NO20004980L - Partikulære varer av aktive ingredienser for den pulmonale anvendelsen - Google Patents

Partikulære varer av aktive ingredienser for den pulmonale anvendelsen

Info

Publication number
NO20004980L
NO20004980L NO20004980A NO20004980A NO20004980L NO 20004980 L NO20004980 L NO 20004980L NO 20004980 A NO20004980 A NO 20004980A NO 20004980 A NO20004980 A NO 20004980A NO 20004980 L NO20004980 L NO 20004980L
Authority
NO
Norway
Prior art keywords
active ingredients
particulate
pulmonary use
particulate articles
pulmonary
Prior art date
Application number
NO20004980A
Other languages
English (en)
Other versions
NO20004980D0 (no
Inventor
Holger Bengs
Juergen Grande
Original Assignee
Axiva Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Axiva Gmbh filed Critical Axiva Gmbh
Publication of NO20004980D0 publication Critical patent/NO20004980D0/no
Publication of NO20004980L publication Critical patent/NO20004980L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Oppfinnelsen angår tilveiebringelse av en partikulær virkestoffbærer og dens farmasøytiske sammensetning med depotvirkning for pulmonal applikasjon. Den tønformulerbare biokompatible, partikulære virkestoffbæreren fremstilles helt eller til dels av lineære vannuoppløselige polysakkarider, fortrinnsvis poly(l,4-a-D-glukan), med homogen enhetlig størrelse fra fortrinnsvis biotransformatorisk fremstilling med evnen til å kluster- og/eller agglomeratdannelse. De derav resulterende fordeler benyttes fortrinnsvis i rammen av den tørre pulverinhaleringen.
NO20004980A 1998-04-09 2000-10-03 Partikulære varer av aktive ingredienser for den pulmonale anvendelsen NO20004980L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19816085 1998-04-09
PCT/EP1999/002385 WO1999052506A1 (de) 1998-04-09 1999-04-08 Partikulärer wirkstoffträger für die pulmonale applikation

Publications (2)

Publication Number Publication Date
NO20004980D0 NO20004980D0 (no) 2000-10-03
NO20004980L true NO20004980L (no) 2000-12-08

Family

ID=7864224

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20004980A NO20004980L (no) 1998-04-09 2000-10-03 Partikulære varer av aktive ingredienser for den pulmonale anvendelsen

Country Status (12)

Country Link
EP (1) EP1069889B1 (no)
JP (1) JP2002511399A (no)
KR (1) KR20010034755A (no)
CN (1) CN1423553A (no)
AT (1) ATE270097T1 (no)
AU (1) AU3421099A (no)
CA (1) CA2340340A1 (no)
DE (1) DE59909854D1 (no)
HU (1) HUP0101912A2 (no)
NO (1) NO20004980L (no)
PL (1) PL343342A1 (no)
WO (1) WO1999052506A1 (no)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19847593A1 (de) * 1998-10-15 2000-04-20 Aventis Res & Tech Gmbh & Co Zusammensetzung für die parenterale Applikation von Wirkstoffen
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
EP2280004B1 (en) 1999-06-29 2016-04-20 MannKind Corporation Pharmaceutical formulations comprising insulin complexed with a diketopiperazine
EP1494732B1 (en) 2002-03-20 2008-01-30 MannKind Corporation Inhalation apparatus
US20080090753A1 (en) 2004-03-12 2008-04-17 Biodel, Inc. Rapid Acting Injectable Insulin Compositions
DK1786784T3 (da) 2004-08-20 2011-02-14 Mannkind Corp Katalyse af diketopiperazinsyntese
CN104436170B (zh) 2004-08-23 2018-02-23 曼金德公司 用于药物输送的二酮哌嗪盐
AU2006290227B2 (en) 2005-09-14 2012-08-02 Mannkind Corporation Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents
US8084420B2 (en) 2005-09-29 2011-12-27 Biodel Inc. Rapid acting and long acting insulin combination formulations
KR20080096809A (ko) * 2006-02-22 2008-11-03 맨카인드 코포레이션 디케토피페라진 및 활성제를 포함하는 마이크로입자의 약학특성의 개선 방법
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
SG10201507036TA (en) 2008-06-13 2015-10-29 Mannkind Corp A dry powder inhaler and system for drug delivery
EP2609954B1 (en) 2008-06-20 2021-12-29 MannKind Corporation An interactive apparatus for real-time profiling of inhalation efforts
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
US9060927B2 (en) 2009-03-03 2015-06-23 Biodel Inc. Insulin formulations for rapid uptake
MX2011009512A (es) 2009-03-11 2011-11-29 Mannkind Corp Aparato, sistema y metodo para medir la resistencia de un inhalador.
MY172858A (en) 2009-06-12 2019-12-12 Mannkind Corp Diketopiperazine microparticles with defined isomer contents
MY157166A (en) 2009-06-12 2016-05-13 Mankind Corp Diketopiperazine microparticles with defined specific surface areas
CA2778698A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
IL223742A (en) 2010-06-21 2016-06-30 Mannkind Corp A dry powder inhaler and preparation for it
EP2694402B1 (en) 2011-04-01 2017-03-22 MannKind Corporation Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
HK1200318A1 (en) 2011-10-24 2015-08-07 曼金德公司 Methods and compositions for treating pain
EP2872205B1 (en) 2012-07-12 2017-02-08 MannKind Corporation Dry powder drug delivery systems
US10159644B2 (en) 2012-10-26 2018-12-25 Mannkind Corporation Inhalable vaccine compositions and methods
WO2014074797A1 (en) * 2012-11-09 2014-05-15 Civitas Therapeutics, Inc. Ultra low density pulmonary powders
WO2014144895A1 (en) 2013-03-15 2014-09-18 Mannkind Corporation Microcrystalline diketopiperazine compositions and methods
KR102465025B1 (ko) 2013-07-18 2022-11-09 맨카인드 코포레이션 열-안정성 건조 분말 약제학적 조성물 및 방법
EP3030294B1 (en) 2013-08-05 2020-10-07 MannKind Corporation Insufflation apparatus
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
WO2018222581A1 (en) * 2017-05-29 2018-12-06 Resinnate Therapeutics Llc Methods and formulations for administering beta glucan

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB937303A (en) * 1959-01-02 1963-09-18 Benger Lab Ltd Improvements in and relating to the application of drugs in finely divided condition
US6428771B1 (en) * 1995-05-15 2002-08-06 Pharmaceutical Discovery Corporation Method for drug delivery to the pulmonary system
GB9606188D0 (en) * 1996-03-23 1996-05-29 Danbiosyst Uk Pollysaccharide microspheres for the pulmonary delivery of drugs
DE19737481A1 (de) * 1997-08-28 1999-03-04 Hoechst Ag Sphärische lineare Polysaccharide enthaltende Mikropartikel

Also Published As

Publication number Publication date
EP1069889A1 (de) 2001-01-24
CN1423553A (zh) 2003-06-11
KR20010034755A (ko) 2001-04-25
EP1069889B1 (de) 2004-06-30
AU3421099A (en) 1999-11-01
CA2340340A1 (en) 1999-10-21
PL343342A1 (en) 2001-08-13
DE59909854D1 (de) 2004-08-05
WO1999052506B1 (de) 1999-11-25
HUP0101912A2 (hu) 2001-10-28
JP2002511399A (ja) 2002-04-16
ATE270097T1 (de) 2004-07-15
NO20004980D0 (no) 2000-10-03
WO1999052506A1 (de) 1999-10-21

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