NO20005411D0 - Antipicornavirusforbindelser, deres fremstilling og anvendelse - Google Patents
Antipicornavirusforbindelser, deres fremstilling og anvendelseInfo
- Publication number
- NO20005411D0 NO20005411D0 NO20005411A NO20005411A NO20005411D0 NO 20005411 D0 NO20005411 D0 NO 20005411D0 NO 20005411 A NO20005411 A NO 20005411A NO 20005411 A NO20005411 A NO 20005411A NO 20005411 D0 NO20005411 D0 NO 20005411D0
- Authority
- NO
- Norway
- Prior art keywords
- antipicornavirus
- compounds
- preparation
- antipicornavirus compounds
- Prior art date
Links
- 230000001556 anti-picornavirus Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Crystallography & Structural Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8382898P | 1998-04-30 | 1998-04-30 | |
| US9835898P | 1998-08-28 | 1998-08-28 | |
| PCT/US1999/000260 WO1999057135A1 (en) | 1998-04-30 | 1999-01-05 | Antipicornaviral compounds, their preparation and use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20005411D0 true NO20005411D0 (no) | 2000-10-27 |
| NO20005411L NO20005411L (no) | 2000-10-27 |
Family
ID=26769788
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20005411A NO20005411L (no) | 1998-04-30 | 2000-10-27 | Antipicornavirusforbindelser, deres fremstilling og anvendelse |
Country Status (33)
| Country | Link |
|---|---|
| US (3) | US6531452B1 (no) |
| EP (1) | EP1073672B1 (no) |
| JP (1) | JP2003526600A (no) |
| KR (1) | KR20010043004A (no) |
| CN (1) | CN1198838C (no) |
| AP (1) | AP2000001934A0 (no) |
| AT (2) | ATE308557T1 (no) |
| AU (1) | AU768539B2 (no) |
| BG (1) | BG104899A (no) |
| BR (1) | BR9910573A (no) |
| CA (1) | CA2326763A1 (no) |
| DE (2) | DE69910762T2 (no) |
| DK (1) | DK1073672T3 (no) |
| EA (1) | EA003856B1 (no) |
| EE (1) | EE200000621A (no) |
| ES (1) | ES2205760T3 (no) |
| GE (1) | GEP20022824B (no) |
| HR (1) | HRP20000623A2 (no) |
| HU (1) | HUP0400624A2 (no) |
| IL (1) | IL138609A0 (no) |
| IS (1) | IS5633A (no) |
| LT (1) | LT4846B (no) |
| LV (1) | LV12666B (no) |
| NO (1) | NO20005411L (no) |
| NZ (1) | NZ507633A (no) |
| OA (1) | OA11503A (no) |
| PL (1) | PL351250A1 (no) |
| PT (1) | PT1073672E (no) |
| SI (1) | SI20428A (no) |
| SK (1) | SK284714B6 (no) |
| TR (1) | TR200003159T2 (no) |
| WO (1) | WO1999057135A1 (no) |
| YU (1) | YU66000A (no) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1073672T3 (da) | 1998-04-30 | 2003-12-08 | Agouron Pharma | Antipicornavirale forbindelser, deres fremstilling og anvendelse |
| US6774243B2 (en) | 1999-08-24 | 2004-08-10 | Agouron Pharmaceuticals, Inc. | Efficient synthetic routes for the preparation of rhinovirus protease inhibitors and key intermediates |
| US6355807B1 (en) | 1999-08-24 | 2002-03-12 | Agouron Pharmaceuticals, Inc. | Efficient synthetic routes for the preparation of rhinovirus protease inhibitors and key intermediates |
| PE20010517A1 (es) * | 1999-08-24 | 2001-05-16 | Agouron Pharma | Las rutas sinteticas eficientes para la preparacion de los inhibidores de la proteasa del rinovirus y los intermedios claves |
| PE20020157A1 (es) * | 1999-12-03 | 2002-02-22 | Agouron Pharma | Compuestos derivados de piridona como inhibidores de proteasas de picornaviral 3c, composiciones, sus usos farmaceuticos y materiales para su sintesis |
| PE20011277A1 (es) | 2000-04-14 | 2002-01-07 | Agouron Pharma | Compuestos y composiciones antipicornavirales, sus usos farmaceuticos y los materiales para su sintesis |
| WO2001096297A2 (en) | 2000-06-14 | 2001-12-20 | Agouron Pharmaceuticals, Inc. | Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis |
| WO2004093860A1 (en) * | 2003-04-21 | 2004-11-04 | Pfizer Inc. | Inhibitors of sars related coronavirus proteinase |
| US20040235952A1 (en) * | 2003-05-05 | 2004-11-25 | Agouron Pharmaceuticals, Inc. | Inhibitors of severe acute respiratory syndrome (SARS) 3C-like proteinase |
| US7462594B2 (en) | 2003-12-31 | 2008-12-09 | Taigen Biotechnology Co., Ltd. | Peptide-like compounds that inhibit coronaviral 3CL and flaviviridae viral proteases |
| AU2004312547A1 (en) * | 2003-12-31 | 2005-07-21 | Taigen Biotechnology | Protease inhibitors |
| CN100363346C (zh) * | 2004-10-22 | 2008-01-23 | 清华大学 | 冠状病毒主蛋白酶的小分子抑制剂、制备方法及其应用 |
| US7893657B2 (en) * | 2006-12-19 | 2011-02-22 | Anand Kumar Chavakula | Multi-power charger and battery backup system |
| KR100891699B1 (ko) | 2007-04-10 | 2009-04-03 | 광주과학기술원 | 7-아미노-4-((ｓ)-3-(4-플루오로페닐)-2-((r)-3-메틸-2-(5-메틸이소옥사졸-3-카복사미도)부탄아미도)프로판아미도)-7-옥소-2-헵테노에이트 유도체, 이의 제조방법 및 이를 유효성분으로 함유하는 바이러스성 질환의 예방 및 치료용 약학적 조성물 |
| US7741327B2 (en) | 2008-04-16 | 2010-06-22 | Hoffmann-La Roche Inc. | Pyrrolidinone glucokinase activators |
| DK2288615T3 (en) | 2008-05-21 | 2017-09-04 | Genesis Tech Ltd | SELECTIVE CASPASE INHIBITORS AND APPLICATIONS THEREOF |
| US9045524B2 (en) | 2009-05-21 | 2015-06-02 | Novagenesis Foundation | Selective caspase inhibitors and uses thereof |
| US8178689B2 (en) | 2010-06-17 | 2012-05-15 | Hoffman-La Roche Inc. | Tricyclic compounds |
| EP2697246B1 (en) * | 2011-04-15 | 2018-03-07 | Genesis Technologies Limited | Selective cysteine protease inhibitors and uses thereof |
| CN102838523A (zh) * | 2011-06-23 | 2012-12-26 | 南开大学 | 抗肠病毒71(ev71)戊内酰胺类化合物及其制备方法和用途 |
| CN103145608B (zh) * | 2011-12-07 | 2015-09-02 | 南开大学 | 抗肠病毒71(ev71)己内酰胺类化合物及其制备方法和用途 |
| RU2518314C2 (ru) * | 2012-08-30 | 2014-06-10 | Общество С Ограниченной Ответственностью "Фарминтерпрайсез" | Способ и средство активации irf-3 для лечения и профилактики заболеваний, вызываемых (+) phk-содержащими вирусами |
| CN110105348A (zh) * | 2019-03-08 | 2019-08-09 | 南开大学 | 新型迈克尔受体类肠病毒71型抑制剂的制备及用途 |
| EA202193251A1 (ru) * | 2019-06-05 | 2022-03-10 | Эмори Юниверсити | Пептидомиметики для лечения коронавирусной и пикорнавирусной инфекций |
| EP4114384A1 (en) | 2020-03-06 | 2023-01-11 | Pfizer Inc. | Methods of inhibiting sars-cov-2 replication and treating coronavirus disease 2019 |
| MX2022011370A (es) * | 2020-03-23 | 2022-10-07 | John M H Gregg | Compuestos antivirales y metodos para la administracion de los mismos. |
| WO2022156692A1 (zh) * | 2021-01-22 | 2022-07-28 | 中国人民解放军军事科学院军事医学研究院 | 一种环肽类病毒蛋白酶抑制剂，其制备方法，及其在抗病毒药物中的应用 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4652676A (en) | 1985-05-06 | 1987-03-24 | General Foods Corporation | L-aminodicarboxylic acid alkenes |
| EP0668870A1 (en) | 1991-06-14 | 1995-08-30 | Chiron Corporation | Inhibitors of picornavirus proteases |
| US5374623A (en) | 1992-08-20 | 1994-12-20 | Prototek, Inc. | Cysteine protease inhibitors effective for in vivo use |
| US5514778A (en) | 1993-07-01 | 1996-05-07 | Eli Lilly And Company | Anti-picornaviral agents |
| US5486623A (en) | 1993-12-08 | 1996-01-23 | Prototek, Inc. | Cysteine protease inhibitors containing heterocyclic leaving groups |
| IL112759A0 (en) | 1994-02-25 | 1995-05-26 | Khepri Pharmaceuticals Inc | Novel cysteine protease inhibitors |
| IT1269511B (it) | 1994-05-17 | 1997-04-01 | Univ Degli Studi Milano | Derivati di acidi ammino-solfonici , loro impiego nella sintesi di pseudopeptidi e procedimento per la loro preparazione |
| US5498616A (en) * | 1994-11-04 | 1996-03-12 | Cephalon, Inc. | Cysteine protease and serine protease inhibitors |
| IT1281031B1 (it) | 1995-11-17 | 1998-02-11 | Carlo Chiaves | Struttura prefabbricata per la realizzazione di opere costruite a cielo aperto, particolarmente per cavalcavia autostradali, |
| IL120310A (en) | 1996-03-01 | 2002-02-10 | Akzo Nobel Nv | Serine protease inhibitors and pharmaceuticals containing them |
| ES2242225T3 (es) * | 1996-05-14 | 2005-11-01 | Agouron Pharmaceuticals, Inc. | Inhibidores de proteasas 3c antipicornavirales y procedimientos correspondientes de utilizacion y de preparacion. |
| US5856530A (en) | 1996-05-14 | 1999-01-05 | Agouron Pharmaceuticals, Inc. | Antipicornaviral compounds and methods for their use and preparation |
| WO1997049668A1 (en) | 1996-06-13 | 1997-12-31 | Smithkline Beecham Corporation | Inhibitiors of cysteine protease |
| PT975588E (pt) * | 1997-03-28 | 2004-02-27 | Agouron Pharma | Compostos antipicornavirais, composicoes que os contem e metodos para a sua utilizacao |
| US6020371A (en) | 1997-03-28 | 2000-02-01 | Agouron Pharmaceuticals, Inc. | Antipicornaviral compounds compositions containing them and methods for their use |
| US6331554B1 (en) * | 1997-03-28 | 2001-12-18 | Agouron Pharmaceuticals, Inc. | Antipicornaviral compounds, compositions containing them, and methods for their use |
| US5962487A (en) | 1997-12-16 | 1999-10-05 | Agouron Pharmaceuticals, Inc. | Antipicornaviral compounds and methods for their use and preparation |
| DK1073672T3 (da) | 1998-04-30 | 2003-12-08 | Agouron Pharma | Antipicornavirale forbindelser, deres fremstilling og anvendelse |
| US6369226B1 (en) | 1999-06-21 | 2002-04-09 | Agouron Pharmaceuticals, Inc. | Substituted benzamide inhibitors of rhinovirus 3C protease |
| AU779321B2 (en) | 1999-08-04 | 2005-01-20 | Agouron Pharmaceuticals, Inc. | Antipicornaviral compounds and compositions, their pharmaceutical uses, and materials for their synthesis |
| PE20010517A1 (es) | 1999-08-24 | 2001-05-16 | Agouron Pharma | Las rutas sinteticas eficientes para la preparacion de los inhibidores de la proteasa del rinovirus y los intermedios claves |
| AU778062B2 (en) | 1999-08-24 | 2004-11-11 | Agouron Pharmaceuticals, Inc. | Process and intermediates for the preparation of isoxazolecaroxamides and analogues |
| PE20020157A1 (es) | 1999-12-03 | 2002-02-22 | Agouron Pharma | Compuestos derivados de piridona como inhibidores de proteasas de picornaviral 3c, composiciones, sus usos farmaceuticos y materiales para su sintesis |
-
1999
- 1999-01-05 DK DK99900780T patent/DK1073672T3/da active
- 1999-01-05 LT LT2000109A patent/LT4846B/lt not_active IP Right Cessation
- 1999-01-05 DE DE69910762T patent/DE69910762T2/de not_active Expired - Fee Related
- 1999-01-05 AP APAP/P/2000/001934A patent/AP2000001934A0/en unknown
- 1999-01-05 NZ NZ507633A patent/NZ507633A/en unknown
- 1999-01-05 PT PT99900780T patent/PT1073672E/pt unknown
- 1999-01-05 YU YU66000A patent/YU66000A/sh unknown
- 1999-01-05 IL IL13860999A patent/IL138609A0/xx unknown
- 1999-01-05 EA EA200001133A patent/EA003856B1/ru not_active IP Right Cessation
- 1999-01-05 WO PCT/US1999/000260 patent/WO1999057135A1/en not_active Ceased
- 1999-01-05 AU AU20287/99A patent/AU768539B2/en not_active Ceased
- 1999-01-05 SI SI9920041A patent/SI20428A/sl not_active IP Right Cessation
- 1999-01-05 DE DE69928140T patent/DE69928140D1/de not_active Expired - Lifetime
- 1999-01-05 CA CA002326763A patent/CA2326763A1/en not_active Abandoned
- 1999-01-05 KR KR1020007011851A patent/KR20010043004A/ko not_active Ceased
- 1999-01-05 GE GEAP19995606A patent/GEP20022824B/en unknown
- 1999-01-05 HR HR20000623A patent/HRP20000623A2/hr not_active Application Discontinuation
- 1999-01-05 ES ES99900780T patent/ES2205760T3/es not_active Expired - Lifetime
- 1999-01-05 AT AT03009409T patent/ATE308557T1/de not_active IP Right Cessation
- 1999-01-05 AT AT99900780T patent/ATE248186T1/de not_active IP Right Cessation
- 1999-01-05 EE EEP200000621A patent/EE200000621A/xx unknown
- 1999-01-05 PL PL99351250A patent/PL351250A1/xx not_active Application Discontinuation
- 1999-01-05 CN CNB998056278A patent/CN1198838C/zh not_active Expired - Fee Related
- 1999-01-05 TR TR2000/03159T patent/TR200003159T2/xx unknown
- 1999-01-05 SK SK1604-2000A patent/SK284714B6/sk unknown
- 1999-01-05 EP EP99900780A patent/EP1073672B1/en not_active Expired - Lifetime
- 1999-01-05 JP JP2000547104A patent/JP2003526600A/ja not_active Withdrawn
- 1999-01-05 HU HU0400624A patent/HUP0400624A2/hu unknown
- 1999-01-05 BR BR9910573-0A patent/BR9910573A/pt not_active IP Right Cessation
- 1999-04-29 US US09/301,977 patent/US6531452B1/en not_active Expired - Fee Related
-
2000
- 2000-09-22 IS IS5633A patent/IS5633A/is unknown
- 2000-10-20 OA OA1200000288A patent/OA11503A/en unknown
- 2000-10-27 NO NO20005411A patent/NO20005411L/no not_active Application Discontinuation
- 2000-11-01 BG BG104899A patent/BG104899A/xx unknown
- 2000-12-19 LV LV000162A patent/LV12666B/xx unknown
-
2002
- 2002-11-06 US US10/289,982 patent/US6995142B2/en not_active Expired - Fee Related
-
2005
- 2005-08-24 US US11/210,717 patent/US20060046966A1/en not_active Abandoned
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