NO20002904D0 - (E)-3-[1-N-butyl-5-[2-(2-karboksylfenyl)metoksy-4-klorfenyl]- 1H-pyrazol-4-yl]-2-[(5-metoksy-2,3-dihydrobenzofuran-6-yl)methyl]- prop-2-ensyre monoagrininsalt - Google Patents

(E)-3-[1-N-butyl-5-[2-(2-karboksylfenyl)metoksy-4-klorfenyl]- 1H-pyrazol-4-yl]-2-[(5-metoksy-2,3-dihydrobenzofuran-6-yl)methyl]- prop-2-ensyre monoagrininsalt

Info

Publication number
NO20002904D0
NO20002904D0 NO20002904A NO20002904A NO20002904D0 NO 20002904 D0 NO20002904 D0 NO 20002904D0 NO 20002904 A NO20002904 A NO 20002904A NO 20002904 A NO20002904 A NO 20002904A NO 20002904 D0 NO20002904 D0 NO 20002904D0
Authority
NO
Norway
Prior art keywords
methoxy
monoagrinin
carboxylphenyl
dihydrobenzofuran
pyrazol
Prior art date
Application number
NO20002904A
Other languages
English (en)
Other versions
NO20002904L (no
Inventor
Joseph Robert Flisak
Albert Stephen Kearney
Nagesh Palepu
Cherng-Yih Perng
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of NO20002904D0 publication Critical patent/NO20002904D0/no
Publication of NO20002904L publication Critical patent/NO20002904L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/06—Anti-spasmodics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20002904A 1997-12-08 2000-06-07 (E)-3-[1-N-butyl-5-[2-(2-karboksylfenyl)metoksy-4-klorfenyl]- 1H-pyrazol-4-yl]-2-[(5-metoksy-2,3-dihydrobenzofuran-6-yl)methyl]- prop-2-ensyre monoagrininsalt NO20002904L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6773297P 1997-12-08 1997-12-08
PCT/US1998/025903 WO1999029685A1 (en) 1997-12-08 1998-12-07 (e)-3-[1-n-butyl- 5-[2-(2-carboxyphenyl)methoxy- 4-chlorophenyl]-1h- pyrazol-4-yl]-2-[(5- methoxy-2,3- dihydrobenzofuran-6-yl)methyl]- prop-2-enoic acid monoargininyl salt

Publications (2)

Publication Number Publication Date
NO20002904D0 true NO20002904D0 (no) 2000-06-07
NO20002904L NO20002904L (no) 2000-06-07

Family

ID=22078027

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20002904A NO20002904L (no) 1997-12-08 2000-06-07 (E)-3-[1-N-butyl-5-[2-(2-karboksylfenyl)metoksy-4-klorfenyl]- 1H-pyrazol-4-yl]-2-[(5-metoksy-2,3-dihydrobenzofuran-6-yl)methyl]- prop-2-ensyre monoagrininsalt

Country Status (24)

Country Link
US (1) US6300359B1 (no)
EP (1) EP1037888B1 (no)
JP (1) JP2001525405A (no)
KR (1) KR20010040292A (no)
CN (1) CN1281447A (no)
AR (1) AR017426A1 (no)
AT (1) ATE223404T1 (no)
AU (1) AU747108B2 (no)
BR (1) BR9813409A (no)
CA (1) CA2312965A1 (no)
CO (1) CO5021171A1 (no)
DE (1) DE69807745T2 (no)
DK (1) DK1037888T3 (no)
ES (1) ES2182383T3 (no)
HU (1) HUP0100423A3 (no)
IL (1) IL136592A (no)
NO (1) NO20002904L (no)
NZ (1) NZ504898A (no)
PL (1) PL341601A1 (no)
PT (1) PT1037888E (no)
TR (1) TR200001633T2 (no)
TW (1) TW505643B (no)
WO (1) WO1999029685A1 (no)
ZA (1) ZA9811154B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ534409A (en) 1999-04-05 2006-03-31 Emisphere Tech Inc Disodium salts, monohydrates, and ethanol solvates for delivering active agents
US20050026859A1 (en) * 2002-11-12 2005-02-03 John Hilfinger Methods and compositions of gene delivery agents for systemic and local therapy
WO2007031933A2 (en) 2005-09-12 2007-03-22 Actelion Pharmaceuticals Ltd Stable pharmaceutical composition comprising a pyrimidine-sulfamide
WO2007067779A2 (en) * 2005-12-08 2007-06-14 Tsrl, Inc. Methods and compositions for drug delivery enhancement
CN103536923A (zh) * 2007-11-05 2014-01-29 阿拉维制药公司 用于口服给药极性药剂的提高生物利用度的制剂
US8805519B2 (en) 2010-09-30 2014-08-12 Nevro Corporation Systems and methods for detecting intrathecal penetration
EP3579914A4 (en) 2017-03-09 2020-11-25 Nevro Corp. PALLET BYPASSES AND SETTING TOOLS, AND ASSOCIATED SYSTEMS AND PROCESSES
EP3758793A4 (en) 2018-03-29 2021-12-08 Nevro Corp. WIRES WITH SIDE WALL OPENINGS AND ASSOCIATED SYSTEMS AND PROCESSES

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4433764A1 (de) * 1994-09-22 1996-03-28 Asta Medica Ag Darreichungsformen enthaltend alpha-Liponsäure, feste Salze von R-Thioctsäure mit verbesserter Freisetzung und Bioverfügbarkeit
WO1997004772A1 (en) * 1995-08-02 1997-02-13 Smithkline Beecham Corporation Endothelin receptor antagonists

Also Published As

Publication number Publication date
DE69807745D1 (de) 2002-10-10
AU747108B2 (en) 2002-05-09
PL341601A1 (en) 2001-04-23
CN1281447A (zh) 2001-01-24
HUP0100423A2 (hu) 2002-05-29
DK1037888T3 (da) 2003-01-06
CA2312965A1 (en) 1999-06-17
US6300359B1 (en) 2001-10-09
HUP0100423A3 (en) 2002-08-28
JP2001525405A (ja) 2001-12-11
AU1713899A (en) 1999-06-28
WO1999029685A1 (en) 1999-06-17
EP1037888A4 (en) 2001-08-22
DE69807745T2 (de) 2003-05-15
ES2182383T3 (es) 2003-03-01
NO20002904L (no) 2000-06-07
KR20010040292A (ko) 2001-05-15
IL136592A (en) 2003-03-12
EP1037888B1 (en) 2002-09-04
BR9813409A (pt) 2000-10-10
TR200001633T2 (tr) 2001-07-23
AR017426A1 (es) 2001-09-05
HK1032229A1 (en) 2001-07-13
PT1037888E (pt) 2002-12-31
CO5021171A1 (es) 2001-03-27
ATE223404T1 (de) 2002-09-15
IL136592A0 (en) 2001-06-14
ZA9811154B (en) 1999-06-08
TW505643B (en) 2002-10-11
EP1037888A1 (en) 2000-09-27
NZ504898A (en) 2002-11-26

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