NO20032754D0 - Urea- og/eller uretanderivater som integrininhibitorer - Google Patents

Urea- og/eller uretanderivater som integrininhibitorer

Info

Publication number: NO20032754D0
Authority: NO; Norway
Prior art keywords: urea; integrin inhibitors; urethane derivatives; urethane; derivatives
Prior art date: 2000-12-18

Application number

NO20032754A

Other languages

English (en)

Norwegian (no)

Other versions

NO20032754L (no

Inventor

Wolfgang Staehle

Alfred Jonczyk

Oliver Schadt

Simon Goodman

Original Assignee

Merck Patent Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-12-18

Filing date

2003-06-17

Publication date

2003-06-17

2003-06-17 Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh

2003-06-17 Publication of NO20032754L publication Critical patent/NO20032754L/no

2003-06-17 Publication of NO20032754D0 publication Critical patent/NO20032754D0/no

Links

XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 title abstract 2
239000004202 carbamide Substances 0.000 title abstract 2
239000003112 inhibitor Substances 0.000 title abstract 2
102000006495 integrins Human genes 0.000 title abstract 2
108010044426 integrins Proteins 0.000 title abstract 2
150000003673 urethanes Chemical class 0.000 title abstract 2
206010003210 Arteriosclerosis Diseases 0.000 abstract 1
206010061216 Infarction Diseases 0.000 abstract 1
206010061218 Inflammation Diseases 0.000 abstract 1
206010028980 Neoplasm Diseases 0.000 abstract 1
208000001132 Osteoporosis Diseases 0.000 abstract 1
208000037273 Pathologic Processes Diseases 0.000 abstract 1
208000007536 Thrombosis Diseases 0.000 abstract 1
238000002399 angioplasty Methods 0.000 abstract 1
208000011775 arteriosclerosis disease Diseases 0.000 abstract 1
230000000747 cardiac effect Effects 0.000 abstract 1
208000029078 coronary artery disease Diseases 0.000 abstract 1
230000007574 infarction Effects 0.000 abstract 1
208000015181 infectious disease Diseases 0.000 abstract 1
230000004054 inflammatory process Effects 0.000 abstract 1
230000009054 pathological process Effects 0.000 abstract 1
230000000644 propagated effect Effects 0.000 abstract 1
208000037803 restenosis Diseases 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
239000012453 solvate Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Oncology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Rheumatology (AREA)
Physical Education & Sports Medicine (AREA)
Communicable Diseases (AREA)
Orthopedic Medicine & Surgery (AREA)
Ophthalmology & Optometry (AREA)
Vascular Medicine (AREA)
Neurology (AREA)
Dermatology (AREA)
Hospice & Palliative Care (AREA)
Neurosurgery (AREA)
Urology & Nephrology (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Virology (AREA)
Hematology (AREA)
Diabetes (AREA)
Surgery (AREA)
Immunology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

NO20032754A 2000-12-18 2003-06-17 Urea- og/eller uretanderivater som integrininhibitorer NO20032754D0 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10063173A DE10063173A1 (de)	2000-12-18	2000-12-18	Harnstoff- und Urethanderivate
PCT/EP2001/014039 WO2002050039A1 (en)	2000-12-18	2001-11-30	Urea and urethane derivatives as integrin inhibitors

Publications (2)

Publication Number	Publication Date
NO20032754L NO20032754L (no)	2003-06-17
NO20032754D0 true NO20032754D0 (no)	2003-06-17

Family

ID=7667710

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20032754A NO20032754D0 (no)	2000-12-18	2003-06-17	Urea- og/eller uretanderivater som integrininhibitorer

Country Status (23)

Country	Link
US (1)	US7135587B2 (de)
EP (1)	EP1343764B1 (de)
JP (1)	JP4216071B2 (de)
KR (1)	KR20030063432A (de)
CN (1)	CN1481364A (de)
AR (1)	AR035608A1 (de)
AT (1)	ATE274497T1 (de)
AU (1)	AU2002217078A1 (de)
BR (1)	BR0116202A (de)
CA (1)	CA2431974C (de)
CZ (1)	CZ20031775A3 (de)
DE (2)	DE10063173A1 (de)
DK (1)	DK1343764T3 (de)
ES (1)	ES2227063T3 (de)
HU (1)	HUP0302753A3 (de)
MX (1)	MXPA03005431A (de)
NO (1)	NO20032754D0 (de)
PL (1)	PL361745A1 (de)
PT (1)	PT1343764E (de)
RU (1)	RU2003121015A (de)
SK (1)	SK8182003A3 (de)
WO (1)	WO2002050039A1 (de)
ZA (1)	ZA200305550B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE10204789A1 (de)	2002-02-06	2003-08-14	Merck Patent Gmbh	Inhibitoren des Integrins alpha¶v¶beta6
NZ535425A (en)	2002-03-13	2008-05-30	Biogen Idec Inc	Anti-alphavbeta6 antibodies
ATE399542T1 (de) *	2003-10-01	2008-07-15	Merck Patent Gmbh	Alfavbeta3 und alfavbeta6 integrin antagonisten als antifibrotische mittel
CN104072614B (zh)	2005-07-08	2017-04-26	生物基因Ma公司	抗-αvβ6 抗体及其用途
CN101563105B (zh)	2006-07-10	2013-01-23	拜奥根Idec马萨诸塞公司	用于抑制smad4-缺陷癌症的组合物和方法
JP2010506944A (ja) *	2006-10-19	2010-03-04	ザリージェンツオブザユニバーシティオブカリフォルニア	インテグリンαＶβ６のアンタゴニストを用いる慢性喘息の処置および予防
AT509266B1 (de) *	2009-12-28	2014-07-15	Univ Wien Tech	Substituierte pyridine und pyrimidine
CN102353728B (zh) *	2011-06-29	2013-03-27	中国食品发酵工业研究院	一种黄酒生产过程质量控制快速检测方法
WO2014143739A2 (en)	2013-03-15	2014-09-18	Biogen Idec Ma Inc.	Anti-alpha v beta 6 antibodies and uses thereof
WO2014144466A1 (en)	2013-03-15	2014-09-18	Biogen Idec Ma Inc.	Anti-alpha v beta 6 antibodies and uses thereof
UA123219C2 (uk)	2015-10-23	2021-03-03	Віфор (Інтернаціональ) Аґ	Інгібітори феропортину
JOP20180036A1 (ar)	2017-04-18	2019-01-30	Vifor Int Ag	أملاح لمثبطات فروبورتين جديدة

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6306840B1 (en)	1995-01-23	2001-10-23	Biogen, Inc.	Cell adhesion inhibitors
PL343770A1 (en)	1998-04-16	2001-09-10	Texas Biotechnology Corp	N,n-disubstituted amides that inhibit the binding of integrins to their receptors
GB9909409D0 (en) *	1999-04-24	1999-06-23	Zeneca Ltd	Chemical compounds
DE19939980A1 (de) *	1999-08-24	2001-03-01	Merck Patent Gmbh	Inhibitoren des Integrins alphavbeta¶3¶

2000
- 2000-12-18 DE DE10063173A patent/DE10063173A1/de not_active Withdrawn
2001
- 2001-11-30 WO PCT/EP2001/014039 patent/WO2002050039A1/en not_active Ceased
- 2001-11-30 CN CNA01820791XA patent/CN1481364A/zh active Pending
- 2001-11-30 DK DK01271360T patent/DK1343764T3/da active
- 2001-11-30 HU HU0302753A patent/HUP0302753A3/hu unknown
- 2001-11-30 PL PL01361745A patent/PL361745A1/xx unknown
- 2001-11-30 MX MXPA03005431A patent/MXPA03005431A/es unknown
- 2001-11-30 CA CA2431974A patent/CA2431974C/en not_active Expired - Fee Related
- 2001-11-30 JP JP2002551536A patent/JP4216071B2/ja not_active Expired - Fee Related
- 2001-11-30 RU RU2003121015/04A patent/RU2003121015A/ru not_active Application Discontinuation
- 2001-11-30 DE DE60105192T patent/DE60105192T2/de not_active Expired - Lifetime
- 2001-11-30 ES ES01271360T patent/ES2227063T3/es not_active Expired - Lifetime
- 2001-11-30 CZ CZ20031775A patent/CZ20031775A3/cs unknown
- 2001-11-30 AT AT01271360T patent/ATE274497T1/de not_active IP Right Cessation
- 2001-11-30 SK SK818-2003A patent/SK8182003A3/sk unknown
- 2001-11-30 AU AU2002217078A patent/AU2002217078A1/en not_active Abandoned
- 2001-11-30 PT PT01271360T patent/PT1343764E/pt unknown
- 2001-11-30 BR BR0116202-0A patent/BR0116202A/pt not_active Application Discontinuation
- 2001-11-30 EP EP01271360A patent/EP1343764B1/de not_active Expired - Lifetime
- 2001-11-30 KR KR10-2003-7008122A patent/KR20030063432A/ko not_active Withdrawn
- 2001-11-30 US US10/450,855 patent/US7135587B2/en not_active Expired - Fee Related
- 2001-12-14 AR ARP010105796A patent/AR035608A1/es unknown
2003
- 2003-06-17 NO NO20032754A patent/NO20032754D0/no unknown
- 2003-07-17 ZA ZA200305550A patent/ZA200305550B/en unknown

Also Published As

Publication number	Publication date
PT1343764E (pt)	2005-01-31
ATE274497T1 (de)	2004-09-15
EP1343764B1 (de)	2004-08-25
DE10063173A1 (de)	2002-06-20
ES2227063T3 (es)	2005-04-01
RU2003121015A (ru)	2005-02-10
AR035608A1 (es)	2004-06-16
NO20032754L (no)	2003-06-17
CA2431974C (en)	2010-08-17
US7135587B2 (en)	2006-11-14
CN1481364A (zh)	2004-03-10
WO2002050039A1 (en)	2002-06-27
US20040063644A1 (en)	2004-04-01
PL361745A1 (en)	2004-10-04
EP1343764A1 (de)	2003-09-17
HUP0302753A3 (en)	2005-03-29
HUP0302753A2 (hu)	2003-12-29
DE60105192T2 (de)	2005-09-08
JP2004516282A (ja)	2004-06-03
DE60105192D1 (de)	2004-09-30
BR0116202A (pt)	2003-12-23
DK1343764T3 (da)	2004-12-06
ZA200305550B (en)	2004-10-18
MXPA03005431A (es)	2003-09-10
JP4216071B2 (ja)	2009-01-28
CA2431974A1 (en)	2002-06-27
SK8182003A3 (en)	2003-10-07
AU2002217078A1 (en)	2002-07-01
CZ20031775A3 (cs)	2003-09-17
KR20030063432A (ko)	2003-07-28

Publication	Publication Date	Title
NO20010203L (no)	2001-01-12	Diacylhydrazinderivater som integrininhibitorer
WO2001058893A3 (de)	2002-04-18	Indol-3-yl-derivate und deren verwendung als integrin-inhibitoren
TW372232B (en)	1999-10-21	Phenylalanine derivatives
NO20032754D0 (no)	2003-06-17	Urea- og/eller uretanderivater som integrininhibitorer
NZ511927A (en)	2004-02-27	Phenylglycine derivatives
DK1259485T3 (da)	2006-04-10	Benzamider og beslægtede inhibitorer for faktor Xa
NO20060971L (no)	2006-05-02	Pyridazinderivater og deres anvendelse som terapeutiske midler
UY26899A1 (es)	2002-03-22	Derivados de pirazol fusionados
TR200201505T2 (tr)	2003-01-21	Terapötik maddeler olarak pirazolopirimidinler
BR9710737A (pt)	2000-01-11	Pentafluorobenzenosulfonamidas e análogos.
CY1108041T1 (el)	2013-09-04	Αναστολεις της rho-κινασης
DE60121461D1 (de)	2006-08-24	Kondensierte pyridoindolderivate
MXPA03008215A (es)	2004-01-29	Inhibidores de integrina alfa v beta 6.
BR0008310A (pt)	2002-01-22	Derivados de alfa-alanina
MY133897A (en)	2007-11-30	N-(4-carb-amimidophenyl) glycineamide derivatives
CA2280727A1 (en)	1998-08-20	Bicyclic amino acids
TR200201168T2 (tr)	2002-08-21	CGRP-Antagonistleri-yeni siklopropanlar içeren ilaçlar ve üretim yöntemleri.
SE0101932D0 (sv)	2001-05-31	Pharmaceutical combinations
NO20044526L (no)	2004-12-21	Hemisterlinderivater og anvendelser derav
DK1077218T3 (da)	2007-09-24	Peptidomimetiske forbindelser omfattende RGD-sekvenser, som er nyttige som integrininhibitorer
CA2348391A1 (en)	2000-05-11	Chromenone and chromanone derivatives as integrin inhibitors
BR0308195A (pt)	2005-01-04	Derivados de isoquinolina
BR0113374A (pt)	2003-07-08	Derivados de bifenila e seu uso como inibidores da integrina
BR0012391A (pt)	2002-03-19	Derivados de diacilidrazina
BR9813719A (pt)	2000-10-17	Agentes terapêuticos