NO178374C - Analogifremgangsmåte for fremstilling av nye terapeutisk aktive acetylcholinesteraseinhibitorer - Google Patents

Analogifremgangsmåte for fremstilling av nye terapeutisk aktive acetylcholinesteraseinhibitorer

Info

Publication number: NO178374C
Authority: NO; Norway
Prior art keywords: preparation; therapeutically active; acetylcholinesterase inhibitors; analogous process; new therapeutically
Prior art date: 1989-06-22

Application number

NO902776A

Other languages

English (en)

Norwegian (no)

Other versions

NO902776L (no

NO902776D0 (no

NO178374B (no

Inventor

Daniel Schirlin

Jean-Noel Collard

Jean-Marie Hornsperger

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-06-22

Filing date

1990-06-21

Publication date

1996-03-13

1990-06-21 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1990-06-21 Publication of NO902776D0 publication Critical patent/NO902776D0/no

1990-12-27 Publication of NO902776L publication Critical patent/NO902776L/no

1995-12-04 Publication of NO178374B publication Critical patent/NO178374B/no

1996-03-13 Publication of NO178374C publication Critical patent/NO178374C/no

Links

239000000544 cholinesterase inhibitor Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Silicates, Zeolites, And Molecular Sieves (AREA)

NO902776A 1989-06-22 1990-06-21 Analogifremgangsmåte for fremstilling av nye terapeutisk aktive acetylcholinesteraseinhibitorer NO178374C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP89401775A EP0403713A1 (de)	1989-06-22	1989-06-22	Acetylcholinesterase-Inhibitoren

Publications (4)

Publication Number	Publication Date
NO902776D0 NO902776D0 (no)	1990-06-21
NO902776L NO902776L (no)	1990-12-27
NO178374B NO178374B (no)	1995-12-04
NO178374C true NO178374C (no)	1996-03-13

Family

ID=8202963

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO902776A NO178374C (no)	1989-06-22	1990-06-21	Analogifremgangsmåte for fremstilling av nye terapeutisk aktive acetylcholinesteraseinhibitorer

Country Status (19)

Country	Link
EP (2)	EP0403713A1 (de)
JP (1)	JP2879951B2 (de)
KR (1)	KR0139529B1 (de)
CN (1)	CN1027759C (de)
AR (1)	AR247214A1 (de)
AT (1)	ATE119535T1 (de)
AU (1)	AU626428B2 (de)
CA (1)	CA2019231C (de)
DE (1)	DE69017543T2 (de)
DK (1)	DK0409676T3 (de)
ES (1)	ES2072406T3 (de)
FI (1)	FI97619C (de)
HU (1)	HU210569B (de)
IE (1)	IE66155B1 (de)
IL (1)	IL94779A (de)
NO (1)	NO178374C (de)
NZ (1)	NZ234136A (de)
PT (1)	PT94449B (de)
ZA (1)	ZA904715B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5523442A (en) *	1993-02-16	1996-06-04	Merrell Pharmaceuticals Inc.	Silylated acetylcholinesterase inhibitors
EP0611769A1 (de) *	1993-02-16	1994-08-24	Merrell Dow Pharmaceuticals Inc.	Silytierte acetylcholinesterase Inhibitoren
EP0627400A1 (de) *	1993-06-04	1994-12-07	Merrell Dow Pharmaceuticals Inc.	Aromatische Inhibitoren von Acetylcholinesterase
US5554780A (en) *	1994-05-05	1996-09-10	Merrell Pharmaceuticals Inc.	Process for the preparation of 1-(3-trialkylsilylphenyl)-2,2,2-trifluoromethyl ethanone derivatives
US5486638A (en) *	1994-11-08	1996-01-23	Marion Merrell Dow Inc.	Process for the preparation of 1-halo-3-trialkysilanyl-benzene derivatives
EP0749972A1 (de)	1995-06-21	1996-12-27	Merrell Pharmaceuticals Inc.	Verfahren zur Herstellung von 1-(3-trialkylsilylphenyl)-2,2,2-trifluormethylethanonderivaten
US6673784B1 (en)	1996-03-19	2004-01-06	G. D. Searle & Co.	Electrophilic ketones for the treatment of herpesvirus infections
CN1059702C (zh) *	1997-12-30	2000-12-20	中国科学院上海细胞生物学研究所	从哺乳类细胞中获得脑型乙酰胆碱酯酶的方法
US6218383B1 (en)	1998-08-07	2001-04-17	Targacept, Inc.	Pharmaceutical compositions for the prevention and treatment of central nervous system disorders
US6084117A (en) *	1999-11-22	2000-07-04	Albemarle Corporation	Production of silated haloarenes by selective silylation of polyhaloarenes
AU2011215870B2 (en)	2010-02-09	2016-01-28	The Johns Hopkins University	Methods and compositions for improving cognitive function
US20140206667A1 (en)	2012-11-14	2014-07-24	Michela Gallagher	Methods and compositions for treating schizophrenia
PL2931276T3 (pl)	2012-12-13	2018-06-29	H. Lundbeck A/S	Kompozycje zawierające wortioksetynę i donepezil
WO2014144663A1 (en)	2013-03-15	2014-09-18	The Johns Hopkins University	Methods and compositions for improving cognitive function
JP6433482B2 (ja)	2013-03-15	2018-12-05	エージンバイオ，インコーポレイテッド	認知機能を改善するための方法および組成物
WO2016191288A1 (en)	2015-05-22	2016-12-01	Agenebio, Inc.	Extended release pharmaceutical compositions of levetiracetam
CN112826794B (zh)	2019-11-06	2022-02-11	上海交通大学医学院	一种靶向修复神经血管病变的纳米复合物及其制备与应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL25820A (en) *	1966-05-22	1971-02-25	Yissum Res Dev Co	Silicon containing beta-hydroxy alpha-phenyl carboxylic acids,their amide and ester derivatives and intermediates for their preparation
US4835099A (en) *	1986-11-20	1989-05-30	Becton, Dickinson And Company	Signal enhancement in immunoassay by modulation of enzymatic catalysis

1989
- 1989-06-22 EP EP89401775A patent/EP0403713A1/de not_active Withdrawn
1990
- 1990-06-18 ZA ZA904715A patent/ZA904715B/xx unknown
- 1990-06-18 CA CA002019231A patent/CA2019231C/en not_active Expired - Lifetime
- 1990-06-19 IL IL9477990A patent/IL94779A/en not_active IP Right Cessation
- 1990-06-19 AU AU57584/90A patent/AU626428B2/en not_active Ceased
- 1990-06-19 NZ NZ234136A patent/NZ234136A/xx unknown
- 1990-06-20 HU HU903933A patent/HU210569B/hu not_active IP Right Cessation
- 1990-06-20 AR AR90317164A patent/AR247214A1/es active
- 1990-06-20 AT AT90401745T patent/ATE119535T1/de not_active IP Right Cessation
- 1990-06-20 ES ES90401745T patent/ES2072406T3/es not_active Expired - Lifetime
- 1990-06-20 DK DK90401745.6T patent/DK0409676T3/da active
- 1990-06-20 DE DE69017543T patent/DE69017543T2/de not_active Expired - Lifetime
- 1990-06-20 EP EP90401745A patent/EP0409676B1/de not_active Expired - Lifetime
- 1990-06-20 FI FI903104A patent/FI97619C/fi active IP Right Grant
- 1990-06-21 KR KR1019900009196A patent/KR0139529B1/ko not_active Expired - Fee Related
- 1990-06-21 IE IE225290A patent/IE66155B1/en not_active IP Right Cessation
- 1990-06-21 NO NO902776A patent/NO178374C/no not_active IP Right Cessation
- 1990-06-21 PT PT94449A patent/PT94449B/pt not_active IP Right Cessation
- 1990-06-22 CN CN90103127A patent/CN1027759C/zh not_active Expired - Fee Related
- 1990-06-22 JP JP2163002A patent/JP2879951B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
DE69017543T2 (de)	1995-07-06
AU626428B2 (en)	1992-07-30
NO902776L (no)	1990-12-27
CA2019231A1 (en)	1990-12-22
CN1027759C (zh)	1995-03-01
JPH0338591A (ja)	1991-02-19
FI97619C (fi)	1997-01-27
IE902252L (en)	1990-12-22
FI903104A0 (fi)	1990-06-20
ZA904715B (en)	1991-04-24
HUT54695A (en)	1991-03-28
JP2879951B2 (ja)	1999-04-05
DE69017543D1 (de)	1995-04-13
EP0409676A1 (de)	1991-01-23
PT94449A (pt)	1991-02-08
DK0409676T3 (da)	1995-03-27
AU5758490A (en)	1991-01-03
NO902776D0 (no)	1990-06-21
FI97619B (fi)	1996-10-15
CA2019231C (en)	2000-07-11
HU210569B (en)	1995-05-29
PT94449B (pt)	1997-02-28
KR0139529B1 (ko)	1998-07-01
CN1048389A (zh)	1991-01-09
ATE119535T1 (de)	1995-03-15
HU903933D0 (en)	1990-11-28
IE66155B1 (en)	1995-12-13
IE902252A1 (en)	1991-01-16
EP0409676B1 (de)	1995-03-08
ES2072406T3 (es)	1995-07-16
AR247214A1 (es)	1994-11-30
KR910000757A (ko)	1991-01-30
IL94779A (en)	1996-09-12
NZ234136A (en)	1994-04-27
NO178374B (no)	1995-12-04
EP0403713A1 (de)	1990-12-27

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Legal Events

Date	Code	Title	Description
2001-01-29	MM1K	Lapsed by not paying the annual fees	Free format text: LAPSED IN DECEMBER 2000