NO20034497L - Somatostatin agonister - Google Patents

Somatostatin agonister

Info

Publication number: NO20034497L
Authority: NO; Norway
Prior art keywords: somatostatin agonists; somatostatin; agonists
Prior art date: 2001-04-09

Application number

NO20034497A

Other languages

English (en)

Other versions

NO20034497D0 (no

Inventor

David H Coy

Walajapet G Rajeswaran

Original Assignee

Univ Tulane

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-04-09

Filing date

2003-10-08

Publication date

2003-10-27

2003-10-08 Application filed by Univ Tulane filed Critical Univ Tulane

2003-10-08 Publication of NO20034497D0 publication Critical patent/NO20034497D0/no

2003-10-27 Publication of NO20034497L publication Critical patent/NO20034497L/no

Links

102000005157 Somatostatin Human genes 0.000 title 1
108010056088 Somatostatin Proteins 0.000 title 1
239000000556 agonist Substances 0.000 title 1
NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 title 1
229960000553 somatostatin Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C07K14/6555—Somatostatins at least 1 amino acid in D-form
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
- A—HUMAN NECESSITIES
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- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
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- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
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- A61P31/14—Antivirals for RNA viruses
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A61P5/08—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Hematology (AREA)
Molecular Biology (AREA)
Reproductive Health (AREA)
Biophysics (AREA)
Cardiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Obesity (AREA)
Biochemistry (AREA)
Heart & Thoracic Surgery (AREA)
Oncology (AREA)
Physical Education & Sports Medicine (AREA)
Psychiatry (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Toxicology (AREA)
Virology (AREA)
AIDS & HIV (AREA)
Orthopedic Medicine & Surgery (AREA)
Nutrition Science (AREA)

NO20034497A 2001-04-09 2003-10-08 Somatostatin agonister NO20034497L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US28252601P	2001-04-09	2001-04-09
PCT/US2002/010882 WO2002081499A2 (en)	2001-04-09	2002-04-08	Somatostatin agonists

Publications (2)

Publication Number	Publication Date
NO20034497D0 NO20034497D0 (no)	2003-10-08
NO20034497L true NO20034497L (no)	2003-10-27

Family

ID=23081905

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20034497A NO20034497L (no)	2001-04-09	2003-10-08	Somatostatin agonister

Country Status (15)

Country	Link
US (2)	US7312304B2 (no)
EP (1)	EP1397150A4 (no)
JP (2)	JP2004531520A (no)
KR (1)	KR20030088494A (no)
CN (1)	CN1541102A (no)
AU (1)	AU2002256105B2 (no)
CA (1)	CA2443085A1 (no)
CZ (1)	CZ20032707A3 (no)
HU (1)	HUP0303727A2 (no)
IL (1)	IL158051A0 (no)
MX (1)	MXPA03009048A (no)
NO (1)	NO20034497L (no)
PL (1)	PL368941A1 (no)
RU (1)	RU2259375C2 (no)
WO (1)	WO2002081499A2 (no)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU3290302A (en) *	2000-10-20	2002-04-29	Univ Tulane	Urotensin-ii agonists and antagonists
RU2263678C2 (ru)	2001-03-08	2005-11-10	Дзе Администрейторс Оф Дзе Тьюлейн Эдьюкейшнл Фанд	Антагонисты соматостатина
AU2004293815B2 (en)	2003-11-20	2010-07-22	The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc.	Portable hand pump for evacuation of fluids
US8337475B2 (en)	2004-10-12	2012-12-25	C. R. Bard, Inc.	Corporeal drainage system
BRPI0609355A2 (pt) *	2005-04-13	2010-03-30	Univ Erasmus Medical Ct	uso de um antagonista do hormÈnio de crescimento, e de uma somatostatina ou de um agonista da somatostatina, na preparação de uma composição para atenuar os efeitos do hormÈnio de crescimento
US8177772B2 (en)	2005-09-26	2012-05-15	C. R. Bard, Inc.	Catheter connection systems
PL2118123T3 (pl)	2007-01-31	2016-06-30	Dana Farber Cancer Inst Inc	Stabilizowane peptydy p53 i ich zastosowania
JP5631201B2 (ja)	2007-03-28	2014-11-26	プレジデントアンドフェローズオブハーバードカレッジ	ステッチングされたポリペプチド
KR102104762B1 (ko)	2010-08-13	2020-04-24	에일러론 테라퓨틱스 인코포레이티드	펩티도미메틱 거대고리
EP2768518A4 (en)	2011-10-18	2015-05-27	Aileron Therapeutics Inc	PEPTIDOMIMETIC MACROCYCLES
RU2642299C2 (ru)	2012-02-15	2018-01-24	Эйлерон Терапьютикс, Инк.	P53 пептидомиметические макроциклы
CA2864120A1 (en)	2012-02-15	2013-08-22	Aileron Therapeutics, Inc.	Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles
WO2013132505A1 (en)	2012-03-09	2013-09-12	Natco Pharma Limited	Improved process for preparation of octreotide by solution phase peptide synthesis
AU2013246908B2 (en) *	2012-04-12	2016-06-30	Novartis Ag	Combination of somatostatin-analogs with 11beta-hydroxylase inhibitors
BR112015009470A2 (pt)	2012-11-01	2019-12-17	Aileron Therapeutics Inc	aminoácidos dissubstituídos e seus métodos de preparação e uso
EP3007704B1 (en) *	2013-06-13	2021-01-06	Antisense Therapeutics Ltd	Combination therapy for acromegaly
EP3197478A4 (en)	2014-09-24	2018-05-30	Aileron Therapeutics, Inc.	Peptidomimetic macrocycles and uses thereof
JP2018516844A (ja)	2015-03-20	2018-06-28	エルロン・セラピューティクス・インコーポレイテッドＡｉｌｅｒｏｎＴｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ．	ペプチド模倣大環状分子およびその使用
WO2025137443A1 (en) *	2023-12-22	2025-06-26	Rayzebio, Inc.	Radiopharmaceutical compositions targeting somatostatin receptors and uses thereof
AR134788A1 (es) *	2023-12-22	2026-04-01	Rayzebio Inc	Radiofármacos dirigidos al receptor 2 de somatostatina y sus usos

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH679045A5 (no) *	1987-06-29	1991-12-13	Sandoz Ag
US5633263A (en) *	1989-04-26	1997-05-27	The Administrators Of The Tulane Educational Fund	Linear somatostatin analogs
JP2882679B2 (ja) *	1989-04-26	1999-04-12	ジ・アドミニストレーターズ・オブ・ザ・ツーレイン・エデュケイショナル・ファンド	線状ソマトスタチン類似体
ES2091907T3 (es) *	1989-12-08	1996-11-16	Univ Tulane	Analogos octapeptidos de somatostina con una threonina en la sexta posicion.
US5462926A (en) *	1992-07-27	1995-10-31	Biomeasure, Inc.	Neuromedin B receptor antagonists which demonstrate selectivity
US5504069A (en) *	1993-02-11	1996-04-02	Biomeasure, Inc.	Inhibition of trauma-induced tumor growth
US5583104A (en) *	1993-12-06	1996-12-10	Mayo Foundation For Medical Research And Education	Treatment of proliferation of bile duct epithelium
GB9402767D0 (en) *	1994-02-14	1994-04-06	Sandoz Ltd	Improvements in or relating to organic compounds
US6051206A (en) *	1994-06-03	2000-04-18	Diatide, Inc	Radiolabeled somatostatin-derived peptides for imaging and therapeutic uses
RU2177006C2 (ru) *	1995-09-29	2001-12-20	Биомежер Инкорпорэйтед	Циклические пептидные аналоги соматостатина
US6355613B1 (en) *	1996-07-31	2002-03-12	Peptor Limited	Conformationally constrained backbone cyclized somatostatin analogs
AU3215597A (en) *	1996-08-30	1998-03-19	Biomeasure Incorporated	Method of inhibiting fibrosis with a somatostatin agonist
IL130166A0 (en) *	1996-12-04	2000-06-01	Sod Conseils Rech Applic	Somatostatin antagonists
US6262229B1 (en) *	1996-12-04	2001-07-17	Biomeasure Incorporated	Somatostatin antagonists
US6025372A (en) *	1997-04-04	2000-02-15	Merck & Co., Inc.	Somatostatin agonists
US6004928A (en) *	1997-05-13	1999-12-21	Biomeasure, Incorporated	Method of treating hyperlipidemia
RU2263678C2 (ru) *	2001-03-08	2005-11-10	Дзе Администрейторс Оф Дзе Тьюлейн Эдьюкейшнл Фанд	Антагонисты соматостатина

2002
- 2002-04-08 JP JP2002579485A patent/JP2004531520A/ja active Pending
- 2002-04-08 RU RU2003132548/04A patent/RU2259375C2/ru not_active IP Right Cessation
- 2002-04-08 KR KR10-2003-7013240A patent/KR20030088494A/ko not_active Ceased
- 2002-04-08 CZ CZ20032707A patent/CZ20032707A3/cs unknown
- 2002-04-08 CA CA002443085A patent/CA2443085A1/en not_active Abandoned
- 2002-04-08 US US10/474,248 patent/US7312304B2/en not_active Expired - Lifetime
- 2002-04-08 PL PL02368941A patent/PL368941A1/xx not_active Application Discontinuation
- 2002-04-08 IL IL15805102A patent/IL158051A0/xx unknown
- 2002-04-08 MX MXPA03009048A patent/MXPA03009048A/es unknown
- 2002-04-08 EP EP02725548A patent/EP1397150A4/en not_active Withdrawn
- 2002-04-08 WO PCT/US2002/010882 patent/WO2002081499A2/en not_active Ceased
- 2002-04-08 CN CNA02808005XA patent/CN1541102A/zh active Pending
- 2002-04-08 HU HU0303727A patent/HUP0303727A2/hu unknown
- 2002-04-08 AU AU2002256105A patent/AU2002256105B2/en not_active Expired - Fee Related
2003
- 2003-10-08 NO NO20034497A patent/NO20034497L/no not_active Application Discontinuation
2007
- 2007-09-21 JP JP2007245290A patent/JP2008069160A/ja active Pending
- 2007-10-11 US US11/973,954 patent/US20080090756A1/en not_active Abandoned

Also Published As

Publication number	Publication date
JP2008069160A (ja)	2008-03-27
KR20030088494A (ko)	2003-11-19
CN1541102A (zh)	2004-10-27
US7312304B2 (en)	2007-12-25
PL368941A1 (en)	2005-04-04
US20040171530A1 (en)	2004-09-02
NO20034497D0 (no)	2003-10-08
HUP0303727A2 (hu)	2004-03-01
IL158051A0 (en)	2004-03-28
AU2002256105B2 (en)	2006-04-06
RU2003132548A (ru)	2005-02-27
CA2443085A1 (en)	2002-10-17
MXPA03009048A (es)	2004-02-12
WO2002081499A3 (en)	2003-05-08
EP1397150A4 (en)	2005-01-26
EP1397150A2 (en)	2004-03-17
RU2259375C2 (ru)	2005-08-27
JP2004531520A (ja)	2004-10-14
CZ20032707A3 (cs)	2004-01-14
US20080090756A1 (en)	2008-04-17
WO2002081499A2 (en)	2002-10-17

Legal Events

Date	Code	Title	Description
2006-11-27	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
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