NO20002168L - Method of Preparation of Chiral Nucleoside Analogs - Google Patents

Method of Preparation of Chiral Nucleoside Analogs

Info

Publication number
NO20002168L
NO20002168L NO20002168A NO20002168A NO20002168L NO 20002168 L NO20002168 L NO 20002168L NO 20002168 A NO20002168 A NO 20002168A NO 20002168 A NO20002168 A NO 20002168A NO 20002168 L NO20002168 L NO 20002168L
Authority
NO
Norway
Prior art keywords
preparation
nucleoside analogs
chiral nucleoside
cyclopropylamino
amino
Prior art date
Application number
NO20002168A
Other languages
Norwegian (no)
Other versions
NO20002168D0 (en
Inventor
Martin Francis Jones
Christopher John Wallis
Shiping Xie
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP1997/006379 external-priority patent/WO1999024431A1/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Priority to NO20002168A priority Critical patent/NO20002168L/en
Publication of NO20002168D0 publication Critical patent/NO20002168D0/en
Publication of NO20002168L publication Critical patent/NO20002168L/en

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  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Det er beskrevet en ny fremgangsmåte for fremstilling av chiral nukleosid- analog (1S,4R)-4-[2-amino-6-(cyklopropylamino)-9H purin-9-yl]-2-cyklopenten-1- metanol omfattende omsetning av en forbindelse ifølge formel (II) eller (III), hvori S er hydrogen eller en blokkeringsgruppe, og Y er H eller en aktiveringsgruppe, med 2-amino-6-(cyklopropylamino)purin i nærvær av en katalysator.A new process is described for the preparation of chiral nucleoside analog (1S, 4R) -4- [2-amino-6- (cyclopropylamino) -9H purin-9-yl] -2-cyclopenten-1-methanol comprising reacting a compound of formula (II) or (III), wherein S is hydrogen or a blocking group, and Y is H or an activating group, with 2-amino-6- (cyclopropylamino) purine in the presence of a catalyst.

NO20002168A 1997-11-12 2000-04-27 Method of Preparation of Chiral Nucleoside Analogs NO20002168L (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO20002168A NO20002168L (en) 1997-11-12 2000-04-27 Method of Preparation of Chiral Nucleoside Analogs

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP1997/006379 WO1999024431A1 (en) 1997-11-12 1997-11-12 Process for preparing a chiral nucleoside analogue
NO20002168A NO20002168L (en) 1997-11-12 2000-04-27 Method of Preparation of Chiral Nucleoside Analogs

Publications (2)

Publication Number Publication Date
NO20002168D0 NO20002168D0 (en) 2000-04-27
NO20002168L true NO20002168L (en) 2000-05-11

Family

ID=19911059

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20002168A NO20002168L (en) 1997-11-12 2000-04-27 Method of Preparation of Chiral Nucleoside Analogs

Country Status (1)

Country Link
NO (1) NO20002168L (en)

Also Published As

Publication number Publication date
NO20002168D0 (en) 2000-04-27

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