NO179252C - Fremgangsmåte for rensing av rekombinant protein - Google Patents

Fremgangsmåte for rensing av rekombinant protein

Info

Publication number: NO179252C
Authority: NO; Norway
Prior art keywords: recombinant protein; purifying recombinant; prokaryotes; mammalian; purified
Prior art date: 1989-03-15

Application number

NO904927A

Other languages

English (en)

Other versions

NO179252B (no

NO904927L (no

NO904927D0 (no

Inventor

Nicolaas Ludovicus Mar Persoon

Robert Willem Van Leen

Original Assignee

Gist Brocades Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-03-15

Filing date

1990-11-13

Publication date

1996-09-04

1990-11-13 Application filed by Gist Brocades Nv filed Critical Gist Brocades Nv

1990-11-13 Publication of NO904927L publication Critical patent/NO904927L/no

1990-11-13 Publication of NO904927D0 publication Critical patent/NO904927D0/no

1996-05-28 Publication of NO179252B publication Critical patent/NO179252B/no

1996-09-04 Publication of NO179252C publication Critical patent/NO179252C/no

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5403—IL-3
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20041—Use of virus, viral particle or viral elements as a vector
- C12N2710/20043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
- C12N2830/002—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination inducible enhancer/promoter combination, e.g. hypoxia, iron, transcription factor
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/15—Vector systems having a special element relevant for transcription chimeric enhancer/promoter combination
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/60—Vector systems having a special element relevant for transcription from viruses
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
- C12N2830/85—Vector systems having a special element relevant for transcription from vertebrates mammalian

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Zoology (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Molecular Biology (AREA)
Public Health (AREA)
Biochemistry (AREA)
Veterinary Medicine (AREA)
Biophysics (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Microbiology (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
Virology (AREA)
Diabetes (AREA)
Immunology (AREA)
Hematology (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

NO904927A 1989-03-15 1990-11-13 Fremgangsmåte for rensing av rekombinant protein NO179252C (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
EP89200660		1989-03-15
EP89201967		1989-07-25
PCT/NL1990/000030 WO1990010705A2 (en)	1989-03-15	1990-03-15	Production and purification of recombinant human interleukin-3 and muteins thereof

Publications (4)

Publication Number	Publication Date
NO904927L NO904927L (no)	1990-11-13
NO904927D0 NO904927D0 (no)	1990-11-13
NO179252B NO179252B (no)	1996-05-28
NO179252C true NO179252C (no)	1996-09-04

Family

ID=26121004

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO904927A NO179252C (no)	1989-03-15	1990-11-13	Fremgangsmåte for rensing av rekombinant protein

Country Status (17)

Country	Link
EP (1)	EP0390252B1 (no)
JP (1)	JPH03504561A (no)
AT (1)	ATE140979T1 (no)
AU (1)	AU633891B2 (no)
CA (1)	CA2028827A1 (no)
DE (1)	DE69027948T2 (no)
DK (1)	DK0390252T3 (no)
ES (1)	ES2092486T3 (no)
FI (1)	FI905593A0 (no)
GR (1)	GR3021140T3 (no)
HU (1)	HUT56134A (no)
IE (1)	IE75344B1 (no)
IL (1)	IL93756A (no)
NO (1)	NO179252C (no)
NZ (1)	NZ232913A (no)
PT (1)	PT93458B (no)
WO (1)	WO1990010705A2 (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5705362A (en) *	1992-05-25	1998-01-06	Gist-Brocades, N.V.	Modified signal sequences
US5437951A (en)	1992-09-03	1995-08-01	The United States Of America As Represented By The Department Of Health And Human Services	Self-assembling recombinant papillomavirus capsid proteins
US5463029A (en) *	1992-11-23	1995-10-31	Immunex Corporation	Purification of fusion proteins comprising GM-CSF and IL-3
EP1361273A3 (en) *	1992-11-24	2004-02-11	G.D. Searle & Co.	Interleukin-3 (IL-3) multiple mutation polypeptides
US5738849A (en) *	1992-11-24	1998-04-14	G. D. Searle & Co.	Interleukin-3 (IL-3) variant fusion proteins, their recombinant production, and therapeutic compositions comprising them
US8062642B1 (en)	1993-03-09	2011-11-22	University Of Rochester	Production of papillomavirus capsid protein and virus-like particles
US6153201A (en) *	1993-03-09	2000-11-28	University Of Rochester	Oral immunization with papillomavirus virus-like particles
ATE492289T1 (de) *	1993-03-09	2011-01-15	Univ Rochester	Herstellung von menschlichen papillomavirus hbv- 11 kapsidprotein l1 und virus-ähnliche partikeln
US5501962A (en) *	1993-06-21	1996-03-26	G. D. Searle & Co.	Interleuken-3 (IL-3) human/murine hybrid polypeptides and recombinant production of the same
US6017523A (en) *	1995-06-06	2000-01-25	G.D. Searle & Co.	Therapeutic methods employing mutant human interleukin-3 (IL-3) polypeptides
AU2866599A (en) *	1998-02-17	1999-08-30	Hyseq, Inc.	A novel interleukin-3 and uses thereof
US20020039584A1 (en)	1998-02-20	2002-04-04	Medigene Ag	Papilloma virus capsomere vaccine formulations and methods of use
US7494658B2 (en)	1998-02-20	2009-02-24	Medigene Ag	Papilloma virus truncated L1 protein and fusion protein constructs
US7182947B2 (en)	1998-02-20	2007-02-27	Medigene Ag	Papillomavirus truncated L1 protein and fusion protein constructs
CA2229955C (en)	1998-02-20	2003-12-09	Medigene Gmbh	Papilloma virus capsomere vaccine formulations and methods of use
US6926897B1 (en)	1998-03-24	2005-08-09	Medigene Aktiengesellschaft	Medicament for the avoidance or treatment of papillomavirus-specific tumour

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4419446A (en) *	1980-12-31	1983-12-06	The United States Of America As Represented By The Department Of Health And Human Services	Recombinant DNA process utilizing a papilloma virus DNA as a vector
GR871029B (en) *	1986-07-14	1987-11-02	Genetics Inst	Novel osteoinductive factors
NZ222939A (en) *	1986-12-16	1991-03-26	Gist Brocades Nv	Human interleukin-3, production using genetic engineering methods, antibodies to human interleukin-3 and screening of dna library with 3' untranslated region
AU1496688A (en) *	1987-01-20	1988-08-10	Immunex Corporation	Human interleukin-3 proteins

1990
- 1990-03-14 NZ NZ232913A patent/NZ232913A/en unknown
- 1990-03-15 FI FI905593A patent/FI905593A0/fi not_active IP Right Cessation
- 1990-03-15 AU AU52644/90A patent/AU633891B2/en not_active Ceased
- 1990-03-15 DE DE69027948T patent/DE69027948T2/de not_active Expired - Fee Related
- 1990-03-15 CA CA002028827A patent/CA2028827A1/en not_active Abandoned
- 1990-03-15 IL IL93756A patent/IL93756A/xx not_active IP Right Cessation
- 1990-03-15 AT AT90200624T patent/ATE140979T1/de not_active IP Right Cessation
- 1990-03-15 PT PT93458A patent/PT93458B/pt active IP Right Grant
- 1990-03-15 IE IE93790A patent/IE75344B1/en not_active IP Right Cessation
- 1990-03-15 JP JP2504691A patent/JPH03504561A/ja active Pending
- 1990-03-15 DK DK90200624.6T patent/DK0390252T3/da active
- 1990-03-15 ES ES90200624T patent/ES2092486T3/es not_active Expired - Lifetime
- 1990-03-15 HU HU902850A patent/HUT56134A/hu unknown
- 1990-03-15 EP EP90200624A patent/EP0390252B1/en not_active Expired - Lifetime
- 1990-03-15 WO PCT/NL1990/000030 patent/WO1990010705A2/en not_active Ceased
- 1990-11-13 NO NO904927A patent/NO179252C/no unknown
1996
- 1996-09-25 GR GR960402506T patent/GR3021140T3/el unknown

Also Published As

Publication number	Publication date
JPH03504561A (ja)	1991-10-09
DE69027948D1 (de)	1996-09-05
ES2092486T3 (es)	1996-12-01
PT93458B (pt)	1997-01-31
IL93756A0 (en)	1990-12-23
EP0390252A3 (en)	1991-06-19
ATE140979T1 (de)	1996-08-15
AU5264490A (en)	1990-10-09
HU902850D0 (en)	1991-02-28
GR3021140T3 (en)	1996-12-31
IE900937L (en)	1990-09-15
AU633891B2 (en)	1993-02-11
FI905593A7 (fi)	1990-11-12
DE69027948T2 (de)	1997-01-30
EP0390252B1 (en)	1996-07-31
WO1990010705A3 (en)	1990-11-01
NZ232913A (en)	1992-08-26
NO179252B (no)	1996-05-28
WO1990010705A2 (en)	1990-09-20
NO904927L (no)	1990-11-13
PT93458A (pt)	1990-11-07
HUT56134A (en)	1991-07-29
IE75344B1 (en)	1997-08-27
FI905593A0 (fi)	1990-11-12
DK0390252T3 (da)	1996-12-09
EP0390252A2 (en)	1990-10-03
CA2028827A1 (en)	1990-09-16
NO904927D0 (no)	1990-11-13
IL93756A (en)	1997-06-10

Publication	Publication Date	Title
NO179252C (no)	1996-09-04	Fremgangsmåte for rensing av rekombinant protein
ES2122955T3 (es)	1999-01-01	Adn que codifica proteinas que se unen a la il-1 humana.
ATE142692T1 (de)	1996-09-15	Herstellung von hämoglobin und analogen davon durch bakterien oder hefen
NO175825C (no)	1994-12-14	DNA molekyl kodende for humant og gibbon IL-3 protein, vektor, celle og fremgangsmåte for fremstilling av et IL-3 protein
DE3650538D1 (de)	1996-08-08	Interleukin-4 protein mit bcgf- und tcgf-aktivität gegenüber menschlichen zellen (menschliches interleukin-4)
EP0145390A3 (en)	1987-01-21	A method for producing non-glycosylated human interleukin-2 protein
FI864654A0 (fi)	1986-11-14	Menetelmä modifioidun ihmisen t-PA-proteiinin valmistamiseksi
AU3143589A (en)	1989-09-21	Human nerve growth factor
ES2108681T3 (es)	1998-01-01	Expresion de la albumina del suero humano en las levaduras metilotroficas.
FI103974B1 (fi)	1999-10-29	Menetelmä proteiinin puhdistamiseksi
DE69126049D1 (de)	1997-06-19	Vektoren und Zusammensetzungen zur Expression von Glykosilationsmutanten des menschlichen Proteins-C
ATE108831T1 (de)	1994-08-15	Rinder-interleukin-1-alpha.
DE3650477D1 (de)	1996-03-14	Produktion von Cystinreste enthaltenden aktiven Proteinen
DE68925044D1 (de)	1996-01-25	Herstellung von Fusionsproteinen oder -polypeptiden
ATE79884T1 (de)	1992-09-15	Reinigung von gm-csf.
ATE110112T1 (de)	1994-09-15	Verfahren und systeme zur herstellung von hiv- antigenen.
EP1010758A3 (en)	2001-12-19	An expression system for producing recombinant human erythropoietin, a method for purifying the secreted human erythropoietin and uses thereof
EP0249854A3 (en)	1988-12-21	Novel polypeptide