preparation et leur utilisation comme neuroleptiques
ATE71078T1 (de)	1992-01-15	Glyzerinderivate.
FR2378741A1 (fr)	1978-08-25	Acides garyl goxo isovaleriques doues de proprietes antiphlogistiques et antalgiques
NO164474C (no)	1990-10-10	Analogifremgangsmaate for fremstilling av terapeutisk aktive heksahydropyrrolo(2,1-a)isokinolin-derivater.
DE3884878D1 (de)	1993-11-18	Uricosuretische Zusammensetzung.
FR2365569A1 (fr)	1978-04-21	Nouveaux acides carboxyliques pyrimido (1,2a)-heterocycliques, procede de preparation de ces corps et compositions pharmaceutiques qui les contiennent