NO20004316L - Meta azacyclic aminobenzoic acid compounds and derivatives thereof which are integrin antagonists - Google Patents

Meta azacyclic aminobenzoic acid compounds and derivatives thereof which are integrin antagonists

Info

Publication number
NO20004316L
NO20004316L NO20004316A NO20004316A NO20004316L NO 20004316 L NO20004316 L NO 20004316L NO 20004316 A NO20004316 A NO 20004316A NO 20004316 A NO20004316 A NO 20004316A NO 20004316 L NO20004316 L NO 20004316L
Authority
NO
Norway
Prior art keywords
meta
derivatives
acid compounds
aminobenzoic acid
integrin antagonists
Prior art date
Application number
NO20004316A
Other languages
Norwegian (no)
Other versions
NO20004316D0 (en
NO315703B1 (en
Inventor
Thomas E Rogers
Peter G Ruminski
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of NO20004316D0 publication Critical patent/NO20004316D0/en
Publication of NO20004316L publication Critical patent/NO20004316L/en
Publication of NO315703B1 publication Critical patent/NO315703B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D239/08—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms directly attached in position 2
    • C07D239/12—Nitrogen atoms not forming part of a nitro radical
    • C07D239/14—Nitrogen atoms not forming part of a nitro radical with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to said nitrogen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO20004316A 1998-03-04 2000-08-30 Meta azacyclic aminobenzoic acid compounds and derivatives thereof which are integrin antagonists NO315703B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3427098A 1998-03-04 1998-03-04
PCT/US1999/003281 WO1999044994A1 (en) 1998-03-04 1999-02-22 Meta-azacyclic amino benzoic acid compounds and derivatives thereof being integrin antagonists

Publications (3)

Publication Number Publication Date
NO20004316D0 NO20004316D0 (en) 2000-08-30
NO20004316L true NO20004316L (en) 2000-11-06
NO315703B1 NO315703B1 (en) 2003-10-13

Family

ID=21875345

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20004316A NO315703B1 (en) 1998-03-04 2000-08-30 Meta azacyclic aminobenzoic acid compounds and derivatives thereof which are integrin antagonists

Country Status (29)

Country Link
EP (1) EP1060164A1 (en)
JP (1) JP2002505323A (en)
KR (1) KR20010041584A (en)
CN (1) CN1214011C (en)
AP (1) AP1244A (en)
AR (1) AR018139A1 (en)
AU (1) AU753230B2 (en)
BG (1) BG104740A (en)
BR (1) BR9908470A (en)
CA (1) CA2322207A1 (en)
EA (1) EA200000804A1 (en)
EE (1) EE200000506A (en)
GE (1) GEP20033118B (en)
HR (1) HRP20000574A2 (en)
HU (1) HUP0100865A3 (en)
ID (1) ID25591A (en)
IL (1) IL137653A0 (en)
IS (1) IS5582A (en)
MY (1) MY123908A (en)
NO (1) NO315703B1 (en)
NZ (1) NZ506598A (en)
OA (1) OA11530A (en)
PL (1) PL342726A1 (en)
SK (1) SK13002000A3 (en)
TR (1) TR200002542T2 (en)
UA (1) UA71906C2 (en)
WO (1) WO1999044994A1 (en)
YU (1) YU52000A (en)
ZA (1) ZA994406B (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9805655D0 (en) 1998-03-16 1998-05-13 Celltech Therapeutics Ltd Chemical compounds
GB9814414D0 (en) 1998-07-03 1998-09-02 Celltech Therapeutics Ltd Chemical compounds
GB9821061D0 (en) 1998-09-28 1998-11-18 Celltech Therapeutics Ltd Chemical compounds
GB9826174D0 (en) 1998-11-30 1999-01-20 Celltech Therapeutics Ltd Chemical compounds
US6518283B1 (en) 1999-05-28 2003-02-11 Celltech R&D Limited Squaric acid derivatives
US6455539B2 (en) 1999-12-23 2002-09-24 Celltech R&D Limited Squaric acid derivates
DE60130910T2 (en) 2000-04-17 2008-07-10 Ucb Pharma, S.A. ENAMINE DERIVATIVES AS CELL ADHESION MOLECULES
US6403608B1 (en) 2000-05-30 2002-06-11 Celltech R&D, Ltd. 3-Substituted isoquinolin-1-yl derivatives
US6545013B2 (en) 2000-05-30 2003-04-08 Celltech R&D Limited 2,7-naphthyridine derivatives
US6921767B2 (en) * 2000-06-15 2005-07-26 Pharmacia Corporation Cycloalkyl alkanoic acids as integrin receptor antagonists derivatives
CA2417059A1 (en) 2000-08-02 2002-02-07 Celltech R&D Limited 3-substituted isoquinolin-1-yl derivatives
EP1572210A1 (en) * 2002-12-20 2005-09-14 Pharmacia Corporation The r-isomer of beta amino acid compounds as integrin receptor antagonists derivatives
UA87854C2 (en) 2004-06-07 2009-08-25 Мерк Энд Ко., Инк. N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators
AU2006257815A1 (en) * 2005-06-10 2006-12-21 Bipar Sciences, Inc. PARP modulators and treatment of cancer
EP2131861A2 (en) 2007-03-01 2009-12-16 Mallinckrodt Inc. Integrated photoactive small molecules and uses thereof
JP4792124B1 (en) * 2010-11-15 2011-10-12 エフイートレード株式会社 Method for molding protective film for vehicle and method for manufacturing protective film for vehicle
IN2015DN00099A (en) 2012-07-18 2015-05-29 Univ Saint Louis
US8716226B2 (en) 2012-07-18 2014-05-06 Saint Louis University 3,5 phenyl-substituted beta amino acid derivatives as integrin antagonists
ES2864079T3 (en) 2014-05-30 2021-10-13 Pfizer Carbonitrile derivatives as selective androgen receptor modulators
WO2015187774A1 (en) * 2014-06-04 2015-12-10 Monsanto Technology Llc 3,6-dichlorosalicylic acid compounds and related synthetic processes
HK1244806A1 (en) 2015-12-30 2018-08-17 Saint Louis University Meta-azacyclic amino benzoic acid derivatives as pan integrin antagonists
JP7661969B2 (en) 2020-05-14 2025-04-15 Ube株式会社 1,4,5,6-Tetrahydropyrimidin-2-amine derivatives
WO2023275715A1 (en) 2021-06-30 2023-01-05 Pfizer Inc. Metabolites of selective androgen receptor modulators
JPWO2023085396A1 (en) 2021-11-12 2023-05-19

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9801716A (en) * 1995-08-30 1998-05-31 Searle & Co Meta-guanidine, urea, thiourea or azacyclic amino benzoic acid derivatives as integrin antagonists.

Also Published As

Publication number Publication date
BR9908470A (en) 2000-12-05
ID25591A (en) 2000-10-19
TR200002542T2 (en) 2001-05-21
MY123908A (en) 2006-06-30
PL342726A1 (en) 2001-07-02
NZ506598A (en) 2003-07-25
JP2002505323A (en) 2002-02-19
NO20004316D0 (en) 2000-08-30
NO315703B1 (en) 2003-10-13
IS5582A (en) 2000-08-04
SK13002000A3 (en) 2001-07-10
EE200000506A (en) 2002-04-15
AU3294799A (en) 1999-09-20
EP1060164A1 (en) 2000-12-20
AP1244A (en) 2004-02-04
EA200000804A1 (en) 2001-04-23
HUP0100865A3 (en) 2001-11-28
KR20010041584A (en) 2001-05-25
ZA994406B (en) 2000-02-11
GEP20033118B (en) 2003-11-25
CA2322207A1 (en) 1999-09-10
AR018139A1 (en) 2001-10-31
WO1999044994A1 (en) 1999-09-10
YU52000A (en) 2003-02-28
IL137653A0 (en) 2001-10-31
CN1291978A (en) 2001-04-18
OA11530A (en) 2004-05-17
CN1214011C (en) 2005-08-10
HUP0100865A2 (en) 2001-08-28
BG104740A (en) 2001-02-28
AU753230B2 (en) 2002-10-10
HRP20000574A2 (en) 2001-08-31
UA71906C2 (en) 2005-01-17
AP2000001893A0 (en) 2000-09-30

Similar Documents

Publication Publication Date Title
NO20004316D0 (en) Meta azacyclic aminobenzoic acid compounds and derivatives thereof which are integrin antagonists
ATE289212T1 (en) VIAL FOR IMPLANT
ATE358670T1 (en) AROMATIC NITROGEN-CONTAINING SIX-RING COMPOUNDS
DE60023211D1 (en) material testing
DE19983276T1 (en) Solid state transformer
NO20020307L (en) N- (indolecarbonyl) -piperazine
ATE195121T1 (en) PAROXETINE METHANESULFONATE
ATE419231T1 (en) MONO-SUBSTITUTED 3-PROPYL-GAMMA-AMINOBUTTERIC ACID
ID29089A (en) MOKSIFLOXASIN PHARMACEUTICAL PROPERTIES
NO994626L (en) Substituted benzamides
DE60038322D1 (en) recorder
ID26665A (en) VLA-4 ANTAGONISTS
DE69932639D1 (en) DATA INTEGRITY MONITORING
DK1056448T3 (en) Pharmaceutical combinations with tramadol
ID27150A (en) PHARMACEUTICAL MATERIALS LEVOTIROXIDE
PL364757A1 (en) Compound screening test
ATE252547T1 (en) MATRIXMETALLOPROTEINASE INHIBITORS
NO20010165D0 (en) polyisocyanate
ID27605A (en) TERNAL RECORDER MATERIALS
DE60032034D1 (en) recorder
NO20015237L (en) Integrin antagonists
NO990717D0 (en) Monitor st ° ttemekanisme
DE50003014D1 (en) N-SUBSTITUTED PERHYDRODIAZINE
DE69824255D1 (en) deformylase
DE60030196D1 (en) recorder

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees