NO20003104L - KaliumkanalÕpnere - Google Patents

KaliumkanalÕpnere

Info

Publication number
NO20003104L
NO20003104L NO20003104A NO20003104A NO20003104L NO 20003104 L NO20003104 L NO 20003104L NO 20003104 A NO20003104 A NO 20003104A NO 20003104 A NO20003104 A NO 20003104A NO 20003104 L NO20003104 L NO 20003104L
Authority
NO
Norway
Prior art keywords
opening
potassium channel
kaliumkanalõpnere
potassium
ameliorated
Prior art date
Application number
NO20003104A
Other languages
English (en)
Other versions
NO317099B1 (no
NO20003104D0 (no
Inventor
William A Carroll
Mark W Holladay
James P Sullivan
Irene Drizin
Henry Q Zhang
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/206,055 external-priority patent/US6265417B1/en
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of NO20003104D0 publication Critical patent/NO20003104D0/no
Publication of NO20003104L publication Critical patent/NO20003104L/no
Publication of NO317099B1 publication Critical patent/NO317099B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
    • C07C45/298—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with manganese derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nutrition Science (AREA)
  • Urology & Nephrology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Glass Compositions (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Feeding And Controlling Fuel (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Toys (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogen, Water And Hydrids (AREA)
  • Pyridine Compounds (AREA)
  • Ladders (AREA)
  • Gyroscopes (AREA)
  • Weting (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
NO20003104A 1997-12-18 2000-06-16 Kaliumkanalapnere NO317099B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US99339297A 1997-12-18 1997-12-18
US09/206,055 US6265417B1 (en) 1997-12-18 1998-12-04 Potassium channel openers
PCT/US1998/026780 WO1999031059A1 (en) 1997-12-18 1998-12-16 Potassium channel openers

Publications (3)

Publication Number Publication Date
NO20003104D0 NO20003104D0 (no) 2000-06-16
NO20003104L true NO20003104L (no) 2000-08-17
NO317099B1 NO317099B1 (no) 2004-08-09

Family

ID=26901004

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20003104A NO317099B1 (no) 1997-12-18 2000-06-16 Kaliumkanalapnere

Country Status (21)

Country Link
US (1) US20010036950A1 (no)
EP (1) EP1040097B1 (no)
JP (1) JP2002508354A (no)
CN (1) CN1158259C (no)
AT (1) ATE264303T1 (no)
AU (1) AU756505B2 (no)
BG (1) BG64309B1 (no)
BR (1) BR9813634A (no)
CA (1) CA2314948A1 (no)
DE (1) DE69823227T2 (no)
DK (1) DK1040097T3 (no)
ES (1) ES2222000T3 (no)
HU (1) HUP0100112A3 (no)
IL (1) IL135985A0 (no)
NO (1) NO317099B1 (no)
NZ (1) NZ504371A (no)
PL (1) PL341298A1 (no)
PT (1) PT1040097E (no)
SK (1) SK8732000A3 (no)
TR (1) TR200001715T2 (no)
WO (1) WO1999031059A1 (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6265417B1 (en) 1997-12-18 2001-07-24 Abbott Laboratories Potassium channel openers
US6593335B1 (en) 1997-12-18 2003-07-15 Abbott Laboratories Potassium channel openers
US6191140B1 (en) * 1998-10-28 2001-02-20 Abbott Laboratories Pyrano, piperidino, and thiopyrano compounds and methods of use
US6642222B2 (en) 1998-10-28 2003-11-04 Abbott Laboratories Pyrano, piperidino, and thiopyrano compounds and methods of use
JP2002528452A (ja) * 1998-10-28 2002-09-03 アボット・ラボラトリーズ ジヒドロピリジン化合物および使用方法
US6518279B2 (en) * 1999-03-04 2003-02-11 Abbott Laboratories Cyclopentanone dihydropyridine compounds useful as potassium channel openers
MXPA03000436A (es) * 2000-07-18 2003-06-24 Yamanouchi Pharma Co Ltd Medicamentos que compreden derivados de dicianopiridina.
MXPA04008072A (es) * 2002-02-19 2004-11-26 Abbott Lab Yodinacion de 4-fluoro-benzaldehido.

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2658804A1 (de) * 1976-12-24 1978-07-06 Bayer Ag Kreislaufbeeinflussende mittel
DE2747513A1 (de) * 1977-10-22 1979-05-03 Bayer Ag Dihydropyridine mit schwefelhaltigen estergruppierungen
US4777167A (en) * 1986-04-09 1988-10-11 Ortho Pharmaceutical Corporation Pharmaceutically useful substituted thiacycloalkeno [3,2-b]pyridines, compositions and method of use
US4879384A (en) * 1988-06-15 1989-11-07 Ortho Pharmaceutical Corporation Preparation of thiocycloalkno [3,2-b] pyridines
US5075440A (en) * 1990-05-03 1991-12-24 Ortho Pharmaceutical Corporation Novel pyrido[2,3-f](1,4)thiazepines and pyrido[3,2-b](1,5)benzothiazepines
JP3285963B2 (ja) * 1991-10-21 2002-05-27 インペリアル・ケミカル・インダストリーズ・ピーエルシー 治療剤
GB9318935D0 (en) * 1992-10-20 1993-10-27 Zeneca Ltd Heterocyclic derivatives
DE4424678A1 (de) * 1994-07-13 1996-01-18 Bayer Ag Dioxo-thiopyrano-pyridin-carbonsäure-derivate

Also Published As

Publication number Publication date
AU1830799A (en) 1999-07-05
HK1032583A1 (en) 2001-07-27
DK1040097T3 (da) 2004-08-02
ES2222000T3 (es) 2005-01-16
BG104594A (en) 2001-03-30
PL341298A1 (en) 2001-04-09
CA2314948A1 (en) 1999-06-24
SK8732000A3 (en) 2000-11-07
WO1999031059A1 (en) 1999-06-24
BG64309B1 (bg) 2004-09-30
PT1040097E (pt) 2004-08-31
DE69823227T2 (de) 2005-03-10
HUP0100112A3 (en) 2004-05-28
NO317099B1 (no) 2004-08-09
US20010036950A1 (en) 2001-11-01
DE69823227D1 (de) 2004-05-19
BR9813634A (pt) 2000-10-17
CN1158259C (zh) 2004-07-21
AU756505B2 (en) 2003-01-16
ATE264303T1 (de) 2004-04-15
TR200001715T2 (tr) 2000-12-21
JP2002508354A (ja) 2002-03-19
EP1040097A1 (en) 2000-10-04
HUP0100112A2 (hu) 2001-08-28
NO20003104D0 (no) 2000-06-16
EP1040097B1 (en) 2004-04-14
IL135985A0 (en) 2001-05-20
NZ504371A (en) 2002-02-01
CN1282321A (zh) 2001-01-31

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