NO20031179L - Chemokin-reseptorbindende heterocykliske forbindelser - Google Patents
Chemokin-reseptorbindende heterocykliske forbindelserInfo
- Publication number
- NO20031179L NO20031179L NO20031179A NO20031179A NO20031179L NO 20031179 L NO20031179 L NO 20031179L NO 20031179 A NO20031179 A NO 20031179A NO 20031179 A NO20031179 A NO 20031179A NO 20031179 L NO20031179 L NO 20031179L
- Authority
- NO
- Norway
- Prior art keywords
- receptor binding
- heterocyclic compounds
- chemokine receptor
- binding heterocyclic
- ccr5
- Prior art date
Links
- 102000009410 Chemokine receptor Human genes 0.000 title abstract 2
- 108050000299 Chemokine receptor Proteins 0.000 title abstract 2
- 150000002391 heterocyclic compounds Chemical class 0.000 title 1
- 102100035875 C-C chemokine receptor type 5 Human genes 0.000 abstract 1
- 101710149870 C-C chemokine receptor type 5 Proteins 0.000 abstract 1
- 102100031650 C-X-C chemokine receptor type 4 Human genes 0.000 abstract 1
- 101000922348 Homo sapiens C-X-C chemokine receptor type 4 Proteins 0.000 abstract 1
- -1 Tertiary amine compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- AIDS & HIV (AREA)
- Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23289100P | 2000-09-15 | 2000-09-15 | |
| US23451000P | 2000-09-22 | 2000-09-22 | |
| PCT/CA2001/001326 WO2002022600A2 (en) | 2000-09-15 | 2001-09-17 | Chemokine receptor binding heterocyclic compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20031179L true NO20031179L (no) | 2003-03-14 |
| NO20031179D0 NO20031179D0 (no) | 2003-03-14 |
Family
ID=26926422
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20031179A NO20031179D0 (no) | 2000-09-15 | 2003-03-14 | Chemokin-reseptorbindende heterocykliske forbindelser |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US6864265B2 (no) |
| EP (1) | EP1317445B1 (no) |
| JP (1) | JP2004508422A (no) |
| KR (1) | KR20030029998A (no) |
| CN (1) | CN1457339A (no) |
| AT (1) | ATE425157T1 (no) |
| AU (2) | AU2001291569B2 (no) |
| BR (1) | BR0113930A (no) |
| CA (1) | CA2419224A1 (no) |
| DE (1) | DE60137944D1 (no) |
| ES (1) | ES2325909T3 (no) |
| HK (1) | HK1052011A1 (no) |
| HU (1) | HUP0301093A2 (no) |
| IL (1) | IL154227A0 (no) |
| MX (1) | MXPA03002326A (no) |
| NO (1) | NO20031179D0 (no) |
| NZ (1) | NZ524420A (no) |
| PL (1) | PL360932A1 (no) |
| RU (1) | RU2289581C2 (no) |
| SG (1) | SG126007A1 (no) |
| TR (1) | TR200300322T2 (no) |
| WO (1) | WO2002022600A2 (no) |
Families Citing this family (68)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1752455B1 (en) | 2000-09-15 | 2010-11-10 | Anormed Inc. | Chemokine receptor binding heterocyclic compounds |
| CA2419224A1 (en) | 2000-09-15 | 2002-03-21 | Anormed Inc. | Chemokine receptor binding heterocyclic compounds |
| HUP0301094A2 (hu) * | 2000-09-15 | 2003-09-29 | Anormed Inc. | Kemonikinreceptorhoz kötżdż heterociklusos vegyületek, e vegyületeket tartalmazó gyógyászati készítmények és alkalmazásuk |
| US7169750B2 (en) | 2001-07-31 | 2007-01-30 | Anormed, Inc. | Methods to mobilize progenitor/stem cells |
| KR100996378B1 (ko) | 2001-07-31 | 2010-11-25 | 아노르메드 인코포레이티드 | 선조/줄기 세포를 이동시킴으로써 이식에 사용하기 위한 약제학적 조성물 |
| US7354932B2 (en) * | 2001-12-21 | 2008-04-08 | Anormed, Inc. | Chemokine receptor binding heterocyclic compounds with enhanced efficacy |
| HUP0402458A2 (hu) * | 2001-12-21 | 2005-07-28 | Anormed Inc. | Fokozott hatékonyságú kemokin receptor kötő heterociklusos vegyületek |
| US7176227B2 (en) | 2002-09-11 | 2007-02-13 | Kureha Corporation | Amine compounds and use thereof |
| US7504422B2 (en) | 2003-04-02 | 2009-03-17 | Taigen Biotechnology Co. Ltd. | Polyamine compounds |
| EP1608352B1 (en) | 2003-04-02 | 2009-12-30 | Taigen Biotechnology | Polyamine compounds for treating chemokine receptor mediated diseases |
| US7291631B2 (en) | 2003-04-11 | 2007-11-06 | Genzyme Corporation | CXCR4 chemokine receptor binding compounds |
| WO2004092169A1 (ja) * | 2003-04-18 | 2004-10-28 | Ono Pharmaceutical Co., Ltd. | スピロピペリジン化合物およびその医薬用途 |
| US7501518B2 (en) | 2003-04-22 | 2009-03-10 | Genzyme Corporation | Methods of making 2,6-diaryl piperidine derivatives |
| ES2393188T3 (es) | 2003-04-22 | 2012-12-19 | Genzyme Corporation | Compuestos heterocíclicos que se unen a los receptores de quimiocina y presentan eficacia mejorada |
| JP2007501189A (ja) * | 2003-08-01 | 2007-01-25 | ジェネラブス テクノロジーズ,インコーポレイテッド | フラビウイルス科に対する二環式イミダゾール誘導体 |
| CA2548393A1 (en) | 2003-12-11 | 2005-06-30 | Anormed Inc. | Chemokine receptor binding compounds |
| US7498346B2 (en) | 2003-12-11 | 2009-03-03 | Genzyme Corporation | Chemokine receptor binding compounds |
| CN1950343B (zh) * | 2004-03-10 | 2013-06-19 | 株式会社吴羽 | 胺系碱性化合物及其用途 |
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| AU2006280945A1 (en) | 2005-08-19 | 2007-02-22 | Genzyme Corporation | Methods to enhance chemotherapy |
| WO2007058322A1 (ja) | 2005-11-18 | 2007-05-24 | Ono Pharmaceutical Co., Ltd. | 塩基性基を含有する化合物およびその用途 |
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| WO2007115231A2 (en) * | 2006-03-30 | 2007-10-11 | Chemocentryx, Inc. | Cxcr4 modulators |
| US8618122B2 (en) | 2006-05-16 | 2013-12-31 | Ono Pharmaceutical Co., Ltd. | Compound having acidic group which may be protected, and use thereof |
| AU2007281090A1 (en) * | 2006-08-02 | 2008-02-07 | Genzyme Corporation | Combination therapy |
| CN101500595A (zh) * | 2006-08-07 | 2009-08-05 | 健赞股份有限公司 | 组合治疗 |
| WO2009036341A2 (en) * | 2007-09-14 | 2009-03-19 | The Regents Of The University Of Michigan | Compositions and methods relating to hiv protease inhibition |
| WO2010000633A1 (en) * | 2008-07-02 | 2010-01-07 | F. Hoffmann-La Roche Ag | Novel phenylpyrazinones as kinase inhibitors |
| US8354435B2 (en) * | 2008-09-08 | 2013-01-15 | The Board Of Trustees Of The Leland Stanford Junior University | Modulators of aldehyde dehydrogenase activity and methods of use thereof |
| AU2011336397B2 (en) | 2010-12-03 | 2016-12-15 | Emory University | Chemokine CXCR4 receptor modulators and uses related thereto |
| CN102603683B (zh) * | 2012-02-10 | 2014-04-09 | 山东大学 | 一种呋喃类化合物及其制备方法与应用 |
| CN104478795A (zh) * | 2014-11-24 | 2015-04-01 | 苏州乔纳森新材料科技有限公司 | 一种2-氯烟醛的制备方法 |
| CA3026154A1 (en) | 2015-06-03 | 2016-12-08 | The University Of Queensland | Mobilizing agents and uses therefor |
| CN104945313A (zh) * | 2015-06-19 | 2015-09-30 | 洪帅金 | 一种2-甲基-3-溴吡啶的制备方法 |
| NZ741093A (en) * | 2015-10-06 | 2022-12-23 | Proteostasis Therapeutics Inc | Compounds, compositions, and methods for modulating cftr |
| CN105198802A (zh) * | 2015-11-03 | 2015-12-30 | 江苏梦得电镀化学品有限公司 | 一种2-甲基-3-溴吡啶的制备方法 |
| CA3008279A1 (en) | 2015-12-14 | 2017-06-22 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
| EP3389634B1 (en) | 2015-12-14 | 2021-10-06 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
| JP7055380B2 (ja) | 2015-12-22 | 2022-04-18 | エックス4 ファーマシューティカルズ, インコーポレイテッド | 免疫不全疾患を処置するための方法 |
| CA3019394A1 (en) | 2016-04-08 | 2017-10-12 | X4 Pharmaceuticals, Inc. | Methods for treating cancer |
| JP6994767B2 (ja) | 2016-06-21 | 2022-01-14 | エックス4 ファーマシューティカルズ, インコーポレイテッド | Cxcr4阻害剤およびその使用 |
| CN109640988A (zh) | 2016-06-21 | 2019-04-16 | X4 制药有限公司 | Cxcr4抑制剂及其用途 |
| CA3027498A1 (en) | 2016-06-21 | 2017-12-28 | X4 Pharmaceuticals, Inc. | Cxcr4 inhibitors and uses thereof |
| WO2018073248A1 (en) | 2016-10-17 | 2018-04-26 | Icm (Institut Du Cerveau Et De La Moelle Épinière) | Prognosis of demyelinating diseases patients and treatment thereof |
| EP3820480A4 (en) | 2018-07-11 | 2022-03-09 | Arrys Therapeutics, Inc. | POLYMORPHIC COMPOUNDS AND USES THEREOF |
| US10548889B1 (en) | 2018-08-31 | 2020-02-04 | X4 Pharmaceuticals, Inc. | Compositions of CXCR4 inhibitors and methods of preparation and use |
| GB201910608D0 (en) | 2019-07-24 | 2019-09-04 | Enterprise Therapeutics Ltd | Compounds |
| CN115515585A (zh) | 2020-03-10 | 2022-12-23 | X4 制药有限公司 | 用于治疗中性粒细胞减少症的方法 |
| WO2021215544A1 (en) * | 2020-04-24 | 2021-10-28 | Taiho Pharmaceutical Co., Ltd. | Kras g12d protein inhibitors |
| CN112110853A (zh) * | 2020-09-23 | 2020-12-22 | 海南梵圣生物科技有限公司 | 一种合成3-羟基-2-吡啶甲酸及其衍生物的方法 |
| CN116375650B (zh) * | 2022-12-30 | 2025-08-05 | 浙江美诺华药物化学有限公司 | 一种替戈拉生中间体的制备方法 |
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| US6750348B1 (en) * | 1999-03-24 | 2004-06-15 | Anormed, Inc. | Chemokine receptor binding heterocyclic compounds |
| WO2000056729A1 (en) * | 1999-03-24 | 2000-09-28 | Anormed Inc. | Chemokine recpetor binding heterocyclic compounds |
| HUP0301094A2 (hu) * | 2000-09-15 | 2003-09-29 | Anormed Inc. | Kemonikinreceptorhoz kötżdż heterociklusos vegyületek, e vegyületeket tartalmazó gyógyászati készítmények és alkalmazásuk |
| CA2419224A1 (en) * | 2000-09-15 | 2002-03-21 | Anormed Inc. | Chemokine receptor binding heterocyclic compounds |
-
2001
- 2001-09-17 CA CA002419224A patent/CA2419224A1/en not_active Abandoned
- 2001-09-17 KR KR10-2003-7003710A patent/KR20030029998A/ko not_active Abandoned
- 2001-09-17 IL IL15422701A patent/IL154227A0/xx unknown
- 2001-09-17 EP EP01971574A patent/EP1317445B1/en not_active Expired - Lifetime
- 2001-09-17 AU AU2001291569A patent/AU2001291569B2/en not_active Ceased
- 2001-09-17 TR TR2003/00322T patent/TR200300322T2/xx unknown
- 2001-09-17 HU HU0301093A patent/HUP0301093A2/hu unknown
- 2001-09-17 MX MXPA03002326A patent/MXPA03002326A/es active IP Right Grant
- 2001-09-17 PL PL36093201A patent/PL360932A1/xx unknown
- 2001-09-17 CN CN01815627A patent/CN1457339A/zh active Pending
- 2001-09-17 SG SG200502184A patent/SG126007A1/en unknown
- 2001-09-17 RU RU2003110577/04A patent/RU2289581C2/ru not_active IP Right Cessation
- 2001-09-17 AU AU9156901A patent/AU9156901A/xx active Pending
- 2001-09-17 HK HK03104377.2A patent/HK1052011A1/zh unknown
- 2001-09-17 BR BR0113930-4A patent/BR0113930A/pt not_active IP Right Cessation
- 2001-09-17 DE DE60137944T patent/DE60137944D1/de not_active Expired - Lifetime
- 2001-09-17 JP JP2002526853A patent/JP2004508422A/ja active Pending
- 2001-09-17 ES ES01971574T patent/ES2325909T3/es not_active Expired - Lifetime
- 2001-09-17 NZ NZ524420A patent/NZ524420A/en unknown
- 2001-09-17 WO PCT/CA2001/001326 patent/WO2002022600A2/en not_active Ceased
- 2001-09-17 AT AT01971574T patent/ATE425157T1/de not_active IP Right Cessation
- 2001-09-17 US US09/957,682 patent/US6864265B2/en not_active Expired - Fee Related
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2003
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- 2004-06-01 US US10/858,910 patent/US7084155B2/en not_active Expired - Fee Related
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Also Published As
| Publication number | Publication date |
|---|---|
| AU2001291569B2 (en) | 2007-07-26 |
| KR20030029998A (ko) | 2003-04-16 |
| US20060128750A1 (en) | 2006-06-15 |
| US6864265B2 (en) | 2005-03-08 |
| US7396840B2 (en) | 2008-07-08 |
| JP2004508422A (ja) | 2004-03-18 |
| SG126007A1 (en) | 2006-10-30 |
| HUP0301093A2 (hu) | 2003-09-29 |
| NZ524420A (en) | 2005-04-29 |
| WO2002022600A2 (en) | 2002-03-21 |
| US20030018046A1 (en) | 2003-01-23 |
| PL360932A1 (en) | 2004-09-20 |
| DE60137944D1 (de) | 2009-04-23 |
| ES2325909T3 (es) | 2009-09-24 |
| IL154227A0 (en) | 2003-07-31 |
| RU2289581C2 (ru) | 2006-12-20 |
| CA2419224A1 (en) | 2002-03-21 |
| NO20031179D0 (no) | 2003-03-14 |
| BR0113930A (pt) | 2003-06-24 |
| MXPA03002326A (es) | 2003-06-06 |
| ATE425157T1 (de) | 2009-03-15 |
| WO2002022600A3 (en) | 2002-05-10 |
| CN1457339A (zh) | 2003-11-19 |
| HK1052011A1 (zh) | 2003-08-29 |
| TR200300322T2 (tr) | 2003-09-22 |
| US7084155B2 (en) | 2006-08-01 |
| EP1317445A2 (en) | 2003-06-11 |
| EP1317445B1 (en) | 2009-03-11 |
| AU9156901A (en) | 2002-03-26 |
| US20040220207A1 (en) | 2004-11-04 |
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