NO176476C - Analogifremgangsmåte for fremstilling av 2-pyridoner samt ketonmellomprodukter til bruk ved fremgangsmåten - Google Patents
Analogifremgangsmåte for fremstilling av 2-pyridoner samt ketonmellomprodukter til bruk ved fremgangsmåtenInfo
- Publication number
- NO176476C NO176476C NO894814A NO894814A NO176476C NO 176476 C NO176476 C NO 176476C NO 894814 A NO894814 A NO 894814A NO 894814 A NO894814 A NO 894814A NO 176476 C NO176476 C NO 176476C
- Authority
- NO
- Norway
- Prior art keywords
- optionally substituted
- pyridones
- preparation
- analogous
- ketone intermediates
- Prior art date
Links
- UBQKCCHYAOITMY-UHFFFAOYSA-N pyridin-2-ol Chemical class OC1=CC=CC=N1 UBQKCCHYAOITMY-UHFFFAOYSA-N 0.000 title abstract 2
- 239000000543 intermediate Substances 0.000 title 1
- 150000002576 ketones Chemical class 0.000 title 1
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 125000000547 substituted alkyl group Chemical group 0.000 abstract 2
- 125000003107 substituted aryl group Chemical group 0.000 abstract 2
- 102000004286 Hydroxymethylglutaryl CoA Reductases Human genes 0.000 abstract 1
- 108090000895 Hydroxymethylglutaryl CoA Reductases Proteins 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 235000012000 cholesterol Nutrition 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- -1 imino, amino Chemical group 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/70—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3841991A DE3841991A1 (de) | 1988-12-14 | 1988-12-14 | Substituierte 2-pyridone und pyrid-2-thione, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
| IT8920861A IT8920861A0 (it) | 1989-06-13 | 1989-06-13 | 2 pirodoni e pirid 2 tioni sostituiti, processo per produrli e loro impiego in medicinali. |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO894814D0 NO894814D0 (no) | 1989-12-01 |
| NO894814L NO894814L (no) | 1990-06-15 |
| NO176476B NO176476B (no) | 1995-01-02 |
| NO176476C true NO176476C (no) | 1995-04-12 |
Family
ID=25875117
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO894814A NO176476C (no) | 1988-12-14 | 1989-12-01 | Analogifremgangsmåte for fremstilling av 2-pyridoner samt ketonmellomprodukter til bruk ved fremgangsmåten |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5032602A (no) |
| EP (1) | EP0373423B1 (no) |
| JP (1) | JP2954954B2 (no) |
| CN (1) | CN1032203C (no) |
| AT (1) | ATE100086T1 (no) |
| CA (1) | CA2005206A1 (no) |
| DE (1) | DE58906708D1 (no) |
| DK (1) | DK630489A (no) |
| ES (1) | ES2061902T3 (no) |
| FI (1) | FI92196C (no) |
| HU (2) | HUT59907A (no) |
| IE (1) | IE63401B1 (no) |
| IL (1) | IL92632A0 (no) |
| NO (1) | NO176476C (no) |
| NZ (1) | NZ231707A (no) |
| PT (1) | PT92550B (no) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL98526A0 (en) * | 1990-06-18 | 1992-07-15 | Merck & Co Inc | Pyridones,processes for their preparation and pharmaceutical compositions containing them |
| US5308854A (en) * | 1990-06-18 | 1994-05-03 | Merck & Co., Inc. | Inhibitors of HIV reverse transcriptase |
| AU660132B2 (en) * | 1992-12-21 | 1995-06-08 | Bayer Aktiengesellschaft | Substituted 4-phenyl-pyridones and 4-phenyl-2-alkoxypyridine |
| AR008789A1 (es) | 1996-07-31 | 2000-02-23 | Bayer Corp | Piridinas y bifenilos substituidos |
| US6867217B1 (en) | 1999-05-19 | 2005-03-15 | Pharmacia Corporation | Substituted polycyclic aryl and heteroaryl pyridones useful for selective inhibition of the coagulation cascade |
| US6710058B2 (en) * | 2000-11-06 | 2004-03-23 | Bristol-Myers Squibb Pharma Company | Monocyclic or bicyclic carbocycles and heterocycles as factor Xa inhibitors |
| ES2334990T3 (es) * | 2002-02-14 | 2010-03-18 | Pharmacia Corporation | Piridinonas sustituidas como moduladores de p38 map quinasa. |
| TW200307667A (en) * | 2002-05-06 | 2003-12-16 | Bristol Myers Squibb Co | Sulfonylaminovalerolactams and derivatives thereof as factor Xa inhibitors |
| GB0420722D0 (en) * | 2004-09-17 | 2004-10-20 | Addex Pharmaceuticals Sa | Novel allosteric modulators |
| TWI417095B (zh) * | 2006-03-15 | 2013-12-01 | Janssen Pharmaceuticals Inc | １，４-二取代之３-氰基-吡啶酮衍生物及其作為ｍＧｌｕＲ２-受體之正向異位性調節劑之用途 |
| TW200845978A (en) * | 2007-03-07 | 2008-12-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives |
| TW200900065A (en) | 2007-03-07 | 2009-01-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives |
| KR20100080597A (ko) * | 2007-09-14 | 2010-07-09 | 오르토-맥닐-얀센 파마슈티칼스 인코포레이티드 | １,３-이치환된-４-페닐-1ｈ-피리딘-2-온 |
| CA2696948C (en) * | 2007-09-14 | 2013-04-30 | Jose Maria Cid-Nunez | 1',3'-disubstituted-4-phenyl-3,4,5,6-tetrahydro-2h,1'h-[1,4']bipyridinyl-2'-ones |
| KR20100065191A (ko) | 2007-09-14 | 2010-06-15 | 오르토-맥닐-얀센 파마슈티칼스 인코포레이티드 | １,３-이치환된 ４-(아릴-ｘ-페닐)-１ｈ-피리딘-２-온 |
| EP2220083B1 (en) * | 2007-11-14 | 2017-07-19 | Janssen Pharmaceuticals, Inc. | Imidazo[1,2-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
| CA2735764C (en) | 2008-09-02 | 2016-06-14 | Ortho-Mcneil-Janssen Pharmaceuticals, Inc. | 3-azabicyclo[3.1.0]hexyl derivatives as modulators of metabotropic glutamate receptors |
| AU2009304293B2 (en) | 2008-10-16 | 2012-04-26 | Addex Pharma S.A. | Indole and benzomorpholine derivatives as modulators of metabotropic glutamate receptors |
| BRPI0921333A2 (pt) | 2008-11-28 | 2015-12-29 | Addex Pharmaceuticals Sa | derivados de indol e benzoxazina como moduladores de receptores de glutamato metabotrópicos |
| MY153913A (en) | 2009-05-12 | 2015-04-15 | Janssen Pharmaceuticals Inc | 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
| EA020671B1 (ru) | 2009-05-12 | 2014-12-30 | Янссен Фармасьютикалз, Инк. | ПРОИЗВОДНЫЕ 1,2,4-ТРИАЗОЛО[4,3-a]ПИРИДИНА И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ ПОЛОЖИТЕЛЬНЫХ АЛЛОСТЕРИЧЕСКИХ МОДУЛЯТОРОВ РЕЦЕПТОРОВ mGluR2 |
| NZ596078A (en) | 2009-05-12 | 2013-06-28 | Janssen Pharmaceuticals Inc | 1,2,4-TRIAZOLO [4,3-a] PYRIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OR PREVENTION OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS |
| EP2643320B1 (en) | 2010-11-08 | 2015-03-04 | Janssen Pharmaceuticals, Inc. | 1,2,4-TRIAZOLO[4,3-a]PYRIDINE DERIVATIVES AND THEIR USE AS POSITIVE ALLOSTERIC MODULATORS OF MGLUR2 RECEPTORS |
| CN103298810B (zh) | 2010-11-08 | 2016-03-16 | 杨森制药公司 | 1,2,4-三唑并[4,3-a]吡啶衍生物及其作为MGLUR2受体的正变构调节剂的用途 |
| CA2815002C (en) | 2010-11-08 | 2019-10-22 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
| JO3368B1 (ar) | 2013-06-04 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2 |
| JO3367B1 (ar) | 2013-09-06 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2 |
| LT3431106T (lt) | 2014-01-21 | 2021-02-10 | Janssen Pharmaceutica Nv | Deriniai, apimantys 2 potipio metabotropinio glutamaterginio receptoriaus teigiamus alosterinius moduliatorius arba ortosterinius agonistus, ir jų panaudojimas |
| KR102414246B1 (ko) | 2014-01-21 | 2022-06-27 | 얀센 파마슈티카 엔.브이. | 대사 조절형 글루탐산 작동성 수용체 제2아형의 양성 알로스테릭 조절제 또는 오르토스테릭 작동제를 포함하는 조합 및 그 용도 |
| US10260017B2 (en) | 2015-12-22 | 2019-04-16 | Eastman Chemical Company | Compounds and mixtures with antidegradant and antifatigue efficacy and compositions including said compounds |
| US10287418B2 (en) | 2015-12-22 | 2019-05-14 | Eastman Chemical Company | Compounds with antidegradant and antifatigue efficacy and compositions including said compounds |
| US10167252B2 (en) | 2015-12-22 | 2019-01-01 | Eastman Chemical Company | Compounds and mixtures with antidegradant and antifatigue efficacy and compositions including such compounds |
| US10160718B2 (en) | 2015-12-22 | 2018-12-25 | Eastman Chemical Company | Methods of making compounds having antidegradant and antifatigue efficacy |
| US10428009B2 (en) * | 2015-12-22 | 2019-10-01 | Eastman Chemical Company | Methods of making compounds and mixtures having antidegradant and antifatigue efficacy |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE758759A (fr) * | 1969-11-12 | 1971-05-10 | Merck & Co Inc | Pyridones anti-inflammatoires |
-
1989
- 1989-11-27 US US07/441,806 patent/US5032602A/en not_active Expired - Fee Related
- 1989-11-29 DE DE89122067T patent/DE58906708D1/de not_active Expired - Fee Related
- 1989-11-29 EP EP89122067A patent/EP0373423B1/de not_active Expired - Lifetime
- 1989-11-29 ES ES89122067T patent/ES2061902T3/es not_active Expired - Lifetime
- 1989-11-29 AT AT89122067T patent/ATE100086T1/de active
- 1989-12-01 NO NO894814A patent/NO176476C/no unknown
- 1989-12-11 IL IL92632A patent/IL92632A0/xx not_active IP Right Cessation
- 1989-12-11 NZ NZ231707A patent/NZ231707A/en unknown
- 1989-12-12 FI FI895925A patent/FI92196C/fi not_active IP Right Cessation
- 1989-12-12 PT PT92550A patent/PT92550B/pt not_active IP Right Cessation
- 1989-12-12 CA CA002005206A patent/CA2005206A1/en not_active Abandoned
- 1989-12-13 IE IE398789A patent/IE63401B1/en not_active IP Right Cessation
- 1989-12-13 DK DK630489A patent/DK630489A/da not_active Application Discontinuation
- 1989-12-14 HU HU91647A patent/HUT59907A/hu unknown
- 1989-12-14 CN CN89109399A patent/CN1032203C/zh not_active Expired - Fee Related
- 1989-12-14 HU HU896603A patent/HU210056B/hu not_active IP Right Cessation
- 1989-12-14 JP JP1322771A patent/JP2954954B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US5032602A (en) | 1991-07-16 |
| IE893987L (en) | 1990-06-14 |
| CN1043501A (zh) | 1990-07-04 |
| FI92196C (fi) | 1994-10-10 |
| PT92550B (pt) | 1996-06-28 |
| HU910647D0 (en) | 1991-09-30 |
| HU896603D0 (en) | 1990-02-28 |
| IE63401B1 (en) | 1995-04-19 |
| EP0373423A1 (de) | 1990-06-20 |
| DE58906708D1 (de) | 1994-02-24 |
| HUT59907A (en) | 1992-07-28 |
| HU210056B (en) | 1995-01-30 |
| PT92550A (pt) | 1990-06-29 |
| DK630489A (da) | 1990-06-15 |
| JPH02258766A (ja) | 1990-10-19 |
| NZ231707A (en) | 1992-06-25 |
| NO894814D0 (no) | 1989-12-01 |
| JP2954954B2 (ja) | 1999-09-27 |
| ATE100086T1 (de) | 1994-01-15 |
| ES2061902T3 (es) | 1994-12-16 |
| IL92632A0 (en) | 1990-08-31 |
| NO176476B (no) | 1995-01-02 |
| FI92196B (fi) | 1994-06-30 |
| CN1032203C (zh) | 1996-07-03 |
| EP0373423B1 (de) | 1994-01-12 |
| FI895925A0 (fi) | 1989-12-12 |
| NO894814L (no) | 1990-06-15 |
| CA2005206A1 (en) | 1990-06-14 |
| DK630489D0 (da) | 1989-12-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| FI895925A0 (fi) | Menetelmä terapeuttisesti käyttökelpoisten 2-pyridonien valmistamiseksi | |
| ES2101960T3 (es) | Lactamas benzo-condensadas. | |
| ES2167371T3 (es) | Derivados de 1h-3-aril-pirrolidin-2,4-diona espirociclicos substituidos. | |
| AU673111B2 (en) | Compounds containing a fused multiple ring lactam | |
| DE69528000D1 (de) | Zwischenprodukte zur Hertellung von Oxazolidindion- und Thiazolidindionderivate | |
| NO2003005I2 (no) | Substituerte isoxazoler, farmasoytisk preparat inneholdende slike forbindelser, fremgangsmâte for deres fremstilling og anvendelse derav, samt mellomprodukter | |
| DK175689A (da) | 4-acylcephemsulfon- eller 3-acylpenamsulfonforbindelser, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende samme | |
| NO823836L (no) | Fremgangsmaate ved fremstilling av antifibrinolytisk aktive forbindelser. | |
| ES2185634T3 (es) | Derivados de cefalosporina. | |
| EA200000551A1 (ru) | α-ГИДРОКСИ, -АМИНО И ГАЛОИДНЫЕ ПРОИЗВОДНЫЕ β-СУЛЬФОНИЛГИДРОКСАМОВЫХ КИСЛОТ В КАЧЕСТВЕ ИНГИБИТОРОВ МАТРИКСНЫХ МЕТАЛЛОПРОТЕИНАЗ | |
| ATE14880T1 (de) | Cephalosporinverbindungen und ihre herstellung. | |
| DK497580A (da) | Fremgangsmaade til fremstilling af indolbenzoxaniner | |
| FI940306L (fi) | Menetelmä kiraalisten tiatsolidiini-2,4-dionijohdannaisten synteesissä tarvittavien välituotteiden valmistamiseksi | |
| SE9202476D0 (sv) | Mellanprodukter foer framstaellning av epipodofyllotoxin och beslaektade foereningar och foerfaranden foer framstaellning och anvaendning daerav | |
| ES2065478T3 (es) | 2-amino-1,2,3,4-tetrahidronaftalenos y 3-aminocromanos sustituidos en el anillo. | |
| ES555820A0 (es) | Procedimiento para la obtencion de 1-aril-5-alcoxiiminoalquilamino-pirazoles | |
| NO306297B1 (no) | FremgangsmÕte for fremstilling av HIV-proteaseinhibitorer | |
| DK369289A (da) | Anvendelse af imidazopyrazolderivater som analgetica og antiinflammatoriske midler | |
| SE8704792D0 (sv) | Azole derivatives | |
| SE8000298L (sv) | Karbamatderivat av merkaptoacylhydroxiproliner | |
| IE43116L (en) | Oxadiazolidine derivatives | |
| NO940226D0 (no) | Chirale mellomprodukter for fremstilling av antidiabetiske tiazol er | |
| TH33561A (th) | กระบวนการเตรียมอนุพันธ์ 1,5-เบนโซไธอะเซพีน | |
| EP0569139A3 (en) | Alkyl substituted nitrotoluene derivatives | |
| IL80525A (en) | Preparation of indolines by cyclodehydrating 2-(2'-aminoethylphenyl)-ethanol in the presence of amorphous aluminium silicate catalyst |