NO20002696D0 - Nye forbindelser med cGMP-PDE-inhibitoreffekt - Google Patents

Nye forbindelser med cGMP-PDE-inhibitoreffekt

Info

Publication number
NO20002696D0
NO20002696D0 NO20002696A NO20002696A NO20002696D0 NO 20002696 D0 NO20002696 D0 NO 20002696D0 NO 20002696 A NO20002696 A NO 20002696A NO 20002696 A NO20002696 A NO 20002696A NO 20002696 D0 NO20002696 D0 NO 20002696D0
Authority
NO
Norway
Prior art keywords
cgmp
new compounds
pde inhibitor
inhibitor effect
effect
Prior art date
Application number
NO20002696A
Other languages
English (en)
Other versions
NO20002696L (no
Inventor
Masayuki Ohashi
Hidemitsu Nishida
Toshiyuki Shudo
Original Assignee
Mochida Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mochida Pharm Co Ltd filed Critical Mochida Pharm Co Ltd
Publication of NO20002696D0 publication Critical patent/NO20002696D0/no
Publication of NO20002696L publication Critical patent/NO20002696L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/06—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO20002696A 1997-11-28 2000-05-26 Nye forbindelser med cGMP-PDE-inhibitoreffekt NO20002696L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP34416497 1997-11-28
PCT/JP1998/005350 WO1999028319A1 (en) 1997-11-28 1998-11-27 NOVEL COMPOUNDS HAVING cGMP-PDE INHIBITORY EFFECT

Publications (2)

Publication Number Publication Date
NO20002696D0 true NO20002696D0 (no) 2000-05-26
NO20002696L NO20002696L (no) 2000-07-24

Family

ID=18367131

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20002696A NO20002696L (no) 1997-11-28 2000-05-26 Nye forbindelser med cGMP-PDE-inhibitoreffekt

Country Status (14)

Country Link
US (1) US6476021B1 (no)
EP (1) EP1048666A4 (no)
KR (1) KR20010032546A (no)
CN (1) CN1284075A (no)
AU (1) AU746883B2 (no)
BR (1) BR9815070A (no)
CA (1) CA2311947A1 (no)
HU (1) HUP0100083A3 (no)
IL (1) IL136340A0 (no)
MX (1) MXPA00005190A (no)
NO (1) NO20002696L (no)
PL (1) PL340789A1 (no)
WO (1) WO1999028319A1 (no)
ZA (1) ZA9810766B (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6495528B1 (en) 1998-06-23 2002-12-17 Smithkline Beecham Corporation 2-(Purin -9-yl)-tetrahydrofuran-3,4-diol derivatives
WO2000078760A1 (en) * 1999-06-21 2000-12-28 The Biochemical Pharmaceutical Factory Of Zhuhai Sez Process for preparing sildenafil, and troche which comprises sildenafil and apomorphine
DE19954707A1 (de) * 1999-11-13 2001-05-17 Merck Patent Gmbh Imidazolverbindungen als Phosphodiesterase VII-Hemmer
EP1268477B1 (en) * 2000-03-15 2010-04-21 Sanofi-Aventis Deutschland GmbH Substituted beta-carbolines with ikb-kinase inhibiting activity
CA2402549A1 (en) * 2000-03-15 2001-09-20 Aventis Pharma Deutschland Gmbh Substituted beta-carbolines
CN1436080A (zh) 2000-04-19 2003-08-13 利利艾科斯有限公司 环gmp－特异性磷酸二酯酶抑制剂治疗帕金森氏病的用途
US6271228B1 (en) * 2000-04-28 2001-08-07 Pfizer Inc. Blood pressure stabilization during hemodialysis
UA80258C2 (en) * 2001-09-06 2007-09-10 Biogen Inc Methods of treating pulmonary disease
US20050107394A1 (en) * 2001-12-17 2005-05-19 Ardeschir Ghofrani Novel use of selective pde5 inhibitors
GB0202254D0 (en) * 2002-01-31 2002-03-20 Pfizer Ltd Prevention of scarring
US8133903B2 (en) 2003-10-21 2012-03-13 Los Angeles Biomedical Research Institute at Harbor—UCLA Medical Center Methods of use of inhibitors of phosphodiesterases and modulators of nitric oxide, reactive oxygen species, and metalloproteinases in the treatment of peyronie's disease, arteriosclerosis and other fibrotic diseases
US7601856B2 (en) 2006-07-27 2009-10-13 Wyeth Benzofurans as potassium ion channel modulators
US7662831B2 (en) * 2006-07-27 2010-02-16 Wyeth Llc Tetracyclic indoles as potassium channel modulators
WO2017168174A1 (en) 2016-04-02 2017-10-05 N4 Pharma Uk Limited New pharmaceutical forms of sildenafil
CN115872991B (zh) * 2021-09-26 2024-08-23 深圳大学 β-咔伯啉生物碱类化合物及其药用组合物、制备方法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS261338B1 (cs) * 1987-09-17 1989-06-15 Viktor Zikan Způsob přípravy 10-nitro-4-oxo-4H-chino/2,3,4-i,j//1,4/benzoxazinových derivátů
GB9126260D0 (en) * 1991-12-11 1992-02-12 Pfizer Ltd Therapeutic agents
JPH0710843A (ja) * 1993-03-31 1995-01-13 Eisai Co Ltd 含窒素縮合複素環化合物
PH31122A (en) * 1993-03-31 1998-02-23 Eisai Co Ltd Nitrogen-containing fused-heterocycle compounds.
EP0722936B1 (en) * 1994-08-09 2004-05-19 Eisai Co., Ltd. Fused pyridazine compound
GB9423910D0 (en) * 1994-11-26 1995-01-11 Pfizer Ltd Therapeutic agents
JP3713783B2 (ja) * 1995-01-20 2005-11-09 大正製薬株式会社 １Ｈ−ピラゾロ［３，４−ｄ］ピリミジン−４−オン誘導体
KR20000010919A (ko) * 1996-05-31 2000-02-25 모치다 에이 Cgmp­pde 저해작용이 있는 피리도카르바졸 유도체
IL132993A0 (en) * 1997-05-29 2001-03-19 Mochida Pharm Co Ltd Therapeutic agent for erection failure
AU5067098A (en) * 1997-11-26 1999-06-15 Mochida Pharmaceutical Co., Ltd. Pyridocarbazole derivatives with cgmp-pde inhibitory activity

Also Published As

Publication number Publication date
WO1999028319A1 (en) 1999-06-10
US6476021B1 (en) 2002-11-05
PL340789A1 (en) 2001-02-26
HUP0100083A2 (hu) 2001-08-28
HUP0100083A3 (en) 2002-01-28
EP1048666A1 (en) 2000-11-02
BR9815070A (pt) 2000-10-03
CN1284075A (zh) 2001-02-14
AU1261799A (en) 1999-06-16
NO20002696L (no) 2000-07-24
MXPA00005190A (es) 2002-04-24
CA2311947A1 (en) 1999-06-10
KR20010032546A (ko) 2001-04-25
IL136340A0 (en) 2001-05-20
EP1048666A4 (en) 2001-10-31
AU746883B2 (en) 2002-05-02
ZA9810766B (en) 1999-05-25

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application