NO20005081L - Et polypeptid som omfatter aminosyren fra et N-terminalt kolinbindende protein A trunkat, vaksine avledet derav og anvendelser derav - Google Patents

Et polypeptid som omfatter aminosyren fra et N-terminalt kolinbindende protein A trunkat, vaksine avledet derav og anvendelser derav

Info

Publication number
NO20005081L
NO20005081L NO20005081A NO20005081A NO20005081L NO 20005081 L NO20005081 L NO 20005081L NO 20005081 A NO20005081 A NO 20005081A NO 20005081 A NO20005081 A NO 20005081A NO 20005081 L NO20005081 L NO 20005081L
Authority
NO
Norway
Prior art keywords
amino acid
polypeptide
binding protein
choline binding
acid sequence
Prior art date
Application number
NO20005081A
Other languages
English (en)
Other versions
NO20005081D0 (no
Inventor
Elaine I Tuomanen
H Robert Masure
Theresa M Wizemann
Leslie Sydnor Johnson
Scott Koenig
Original Assignee
St Jude Childrens Res Hospital
Medimmune Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/056,019 external-priority patent/US6858706B2/en
Application filed by St Jude Childrens Res Hospital, Medimmune Inc filed Critical St Jude Childrens Res Hospital
Publication of NO20005081D0 publication Critical patent/NO20005081D0/no
Publication of NO20005081L publication Critical patent/NO20005081L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Oppfinnelsen frembringer et isolert polypeptid som omfatter en aminosyresekvens av et N-terminalt kolinbindende protein A trunkat hvori aminosyresekvensen er fremlagt i en. av SEQ ID NOS: 1, 3-7, eller 9-11, inklusive fragmenter, mutanter, varianter, analoger eller derivater derav. Videre frembringer denne oppfinnelse isolerte polypeptider som omfatter en aminosyresekvens av et N-terminalt kolinbindende protein A trunkat, hvori aminosyren er fremlagt i SEQ ID NO 24, hvori polypeptidet beholder sin opprinnelige tertiære struktur og fremgangsmåter til fremstilling. Denne oppfinnelse frembringer et". isolert polypeptid som omfatter en aminosyresekvens av et N-terminalt kolinbindende protein A trunkat, hvori polypeptidet har lektinaktivitet og ikke bindes til kolinet. Oppfinnelsen frembringer et isolert immunogent polypeptid som omfatter en aminosyresekvens for et N-terminalt kolinbindende protein A trunkat. Oppfinnelsen frembringer en isolert nukleinsyre som koder for et polypeptid som omfatter en aminosyresekvens for N-terminalt kolinbindende protein A trunkat. Endelig frembringer denne oppfinnelse farmasøytiske preparater, vaksiner og diagnostiske og terapeutiske fremgangsmåter til anvendelse.
NO20005081A 1998-04-07 2000-10-09 Et polypeptid som omfatter aminosyren fra et N-terminalt kolinbindende protein A trunkat, vaksine avledet derav og anvendelser derav NO20005081L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8087898P 1998-04-07 1998-04-07
US09/056,019 US6858706B2 (en) 1998-04-07 1998-04-07 Polypeptide comprising the amino acid of an N-terminal choline binding protein a truncate, vaccine derived therefrom and uses thereof
PCT/US1999/007669 WO1999051188A2 (en) 1998-04-07 1999-04-07 A polypeptide comprising the amino acid of an n-terminal choline binding protein a truncate, vaccine derived therefrom and uses thereof

Publications (2)

Publication Number Publication Date
NO20005081D0 NO20005081D0 (no) 2000-10-09
NO20005081L true NO20005081L (no) 2000-12-06

Family

ID=26734874

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20005081A NO20005081L (no) 1998-04-07 2000-10-09 Et polypeptid som omfatter aminosyren fra et N-terminalt kolinbindende protein A trunkat, vaksine avledet derav og anvendelser derav

Country Status (14)

Country Link
JP (1) JP4739521B2 (no)
KR (1) KR100638503B1 (no)
CN (1) CN1191851C (no)
AU (2) AU3479699A (no)
BR (1) BR9909910A (no)
CA (1) CA2326388C (no)
HU (1) HUP0102306A3 (no)
IL (1) IL138939A0 (no)
MX (1) MXPA00009899A (no)
NO (1) NO20005081L (no)
NZ (1) NZ507983A (no)
PL (1) PL193132B1 (no)
TR (1) TR200003498T2 (no)
WO (1) WO1999051188A2 (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0022742D0 (en) * 2000-09-15 2000-11-01 Smithkline Beecham Biolog Vaccine
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
GB0607088D0 (en) 2006-04-07 2006-05-17 Glaxosmithkline Biolog Sa Vaccine
JP5792920B2 (ja) 2005-12-22 2015-10-14 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム ワクチン
EA200901578A1 (ru) 2007-06-26 2010-08-30 Глаксосмитклайн Байолоджикалс С.А. Вакцина, содержащая конъюгаты капсульных полисахаридов streptococcus pneumoniae
KR20110009157A (ko) 2008-04-16 2011-01-27 글락소스미스클라인 바이오로지칼즈 에스.에이. 백신
GB201003924D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Immunogenic composition
KR20140033127A (ko) 2011-05-17 2014-03-17 글락소스미스클라인 바이오로지칼즈 에스.에이. 스트렙토코쿠스 뉴모니애에 대한 백신
GB201518684D0 (en) 2015-10-21 2015-12-02 Glaxosmithkline Biolog Sa Vaccine
GB201711635D0 (en) 2017-07-19 2017-08-30 Glaxosmithkline Biologicals Sa Immunogenic composition

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6592876B1 (en) * 1993-04-20 2003-07-15 Uab Research Foundation Pneumococcal genes, portions thereof, expression products therefrom, and uses of such genes, portions and products
WO1997041151A2 (en) * 1996-05-01 1997-11-06 The Rockefeller University Choline binding proteins for anti-pneumococcal vaccines
ATE348887T1 (de) * 1996-10-31 2007-01-15 Human Genome Sciences Inc Streptococcus pneumoniae antigene und impfstoffe
AU5355398A (en) * 1996-11-12 1998-06-03 Regents Of The University Of Minnesota C3 binding protein of (streptococcus pneumoniae)
US6858706B2 (en) * 1998-04-07 2005-02-22 St. Jude Children's Research Hospital Polypeptide comprising the amino acid of an N-terminal choline binding protein a truncate, vaccine derived therefrom and uses thereof
NZ530277A (en) * 1998-04-07 2005-08-26 Medimmune Inc Derivatives of pneumococcal choline binding proteins for vaccines

Also Published As

Publication number Publication date
IL138939A0 (en) 2001-11-25
MXPA00009899A (es) 2002-05-08
JP4739521B2 (ja) 2011-08-03
WO1999051188A2 (en) 1999-10-14
AU3479799A (en) 1999-10-25
HUP0102306A1 (hu) 2001-09-28
CN1191851C (zh) 2005-03-09
CN1342088A (zh) 2002-03-27
WO1999051188A3 (en) 2001-04-19
WO1999051188A9 (en) 2000-10-12
PL193132B1 (pl) 2007-01-31
BR9909910A (pt) 2002-01-15
CA2326388A1 (en) 1999-10-14
TR200003498T2 (tr) 2001-10-22
AU3479699A (en) 1999-10-25
NO20005081D0 (no) 2000-10-09
KR20010052244A (ko) 2001-06-25
HUP0102306A3 (en) 2008-04-28
JP2002516662A (ja) 2002-06-11
PL347946A1 (en) 2002-04-22
CA2326388C (en) 2014-02-04
KR100638503B1 (ko) 2006-10-26
NZ507983A (en) 2004-03-26
AU764811B2 (en) 2003-08-28

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FC2A Withdrawal, rejection or dismissal of laid open patent application