NO20031739L - Fremgangsmåte for rensing av pravastatin - Google Patents

Fremgangsmåte for rensing av pravastatin

Info

Publication number
NO20031739L
NO20031739L NO20031739A NO20031739A NO20031739L NO 20031739 L NO20031739 L NO 20031739L NO 20031739 A NO20031739 A NO 20031739A NO 20031739 A NO20031739 A NO 20031739A NO 20031739 L NO20031739 L NO 20031739L
Authority
NO
Norway
Prior art keywords
pravastatin
purification
procedure
Prior art date
Application number
NO20031739A
Other languages
English (en)
Other versions
NO20031739D0 (no
Inventor
Nobunari Sugio
Shunshi Kojima
Yasuyuki Takamatsu
Minoru Hagisawa
Kiyoshi Hamano
Mutsuo Suzuki
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=18794392&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20031739(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of NO20031739D0 publication Critical patent/NO20031739D0/no
Publication of NO20031739L publication Critical patent/NO20031739L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/48—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/48—Separation; Purification; Stabilisation; Use of additives
    • C07C67/58—Separation; Purification; Stabilisation; Use of additives by liquid-liquid treatment
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/48—Separation; Purification; Stabilisation; Use of additives
    • C07C67/60—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
    • C07C69/22—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety
    • C07C69/33—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety esterified with hydroxy compounds having more than three hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/26—All rings being cycloaliphatic the ring system containing ten carbon atoms
    • C07C2602/28—Hydrogenated naphthalenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO20031739A 2000-10-16 2003-04-15 Fremgangsmåte for rensing av pravastatin NO20031739L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000315256A JP3236282B1 (ja) 2000-10-16 2000-10-16 プラバスタチンを精製する方法
PCT/JP2001/009045 WO2002032848A1 (en) 2000-10-16 2001-10-15 Method of purifying plavastatin

Publications (2)

Publication Number Publication Date
NO20031739D0 NO20031739D0 (no) 2003-04-15
NO20031739L true NO20031739L (no) 2003-06-13

Family

ID=18794392

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20031739A NO20031739L (no) 2000-10-16 2003-04-15 Fremgangsmåte for rensing av pravastatin

Country Status (19)

Country Link
US (1) US20030216596A1 (no)
EP (4) EP1327626A4 (no)
JP (1) JP3236282B1 (no)
KR (1) KR20030042018A (no)
CN (4) CN1868996A (no)
AU (1) AU2001294258A1 (no)
BR (1) BR0114681A (no)
CA (1) CA2425883A1 (no)
CZ (1) CZ20031052A3 (no)
HU (1) HUP0303106A3 (no)
IL (1) IL155360A0 (no)
MX (1) MXPA03003347A (no)
NO (1) NO20031739L (no)
NZ (3) NZ536891A (no)
PL (1) PL360934A1 (no)
RU (2) RU2260582C2 (no)
SK (1) SK4532003A3 (no)
WO (1) WO2002032848A1 (no)
ZA (1) ZA200302966B (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3422791B2 (ja) 2002-08-06 2003-06-30 三共株式会社 プラバスタチンの単離・精製方法
TW589178B (en) * 2003-02-21 2004-06-01 China Chemical & Pharmaceutica A novel industrial process to obtain pravastatin sodium of high purity
EP1452519A1 (en) * 2003-02-25 2004-09-01 Balkanpharma-Razgrad AD Method for the isolation and purification of pravastatin sodium
US20090042979A1 (en) * 2004-08-06 2009-02-12 Transform Pharmaceuticals Inc. Novel Statin Pharmaceutical Compositions and Related Methods of Treatment
WO2006017692A2 (en) * 2004-08-06 2006-02-16 Transform Pharmaceuticals, Inc. Novel fenofibrate formulations and related methods of treatment
KR20070038553A (ko) * 2004-08-06 2007-04-10 트렌스폼 파마수티컬스 인코퍼레이티드 신규한 스타틴 약제학적 조성물 및 관련된 치료방법
CN100361954C (zh) * 2005-05-16 2008-01-16 天津市冠东科技有限公司 制备普伐他汀结晶体的干燥方法
JP4813841B2 (ja) * 2005-07-25 2011-11-09 キユーピー株式会社 プラバスタチンナトリウムの製造方法
JP2012507299A (ja) * 2008-10-31 2012-03-29 バイオジェン・アイデック・エムエイ・インコーポレイテッド Ｌｉｇｈｔ標的分子およびその使用
CN109796333B (zh) * 2019-01-25 2021-04-09 北大方正集团有限公司 一种从发酵液中提取纯化普伐他汀钠的方法
CN112778120B (zh) * 2019-11-08 2024-05-17 上海现代制药股份有限公司 一种降血脂类药物氧化杂质的制备方法
CN119915919A (zh) * 2023-10-31 2025-05-02 上海现代制药股份有限公司 普伐他汀有关物质的检测方法
CN119915920A (zh) * 2023-10-31 2025-05-02 上海现代制药股份有限公司 普伐他汀有关物质的检测方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX7065E (es) * 1980-06-06 1987-04-10 Sankyo Co Un procedimiento microbiologico para preparar derivados de ml-236b
JPS5889191A (ja) * 1981-11-20 1983-05-27 Sankyo Co Ltd ３−ヒドロキシ−ｍｌ−２３６ｂ誘導体の製造法
US5202029A (en) 1991-03-13 1993-04-13 Caron Kabushiki Kaisha Process for purification of hmg-coa reductase inhibitors
NZ250609A (en) * 1992-12-28 1995-07-26 Sankyo Co Hexahydronaphthalene esters and ring closed lactones; preparation and medicaments
IL108432A (en) * 1993-01-29 1997-09-30 Sankyo Co DERIVATIVES OF 3, 5-DIHYDROXY-7- £1, 2, 6, 7, 8, 8a-HEXAHYDRO-2- METHYL-8- (SUBSTITUTED ALKANOYLOXY)-1-NAPHTHYL| HEPTANOIC ACID AND THEIR LACTONES, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
WO1997006128A1 (en) * 1995-08-03 1997-02-20 Gist-Brocades B.V. Selective process for the deacylation of acylated compounds
SI9800046A (sl) 1998-02-18 1999-08-31 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Postopek za pridobivanje inhibitorjev HMG-CoA reduktaze visoke čistosti
SI20305A (sl) * 1999-08-06 2001-02-28 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Kristali natrijeve soli pravastatina
SI20072A (sl) 1998-09-18 2000-04-30 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Postopek za pridobivanje inhibitorjev HMG-CoA reduktaze
JP2000279174A (ja) 1999-03-30 2000-10-10 Bml Inc ヒトｌｄｌレセプターに対するモノクローナル抗体及びこれを用いる家族性高脂血症の判定方法
HUP9902352A1 (hu) * 1999-07-12 2000-09-28 Gyógyszerkutató Intézet Kft. Eljárás pravasztatin mikrobiológiai előállítására
HRP20030347A2 (en) * 2000-10-05 2005-04-30 Teva Gy�gyszergy�r R�szv�nyt�rsas�g Pravastatin sodium substantially free of pravastatin lactone and epi-pravastatin, and compositions containing same

Also Published As

Publication number Publication date
CN1481353A (zh) 2004-03-10
EP1327626A1 (en) 2003-07-16
WO2002032848A1 (en) 2002-04-25
BR0114681A (pt) 2003-12-09
CZ20031052A3 (cs) 2003-09-17
EP1514862A1 (en) 2005-03-16
NZ536891A (en) 2005-05-27
US20030216596A1 (en) 2003-11-20
CN1679535A (zh) 2005-10-12
PL360934A1 (en) 2004-09-20
NZ536892A (en) 2005-05-27
KR20030042018A (ko) 2003-05-27
HUP0303106A2 (hu) 2003-12-29
AU2001294258A1 (en) 2002-04-29
MXPA03003347A (es) 2003-06-19
NO20031739D0 (no) 2003-04-15
HUP0303106A3 (en) 2004-10-28
CA2425883A1 (en) 2003-04-15
JP2002121174A (ja) 2002-04-23
EP1327626A4 (en) 2004-08-18
CN1868996A (zh) 2006-11-29
IL155360A0 (en) 2003-11-23
CN1690037A (zh) 2005-11-02
EP1514863A1 (en) 2005-03-16
SK4532003A3 (en) 2003-10-07
NZ525256A (en) 2005-01-28
RU2260582C2 (ru) 2005-09-20
EP1522589A1 (en) 2005-04-13
ZA200302966B (en) 2004-07-15
RU2005113661A (ru) 2006-11-10
JP3236282B1 (ja) 2001-12-10

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