NO20003285D0 - Tetrahydrobenzenindolderivater - Google Patents

Tetrahydrobenzenindolderivater

Info

Publication number
NO20003285D0
NO20003285D0 NO20003285A NO20003285A NO20003285D0 NO 20003285 D0 NO20003285 D0 NO 20003285D0 NO 20003285 A NO20003285 A NO 20003285A NO 20003285 A NO20003285 A NO 20003285A NO 20003285 D0 NO20003285 D0 NO 20003285D0
Authority
NO
Norway
Prior art keywords
hydrogen atom
integer
group
specified substituent
lower alkyl
Prior art date
Application number
NO20003285A
Other languages
English (en)
Other versions
NO20003285L (no
NO317293B1 (no
Inventor
Chika Kikuchi
Takashi Ando
Kazuyuki Fuji
Masayo Okuno
Eriko Morita
Masako Imai
Osamu Ushiroda
Masao Koyama
Toyokazu Hiranuma
Original Assignee
Meiji Seika Kaisha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP35838197A external-priority patent/JPH11189585A/ja
Application filed by Meiji Seika Kaisha filed Critical Meiji Seika Kaisha
Publication of NO20003285D0 publication Critical patent/NO20003285D0/no
Publication of NO20003285L publication Critical patent/NO20003285L/no
Publication of NO317293B1 publication Critical patent/NO317293B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/90—Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles
    • C07D209/92—Naphthostyrils
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO20003285A 1997-12-25 2000-06-22 Tetrahydrobenzindolderivat, farmasoytisk preparat samt mellomproduktforbindelse NO317293B1 (no)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
JP35838097 1997-12-25
JP35838197A JPH11189585A (ja) 1997-12-25 1997-12-25 5−ht7受容体結合能を有するテトラヒドロベンズインドール誘導体
JP8591398 1998-03-31
JP13687298 1998-05-19
JP22970998 1998-08-14
JP31933698 1998-11-10
PCT/JP1998/005827 WO1999033804A1 (en) 1997-12-25 1998-12-22 Tetrahydrobenzindole derivatives

Publications (3)

Publication Number Publication Date
NO20003285D0 true NO20003285D0 (no) 2000-06-22
NO20003285L NO20003285L (no) 2000-08-23
NO317293B1 NO317293B1 (no) 2004-10-04

Family

ID=27551662

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20003285A NO317293B1 (no) 1997-12-25 2000-06-22 Tetrahydrobenzindolderivat, farmasoytisk preparat samt mellomproduktforbindelse

Country Status (12)

Country Link
US (1) US6498251B1 (no)
EP (1) EP1057814B1 (no)
JP (1) JP4459437B2 (no)
KR (1) KR100588249B1 (no)
CN (1) CN1129578C (no)
AT (1) ATE290527T1 (no)
CA (1) CA2316388C (no)
DE (1) DE69829317T2 (no)
DK (1) DK1057814T3 (no)
ES (1) ES2238778T3 (no)
NO (1) NO317293B1 (no)
WO (1) WO1999033804A1 (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6407112B1 (en) * 1998-04-22 2002-06-18 Meiji Seika Kaisha, Ltd. Optically active tetrahydrobenzindole derivative
UA69420C2 (uk) 1998-10-06 2004-09-15 Янссен Фармацевтика Н.В. ТРИЦИКЛІЧНІ <font face="Symbol">D3</font>-ПІПЕРИДИНИ ЯК <font face="Symbol">a<sub></font>2</sub>-АНТАГОНІСТИ
GB9828004D0 (en) * 1998-12-18 1999-02-10 Smithkline Beecham Plc Use
WO2001029029A1 (en) * 1999-10-18 2001-04-26 Smithkline Beecham P.L.C. Tetrahydrobenzindolone derivatives, their preparation and their use as 5-ht7 receptor antagonists
AR035417A1 (es) * 2001-01-27 2004-05-26 Hoffmann La Roche Derivados triciclicos de lactama y sultama, procesos para su elaboracion, medicamentos que los contienen, y el uso de dichos compuestos en la preparacion de medicamentos
AU2003256793A1 (en) * 2002-08-20 2004-03-11 Eli Lilly And Company Substituted azepines as histamine h3 receptor antagonists, preparation and therapeutic uses
WO2005012310A1 (ja) * 2003-08-04 2005-02-10 Soda Aromatic Co.,Ltd. チエノピリジン系化合物の香料における使用、および新規チエノピリジン系化合物
SK51052006A3 (sk) * 2004-05-11 2007-05-03 Egis Gy�gyszergy�r Nyrt. Pyridínové deriváty alkyloxindolov ako aktívne látky voči 5-HT7 receptoru
ATE461925T1 (de) * 2005-04-26 2010-04-15 Hypnion Inc Benzisoxazolpiperidinverbindungen und verfahren zu deren anwendung
TW200823215A (en) * 2006-08-04 2008-06-01 Merz Pharma Gmbh & Amp Co Kgaa Pyrazolopyrimidines, a process for their preparation and the use as a medicine
EP1956006A1 (en) * 2007-02-06 2008-08-13 Laboratorios del Dr. Esteve S.A. Heterocyclyl-substituted-tetrahydro-naphthalen derivatives as 5-HT7 receptor ligands
EP1975161A1 (en) 2007-03-28 2008-10-01 Laboratorios del Dr. Esteve S.A. Heterocyclyl-substituted- tetrahydro-napthalen-amine derivatives, their preparation and use as medicaments
TWI443098B (zh) * 2008-03-24 2014-07-01 Medivation Technologies Inc 吡啶并〔3,4-b〕吲哚及使用方法
EP2480079A4 (en) * 2009-09-23 2015-04-08 Medivation Technologies Inc PYRIDO- (3,4-B-) INDOLE AND USE METHOD THEREFOR
CN108623585B (zh) * 2018-05-22 2021-07-09 中国人民解放军第二军医大学 β-四氢咔啉类抗真菌药物及其制备方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998000400A1 (en) * 1996-06-28 1998-01-08 Meiji Seika Kaisha, Ltd. Tetrahydrobenzindole compounds
US6407112B1 (en) 1998-04-22 2002-06-18 Meiji Seika Kaisha, Ltd. Optically active tetrahydrobenzindole derivative

Also Published As

Publication number Publication date
DE69829317T2 (de) 2006-04-06
DE69829317D1 (de) 2005-04-14
WO1999033804A1 (en) 1999-07-08
JP4459437B2 (ja) 2010-04-28
CN1129578C (zh) 2003-12-03
CA2316388C (en) 2009-09-08
DK1057814T3 (da) 2005-07-04
KR100588249B1 (ko) 2006-06-13
EP1057814A1 (en) 2000-12-06
EP1057814B1 (en) 2005-03-09
NO20003285L (no) 2000-08-23
EP1057814A4 (en) 2001-07-11
CN1286683A (zh) 2001-03-07
KR20010033609A (ko) 2001-04-25
NO317293B1 (no) 2004-10-04
CA2316388A1 (en) 1999-07-08
US6498251B1 (en) 2002-12-24
ES2238778T3 (es) 2005-09-01
ATE290527T1 (de) 2005-03-15

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Legal Events

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Free format text: TETRAHYDROBENZINDOLDERIVAT, FARMASOYTISK PREPARAT SAMT MELLOMPRODUKTFORBINDELSE

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