NO20004601L - A system for confocal microscopy imaging - Google Patents

A system for confocal microscopy imaging

Info

Publication number
NO20004601L
NO20004601L NO20004601A NO20004601A NO20004601L NO 20004601 L NO20004601 L NO 20004601L NO 20004601 A NO20004601 A NO 20004601A NO 20004601 A NO20004601 A NO 20004601A NO 20004601 L NO20004601 L NO 20004601L
Authority
NO
Norway
Prior art keywords
confocal microscopy
microscopy imaging
ccd
designed
imaging system
Prior art date
Application number
NO20004601A
Other languages
Norwegian (no)
Other versions
NO20004601D0 (en
Inventor
Jay K Trautman
Timothy D Harris
Richard L Hansen
William Karsh
Neal A Nicklaus
Original Assignee
Praelux Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Praelux Inc filed Critical Praelux Inc
Publication of NO20004601D0 publication Critical patent/NO20004601D0/en
Publication of NO20004601L publication Critical patent/NO20004601L/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5002—Partitioning blood components
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0028—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders specially adapted for specific applications, e.g. for endoscopes, ophthalmoscopes, attachments to conventional microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/006—Optical details of the image generation focusing arrangements; selection of the plane to be imaged
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0064—Optical details of the image generation multi-spectral or wavelength-selective arrangements, e.g. wavelength fan-out, chromatic profiling
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0072—Optical details of the image generation details concerning resolution or correction, including general design of CSOM objectives
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052—Optical details of the image generation
    • G02B21/0076—Optical details of the image generation arrangements using fluorescence or luminescence
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/0004—Microscopes specially adapted for specific applications
    • G02B21/002—Scanning microscopes
    • G02B21/0024—Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/008—Details of detection or image processing, including general computer control
    • G02B21/0084—Details of detection or image processing, including general computer control time-scale detection, e.g. strobed, ultra-fast, heterodyne detection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy

Landscapes

  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Biomedical Technology (AREA)
  • Radiology & Medical Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Ophthalmology & Optometry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Microscoopes, Condenser (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Et konfokalt avbildningssystem som bruker en linjeformet strålebunt. Spesifikke realiseringer er innrettet for apparatur med lysfølsomme kretser (CCD, charge coupled devices) og slike hvor apparaturen brukes til observasjon av fluorescerende gjenstander.A confocal imaging system that uses a linear beam. Specific realizations are designed for apparatus with light-sensitive circuits (CCD, charge coupled devices) and such where the apparatus is used for observing fluorescent objects.

NO20004601A 1998-03-16 2000-09-15 A system for confocal microscopy imaging NO20004601L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4252798A 1998-03-16 1998-03-16
PCT/US1999/005589 WO1999047963A1 (en) 1998-03-16 1999-03-16 Confocal microscopy imaging system

Publications (2)

Publication Number Publication Date
NO20004601D0 NO20004601D0 (en) 2000-09-15
NO20004601L true NO20004601L (en) 2000-11-10

Family

ID=21922413

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20004601A NO20004601L (en) 1998-03-16 2000-09-15 A system for confocal microscopy imaging

Country Status (10)

Country Link
EP (1) EP1064579A4 (en)
JP (1) JP4812937B2 (en)
KR (2) KR100560588B1 (en)
CN (1) CN100380160C (en)
AU (1) AU758571B2 (en)
BR (1) BR9908767B1 (en)
CA (1) CA2324262C (en)
IL (2) IL138496A0 (en)
NO (1) NO20004601L (en)
WO (1) WO1999047963A1 (en)

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Also Published As

Publication number Publication date
IL164319A0 (en) 2005-12-18
JP2002507762A (en) 2002-03-12
WO1999047963A1 (en) 1999-09-23
NO20004601D0 (en) 2000-09-15
IL138496A0 (en) 2001-10-31
EP1064579A4 (en) 2007-11-07
KR20010041945A (en) 2001-05-25
KR20050088500A (en) 2005-09-06
BR9908767B1 (en) 2011-09-06
WO1999047963A9 (en) 1999-12-23
WO1999047963A8 (en) 1999-11-18
CA2324262C (en) 2010-05-25
AU3354799A (en) 1999-10-11
AU758571B2 (en) 2003-03-27
KR100618502B1 (en) 2006-09-01
KR100560588B1 (en) 2006-03-16
BR9908767A (en) 2001-10-16
EP1064579A1 (en) 2001-01-03
CN100380160C (en) 2008-04-09
CA2324262A1 (en) 1999-09-23
CN1301357A (en) 2001-06-27
JP4812937B2 (en) 2011-11-09

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