NO20023823L - Fremgangsmåte for tilvirkning og bruk av pyrrolopyrimidinon- derivater - Google Patents

Fremgangsmåte for tilvirkning og bruk av pyrrolopyrimidinon- derivater

Info

Publication number: NO20023823L
Authority: NO; Norway
Prior art keywords: sub; sup; cycloalkyl; optionally substituted; fluoro atoms
Prior art date: 2000-02-17

Application number

NO20023823A

Other languages

English (en)

Other versions

NO20023823D0 (no

NO323553B1 (no

Inventor

Dae-Kee Kim

Ju Young Lee

Do Hyun Ryu

Nam Kyu Lee

Suk Ho Lee

Nam-Ho Kim

Jae-Sun Kim

Je Ho Ryu

Jin-Young Choi

Guang-Jin Im

Won-Son Choi

Tae Kon Kim

Hoon Cha

Original Assignee

In2Gen Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-02-17

Filing date

2002-08-13

Publication date

2002-10-09

2002-08-13 Application filed by In2Gen Co Ltd filed Critical In2Gen Co Ltd

2002-08-13 Publication of NO20023823D0 publication Critical patent/NO20023823D0/no

2002-10-09 Publication of NO20023823L publication Critical patent/NO20023823L/no

2007-06-11 Publication of NO323553B1 publication Critical patent/NO323553B1/no

Links

DXVAQZJPPDWTNY-UHFFFAOYSA-N pyrrolo[3,2-d]pyrimidin-2-one Chemical class O=C1N=CC2=NC=CC2=N1 DXVAQZJPPDWTNY-UHFFFAOYSA-N 0.000 title abstract 2
238000004519 manufacturing process Methods 0.000 title 1
238000000034 method Methods 0.000 title 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 7
125000000217 alkyl group Chemical group 0.000 abstract 5
125000001153 fluoro group Chemical group F* 0.000 abstract 5
125000003342 alkenyl group Chemical group 0.000 abstract 3
125000000304 alkynyl group Chemical group 0.000 abstract 3
125000003545 alkoxy group Chemical group 0.000 abstract 2
125000005843 halogen group Chemical group 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cardiology (AREA)
Pulmonology (AREA)
Heart & Thoracic Surgery (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Ophthalmology & Optometry (AREA)
Urology & Nephrology (AREA)
Gynecology & Obstetrics (AREA)
Otolaryngology (AREA)
Rheumatology (AREA)
Immunology (AREA)
Pain & Pain Management (AREA)
Pregnancy & Childbirth (AREA)
Hospice & Palliative Care (AREA)
Vascular Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrrole Compounds (AREA)

NO20023823A 2000-02-17 2002-08-13 Fremgangsmate for tilvirkning og bruk av pyrrolopyrimidinon-derivater NO323553B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
KR20000007625A KR100358083B1 (ko)	2000-02-17	2000-02-17	피롤로피리미디논 유도체와 이의 제조방법, 그리고 이의용도
PCT/KR2001/000227 WO2001060825A1 (en)	2000-02-17	2001-02-15	Pyrrolopyrimidinone derivatives, process of preparation and use

Publications (3)

Publication Number	Publication Date
NO20023823D0 NO20023823D0 (no)	2002-08-13
NO20023823L true NO20023823L (no)	2002-10-09
NO323553B1 NO323553B1 (no)	2007-06-11

Family

ID=19647449

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20023823A NO323553B1 (no)	2000-02-17	2002-08-13	Fremgangsmate for tilvirkning og bruk av pyrrolopyrimidinon-derivater

Country Status (23)

Country	Link
US (1)	US6962911B2 (no)
EP (1)	EP1257553B1 (no)
JP (1)	JP4845076B2 (no)
KR (1)	KR100358083B1 (no)
CN (1)	CN1312153C (no)
AT (1)	ATE267829T1 (no)
AU (2)	AU2001236140B9 (no)
BR (1)	BRPI0108395B8 (no)
CA (1)	CA2400268C (no)
DE (1)	DE60103508T2 (no)
DK (1)	DK1257553T3 (no)
ES (1)	ES2222344T3 (no)
HU (1)	HU230344B1 (no)
IL (2)	IL151234A0 (no)
MX (1)	MXPA02007942A (no)
NO (1)	NO323553B1 (no)
NZ (1)	NZ520842A (no)
PL (1)	PL210796B1 (no)
PT (1)	PT1257553E (no)
RU (1)	RU2263676C2 (no)
TR (1)	TR200402101T4 (no)
WO (1)	WO2001060825A1 (no)
ZA (1)	ZA200206587B (no)

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EP1362858A1 (en) *	2002-05-15	2003-11-19	SK Chemicals Co., Ltd.	Pyrrolopyrimidinone derivates, process of preparation and use
DE10229778A1 (de) *	2002-07-03	2004-01-29	Bayer Ag	Neue Verwendung von Imidazotriazinonen
FR2842809A1 (fr) *	2002-07-26	2004-01-30	Greenpharma Sas	NOUVELLES PYRAZOLO[1,5-a]-1,3,5-TRIAZINES SUBSTITUEES ET LEURS ANALOGUES, COMPOSITIONS PHARMACEUTIQUES LES CONTENANT, UTILISATION A TITRE DE MEDICAMENT ET PROCEDES POUR LEUR PREPARATION
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TW200745106A (en) *	2005-10-03	2007-12-16	Astrazeneca Ab	Chemical compounds
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KR20080003599A (ko) *	2006-07-03	2008-01-08	에스케이케미칼주식회사	피롤로피리미디논 유도체의 겐티세이트 염 및 이의제조방법
KR101002490B1 (ko) *	2007-06-09	2010-12-17	동아제약주식회사	유데나필을 유효성분으로 함유하는 만성 심부전증 치료용약학적 조성물
NZ599290A (en)	2009-10-16	2014-10-31	Melinta Therapeutics Inc	Antimicrobial compounds and methods of making and using the same
EA201270566A1 (ru)	2009-10-16	2012-11-30	Риб-Экс Фармасьютикалз, Инк.	Противомикробные соединения и способы их получения и применения
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CN102970965A (zh)	2010-04-05	2013-03-13	Sk化学公司	含有pde5抑制剂的减少皮肤皱纹的合成物
CN102372730B (zh) *	2010-08-19	2014-03-26	山东轩竹医药科技有限公司	桥环取代的磷酸二酯酶抑制剂
CN102134242B (zh) *	2011-01-21	2013-08-28	浙江大德药业集团有限公司	一种用于治疗阳痿的快速长效的化合物
TWI490220B (zh) *	2011-04-04	2015-07-01	Sk Chemicals Co Ltd	包含ｐｄｅ５抑制劑之用於減少皮膚皺紋之組成物
MY173518A (en) *	2011-04-15	2020-01-30	Melinta Therapeutics Inc	Antimicrobial compounds and methods of making and using the same
CN103826638B (zh)	2011-09-09	2015-11-25	Sk化学公司	含有pde5 抑制剂的减少皮肤皱纹的组合物
US9750743B2 (en)	2012-12-04	2017-09-05	Aribio Inc.	Composition comprising phosphodiesterase type 5 inhibitor for inhibiting apoptosis of nerve cells
CA2923214A1 (en)	2013-09-09	2015-03-12	Melinta Therapeutics, Inc.	Antimicrobial compounds and methods of making and using the same
EP3038623A4 (en)	2013-09-09	2017-04-19	Melinta Therapeutics, Inc.	Antimicrobial compounds and methods of making and using the same
HK1249758A1 (zh)	2015-03-11	2018-11-09	Melinta Therapeutics, Inc.	抗微生物化合物及其制备和使用方法
CN104744478B (zh) *	2015-03-20	2016-08-24	中国人民解放军第二军医大学	一种防治辐射损伤的化合物、单晶及其制备方法和应用
PL3377495T3 (pl)	2015-11-16	2022-05-16	Topadur Pharma Ag	Pochodne 2-fenylo-3,4-dihydropirolo[2,1-f] [1,2,4]triazynonu jako inhibitory fosfodiesterazy i ich zastosowania
US11098047B2 (en)	2016-05-06	2021-08-24	BioVersys AG	Antimicrobials and methods of making and using same
KR102670626B1 (ko) *	2017-05-22	2024-05-29	토파두르 파마 아게	가용성 구아닐레이트 사이클라제 활성제 및 포스포디에스테라제 억제제의 신규한 이중 작용 방식 및 이의 용도
JP7596257B2 (ja) *	2018-08-06	2024-12-09	ニコックスエス．エー．	一酸化窒素放出性ホスホジエステラーゼ５型阻害薬
WO2020109354A1 (en)	2018-11-28	2020-06-04	Topadur Pharma Ag	Novel dual mode of action soluble guanylate cyclase activators and phosphodiesterase inhibitors and uses thereof
KR102271305B1 (ko)	2020-05-21	2021-06-30	주식회사 아리바이오	치매 예방 및 치료용 조성물
WO2021245192A1 (en)	2020-06-04	2021-12-09	Topadur Pharma Ag	Novel dual mode of action soluble guanylate cyclase activators and phosphodiesterase inhibitors and uses thereof
KR102900330B1 (ko) *	2020-07-16	2025-12-15	제이투에이치바이오텍 (주)	이중 억제제 화합물 및 이들의 의약 용도
CN111825593B (zh) *	2020-08-19	2023-04-07	上海成澄科技有限公司	3-氨基吡咯-2-甲酰胺类化合物的合成方法
KR102272907B1 (ko)	2020-11-05	2021-07-05	주식회사 아리바이오	치매 예방 및 치료용 조성물
KR102272910B1 (ko)	2021-01-28	2021-07-06	주식회사 아리바이오	당뇨병을 동반한 치매 예방 및 치료용 조성물
KR20220140960A (ko)	2021-04-12	2022-10-19	주식회사 아리바이오	당뇨병을 동반한 치매 예방 및 치료용 조성물
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KR20220146095A (ko)	2021-04-23	2022-11-01	주식회사 아리바이오	Pde5 억제제와 글루코코르티코이드 수용체 길항제 병용투여를 통한 치매 예방 및 치료용 조성물
CA3228160A1 (en)	2021-09-29	2023-04-06	Topadur Pharma Ag	Topical compositions of 2-phenyl-3,4-dihydropyrrolo[2,l-f] [1,2,4]triazinone derivatives and uses thereof
JP2025506878A (ja)	2022-03-02	2025-03-13	トパデュールファルマアーゲー	局所組成物及びその使用
KR20230129639A (ko)	2022-03-02	2023-09-11	연세대학교 산학협력단	이중작용 pde5 억제제/질산유기에스터의 국소 혈류 증진을 위한 경피 투약 형태
KR20240117491A (ko)	2023-01-25	2024-08-01	주식회사 아리바이오	포스포디에스테라제 타입 ５ 저해제를 유효성분으로 포함하는 외상 후 스트레스 장애의 예방 또는 치료용 조성물

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2000
- 2000-02-17 KR KR20000007625A patent/KR100358083B1/ko not_active Expired - Lifetime
2001
- 2001-02-15 AU AU2001236140A patent/AU2001236140B9/en not_active Expired
- 2001-02-15 DE DE60103508T patent/DE60103508T2/de not_active Expired - Lifetime
- 2001-02-15 MX MXPA02007942A patent/MXPA02007942A/es active IP Right Grant
- 2001-02-15 NZ NZ520842A patent/NZ520842A/en not_active IP Right Cessation
- 2001-02-15 IL IL15123401A patent/IL151234A0/xx unknown
- 2001-02-15 DK DK01908397T patent/DK1257553T3/da active
- 2001-02-15 AT AT01908397T patent/ATE267829T1/de active
- 2001-02-15 PL PL358188A patent/PL210796B1/pl unknown
- 2001-02-15 WO PCT/KR2001/000227 patent/WO2001060825A1/en not_active Ceased
- 2001-02-15 US US10/204,327 patent/US6962911B2/en not_active Expired - Lifetime
- 2001-02-15 RU RU2002124872/04A patent/RU2263676C2/ru active
- 2001-02-15 JP JP2001560209A patent/JP4845076B2/ja not_active Expired - Lifetime
- 2001-02-15 ES ES01908397T patent/ES2222344T3/es not_active Expired - Lifetime
- 2001-02-15 EP EP01908397A patent/EP1257553B1/en not_active Expired - Lifetime
- 2001-02-15 PT PT01908397T patent/PT1257553E/pt unknown
- 2001-02-15 CA CA002400268A patent/CA2400268C/en not_active Expired - Lifetime
- 2001-02-15 AU AU3614001A patent/AU3614001A/xx active Pending
- 2001-02-15 CN CNB018075002A patent/CN1312153C/zh not_active Expired - Lifetime
- 2001-02-15 TR TR2004/02101T patent/TR200402101T4/xx unknown
- 2001-02-15 BR BRPI0108395A patent/BRPI0108395B8/pt not_active IP Right Cessation
- 2001-02-15 HU HU0300527A patent/HU230344B1/hu unknown
2002
- 2002-08-13 NO NO20023823A patent/NO323553B1/no not_active IP Right Cessation
- 2002-08-13 IL IL151234A patent/IL151234A/en active IP Right Grant
- 2002-08-16 ZA ZA200206587A patent/ZA200206587B/xx unknown

Also Published As

Publication number	Publication date
ATE267829T1 (de)	2004-06-15
EP1257553A1 (en)	2002-11-20
DK1257553T3 (da)	2004-10-04
NO20023823D0 (no)	2002-08-13
PL358188A1 (en)	2004-08-09
IL151234A0 (en)	2003-04-10
PL210796B1 (pl)	2012-03-30
RU2263676C2 (ru)	2005-11-10
DE60103508D1 (de)	2004-07-01
AU2001236140B9 (en)	2006-08-31
RU2002124872A (ru)	2004-01-10
AU3614001A (en)	2001-08-27
HU230344B1 (hu)	2016-02-29
US20030171361A1 (en)	2003-09-11
JP2003523344A (ja)	2003-08-05
KR20010083637A (ko)	2001-09-01
WO2001060825A1 (en)	2001-08-23
AU2001236140B2 (en)	2006-01-12
HUP0300527A3 (en)	2012-10-29
DE60103508T2 (de)	2005-06-30
BRPI0108395B1 (pt)	2017-06-06
KR100358083B1 (ko)	2002-10-25
BR0108395A (pt)	2003-03-11
BRPI0108395B8 (pt)	2021-05-25
EP1257553B1 (en)	2004-05-26
ES2222344T3 (es)	2005-02-01
NO323553B1 (no)	2007-06-11
CA2400268A1 (en)	2001-08-23
CN1312153C (zh)	2007-04-25
HUP0300527A2 (hu)	2003-07-28
NZ520842A (en)	2004-04-30
MXPA02007942A (es)	2004-09-10
IL151234A (en)	2010-05-17
US6962911B2 (en)	2005-11-08
TR200402101T4 (tr)	2004-10-21
ZA200206587B (en)	2003-10-09
PT1257553E (pt)	2004-10-29
CA2400268C (en)	2009-08-18
JP4845076B2 (ja)	2011-12-28
CN1422271A (zh)	2003-06-04

Legal Events

Date	Code	Title	Description
2021-03-08	MK1K	Patent expired

Publication	Publication Date	Title
NO20023823D0 (no)	2002-08-13	Fremgangsmåte for tilvirkning og bruk av pyrrolopyrimidinon- derivater
BE2018C008I2 (no)	2021-02-04
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WO2001077107A8 (en)	2003-02-13	Oxazole derivatives and their uses as tyrosine kinase inhibitors
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CY1106247T1 (el)	2011-06-08	Θειοφαινο- και θειαζολοσουλφοναμιδες ως αντινεοπλαστικοι παραγοντες
DK0918776T3 (da)	2004-07-12	Totalsyntese af antitumor acylfulvener
AU3415599A (en)	1999-10-18	Benzoheterocyclic distamycin derivatives, process for preparing them, and their use as antitumor agents
NZ332923A (en)	2000-03-27	Distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents
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DE59106102D1 (de)	1995-09-07	Herbizide Sulfonylharnstoffe, Verfahren und Zwischenprodukte zu ihrer Herstellung.
ATE284379T1 (de)	2004-12-15	Aminderivate
ES483557A1 (es)	1980-04-16	Procedimiento para la preparacion de derivados de imidazol
TR200402333T4 (tr)	2004-12-21	Artropodisidal karboksanilidler
NO20026201D0 (no)	2002-12-23	Fremgangsmåte for fremstilling av 4-brom-anilin-derivater
HUP0004154A2 (hu)	2002-11-28	Eljárás 1,5-diszubsztituált-3-amino-1,2,4-triazolok előállítására
SE9901237D0 (sv)	1999-04-06	Novel use
PT1414812E (pt)	2006-05-31	Derivados do acido hidroxamico