NO179583C - Analogifremgangsmåte for fremstilling av terapeutisk aktive 1-(pyridinylalkyl)-1H-indoler - Google Patents

Analogifremgangsmåte for fremstilling av terapeutisk aktive 1-(pyridinylalkyl)-1H-indoler

Info

Publication number: NO179583C
Authority: NO; Norway
Prior art keywords: hydrogen; loweralkyl; pyridinylalkyl; indoles; preparation
Prior art date: 1990-08-13

Application number

NO913140A

Other languages

English (en)

Norwegian (no)

Other versions

NO913140D0 (no

NO913140L (no

NO179583B (no

Inventor

Richard Charles Effland

Larry Davis

Gordon Edward Olsen

Original Assignee

Hoechst Marion Roussel Inc

Hoechst Roussel Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-08-13

Filing date

1991-08-12

Publication date

1996-11-06

1991-08-12 Application filed by Hoechst Marion Roussel Inc, Hoechst Roussel Pharma filed Critical Hoechst Marion Roussel Inc

1991-08-12 Publication of NO913140D0 publication Critical patent/NO913140D0/no

1992-02-14 Publication of NO913140L publication Critical patent/NO913140L/no

1996-07-29 Publication of NO179583B publication Critical patent/NO179583B/no

1996-11-06 Publication of NO179583C publication Critical patent/NO179583C/no

Links

150000002431 hydrogen Chemical class 0.000 abstract 4
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
150000001875 compounds Chemical class 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
150000002367 halogens Chemical class 0.000 abstract 2
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
208000024827 Alzheimer disease Diseases 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
230000006949 cholinergic function Effects 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
230000003247 decreasing effect Effects 0.000 abstract 1
125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
230000007074 memory dysfunction Effects 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
-1 nitro, amino Chemical group 0.000 abstract 1
230000003287 optical effect Effects 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Neurosurgery (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Hospice & Palliative Care (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Psychiatry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Indole Compounds (AREA)
Display Devices Of Pinball Game Machines (AREA)

NO913140A 1990-08-13 1991-08-12 Analogifremgangsmåte for fremstilling av terapeutisk aktive 1-(pyridinylalkyl)-1H-indoler NO179583C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US56657590A	1990-08-13	1990-08-13

Publications (4)

Publication Number	Publication Date
NO913140D0 NO913140D0 (no)	1991-08-12
NO913140L NO913140L (no)	1992-02-14
NO179583B NO179583B (no)	1996-07-29
NO179583C true NO179583C (no)	1996-11-06

Family

ID=24263468

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO913140A NO179583C (no)	1990-08-13	1991-08-12	Analogifremgangsmåte for fremstilling av terapeutisk aktive 1-(pyridinylalkyl)-1H-indoler

Country Status (20)

Country	Link
EP (1)	EP0471296B1 (cs)
JP (1)	JP3057828B2 (cs)
KR (1)	KR100223133B1 (cs)
AT (1)	ATE130002T1 (cs)
AU (1)	AU637249B2 (cs)
CA (1)	CA2048980C (cs)
CS (1)	CS249191A3 (cs)
DE (1)	DE69114404T2 (cs)
DK (1)	DK0471296T3 (cs)
ES (1)	ES2079530T3 (cs)
FI (1)	FI103341B (cs)
GR (1)	GR3018187T3 (cs)
HU (1)	HUT58722A (cs)
IE (1)	IE70596B1 (cs)
IL (1)	IL99168A (cs)
MX (1)	MX9100638A (cs)
NO (1)	NO179583C (cs)
NZ (2)	NZ239328A (cs)
PL (1)	PL291408A1 (cs)
ZA (1)	ZA916341B (cs)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5068234A (en) *	1990-02-26	1991-11-26	Sterling Drug Inc.	3-arylcarbonyl-1-(c-attached-n-heteryl)-1h-indoles
EP0471298B1 (en) *	1990-08-13	1995-11-02	Hoechst-Roussel Pharmaceuticals Incorporated	Carbamoyl-1-(pyridinylalkyl)-1H-indoles, indolines and related analogs
FR2674522B1 (fr) *	1991-03-26	1993-07-16	Lipha	Nouveaux derives de l'indole, procedes de preparation et medicaments les contenant.
WO2003087087A2 (en) *	2002-04-09	2003-10-23	Astex Technology Limited	Heterocyclic compounds and their use as modulators of p38 map kinase

1991
- 1991-08-08 ES ES91113333T patent/ES2079530T3/es not_active Expired - Lifetime
- 1991-08-08 DE DE69114404T patent/DE69114404T2/de not_active Expired - Fee Related
- 1991-08-08 DK DK91113333.8T patent/DK0471296T3/da active
- 1991-08-08 EP EP91113333A patent/EP0471296B1/en not_active Expired - Lifetime
- 1991-08-08 AT AT91113333T patent/ATE130002T1/de not_active IP Right Cessation
- 1991-08-09 NZ NZ239328A patent/NZ239328A/en unknown
- 1991-08-09 NZ NZ260632A patent/NZ260632A/en unknown
- 1991-08-09 FI FI913799A patent/FI103341B/fi active
- 1991-08-12 AU AU81767/91A patent/AU637249B2/en not_active Ceased
- 1991-08-12 MX MX9100638A patent/MX9100638A/es not_active IP Right Cessation
- 1991-08-12 KR KR1019910013849A patent/KR100223133B1/ko not_active Expired - Fee Related
- 1991-08-12 PL PL29140891A patent/PL291408A1/xx unknown
- 1991-08-12 JP JP3201711A patent/JP3057828B2/ja not_active Expired - Fee Related
- 1991-08-12 CS CS912491A patent/CS249191A3/cs unknown
- 1991-08-12 IL IL9916891A patent/IL99168A/en unknown
- 1991-08-12 NO NO913140A patent/NO179583C/no unknown
- 1991-08-12 ZA ZA916341A patent/ZA916341B/xx unknown
- 1991-08-12 HU HU912674A patent/HUT58722A/hu unknown
- 1991-08-12 IE IE285091A patent/IE70596B1/en not_active IP Right Cessation
- 1991-08-12 CA CA002048980A patent/CA2048980C/en not_active Expired - Fee Related
1995
- 1995-11-22 GR GR950403313T patent/GR3018187T3/el unknown

Also Published As

Publication number	Publication date
IL99168A (en)	1995-07-31
ATE130002T1 (de)	1995-11-15
DK0471296T3 (da)	1996-03-11
EP0471296B1 (en)	1995-11-08
AU637249B2 (en)	1993-05-20
CS249191A3 (en)	1992-03-18
ES2079530T3 (es)	1996-01-16
EP0471296A1 (en)	1992-02-19
KR920004379A (ko)	1992-03-27
JP3057828B2 (ja)	2000-07-04
AU8176791A (en)	1992-02-20
CA2048980A1 (en)	1992-02-14
HU912674D0 (en)	1992-01-28
FI913799A7 (fi)	1992-02-14
FI103341B1 (fi)	1999-06-15
NO913140D0 (no)	1991-08-12
DE69114404T2 (de)	1996-05-02
NO913140L (no)	1992-02-14
NZ260632A (en)	1997-06-24
IE70596B1 (en)	1996-12-11
IL99168A0 (en)	1992-07-15
DE69114404D1 (de)	1995-12-14
PL291408A1 (en)	1992-12-28
ZA916341B (en)	1992-04-29
HUT58722A (en)	1992-03-30
NO179583B (no)	1996-07-29
JPH05132481A (ja)	1993-05-28
GR3018187T3 (en)	1996-02-29
FI103341B (fi)	1999-06-15
MX9100638A (es)	1992-04-01
CA2048980C (en)	2003-05-13
FI913799A0 (fi)	1991-08-09
KR100223133B1 (ko)	1999-10-15
IE912850A1 (en)	1992-02-26
NZ239328A (en)	1996-03-26

Publication	Publication Date	Title
NO175980C (no)	1995-01-11	Analogifremgangsmåte for fremstilling av terapeutisk aktive 4- og 6-karbamater av physostigmin og mellomprodukter
FI102067B1 (fi)	1998-10-15	Menetelmä terapeuttisesti käyttökelpoisten 1-(substituoitu pyridinyyliamino)-1H-indol-5-yyli-substituoitujen karbamaattien valmistamiseksi
PT92234A (pt)	1990-05-31	Processo para a preparacao de 1,2,3,4-tetraidro-1,9-acridinodiaminas
NO179583C (no)	1996-11-06	Analogifremgangsmåte for fremstilling av terapeutisk aktive 1-(pyridinylalkyl)-1H-indoler
FI96308C (fi)	1996-06-10	Menetelmä terapeuttisesti käyttökelpoisten 9-aminotetrahydroakridiinien ja niiden johdannaisten valmistamiseksi
NO177053C (no)	1995-07-12	Analogifremgangsmåte for fremstilling av terapeutisk aktive (1,2,3,4-tetrahydro-9-akridinimino)cykloheksankarboksylsyrer
NO173783C (no)	1994-02-02	Analogifremgangsmaate for fremstilling av terapeutisk aktive, kondenserte heterodykliske derivater av 1,2,3,4-tetrahydroakridiner
NO178372C (no)	1996-03-13	Analogifremgangsmåte for fremstilling av terapeutisk aktive karbamoyl-1-(pyrindinylalkyl)-1H-indoler