NO20002676L - Androgene steroidforbindelser og en fremgangsmÕte for fremstilling og anvendelse av samme - Google Patents

Androgene steroidforbindelser og en fremgangsmÕte for fremstilling og anvendelse av samme

Info

Publication number
NO20002676L
NO20002676L NO20002676A NO20002676A NO20002676L NO 20002676 L NO20002676 L NO 20002676L NO 20002676 A NO20002676 A NO 20002676A NO 20002676 A NO20002676 A NO 20002676A NO 20002676 L NO20002676 L NO 20002676L
Authority
NO
Norway
Prior art keywords
preparation
same
steroid compounds
androgenic steroid
androgenic
Prior art date
Application number
NO20002676A
Other languages
English (en)
Other versions
NO20002676D0 (no
NO317879B1 (no
Inventor
Edgar C Cook
John A Kepler
Yue-Wei Lee
Mansukh C Wani
Original Assignee
Res Triangle Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Res Triangle Inst filed Critical Res Triangle Inst
Publication of NO20002676L publication Critical patent/NO20002676L/no
Publication of NO20002676D0 publication Critical patent/NO20002676D0/no
Publication of NO317879B1 publication Critical patent/NO317879B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/06—Anabolic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051—Estrane derivatives
    • C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
    • C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C07J1/0077—Ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Neurology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO20002676A 1997-11-26 2000-05-25 Androgene steroidforbindelser,fremgangsmate for fremstilling av samme,farmasoytisk innbefattende samme og anvendelse av samme for fremstilling av medikament NO317879B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/979,369 US5952319A (en) 1997-11-26 1997-11-26 Androgenic steroid compounds and a method of making and using the same
PCT/US1998/024527 WO1999026962A1 (en) 1997-11-26 1998-11-23 Androgenic steroid compounds and a method of making and using the same

Publications (3)

Publication Number Publication Date
NO20002676L true NO20002676L (no) 2000-05-25
NO20002676D0 NO20002676D0 (no) 2000-05-25
NO317879B1 NO317879B1 (no) 2004-12-27

Family

ID=25526867

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20002676A NO317879B1 (no) 1997-11-26 2000-05-25 Androgene steroidforbindelser,fremgangsmate for fremstilling av samme,farmasoytisk innbefattende samme og anvendelse av samme for fremstilling av medikament

Country Status (11)

Country Link
US (4) US5952319A (no)
EP (1) EP1042352B1 (no)
JP (1) JP2001524487A (no)
KR (1) KR100577129B1 (no)
CN (1) CN1257181C (no)
AT (1) ATE368050T1 (no)
AU (1) AU750663B2 (no)
CA (1) CA2311448A1 (no)
DE (1) DE69838146D1 (no)
NO (1) NO317879B1 (no)
WO (1) WO1999026962A1 (no)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6828415B2 (en) * 1993-02-19 2004-12-07 Zentaris Gmbh Oligopeptide lyophilisate, their preparation and use
US5952319A (en) * 1997-11-26 1999-09-14 Research Triangle Institute Androgenic steroid compounds and a method of making and using the same
CN1250563C (zh) * 1999-05-04 2006-04-12 斯特拉坎有限公司 雄激素糖苷及其产生雄性征的活性
US6740645B1 (en) * 1999-09-03 2004-05-25 Research Triangle Institute 17β-acyl-17α-propynyl-11β-(cyclic amino) aryl steroids and their derivatives having antagonist hormonal properties
EP1272196B1 (en) 2000-03-31 2006-08-02 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Methods of making the 4-n-butylcyclohexanoic and the undecanoic acid esters of (7 alpha,11 beta)-dimethyl-17 beta-hydroxy-4-estren-3-one and their medical use
US20030069215A1 (en) * 2001-03-30 2003-04-10 The Government Of The United States Of America, Methods of making and using 7a,11b-dimethyl-17b-hydroxy-4-estren-3-one 17b-trans-4-n-butylcyclohexane carboxylate and 7a,11b-dimethyl-17b-hydroxyestr-4-en-3-one 17-undecanoate
WO2001091744A1 (en) * 2000-05-26 2001-12-06 Harry Fisch Methods of treating androgen deficiency in men using selective antiestrogens
GB0025221D0 (en) * 2000-10-14 2000-11-29 Astrazeneca Ab New process
EP1343804A1 (en) * 2000-12-15 2003-09-17 Akzo Nobel N.V. 14(15)-unsaturated 15- and/or 16- substituted androgens with mixed androgen-progestational profile
DE10104327A1 (de) 2001-01-24 2002-07-25 Schering Ag 11beta-Halogensteroide, deren Herstellung und Verwendung zur Herstellung von Arzneimitteln sowie 11beta-Halogensteroide enthaltende pharmazeutische Präparate
EP1429779A2 (en) * 2001-09-21 2004-06-23 Merck & Co., Inc. Androstanes as androgen receptor modulators
DE10234525A1 (de) * 2002-07-25 2004-02-05 Schering Ag Zusammensetzung, enthaltend ein androgenes 11ß-Halogensteroid und ein Gestagen sowie männliches Kontrazeptivum auf Basis dieser Zusammensetzung
US20040010138A1 (en) * 2002-03-21 2004-01-15 Schering Ag Process for the production of 7alpha-methyl steroids
PL373808A1 (en) 2002-07-24 2005-09-19 Schering Aktiengesellschaft Microbiological method for the production of 7 alpha-substituted 11 alpha-hydroxysteroids
DE10233723A1 (de) * 2002-07-24 2004-02-12 Schering Ag Mikrobiologische Verfahren zur Herstellung von 7α-substituierten 11α-Hydroxysteroiden, daraus herstellbare 7α,17α-substituierte 11β-Halogensteroide, deren Herstellungsverfahren und Verwendung sowie pharmazeutische Präparate, die diese Verbindungen enthalten, sowie daraus herstellbare 7α-substituierte Estra-1,3,5(10)-triene
EP1524983B1 (de) * 2002-07-25 2008-01-02 Bayer Schering Pharma Aktiengesellschaft Zusammensetzung, enthaltend ein androgenes 11-b-halogensteroid und ein gestagen sowie m nnliches kontrazeptivum auf basis dieser zusammensetzung
EP2298315A1 (en) 2002-08-28 2011-03-23 Harbor BioSciences, Inc. Therapeutic treatment methods
US8445469B2 (en) * 2004-12-30 2013-05-21 Bayer Intellectual Property Gmbh 18-methyl-19-nor-17-pregn-4-ene-21,17-carbolactones, as well as pharmaceutical preparations that contain the latter
DE602006005901D1 (de) * 2005-02-04 2009-05-07 Us Gov Health & Human Serv NANDROLON-17ß-CARBONATE
US11072632B2 (en) * 2011-03-25 2021-07-27 UNIVERSITé LAVAL Inhibitors of 17β-HSD1, 17β-HSD3 and 17β-HSD10
US20230227492A1 (en) * 2020-06-11 2023-07-20 The Usa As Represented By The Secretary, Department Of Health And Human Services Monomeric and oligomeric compound embodiments as contraceptives and therapies and methods of making and using the same

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB912036A (en) * 1960-06-23 1962-12-05 British Drug Houses Ltd 11-methylene-5ª--steroids
GB912037A (en) * 1960-06-27 1962-12-05 British Drug Houses Ltd 11-methylene steroids
GB912038A (en) * 1960-06-30 1962-12-05 British Drug Houses Ltd 11ª--methyl-5ª--steroids
US3846456A (en) * 1965-04-07 1974-11-05 Upjohn Co Organic compounds
US3325520A (en) * 1965-12-08 1967-06-13 Searle & Co (optionally 17-hydrocarbon-substituted) 11, 13beta-dialkylgon-4-en-3-ones and esters corresponding
US3652606A (en) * 1970-08-07 1972-03-28 Searle & Co 3-oxygenated 11beta-methylestr-4-en-17beta-ol and esters thereof
FI54128C (fi) * 1972-12-09 1978-10-10 Akzo Nv Foerfarande foer framstaellning av nya 11,11-alkylidensteroider ur oestran- och 19-norpregnanserien med foerbaettrad hormonell verkan
US4412993A (en) * 1980-01-25 1983-11-01 The Upjohn Company Method of treating pseudopregnancy, galactorrhea and mastitis in mammals
DE3909770A1 (de) * 1989-03-21 1990-09-27 Schering Ag Verfahren zur herstellung von 3-desoxy-4-en-steroiden
AU3257993A (en) * 1991-12-22 1993-07-28 Schering Aktiengesellschaft 3-methylsulphonylhydrazono and 3-oxyimino steroids, a method of preparing them, pharmaceutical preparations containing them and their use in the preparation of drugs
US5733565A (en) * 1996-02-23 1998-03-31 The Population Council, Center For Biomedical Research Male contraceptive implant
US5952319A (en) * 1997-11-26 1999-09-14 Research Triangle Institute Androgenic steroid compounds and a method of making and using the same
US20030069215A1 (en) 2001-03-30 2003-04-10 The Government Of The United States Of America, Methods of making and using 7a,11b-dimethyl-17b-hydroxy-4-estren-3-one 17b-trans-4-n-butylcyclohexane carboxylate and 7a,11b-dimethyl-17b-hydroxyestr-4-en-3-one 17-undecanoate
EP1272196B1 (en) 2000-03-31 2006-08-02 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Methods of making the 4-n-butylcyclohexanoic and the undecanoic acid esters of (7 alpha,11 beta)-dimethyl-17 beta-hydroxy-4-estren-3-one and their medical use

Also Published As

Publication number Publication date
US20040097477A1 (en) 2004-05-20
KR100577129B1 (ko) 2006-05-09
AU1589199A (en) 1999-06-15
AU750663B2 (en) 2002-07-25
CA2311448A1 (en) 1999-06-03
US20020103177A1 (en) 2002-08-01
CN1257181C (zh) 2006-05-24
WO1999026962A1 (en) 1999-06-03
EP1042352A4 (en) 2004-12-22
NO20002676D0 (no) 2000-05-25
US6670352B2 (en) 2003-12-30
JP2001524487A (ja) 2001-12-04
CN1283200A (zh) 2001-02-07
US6864248B2 (en) 2005-03-08
US20020002156A1 (en) 2002-01-03
DE69838146D1 (de) 2007-09-06
EP1042352B1 (en) 2007-07-25
KR20010032449A (ko) 2001-04-25
ATE368050T1 (de) 2007-08-15
EP1042352A1 (en) 2000-10-11
NO317879B1 (no) 2004-12-27
US6369047B2 (en) 2002-04-09
US5952319A (en) 1999-09-14

Similar Documents

Publication Publication Date Title
NO20002676D0 (no) Androgene steroidforbindelser og en fremgangsmÕte for fremstilling og anvendelse av samme
TR200800474T2 (tr) Florfenikole aracı maddelerin hazırlanmasına ilişkin işlem.
GB9822376D0 (en) Stabilizer compounds
MX9603050A (es) Derivados de la 1-h-3-aril-pirrolidin-2,4-diona como agentes pesticidas.
AU6613896A (en) Chemical compounds
MY120090A (en) Chemical compounds.
KR100263496B1 (ko) 탁솔 유도체 및 이의 제조방법
MY138525A (en) Substituted acid derivatives useful as antidiabetic and antiobesity agents and method
AU5242000A (en) Nematicidal trifluorobutenes
BG103310A (en) Benzonaphthyridins as bronchial therapeutical means
AU4387296A (en) Diastereomerically pure 3-oxo and 3-thioxo-4-aza-androstan derivatives and the use thereof as antiandrogens
WO1995018821A3 (en) Novel antiandrogenic agents and related pharmaceutical compositions and methods of use
NO981393L (no) Guanidinoproteasehemmere
YU49276B (sh) Postupak za dobijanje olanzapina
NO990914L (no) Amorfe benzotiofener, fremgangsmÕter for fremstilling og fremgangsmÕter for anvendelse
BG105766A (en) New process for preparing pesticidal intermediates
IN187760B (no)
BG106002A (en) Process for preparing pesticidal intermediates
MX9700179A (es) Derivados de triazol y su utilizacion.
IE55842B1 (en) Cardiotonic agents
MX207081B (no)
PL343546A1 (en) Processes for preparing intermediates
TW344650B (en) Fungicidal compositions and the process for the preparation thereof
AU6832498A (en) Substituted benzyl oximino compounds
CA2328832A1 (en) Processes for preparing pesticidal intermediates