NO20001557L - Tetrahydrofuranfosfat- og hydroksyestere som prolegemidler for det tilsvarende antifungale middel - Google Patents

Tetrahydrofuranfosfat- og hydroksyestere som prolegemidler for det tilsvarende antifungale middel

Info

Publication number: NO20001557L
Authority: NO; Norway
Prior art keywords: prodrugs; tetrahydrofuran; phosphate; antifungal agent; hydroxy esters
Prior art date: 1997-09-25

Application number

NO20001557A

Other languages

English (en)

Norwegian (no)

Other versions

NO20001557D0 (no

Inventor

Frank Bennett

Viyyoor M Girijavallabhan

Naginbhai M Patel

Anil K Saksena

Ashit Ganguly

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-09-25

Filing date

2000-03-24

Publication date

2000-03-24

2000-03-24 Application filed by Schering Corp filed Critical Schering Corp

2000-03-24 Publication of NO20001557D0 publication Critical patent/NO20001557D0/no

2000-03-24 Publication of NO20001557L publication Critical patent/NO20001557L/no

Links

229940121375 antifungal agent Drugs 0.000 title 1
239000003429 antifungal agent Substances 0.000 title 1
125000002887 hydroxy group Chemical group [H]O* 0.000 title 1
MSZYQCNHWFXSAK-UHFFFAOYSA-N oxolane;phosphoric acid Chemical compound C1CCOC1.OP(O)(O)=O MSZYQCNHWFXSAK-UHFFFAOYSA-N 0.000 title 1
229940002612 prodrug Drugs 0.000 title 1
239000000651 prodrug Substances 0.000 title 1
206010017533 Fungal infection Diseases 0.000 abstract 1
208000031888 Mycoses Diseases 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having three nitrogen atoms as the only ring hetero atoms
- C07F9/6518—Five-membered rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65586—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

NO20001557A 1997-09-25 2000-03-24 Tetrahydrofuranfosfat- og hydroksyestere som prolegemidler for det tilsvarende antifungale middel NO20001557L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US93782797A	1997-09-25	1997-09-25
PCT/US1998/018508 WO1999015522A1 (fr)	1997-09-25	1998-09-22	Phosphate-esters et hydroxy-esters de tetrahydrofurane utilises comme promedicaments pour agent antifongique correspondant

Publications (2)

Publication Number	Publication Date
NO20001557D0 NO20001557D0 (no)	2000-03-24
NO20001557L true NO20001557L (no)	2000-03-24

Family

ID=25470461

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20001557A NO20001557L (no)	1997-09-25	2000-03-24	Tetrahydrofuranfosfat- og hydroksyestere som prolegemidler for det tilsvarende antifungale middel

Country Status (25)

Country	Link
EP (1)	EP1027349B1 (fr)
JP (1)	JP3473949B2 (fr)
KR (1)	KR20010024297A (fr)
CN (1)	CN1125066C (fr)
AR (1)	AR015458A1 (fr)
AT (1)	ATE286502T1 (fr)
AU (1)	AU1698199A (fr)
BR (1)	BR9812671A (fr)
CA (1)	CA2304624C (fr)
CO (1)	CO5011088A1 (fr)
DE (1)	DE69828524T2 (fr)
ES (1)	ES2232974T3 (fr)
HU (1)	HUP0004616A3 (fr)
ID (1)	ID28294A (fr)
IL (1)	IL134469A0 (fr)
MY (1)	MY133775A (fr)
NO (1)	NO20001557L (fr)
NZ (1)	NZ502709A (fr)
PE (1)	PE120799A1 (fr)
PL (1)	PL339488A1 (fr)
PT (1)	PT1027349E (fr)
SK (1)	SK3912000A3 (fr)
TR (1)	TR200000753T2 (fr)
WO (1)	WO1999015522A1 (fr)
ZA (1)	ZA988688B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU1915500A (en)	1998-11-20	2000-06-13	Bristol-Myers Squibb Company	Water soluble prodrugs of azole compounds
CN102906087B (zh) *	2010-05-19	2016-03-23	桑多斯股份公司	制备手性三唑酮的方法
CN111138421A (zh) *	2019-12-26	2020-05-12	上海英诺富成生物科技有限公司	抗真菌水溶性化合物及其制备方法与应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA9410142B (en) *	1993-12-21	1996-05-02	Schering Corp	Tetrahydrofuran antifungals
US5693626A (en) *	1993-12-21	1997-12-02	Schering Corporation	Tetrahydrofuran antifungals

1998
- 1998-09-22 JP JP2000512827A patent/JP3473949B2/ja not_active Expired - Fee Related
- 1998-09-22 AU AU16981/99A patent/AU1698199A/en not_active Abandoned
- 1998-09-22 IL IL13446998A patent/IL134469A0/xx unknown
- 1998-09-22 ID IDW20000551A patent/ID28294A/id unknown
- 1998-09-22 WO PCT/US1998/018508 patent/WO1999015522A1/fr not_active Ceased
- 1998-09-22 PE PE1998000905A patent/PE120799A1/es not_active Application Discontinuation
- 1998-09-22 BR BR9812671-7A patent/BR9812671A/pt not_active IP Right Cessation
- 1998-09-22 NZ NZ502709A patent/NZ502709A/en unknown
- 1998-09-22 PT PT98961721T patent/PT1027349E/pt unknown
- 1998-09-22 AT AT98961721T patent/ATE286502T1/de not_active IP Right Cessation
- 1998-09-22 HU HU0004616A patent/HUP0004616A3/hu unknown
- 1998-09-22 PL PL98339488A patent/PL339488A1/xx unknown
- 1998-09-22 MY MYPI98004343A patent/MY133775A/en unknown
- 1998-09-22 ZA ZA988688A patent/ZA988688B/xx unknown
- 1998-09-22 SK SK391-2000A patent/SK3912000A3/sk unknown
- 1998-09-22 CN CN98809550A patent/CN1125066C/zh not_active Expired - Fee Related
- 1998-09-22 ES ES98961721T patent/ES2232974T3/es not_active Expired - Lifetime
- 1998-09-22 KR KR1020007003196A patent/KR20010024297A/ko not_active Withdrawn
- 1998-09-22 TR TR2000/00753T patent/TR200000753T2/xx unknown
- 1998-09-22 DE DE69828524T patent/DE69828524T2/de not_active Expired - Lifetime
- 1998-09-22 EP EP98961721A patent/EP1027349B1/fr not_active Expired - Lifetime
- 1998-09-22 AR ARP980104741A patent/AR015458A1/es unknown
- 1998-09-22 CA CA002304624A patent/CA2304624C/fr not_active Expired - Fee Related
- 1998-09-23 CO CO98055163A patent/CO5011088A1/es unknown
2000
- 2000-03-24 NO NO20001557A patent/NO20001557L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
HUP0004616A3 (en)	2002-04-29
CN1125066C (zh)	2003-10-22
PE120799A1 (es)	1999-12-01
CA2304624A1 (fr)	1999-04-01
ZA988688B (en)	1999-03-23
EP1027349B1 (fr)	2005-01-05
JP2001517665A (ja)	2001-10-09
ID28294A (id)	2001-05-10
WO1999015522A1 (fr)	1999-04-01
NZ502709A (en)	2001-11-30
DE69828524D1 (de)	2005-02-10
CN1271356A (zh)	2000-10-25
AU1698199A (en)	1999-04-12
NO20001557D0 (no)	2000-03-24
TR200000753T2 (tr)	2001-01-22
EP1027349A1 (fr)	2000-08-16
JP3473949B2 (ja)	2003-12-08
SK3912000A3 (en)	2000-08-14
ES2232974T3 (es)	2005-06-01
CA2304624C (fr)	2007-06-19
HUP0004616A2 (hu)	2002-03-28
IL134469A0 (en)	2001-04-30
PT1027349E (pt)	2005-05-31
PL339488A1 (en)	2000-12-18
ATE286502T1 (de)	2005-01-15
CO5011088A1 (es)	2001-02-28
BR9812671A (pt)	2000-08-22
AR015458A1 (es)	2001-05-02
MY133775A (en)	2007-11-30
DE69828524T2 (de)	2005-12-29
HK1025960A1 (en)	2000-12-01
KR20010024297A (ko)	2001-03-26

Legal Events

Date	Code	Title	Description
2003-06-02	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
TR199700844T1 (xx)	1998-01-21	Pirazolil-Benzoil T�revleri.
TR200103810T2 (tr)	2002-06-21	Mantar öldürücü aktif bileşik kombinasyonları.
DE69428125D1 (de)	2001-10-04	Fungizide tetrahydrofurane
AU5655998A (en)	1998-07-03	Fungicidal active compound combinations
TR199902400T2 (xx)	2000-01-21	Fungusit etkinlik g�steren terkiplerin birle�imleri.
NO20003111L (no)	2000-08-18	Orto-antranilamidderivater som antikoagulanter
TR199801629A2 (xx)	1999-10-21	Fungisidal 2 -metoksibenzofenonlar.
BR0014651A (pt)	2002-06-18	Inibidores de adesão de célula mediada por "alfa" l beta2
WO2000061134A8 (fr)	2001-03-22	Agents antimicrobiens
BR0015177A (pt)	2002-06-18	ésteres de ácido benzóico de oxazolidinonas possuindo um substituinte hidroxiacetilpiperazina
NO981393L (no)	1998-05-25	Guanidinoproteasehemmere
AU660612B2 (en)	1995-07-06	Remedy for asthma
EP0757987A4 (fr)	1997-04-16	Derive de l'acide pyrazolecarboxylique et agent de lutte contre les maladies vegetales
NO20001557L (no)	2000-03-24	Tetrahydrofuranfosfat- og hydroksyestere som prolegemidler for det tilsvarende antifungale middel
AU693682B2 (en)	1998-07-02	Cancerous metastasis inhibitor
UA43329C2 (uk)	2001-12-17	Рідкий пестицидний засіб у вигляді емульсії "масло-у-воді"
AU2083695A (en)	1995-10-17	Anxiolytic agent
EP0666077A4 (fr)	1995-09-06
AR004551A1 (es)	1998-12-16	Compuestos fungicidas (b)
ATE230268T1 (de)	2003-01-15	Fungizid
WO2000069843A3 (fr)	2001-02-15	Derives de 3-uree-benzofurane- et -pyridofurane, substitues par cycloalkyle
TR199901284A2 (xx)	2000-01-21	Ester bile�imleri.
MX9709016A (es)	1998-04-30	2-amino-benzoxazinonas, composiciones que las contienen y uso de las mismas.
EP0862917A4 (fr)	2002-01-09	Composition antifongique
IE42032L (en)	1976-05-09	Fungicide containing a benzimidazole compound