NO20030593L - Fremgangsmater for behandling av cancer og smerten forbundet derved ved a anvende endotelinantagonister - Google Patents

Fremgangsmater for behandling av cancer og smerten forbundet derved ved a anvende endotelinantagonister

Info

Publication number: NO20030593L
Authority: NO; Norway
Prior art keywords: methods; associated therewith; treating cancer; pain associated; endothelin antagonists
Prior art date: 2000-08-07

Application number

NO20030593A

Other languages

English (en)

Norwegian (no)

Other versions

NO20030593D0 (no

Inventor

Todd J Janus

Robert J Padley

Original Assignee

Abbott Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-08-07

Filing date

2003-02-06

Publication date

2003-02-06

2003-02-06 Application filed by Abbott Lab filed Critical Abbott Lab

2003-02-06 Publication of NO20030593D0 publication Critical patent/NO20030593D0/no

2003-02-06 Publication of NO20030593L publication Critical patent/NO20030593L/no

Links

102000002045 Endothelin Human genes 0.000 title 1
108050009340 Endothelin Proteins 0.000 title 1
206010028980 Neoplasm Diseases 0.000 title 1
239000005557 antagonist Substances 0.000 title 1
201000011510 cancer Diseases 0.000 title 1
ZUBDGKVDJUIMQQ-UBFCDGJISA-N endothelin-1 Chemical compound C([C@@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(O)=O)NC(=O)[C@H]1NC(=O)[C@H](CC=2C=CC=CC=2)NC(=O)[C@@H](CC=2C=CC(O)=CC=2)NC(=O)[C@H](C(C)C)NC(=O)[C@H]2CSSC[C@@H](C(N[C@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N2)=O)NC(=O)[C@@H](CO)NC(=O)[C@H](N)CSSC1)C1=CNC=N1 ZUBDGKVDJUIMQQ-UBFCDGJISA-N 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P13/08—Drugs for disorders of the urinary system of the prostate
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- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P35/04—Antineoplastic agents specific for metastasis
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/28—Antiandrogens
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
- A—HUMAN NECESSITIES
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- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/34—Gestagens
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Physical Education & Sports Medicine (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Pain & Pain Management (AREA)
Surgery (AREA)
Reproductive Health (AREA)
Nutrition Science (AREA)
Hematology (AREA)
Obesity (AREA)
Urology & Nephrology (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Oncology (AREA)
Neurosurgery (AREA)
Gastroenterology & Hepatology (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

NO20030593A 2000-08-07 2003-02-06 Fremgangsmater for behandling av cancer og smerten forbundet derved ved a anvende endotelinantagonister NO20030593L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US63338900A	2000-08-07	2000-08-07
PCT/US2001/024716 WO2002011713A2 (en)	2000-08-07	2001-08-06	Methods of treating bone cancer and the pain associated therewith using endothelin antagonists

Publications (2)

Publication Number	Publication Date
NO20030593D0 NO20030593D0 (no)	2003-02-06
NO20030593L true NO20030593L (no)	2003-02-06

Family

ID=24539436

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20030593A NO20030593L (no)	2000-08-07	2003-02-06	Fremgangsmater for behandling av cancer og smerten forbundet derved ved a anvende endotelinantagonister

Country Status (22)

Country	Link
EP (1)	EP1347751B1 (pl)
JP (3)	JP4217068B2 (pl)
KR (1)	KR20030027007A (pl)
CN (1)	CN1635878A (pl)
AR (1)	AR031122A1 (pl)
AT (1)	ATE465728T1 (pl)
AU (2)	AU8113401A (pl)
BG (1)	BG107577A (pl)
BR (1)	BR0108865A (pl)
CA (1)	CA2416879C (pl)
DE (1)	DE60141979D1 (pl)
HU (1)	HUP0302977A2 (pl)
IL (1)	IL153769A0 (pl)
MX (1)	MXPA03000984A (pl)
NO (1)	NO20030593L (pl)
NZ (1)	NZ523562A (pl)
PE (1)	PE20020273A1 (pl)
PL (1)	PL366160A1 (pl)
SK (1)	SK1782003A3 (pl)
TW (1)	TWI306760B (pl)
WO (1)	WO2002011713A2 (pl)
ZA (1)	ZA200300253B (pl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0219660D0 (en)	2002-08-23	2002-10-02	Astrazeneca Ab	Therapeutic use
GB0403744D0 (en)	2004-02-20	2004-03-24	Astrazeneca Ab	Chemical process
CN101022826A (zh) *	2004-06-07	2007-08-22	哈罗尔·戴维·贡	用于癌症治疗的细菌组合物
US9107864B2 (en)	2004-06-07	2015-08-18	Qu Biologics Inc.	Tissue targeted antigenic activation of the immune response to treat cancers
CA2697057A1 (en)	2007-08-22	2009-02-26	Gilead Colorado, Inc.	Therapy for complications of diabetes
WO2011114103A1 (en)	2010-03-18	2011-09-22	Biolipox Ab	Pyrimidinones for use as medicaments
PL2598165T3 (pl)	2010-07-26	2018-02-28	Qu Biologics Inc.	Immunogenne kompozycje przeciwzapalne
CN102485238A (zh) *	2010-12-06	2012-06-06	陈炯华	芎芷镇痛方
CN106456740B (zh)	2014-05-02	2021-06-08	Qu生物制药公司	抗微生物免疫调节

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6063911A (en) *	1993-12-01	2000-05-16	Marine Polymer Technologies, Inc.	Methods and compositions for treatment of cell proliferative disorders
ES2259803T3 (es) *	1996-02-13	2006-10-16	Abbott Laboratories	Nuevos derivados de pirrolidina sustituidos con benzo-1,3-dioxolilo y benzofuranilo como antagonistas de endostelina.
HUP0003484A3 (en)	1997-08-04	2002-02-28	Abbott Lab	Pyrrolidine-3-crboxylic acid derivatives and their use as endothelin antagonists
WO2000036198A1 (en) *	1998-12-11	2000-06-22	Mactapes Limited	Curtain heading tape manufacture
US6545048B1 (en) *	1999-06-29	2003-04-08	California Institute Of Technology	Compositions and methods of treating cancer using compositions comprising an inhibitor or endothelin receptor activity

2001
- 2001-07-24 TW TW090118053A patent/TWI306760B/zh active
- 2001-08-06 CA CA002416879A patent/CA2416879C/en not_active Expired - Fee Related
- 2001-08-06 IL IL15376901A patent/IL153769A0/xx unknown
- 2001-08-06 KR KR10-2003-7001735A patent/KR20030027007A/ko not_active Ceased
- 2001-08-06 SK SK178-2003A patent/SK1782003A3/sk unknown
- 2001-08-06 EP EP01959595A patent/EP1347751B1/en not_active Expired - Lifetime
- 2001-08-06 MX MXPA03000984A patent/MXPA03000984A/es active IP Right Grant
- 2001-08-06 AT AT01959595T patent/ATE465728T1/de not_active IP Right Cessation
- 2001-08-06 HU HU0302977A patent/HUP0302977A2/hu unknown
- 2001-08-06 AU AU8113401A patent/AU8113401A/xx active Pending
- 2001-08-06 JP JP2002517050A patent/JP4217068B2/ja not_active Expired - Fee Related
- 2001-08-06 BR BR0108865-3A patent/BR0108865A/pt not_active Application Discontinuation
- 2001-08-06 NZ NZ523562A patent/NZ523562A/en unknown
- 2001-08-06 AU AU2001281134A patent/AU2001281134B2/en not_active Ceased
- 2001-08-06 PL PL01366160A patent/PL366160A1/pl unknown
- 2001-08-06 PE PE2001000782A patent/PE20020273A1/es not_active Application Discontinuation
- 2001-08-06 DE DE60141979T patent/DE60141979D1/de not_active Expired - Lifetime
- 2001-08-06 CN CNA018169929A patent/CN1635878A/zh active Pending
- 2001-08-06 WO PCT/US2001/024716 patent/WO2002011713A2/en not_active Ceased
- 2001-08-06 AR ARP010103755A patent/AR031122A1/es not_active Application Discontinuation
2003
- 2003-01-09 ZA ZA200300253A patent/ZA200300253B/en unknown
- 2003-02-06 NO NO20030593A patent/NO20030593L/no not_active Application Discontinuation
- 2003-02-21 BG BG107577A patent/BG107577A/bg unknown
2006
- 2006-11-08 JP JP2006302713A patent/JP2007084564A/ja active Pending
- 2006-11-08 JP JP2006302712A patent/JP2007063288A/ja active Pending

Also Published As

Publication number	Publication date
AR031122A1 (es)	2003-09-10
CA2416879A1 (en)	2002-02-14
HUP0302977A2 (hu)	2003-12-29
JP2007063288A (ja)	2007-03-15
JP2007084564A (ja)	2007-04-05
IL153769A0 (en)	2003-07-06
EP1347751B1 (en)	2010-04-28
BG107577A (bg)	2003-10-31
AU8113401A (en)	2002-02-18
KR20030027007A (ko)	2003-04-03
ZA200300253B (en)	2004-11-17
PE20020273A1 (es)	2002-04-16
MXPA03000984A (es)	2003-09-05
DE60141979D1 (de)	2010-06-10
SK1782003A3 (en)	2003-08-05
JP2004520266A (ja)	2004-07-08
WO2002011713A2 (en)	2002-02-14
NZ523562A (en)	2006-10-27
JP4217068B2 (ja)	2009-01-28
WO2002011713A3 (en)	2003-07-17
AU2001281134B2 (en)	2005-06-09
BR0108865A (pt)	2005-04-19
PL366160A1 (pl)	2005-01-24
CA2416879C (en)	2006-11-07
EP1347751A2 (en)	2003-10-01
TWI306760B (en)	2009-03-01
ATE465728T1 (de)	2010-05-15
NO20030593D0 (no)	2003-02-06
CN1635878A (zh)	2005-07-06

Legal Events

Date	Code	Title	Description
2011-01-17	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
GB0109537D0 (en)	2001-06-06	Well treatment fluids and methods for the use thereof
DK1604680T3 (da)	2010-05-10	Anvendelse af butulinumtoksin ved behandlingen af neuralgisk smerte
GB0028264D0 (en)	2001-01-03	Well treatment
GB0028269D0 (en)	2001-01-03	Well treatment
PT1267650E (pt)	2006-05-31	Tratamento do tabaco
GB0028429D0 (en)	2001-01-10	Therapy
AU7532601A (en)	2001-12-17	Materials and methods for the treatment of gastroesophageal reflux disease
NO20032122D0 (no)	2003-05-12	Forbedret behandling
NO20030593D0 (no)	2003-02-06	Fremgangsmåter for behandling av cancer og smerten forbundet derved ved å anvende endotelinantagonister
DK1317478T3 (da)	2007-05-07	Skelnen mellem GnRH-I og GnRH-II
ID30377A (id)	2001-11-29	Metoda pengobatan neurodegenerasi
GB0026015D0 (en)	2000-12-13	Cancer treatment
GB2372134B (en)	2004-01-28	Coin treating device
IL151871A0 (en)	2003-04-10	Restenosis treatment
GB2364078B (en)	2004-06-09	Ground treatment
GB0016693D0 (en)	2000-08-23	Cough treatment
AU6884801A (en)	2002-01-14	Therapeutic compounds and methods
GB2397430B (en)	2004-09-01	Coin treating device
GB0027780D0 (en)	2000-12-27	Treating cancer
FI20002229L (fi)	2002-04-10	Menetelmä selkäkivun hoitamiseksi
ZA200303696B (en)	2004-08-13	Applicator and stimulator device.
GB0009490D0 (en)	2000-06-07	Diamond treatment
GB0007321D0 (en)	2000-05-17	Arthritis treatment
GB0017495D0 (en)	2000-08-30	Treatment
GB0012793D0 (en)	2000-07-19	Treatment