NO20002849D0 - Sammensetninger og metoder for Õ indusere genekspersjon - Google Patents

Sammensetninger og metoder for Õ indusere genekspersjon

Info

Publication number
NO20002849D0
NO20002849D0 NO20002849A NO20002849A NO20002849D0 NO 20002849 D0 NO20002849 D0 NO 20002849D0 NO 20002849 A NO20002849 A NO 20002849A NO 20002849 A NO20002849 A NO 20002849A NO 20002849 D0 NO20002849 D0 NO 20002849D0
Authority
NO
Norway
Prior art keywords
compositions
methods
gene expression
inducing gene
inducing
Prior art date
Application number
NO20002849A
Other languages
English (en)
Other versions
NO20002849L (no
Inventor
Richard J Gregory
Karen Vincent
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Publication of NO20002849D0 publication Critical patent/NO20002849D0/no
Publication of NO20002849L publication Critical patent/NO20002849L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/71Fusion polypeptide containing domain for protein-protein interaction containing domain for transcriptional activaation, e.g. VP16
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/80Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/022Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
NO20002849A 1997-12-04 2000-06-02 Sammensetninger og metoder for Õ indusere genekspersjon NO20002849L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6754697P 1997-12-04 1997-12-04
US13361298A 1998-08-13 1998-08-13
PCT/US1998/025753 WO1999028469A1 (en) 1997-12-04 1998-12-04 Compositions and methods for inducing gene expression

Publications (2)

Publication Number Publication Date
NO20002849D0 true NO20002849D0 (no) 2000-06-02
NO20002849L NO20002849L (no) 2000-08-02

Family

ID=26747998

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20002849A NO20002849L (no) 1997-12-04 2000-06-02 Sammensetninger og metoder for Õ indusere genekspersjon

Country Status (9)

Country Link
US (3) US6432927B1 (no)
EP (1) EP1034267A1 (no)
JP (2) JP2001525173A (no)
AU (1) AU749467B2 (no)
CA (1) CA2311643C (no)
IL (2) IL136454A0 (no)
NO (1) NO20002849L (no)
NZ (1) NZ504847A (no)
WO (1) WO1999028469A1 (no)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL136454A0 (en) * 1997-12-04 2001-06-14 Genzyme Corp Compositions and methods for inducing gene expression
US6124131A (en) 1998-08-25 2000-09-26 The Johns Hopkins University School Of Medicine Mutant hypoxia inducible factor-1 HIF-1
FR2801319A1 (fr) * 1999-11-18 2001-05-25 Inst Nat Sante Rech Med Construction d'acide nucleique porteuse d'un systeme regulant l'expression d'un gene
CA2400088A1 (en) * 2000-02-22 2001-08-30 Oxford Biomedica (Uk) Limited Differential expression screening method
SE0002551D0 (sv) * 2000-07-06 2000-07-06 Pharmacia & Upjohn Ab Screening methods
US7214770B2 (en) 2000-07-06 2007-05-08 Angiogenetics Sweden Ab Screening Methods
US20020048794A1 (en) * 2000-08-07 2002-04-25 Lorenz Poellinger Mechanism of conditional regulation of the hypoxia-inducible factor-1 by the von Hippel-Lindau tumor suppressor protein
AU2002221542A1 (en) * 2000-11-07 2002-05-21 Max-Delbruck-Centrum Fur Molekulare Medizin Use of heart-specific transcription factors of the basic helix-loop-helix type for treating cardiac power failure
WO2002068627A2 (en) 2001-02-23 2002-09-06 Novartis Ag Vector constucts
GB0107757D0 (en) * 2001-03-28 2001-05-16 Gendaq Ltd Gene regulation II
AU2002365374A1 (en) * 2001-11-28 2003-06-10 Angiogenetics Sweden Ab Regulation of hypoxia-inducible gene expression with antisense inhibitory pas domain protein
CN102552263A (zh) * 2001-12-06 2012-07-11 法布罗根股份有限公司 提高内源性红细胞生成素(epo)的方法
US7527942B2 (en) 2002-02-08 2009-05-05 The Regents Of The University Of California Transcription amplification system for molecular imaging
DE10245926B4 (de) 2002-10-02 2005-04-07 Ab Elektronik Gmbh Bodenpedal mit Drehwinkelsensor
US7371570B2 (en) 2002-11-01 2008-05-13 Cell Genesys, Inc. Cell-specific adenovirus vector comprising EBV-specific promoter
US7144999B2 (en) * 2002-11-23 2006-12-05 Isis Pharmaceuticals, Inc. Modulation of hypoxia-inducible factor 1 alpha expression
US8124582B2 (en) 2002-12-06 2012-02-28 Fibrogen, Inc. Treatment of diabetes
US7618940B2 (en) 2002-12-06 2009-11-17 Fibrogen, Inc. Fat regulation
WO2005001136A1 (en) * 2003-06-04 2005-01-06 Irm Llc Methods and compositions for modulating erythropoietin expression
US8614204B2 (en) * 2003-06-06 2013-12-24 Fibrogen, Inc. Enhanced erythropoiesis and iron metabolism
US7822276B2 (en) * 2005-02-17 2010-10-26 Iris International, Inc. Method and apparatus for analyzing body fluids
AU2006259352A1 (en) 2005-06-15 2006-12-28 Fibrogen, Inc. Use of HIF 1alfa modulators for treatment of cancer
WO2007048004A2 (en) 2005-10-21 2007-04-26 Cornell Research Foundation, Inc. Compounds for enhancing hypoxia inducible factor activity and methods of use
WO2007114612A1 (en) * 2006-03-30 2007-10-11 Lg Electronics Inc. A method and apparatus for decoding/encoding a video signal
US7759306B2 (en) * 2006-05-16 2010-07-20 Simoni Jan S Methods of treating acute blood loss
WO2007146046A2 (en) 2006-06-07 2007-12-21 Genzyme Corporation Gene therapy for amyotrophic lateral sclerosis and other spinal cord disorders
WO2008033304A2 (en) * 2006-09-12 2008-03-20 Genzyme Corporation Compositions for promoting non-leaky collateral vascularization
US20080081354A1 (en) * 2006-10-02 2008-04-03 Cardiac Pacemakers, Inc. Devices, vectors and methods for inducible ischemia cardioprotection
PL2066791T3 (pl) * 2006-10-03 2013-02-28 Genzyme Corp Terapia Genowa do leczenia stwardnienia zanikowego bocznego i innych zaburzeń rdzenia kręgowego
US9145453B2 (en) * 2007-09-28 2015-09-29 Sdg, Inc. Orally bioavailable lipid-based constructs
US8962015B2 (en) * 2007-09-28 2015-02-24 Sdg, Inc. Orally bioavailable lipid-based constructs
US8846053B2 (en) 2008-09-26 2014-09-30 Sdg, Inc. Orally bioavailable lipid-based constructs
JP5879256B2 (ja) 2009-05-02 2016-03-08 ジェンザイム・コーポレーション 神経変性障害のための遺伝子治療
US20100310530A1 (en) * 2009-05-21 2010-12-09 Stemcyte Inc. Cell Therapy for Brain Tissue Damage
CN107556389B (zh) 2012-02-02 2021-10-26 陶氏益农公司 植物反式激活互作基序及其用途

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991019784A1 (en) 1990-06-13 1991-12-26 The Trustees Of Princeton University A Lac REPRESSOR-HSV VP16 CHIMERIC TRANSCRIPTIONAL ACTIVATOR PROTEIN SYSTEM FUNCTIONING IN TRANSFECTED MAMMALIAN CELLS
CA2098849C (en) * 1990-12-20 2007-07-10 Dana-Farber Cancer Institute Control of gene expression by ionizing radiation
US5962427A (en) * 1994-02-18 1999-10-05 The Regent Of The University Of Michigan In vivo gene transfer methods for wound healing
US5834306A (en) * 1994-12-23 1998-11-10 Sri International Tissue specific hypoxia regulated therapeutic constructs
WO1996026742A1 (en) * 1995-02-28 1996-09-06 The Regents Of The University Of California Gene transfer-mediated angiogenesis therapy
US5792453A (en) * 1995-02-28 1998-08-11 The Regents Of The University Of California Gene transfer-mediated angiogenesis therapy
US5707618A (en) 1995-03-24 1998-01-13 Genzyme Corporation Adenovirus vectors for gene therapy
US5882914A (en) * 1995-06-06 1999-03-16 The Johns Hopkins University School Of Medicine Nucleic acids encoding the hypoxia inducible factor-1
US6306649B1 (en) * 1995-06-27 2001-10-23 Ariad Gene Therapeutics, Inc. Heterologous transcription factors
US6121246A (en) * 1995-10-20 2000-09-19 St. Elizabeth's Medical Center Of Boston, Inc. Method for treating ischemic tissue
US6133027A (en) * 1996-08-07 2000-10-17 City Of Hope Inducible expression system
US5695963A (en) * 1997-01-17 1997-12-09 Board Of Regents, The University Of Texas System Endothelial PAS domain protein
EP0990042A1 (en) 1997-06-10 2000-04-05 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Regulatory sequences involved in hypoxia regulated gene expression and uses thereof
US6087166A (en) * 1997-07-03 2000-07-11 Basf Aktiengesellschaft Transcriptional activators with graded transactivation potential
IL136454A0 (en) * 1997-12-04 2001-06-14 Genzyme Corp Compositions and methods for inducing gene expression
US6124131A (en) * 1998-08-25 2000-09-26 The Johns Hopkins University School Of Medicine Mutant hypoxia inducible factor-1 HIF-1

Also Published As

Publication number Publication date
IL136454A (en) 2010-06-16
CA2311643A1 (en) 1999-06-10
AU1626899A (en) 1999-06-16
JP2007195555A (ja) 2007-08-09
NO20002849L (no) 2000-08-02
IL136454A0 (en) 2001-06-14
US20060127361A1 (en) 2006-06-15
JP2001525173A (ja) 2001-12-11
US20030018007A1 (en) 2003-01-23
EP1034267A1 (en) 2000-09-13
CA2311643C (en) 2009-04-07
US7053062B2 (en) 2006-05-30
AU749467B2 (en) 2002-06-27
WO1999028469A1 (en) 1999-06-10
US6432927B1 (en) 2002-08-13
NZ504847A (en) 2003-02-28

Similar Documents

Publication Publication Date Title
NO20002849D0 (no) Sammensetninger og metoder for Õ indusere genekspersjon
NO2008012I2 (no) Dabigatran-eteksilat og salter derav - spesielt dabigatran-eteksilat-mesylat
DK0813873T3 (da) Farmaceutisk sammensætning omfattende mirtazapin og en eller flere selektive serotingenoptagelseshæmmere
NO20003096D0 (no) Sammensetninger og fremgangsmÕter for behandling av ADD
NO990296D0 (no) HPPD-genet og inhibitorer
DK1112174T3 (da) Isosorbidholdige polyestere og fremgangsmåder til fremstiling heraf
IS5158A (is) Genaraðgreinir og aðferðir
IS5525A (is) Innúðabúnaður og aðferð
NO20001323D0 (no) Dipeptid-apoptose inhibitorer og deres anvendelse
DK0971735T3 (da) Fremgangsmåder og præparater til behandling af inflammatorisk tarmsygdom
NO996578D0 (no) Urokinase-inhibitorer
DK0958287T3 (da) Sulfamidmetalloprotease-inhibitorer
NO20001554L (no) FremgangsmÕter og mellomprodukter nyttige for Õ fremstille antifolater
PT956294E (pt) Inibidores da trombina
DK0977812T3 (da) Asfaltsammensætninger og fremgangsmåder til fremstilling deraf
DK0991666T3 (da) Alfa-1-antitrypsin-præparat og fremgangsmåde til fremstilling heraf
PT869121E (pt) Derivados de propanolamina hipolipidemicos
PT948483E (pt) Inibidores da farnesil-transferase
DK1083934T3 (da) Genterapifremgangsmåder
NO992665D0 (no) Sammensetninger og fremgangsmÕter for Õ administrere pneumokokkisk DNA
DE59803086D1 (de) Elektrolyseapparat
NO970870D0 (no) Mellomprodukter for dinukleotid og oligonukleotid analoger
NO20003268L (no) Hyperhydrert kitikolin, fremgangsmÕte og anvendelse
ITBZ980001V0 (it) Guarnitura per mobili
DE59809195D1 (de) Gebläsebrenner

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application