NO20005165L - Fremgangsmåte ved fremstilling av resin-bundne cykliske peptider - Google Patents

Fremgangsmåte ved fremstilling av resin-bundne cykliske peptider

Info

Publication number
NO20005165L
NO20005165L NO20005165A NO20005165A NO20005165L NO 20005165 L NO20005165 L NO 20005165L NO 20005165 A NO20005165 A NO 20005165A NO 20005165 A NO20005165 A NO 20005165A NO 20005165 L NO20005165 L NO 20005165L
Authority
NO
Norway
Prior art keywords
cyclic peptides
preparing resin
linked cyclic
linked
preparing
Prior art date
Application number
NO20005165A
Other languages
English (en)
Other versions
NO20005165D0 (no
Inventor
Adam W Sledeski
James J Mencel
Original Assignee
Aventis Pharm Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharm Prod Inc filed Critical Aventis Pharm Prod Inc
Publication of NO20005165D0 publication Critical patent/NO20005165D0/no
Publication of NO20005165L publication Critical patent/NO20005165L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02—Peptides being immobilised on, or in, an organic carrier
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06182—Dipeptides with the first amino acid being heterocyclic and Pristinamycin II; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO20005165A 1998-04-15 2000-10-13 Fremgangsmåte ved fremstilling av resin-bundne cykliske peptider NO20005165L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8189798P 1998-04-15 1998-04-15
PCT/US1999/008435 WO1999052933A1 (en) 1998-04-15 1999-04-15 Process for the preparation of resin-bound cyclic peptides

Publications (2)

Publication Number Publication Date
NO20005165D0 NO20005165D0 (no) 2000-10-13
NO20005165L true NO20005165L (no) 2000-12-15

Family

ID=22167111

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20005165A NO20005165L (no) 1998-04-15 2000-10-13 Fremgangsmåte ved fremstilling av resin-bundne cykliske peptider

Country Status (20)

Country Link
US (1) US6569993B1 (no)
EP (1) EP1093458A4 (no)
JP (1) JP2002511483A (no)
KR (1) KR20010085236A (no)
CN (2) CN1163504C (no)
AP (1) AP1117A (no)
AU (1) AU744812B2 (no)
BG (1) BG104903A (no)
BR (1) BR9909634A (no)
CA (1) CA2325572A1 (no)
CZ (1) CZ20003798A3 (no)
EA (1) EA200001071A1 (no)
HU (1) HUP0101629A2 (no)
IL (1) IL138338A0 (no)
NO (1) NO20005165L (no)
OA (1) OA11501A (no)
PL (1) PL347103A1 (no)
SK (1) SK15352000A3 (no)
UA (1) UA72460C2 (no)
WO (1) WO1999052933A1 (no)

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SK15352000A3 (sk) 1998-04-15 2001-04-09 Aventis Pharmaceuticals Products Inc. Spôsob výroby cyklických peptidov viazaných k polymérnemu nosiču
GB9912911D0 (en) * 1999-06-04 1999-08-04 Zeneca Ltd Chemical process
CN1432022A (zh) * 2000-04-19 2003-07-23 先灵公司 含有烷基和芳基丙氨酸p2部分的丙型肝炎病毒的大环ns3－丝氨酸蛋白酶抑制剂
US6756480B2 (en) 2000-04-27 2004-06-29 Amgen Inc. Modulators of receptors for parathyroid hormone and parathyroid hormone-related protein
US20040082783A1 (en) * 2002-08-06 2004-04-29 Schafmeister Christian E. Bis (amino acid) molecular scaffolds
PL1680443T3 (pl) 2003-11-05 2014-02-28 Dana Farber Cancer Inst Inc Stabilizowane alfa-helikalne peptydy i ich zastosowanie
GB0408958D0 (en) * 2004-04-22 2004-05-26 Pharma Mar Sa Convergent synthesis for kahalalide compounds
TW200626611A (en) * 2004-09-20 2006-08-01 Lonza Ag Peptide cyclisation
GB0505199D0 (en) * 2005-03-14 2005-04-20 Southampton Polypeptides Process
ATE469173T1 (de) 2006-10-13 2010-06-15 Lilly Co Eli Pegyliertes pth als pth-rezeptormodulatoren und ihre verwendung
CN101235080B (zh) * 2007-01-31 2010-09-08 中国科学院上海有机化学研究所 一种达托霉素的合成方法
CA2939778C (en) 2007-01-31 2019-01-29 Dana-Farber Cancer Institute, Inc. Stabilized p53 peptides and uses thereof
CA2682174C (en) 2007-03-28 2021-04-06 President And Fellows Of Harvard College Stitched polypeptides
EP2242503A4 (en) 2008-02-08 2012-04-25 Aileron Therapeutics Inc THERAPEUTIC PEPTIDOMIMETIC MACROCYCLES
US20110144303A1 (en) * 2008-04-08 2011-06-16 Aileron Therapeutics, Inc. Biologically Active Peptidomimetic Macrocycles
JP2012503025A (ja) 2008-09-22 2012-02-02 エルロン・セラピューティクス・インコーポレイテッド 精製されたポリペプチド組成物を調製するための方法
JP2012515172A (ja) 2009-01-14 2012-07-05 エルロン・セラピューティクス・インコーポレイテッド ペプチド模倣大環状分子
WO2011038049A1 (en) 2009-09-22 2011-03-31 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
KR20130099938A (ko) 2010-08-13 2013-09-06 에일러론 테라퓨틱스 인코포레이티드 펩티도미메틱 거대고리
CN104039342A (zh) 2011-10-18 2014-09-10 爱勒让治疗公司 拟肽大环化合物
HK1205454A1 (en) 2012-02-15 2015-12-18 Aileron Therapeutics, Inc. Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles
NZ627528A (en) 2012-02-15 2016-05-27 Aileron Therapeutics Inc Peptidomimetic macrocycles
SG11201503052RA (en) 2012-11-01 2015-05-28 Aileron Therapeutics Inc Disubstituted amino acids and methods of preparation and use thereof
MX389354B (es) 2014-09-24 2025-03-20 Aileron Therapeutics Inc Macrociclos peptidomimeticos y formulaciones de los mismos.
MX2017003797A (es) 2014-09-24 2017-06-15 Aileron Therapeutics Inc Macrociclos peptidomimeticos y usos de los mismos.
WO2016154058A1 (en) 2015-03-20 2016-09-29 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
CN106146648B (zh) * 2015-03-26 2020-06-12 深圳翰宇药业股份有限公司 一种甲状旁腺激素类似物的合成方法
WO2017004548A1 (en) 2015-07-01 2017-01-05 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
JP2018528217A (ja) 2015-09-10 2018-09-27 エルロン・セラピューティクス・インコーポレイテッドＡｉｌｅｒｏｎ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． Ｍｃｌ−１のモジュレーターとしてのペプチド模倣大環状分子
CN110551178B (zh) * 2018-06-01 2020-07-21 深圳翰宇药业股份有限公司 一种含脯氨酸的首尾环肽合成方法
CN112538103B (zh) * 2020-12-28 2022-10-25 合肥科生景肽生物科技有限公司 制备生长激素释放抑制素的方法

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DE3782010T2 (de) * 1986-12-04 1993-02-18 Toyo Jozo Kk Vom calcitonin-gen abgeleitete peptidderivate.
US5674839A (en) * 1987-05-22 1997-10-07 Competitive Technologies, Inc. Cyclic analogs of alpha-MSH fragments
US4959352A (en) * 1987-09-18 1990-09-25 Hoffmann-La Roche Inc. Cyclic growth hormone releasing factor analogs and method for the manufacture thereof
US5169862A (en) * 1989-07-07 1992-12-08 Peptide Technologies Corporation Analogs of viscosin and their uses
DK0452514T3 (da) * 1989-11-08 1995-08-21 Daicel Chem Peptid og fremgangsmåde til fremstilling af cyclisk peptid
US5064939A (en) * 1990-02-06 1991-11-12 The Salk Institute For Biological Studies Cyclic gnrh antagonists
US6183722B1 (en) * 1991-11-27 2001-02-06 Diatide, Inc. Somatostatin analogs
JPH0621079A (ja) 1992-06-29 1994-01-28 Nippon Telegr & Teleph Corp <Ntt> 半導体装置
US6008058A (en) * 1993-06-18 1999-12-28 University Of Louisville Cyclic peptide mixtures via side chain or backbone attachment and solid phase synthesis
GB2282813A (en) * 1993-10-15 1995-04-19 Merck & Co Inc Annular antigen scaffolds comprising thioether linkages
CA2126299C (en) * 1994-06-20 2000-12-12 Gordon E. Willick Parathyroid hormone analogues for the treatment of osteoporosis
US5569742A (en) * 1994-06-22 1996-10-29 The Salk Institute For Biological Studies Centrally truncated NPY cyclic peptides
US5717062A (en) * 1995-06-07 1998-02-10 Beth Israel Hospital Association Cyclic analogs of PTH and PTHrP
AU6311996A (en) * 1995-07-06 1997-02-05 Zeneca Limited Peptide inhibitors of fibronectine
US6169071B1 (en) * 1996-07-12 2001-01-02 Mcgill University Compounds and methods for modulating cell adhesion
EP0844252A3 (en) * 1996-11-15 1998-07-08 Remacle, José Cyclic peptides bearing a tail designed for subsequent chemical coupling and process for preparing same
CN1261281A (zh) * 1997-05-14 2000-07-26 罗纳·布朗克罗尔药制品有限公司 肽甲状旁腺激素类似物
AU2053699A (en) * 1997-12-15 1999-07-05 Peptor Ltd. Branched building units for synthesizing cyclic peptides
SK15352000A3 (sk) 1998-04-15 2001-04-09 Aventis Pharmaceuticals Products Inc. Spôsob výroby cyklických peptidov viazaných k polymérnemu nosiču

Also Published As

Publication number Publication date
CN1552737A (zh) 2004-12-08
CA2325572A1 (en) 1999-10-21
BG104903A (bg) 2001-07-31
CZ20003798A3 (cs) 2001-08-15
HUP0101629A2 (en) 2003-03-28
KR20010085236A (ko) 2001-09-07
AU3567999A (en) 1999-11-01
OA11501A (en) 2004-05-14
AP1117A (en) 2002-11-02
AU744812B2 (en) 2002-03-07
NO20005165D0 (no) 2000-10-13
EP1093458A1 (en) 2001-04-25
UA72460C2 (en) 2005-03-15
EA200001071A1 (ru) 2001-08-27
CN1163504C (zh) 2004-08-25
US6569993B1 (en) 2003-05-27
IL138338A0 (en) 2001-10-31
AP2000001972A0 (en) 2000-12-31
JP2002511483A (ja) 2002-04-16
CN1323313A (zh) 2001-11-21
WO1999052933A1 (en) 1999-10-21
BR9909634A (pt) 2001-10-16
SK15352000A3 (sk) 2001-04-09
PL347103A1 (en) 2002-03-25
EP1093458A4 (en) 2001-07-18

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