NO20002904D0 - (E)-3-[1-N-butyl-5-[2-(2-karboksylfenyl)metoksy-4-klorfenyl]- 1H-pyrazol-4-yl]-2-[(5-metoksy-2,3-dihydrobenzofuran-6-yl)methyl]- prop-2-ensyre monoagrininsalt - Google Patents

(E)-3-[1-N-butyl-5-[2-(2-karboksylfenyl)metoksy-4-klorfenyl]- 1H-pyrazol-4-yl]-2-[(5-metoksy-2,3-dihydrobenzofuran-6-yl)methyl]- prop-2-ensyre monoagrininsalt

Info

Publication number: NO20002904D0
Authority: NO; Norway
Prior art keywords: methoxy; monoagrinin; carboxylphenyl; dihydrobenzofuran; pyrazol
Prior art date: 1997-12-08

Application number

NO20002904A

Other languages

English (en)

Other versions

NO20002904L (no

Inventor

Joseph Robert Flisak

Albert Stephen Kearney

Nagesh Palepu

Cherng-Yih Perng

Original Assignee

Smithkline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-12-08

Filing date

2000-06-07

Publication date

2000-06-07

2000-06-07 Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp

2000-06-07 Publication of NO20002904L publication Critical patent/NO20002904L/no

2000-06-07 Publication of NO20002904D0 publication Critical patent/NO20002904D0/no

Links

QVEGXHOZQYEMHS-BUVRLJJBSA-N 2-[[2-[2-butyl-4-[(e)-2-carboxy-3-(5-methoxy-2,3-dihydro-1-benzofuran-6-yl)prop-1-enyl]pyrazol-3-yl]-5-chlorophenoxy]methyl]benzoic acid Chemical compound CCCCN1N=CC(\C=C(/CC=2C(=CC=3CCOC=3C=2)OC)C(O)=O)=C1C1=CC=C(Cl)C=C1OCC1=CC=CC=C1C(O)=O QVEGXHOZQYEMHS-BUVRLJJBSA-N 0.000 title 1
150000003839 salts Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/06—Anti-spasmodics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Diabetes (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Emergency Medicine (AREA)
Vascular Medicine (AREA)
Endocrinology (AREA)
Hematology (AREA)
Obesity (AREA)
Pulmonology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

NO20002904A 1997-12-08 2000-06-07 (E)-3-[1-N-butyl-5-[2-(2-karboksylfenyl)metoksy-4-klorfenyl]- 1H-pyrazol-4-yl]-2-[(5-metoksy-2,3-dihydrobenzofuran-6-yl)methyl]- prop-2-ensyre monoagrininsalt NO20002904D0 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US6773297P	1997-12-08	1997-12-08
PCT/US1998/025903 WO1999029685A1 (en)	1997-12-08	1998-12-07	(e)-3-[1-n-butyl- 5-[2-(2-carboxyphenyl)methoxy- 4-chlorophenyl]-1h- pyrazol-4-yl]-2-[(5- methoxy-2,3- dihydrobenzofuran-6-yl)methyl]- prop-2-enoic acid monoargininyl salt

Publications (2)

Publication Number	Publication Date
NO20002904L NO20002904L (no)	2000-06-07
NO20002904D0 true NO20002904D0 (no)	2000-06-07

Family

ID=22078027

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20002904A NO20002904D0 (no)	1997-12-08	2000-06-07	(E)-3-[1-N-butyl-5-[2-(2-karboksylfenyl)metoksy-4-klorfenyl]- 1H-pyrazol-4-yl]-2-[(5-metoksy-2,3-dihydrobenzofuran-6-yl)methyl]- prop-2-ensyre monoagrininsalt

Country Status (24)

Country	Link
US (1)	US6300359B1 (no)
EP (1)	EP1037888B1 (no)
JP (1)	JP2001525405A (no)
KR (1)	KR20010040292A (no)
CN (1)	CN1281447A (no)
AR (1)	AR017426A1 (no)
AT (1)	ATE223404T1 (no)
AU (1)	AU747108B2 (no)
BR (1)	BR9813409A (no)
CA (1)	CA2312965A1 (no)
CO (1)	CO5021171A1 (no)
DE (1)	DE69807745T2 (no)
DK (1)	DK1037888T3 (no)
ES (1)	ES2182383T3 (no)
HU (1)	HUP0100423A3 (no)
IL (1)	IL136592A (no)
NO (1)	NO20002904D0 (no)
NZ (1)	NZ504898A (no)
PL (1)	PL341601A1 (no)
PT (1)	PT1037888E (no)
TR (1)	TR200001633T2 (no)
TW (1)	TW505643B (no)
WO (1)	WO1999029685A1 (no)
ZA (1)	ZA9811154B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2235854T3 (es) *	1999-04-05	2005-07-16	Emisphere Technologies, Inc.	Sales disodicas, monohidratos y solvatos etanolicos para aportar agentes activos.
US20050026859A1 (en) *	2002-11-12	2005-02-03	John Hilfinger	Methods and compositions of gene delivery agents for systemic and local therapy
WO2007031933A2 (en)	2005-09-12	2007-03-22	Actelion Pharmaceuticals Ltd	Stable pharmaceutical composition comprising a pyrimidine-sulfamide
WO2007067779A2 (en) *	2005-12-08	2007-06-14	Tsrl, Inc.	Methods and compositions for drug delivery enhancement
WO2009061805A1 (en) *	2007-11-05	2009-05-14	Scolr Pharma, Inc.	Formulations for enhanced bioavailability of orally administered polar agents
US8805519B2 (en)	2010-09-30	2014-08-12	Nevro Corporation	Systems and methods for detecting intrathecal penetration
US10980999B2 (en)	2017-03-09	2021-04-20	Nevro Corp.	Paddle leads and delivery tools, and associated systems and methods
WO2019191423A1 (en)	2018-03-29	2019-10-03	Nevro Corp.	Leads having sidewall openings, and associated systems and methods

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4433764A1 (de) *	1994-09-22	1996-03-28	Asta Medica Ag	Darreichungsformen enthaltend alpha-Liponsäure, feste Salze von R-Thioctsäure mit verbesserter Freisetzung und Bioverfügbarkeit
MX9800975A (es) *	1995-08-02	1998-04-30	Smithkline Beecham Corp	Antagonistas de receptor de endotelina.

1998
- 1998-12-04 AR ARP980106187A patent/AR017426A1/es not_active Application Discontinuation
- 1998-12-04 CO CO98072345A patent/CO5021171A1/es unknown
- 1998-12-07 BR BR9813409-4A patent/BR9813409A/pt not_active Application Discontinuation
- 1998-12-07 PL PL98341601A patent/PL341601A1/xx unknown
- 1998-12-07 AT AT98961951T patent/ATE223404T1/de not_active IP Right Cessation
- 1998-12-07 PT PT98961951T patent/PT1037888E/pt unknown
- 1998-12-07 DE DE69807745T patent/DE69807745T2/de not_active Expired - Fee Related
- 1998-12-07 JP JP2000524279A patent/JP2001525405A/ja not_active Withdrawn
- 1998-12-07 NZ NZ504898A patent/NZ504898A/xx unknown
- 1998-12-07 IL IL13659298A patent/IL136592A/xx not_active IP Right Cessation
- 1998-12-07 KR KR1020007006162A patent/KR20010040292A/ko not_active Withdrawn
- 1998-12-07 ES ES98961951T patent/ES2182383T3/es not_active Expired - Lifetime
- 1998-12-07 CA CA002312965A patent/CA2312965A1/en not_active Abandoned
- 1998-12-07 AU AU17138/99A patent/AU747108B2/en not_active Ceased
- 1998-12-07 CN CN98811945A patent/CN1281447A/zh active Pending
- 1998-12-07 EP EP98961951A patent/EP1037888B1/en not_active Expired - Lifetime
- 1998-12-07 DK DK98961951T patent/DK1037888T3/da active
- 1998-12-07 US US09/581,066 patent/US6300359B1/en not_active Expired - Fee Related
- 1998-12-07 HU HU0100423A patent/HUP0100423A3/hu unknown
- 1998-12-07 TR TR2000/01633T patent/TR200001633T2/xx unknown
- 1998-12-07 ZA ZA9811154A patent/ZA9811154B/xx unknown
- 1998-12-07 WO PCT/US1998/025903 patent/WO1999029685A1/en not_active Ceased
1999
- 1999-01-20 TW TW087120292A patent/TW505643B/zh active
2000
- 2000-06-07 NO NO20002904A patent/NO20002904D0/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
NO20002904L (no)	2000-06-07
TR200001633T2 (tr)	2001-07-23
HK1032229A1 (en)	2001-07-13
EP1037888B1 (en)	2002-09-04
PT1037888E (pt)	2002-12-31
CN1281447A (zh)	2001-01-24
AR017426A1 (es)	2001-09-05
TW505643B (en)	2002-10-11
ATE223404T1 (de)	2002-09-15
DE69807745T2 (de)	2003-05-15
ES2182383T3 (es)	2003-03-01
CO5021171A1 (es)	2001-03-27
AU1713899A (en)	1999-06-28
PL341601A1 (en)	2001-04-23
ZA9811154B (en)	1999-06-08
HUP0100423A2 (hu)	2002-05-29
HUP0100423A3 (en)	2002-08-28
IL136592A0 (en)	2001-06-14
JP2001525405A (ja)	2001-12-11
IL136592A (en)	2003-03-12
US6300359B1 (en)	2001-10-09
DK1037888T3 (da)	2003-01-06
BR9813409A (pt)	2000-10-10
NZ504898A (en)	2002-11-26
KR20010040292A (ko)	2001-05-15
WO1999029685A1 (en)	1999-06-17
EP1037888A4 (en)	2001-08-22
CA2312965A1 (en)	1999-06-17
AU747108B2 (en)	2002-05-09
EP1037888A1 (en)	2000-09-27
DE69807745D1 (de)	2002-10-10

Legal Events

Date	Code	Title	Description
2005-10-17	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
MA25635A1 (fr)	2002-12-31	Essai immunologique pour les insecticides neonicotinyles
ATE357097T1 (de)	2007-04-15	Automatisches wiederholungsaufforderungsprotokoll
MX9906600A (es)	1999-10-31	4-(3-heterociclil-1-benzoil)pirazoles
NO20001260D0 (no)	2000-03-10	Optisk kommunikasjonssystem
NO20032452D0 (no)	2003-05-28	Aryletersubstituerte imidazolkinoliner
DE50014679D1 (de)	2007-11-08	Substituierte indol-mannichbasen
IS5715A (is)	2001-05-31	Aðferð til smíði á 4-karboxýamínó-2-setnu-1,2,3,4-tetrahýdrókínólíni
MA26135A1 (fr)	2004-04-01	Dispositif pour la lutte contre les insectes.
PT1173435E (pt)	2003-12-31	Polimorfo de 5-¬4-¬2-(n-metil-n-(2-piridil)-amino)-etoxi\|benzil\|tiazolidino-2,4-diona sal de acido maleico
ATE308519T1 (de)	2005-11-15	2,3-substituierte indolverbindungen als cox-2 inhibitoren
BR9609849B1 (pt)	2010-05-18	derivados de 2-(4-substituìda) -benzilamino-2-metila-propanamida.
NO20002904L (no)	2000-06-07	(E)-3-[1-N-butyl-5-[2-(2-karboksylfenyl)metoksy-4-klorfenyl]- 1H-pyrazol-4-yl]-2-[(5-metoksy-2,3-dihydrobenzofuran-6-yl)methyl]- prop-2-ensyre monoagrininsalt
DE60017076D1 (de)	2005-02-03	Lasersystem
ID29138A (id)	2001-08-02	Metode untuk pelacakan data
FI19992720L (fi)	2001-06-18	Datapuhelun reititys IP-yhteyksillä
ATE525362T1 (de)	2011-10-15	2-(3-(4-(2-t-butyl-6-trifluormethylpyrimidin-4-
NO20003611D0 (no)	2000-07-13	Optisk kommunikasjonssystem
FI990417L (fi)	2000-08-27	Menetelmä luottamusrajan määrittämiseksi
IS5166A (is)	1999-08-27	Kristallað vatnað natríumsalt af (E)-4,6-díklóró-3-(2-oxó-1-fenýlpýrrólidín-3-ýliden metýl)-1h-indól-2-karboxýlsýru
DE59807563D1 (de)	2003-04-24	Substituierte 2-(3-alkenyl-benzoyl)-cyclohexan-1,3-dione
FR2782174B1 (fr)	2001-12-14	Assistance au pilotage stereoscopique
SI1037888T1 (en)	2003-02-28	(e)-3-(1-n-butyl- 5-(2-(2-carboxyphenyl)methoxy- 4-chlorophenyl)-1h- pyrazol-4-yl)-2- ((5- methoxy-2,3- dihydrobenzofuran-6-yl)methyl)- prop-2-enoic acid monoargininyl salt
ATE272624T1 (de)	2004-08-15	Substituierte 4-(3-alkenyl-benzoyl)-pyrazole
TR199801735A3 (tr)	1999-03-22	2-(arilfenil)amino-imidazolin türevleri.
IT1313578B1 (it)	2002-09-09	Metodo per l'essicamento di acido borico.