NO20002315L - Nye 1-aza-2-alkyl-6-aryl-cykloalkanforbindelser, fremgangsmÕte ved deres fremstilling og farmasøytiske sammensetninger inneholdende dem - Google Patents

Nye 1-aza-2-alkyl-6-aryl-cykloalkanforbindelser, fremgangsmÕte ved deres fremstilling og farmasøytiske sammensetninger inneholdende dem

Info

Publication number: NO20002315L
Authority: NO; Norway
Prior art keywords: alkyl; aryl; aza; phenyl; novel
Prior art date: 1999-05-03

Application number

NO20002315A

Other languages

English (en)

Other versions

NO20002315D0 (no

NO315850B1 (no

Inventor

Sylvain Rault

Olivier Renault

Jean Guillon

Patrick Dallemagne

Pierre Renard

Bruno Pfeiffer

Pierre Lestage

Marie-Cecile Lebrun

Original Assignee

Adir

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-05-03

Filing date

2000-05-02

Publication date

2000-11-06

2000-05-02 Application filed by Adir filed Critical Adir

2000-05-02 Publication of NO20002315D0 publication Critical patent/NO20002315D0/no

2000-11-06 Publication of NO20002315L publication Critical patent/NO20002315L/no

2003-11-03 Publication of NO315850B1 publication Critical patent/NO315850B1/no

Links

239000008194 pharmaceutical composition Substances 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 7
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 3
125000003118 aryl group Chemical group 0.000 abstract 3
125000002252 acyl group Chemical group 0.000 abstract 2
125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 2
LHWIOVMOEBZHCM-UHFFFAOYSA-N 2-methyl-6-phenylpiperidin-4-one Chemical compound N1C(C)CC(=O)CC1C1=CC=CC=C1 LHWIOVMOEBZHCM-UHFFFAOYSA-N 0.000 abstract 1
BWYQNIHGLLVSBK-UHFFFAOYSA-N 6-methyl-2-phenyl-2,3-dihydro-1h-pyridin-4-one Chemical compound N1C(C)=CC(=O)CC1C1=CC=CC=C1 BWYQNIHGLLVSBK-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
125000001072 heteroaryl group Chemical group 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/38—Halogen atoms or nitro radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/54—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/86—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D223/08—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Psychology (AREA)
Psychiatry (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

NO20002315A 1999-05-03 2000-05-02 Nye 1-aza-2-alkyl-6-aryl-cykloalkanforbindelser, fremgangsmåte ved deres fremstilling og farmasöytiske sammensetninger inneholdende dem NO315850B1 (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9905600A FR2793246B1 (fr)	1999-05-03	1999-05-03	Nouveaux derives de 1-aza-2-alkyl-6-aryl-cycloalcanes, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (3)

Publication Number	Publication Date
NO20002315D0 NO20002315D0 (no)	2000-05-02
NO20002315L true NO20002315L (no)	2000-11-06
NO315850B1 NO315850B1 (no)	2003-11-03

Family

ID=9545153

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20002315A NO315850B1 (no)	1999-05-03	2000-05-02	Nye 1-aza-2-alkyl-6-aryl-cykloalkanforbindelser, fremgangsmåte ved deres fremstilling og farmasöytiske sammensetninger inneholdende dem

Country Status (23)

Country	Link
US (2)	US6323222B1 (no)
EP (1)	EP1050530B1 (no)
JP (1)	JP3224376B2 (no)
KR (1)	KR100438086B1 (no)
CN (1)	CN1145612C (no)
AT (1)	ATE252558T1 (no)
AU (1)	AU763685B2 (no)
BR (1)	BR0002076A (no)
CA (1)	CA2308783C (no)
DE (1)	DE60006029T2 (no)
DK (1)	DK1050530T3 (no)
EA (1)	EA002620B1 (no)
ES (1)	ES2209777T3 (no)
FR (1)	FR2793246B1 (no)
HU (1)	HUP0001727A2 (no)
MX (1)	MXPA00004157A (no)
NO (1)	NO315850B1 (no)
NZ (1)	NZ504299A (no)
PL (1)	PL339966A1 (no)
PT (1)	PT1050530E (no)
SE (1)	SE1050530T5 (no)
SI (1)	SI1050530T1 (no)
ZA (1)	ZA200002151B (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2793246B1 (fr) *	1999-05-03	2001-06-29	Adir	Nouveaux derives de 1-aza-2-alkyl-6-aryl-cycloalcanes, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2846654A1 (fr) *	2002-11-05	2004-05-07	Servier Lab	Nouveaux derives de la 2,3-dihydro-4(1h)-pyridinone, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
DE602006019103D1 (de) *	2005-08-12	2011-02-03	Hoffmann La Roche	Fluorsubstituierte 2-oxo-azepan-derivate
WO2010072599A1 (en) *	2008-12-23	2010-07-01	F. Hoffmann-La Roche Ag	Dihydropyridone ureas as p2x7 modulators
US8153808B2 (en) *	2008-12-23	2012-04-10	Roche Palo Alto Llc	Dihydropyridone amides as P2X7 modulators
US12612379B2 (en)	2021-11-30	2026-04-28	Vertex Pharmaceuticals Incorporated	Inhibitors of APOL1 and methods of using same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2013761A1 (en) *	1970-03-21	1971-10-07	Farbwerke Hoechst AG, vorm. Meister Lucius & Brüning, 6000 Frankfurt	4-azacycloalk-2-enone prepn
US4529732A (en) *	1983-03-14	1985-07-16	Pfizer Inc.	2-[2-Hydroxy-4-(substituted)phenyl]piperidines
DE3414830A1 (de) *	1984-04-19	1985-10-31	Hoechst Ag, 6230 Frankfurt	Verfahren und zwischenprodukte zur herstellung von (e)- und (z)-4-methoxy-2,2'-bipyridyl-6-aldoximen und ihre verwendung als arzneimittel
FR2793246B1 (fr) *	1999-05-03	2001-06-29	Adir	Nouveaux derives de 1-aza-2-alkyl-6-aryl-cycloalcanes, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

1999
- 1999-05-03 FR FR9905600A patent/FR2793246B1/fr not_active Expired - Fee Related
2000
- 2000-04-27 JP JP2000127382A patent/JP3224376B2/ja not_active Expired - Fee Related
- 2000-04-27 EA EA200000373A patent/EA002620B1/ru not_active IP Right Cessation
- 2000-04-28 PL PL00339966A patent/PL339966A1/xx not_active Application Discontinuation
- 2000-04-28 MX MXPA00004157A patent/MXPA00004157A/es active IP Right Grant
- 2000-04-30 CN CNB001181580A patent/CN1145612C/zh not_active Expired - Fee Related
- 2000-05-02 NZ NZ504299A patent/NZ504299A/xx unknown
- 2000-05-02 PT PT00401199T patent/PT1050530E/pt unknown
- 2000-05-02 EP EP00401199A patent/EP1050530B1/fr not_active Expired - Lifetime
- 2000-05-02 DK DK00401199T patent/DK1050530T3/da active
- 2000-05-02 NO NO20002315A patent/NO315850B1/no not_active Application Discontinuation
- 2000-05-02 US US09/561,646 patent/US6323222B1/en not_active Expired - Fee Related
- 2000-05-02 SI SI200030240T patent/SI1050530T1/xx unknown
- 2000-05-02 SE SE00401199T patent/SE1050530T5/xx unknown
- 2000-05-02 AT AT00401199T patent/ATE252558T1/de not_active IP Right Cessation
- 2000-05-02 DE DE60006029T patent/DE60006029T2/de not_active Expired - Fee Related
- 2000-05-02 ES ES00401199T patent/ES2209777T3/es not_active Expired - Lifetime
- 2000-05-03 AU AU31324/00A patent/AU763685B2/en not_active Ceased
- 2000-05-03 HU HU0001727A patent/HUP0001727A2/hu unknown
- 2000-05-03 BR BR0002076-1A patent/BR0002076A/pt not_active IP Right Cessation
- 2000-05-03 ZA ZA200002151A patent/ZA200002151B/xx unknown
- 2000-05-03 KR KR10-2000-0023668A patent/KR100438086B1/ko not_active Expired - Fee Related
- 2000-05-03 CA CA002308783A patent/CA2308783C/fr not_active Expired - Fee Related
2001
- 2001-09-26 US US09/964,085 patent/US6451789B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
SE1050530T5 (sv)	2004-03-02
HUP0001727A2 (hu)	2002-04-29
PT1050530E (pt)	2004-02-27
KR100438086B1 (ko)	2004-07-02
EP1050530A1 (fr)	2000-11-08
NO20002315D0 (no)	2000-05-02
HU0001727D0 (en)	2000-07-28
AU763685B2 (en)	2003-07-31
US6451789B1 (en)	2002-09-17
CN1145612C (zh)	2004-04-14
DE60006029D1 (de)	2003-11-27
EA002620B1 (ru)	2002-06-27
KR20010020806A (ko)	2001-03-15
ES2209777T3 (es)	2004-07-01
FR2793246B1 (fr)	2001-06-29
EA200000373A3 (ru)	2001-02-26
MXPA00004157A (es)	2002-03-08
SI1050530T1 (en)	2004-02-29
SE1050530T3 (sv)	2004-02-10
HK1032235A1 (en)	2001-07-13
DK1050530T3 (da)	2004-03-01
JP2000351766A (ja)	2000-12-19
PL339966A1 (en)	2000-11-06
US6323222B1 (en)	2001-11-27
NZ504299A (en)	2001-01-26
FR2793246A1 (fr)	2000-11-10
ZA200002151B (en)	2000-11-07
CA2308783A1 (fr)	2000-11-03
CA2308783C (fr)	2004-10-19
ATE252558T1 (de)	2003-11-15
DE60006029T2 (de)	2004-06-24
AU3132400A (en)	2000-11-09
NO315850B1 (no)	2003-11-03
EA200000373A2 (ru)	2000-12-25
CN1277194A (zh)	2000-12-20
JP3224376B2 (ja)	2001-10-29
US20020042413A1 (en)	2002-04-11
EP1050530B1 (fr)	2003-10-22
BR0002076A (pt)	2001-01-23

Legal Events

Date	Code	Title	Description
2008-01-14	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
TW200738696A (en)	2007-10-16	Isoxazolines for controlling invertebrate pests
DK0870765T3 (da)	2004-02-23	Aminothiazolderivat, lægemiddel indeholdende samme og mellemprodukt til fremstilling af forbindelsen
DE69820248D1 (de)	2004-01-15	Pyrrolidin-derivate die eine phospholipase-a2-hemmende wirkung haben
SE9703377D0 (sv)	1997-09-18	New compounds
DK1031569T3 (da)	2010-05-10	Salt af et 7-isoindolinquinoloncarboxylsyre-derivat, monohydrat deraf og sammensætning, der indeholder dette som aktiv bestanddel
NO20054787D0 (no)	2005-10-18	Indenderivater som farmasotiske midler
NO20013643L (no)	2002-01-28	Fremgangsmåte for fremstilling av optisk aktiv alkohol
NO20002315D0 (no)	2000-05-02	Nye 1-aza-2-alkyl-6-aryl-cykloalkanforbindelser, fremgangsmÕte ved deres fremstilling og farmasøytiske sammensetninger inneholdende dem
NO20082226L (no)	2008-07-01	6-heteroarylpyridoindolonderivater, deres fremstilling og terapeutisk anvendelse derav
EP1357124A4 (en)	2004-02-04	HETEROCYCLIC COMPOUNDS AND COMPOSITIONS IMPROVING CEREBRAL FUNCTIONS CONTAINING THESE AS ACTIVE INGREDIENTS
DK0806413T3 (da)	2002-01-28	2-substituerede viatmin D3-derivater
EP0712398A1 (en)	1996-05-22	BENZOPYRANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
IL106993A (en)	1997-06-10	Benzenalkanoic acid derivatives and pharmaceutical compositions containing them
DE60234024D1 (de)	2009-11-26	Neue retinoidderivate und eine pharmazeutische anti-krebs-zusammensetzung, die diese verbindungen enthält
HU0000308D0 (en)	2000-03-28	New cyano-indole serotonin-reuptake inhibitor compounds, a process for their preparation and pharmaceutical compositions containing them
EA200200682A1 (ru)	2003-02-27	Новые соединения n-бензилпиперазина, способ их получения и фармацевтические композиции, их содержащие
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ATE222583T1 (de)	2002-09-15	Derivate substituierter amidinonaphthylester
NO955071D0 (no)	1995-12-14	abeo-Ergolin-derivater som 5HT1A-ligander
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