NO20041295L - Tieno(1,3)oksazin-4-oner med lipaseinhiberende aktivitet - Google Patents

Tieno(1,3)oksazin-4-oner med lipaseinhiberende aktivitet

Info

Publication number: NO20041295L
Authority: NO; Norway
Prior art keywords: tieno; oxazin; ones; inhibitory activity; lipase inhibitory
Prior art date: 2001-08-30

Application number

NO20041295A

Other languages

English (en)

Norwegian (no)

Inventor

Harold Francis Hodson

Christopher Robert Dunk

Richard Michael John Palmer

Dale Robert Mitchell

Veronique Birault

Russel George Hunt

Original Assignee

Alizyme Therapeutics Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-08-30

Filing date

2004-03-29

Publication date

2004-03-29

2001-08-30 Priority claimed from GB0121019A external-priority patent/GB0121019D0/en

2002-03-14 Priority claimed from GB0206031A external-priority patent/GB0206031D0/en

2004-03-29 Application filed by Alizyme Therapeutics Ltd filed Critical Alizyme Therapeutics Ltd

2004-03-29 Publication of NO20041295L publication Critical patent/NO20041295L/no

Links

TZBHPYXJOJGKDT-UHFFFAOYSA-N 1,3-oxazin-4-one Chemical class O=C1C=COC=N1 TZBHPYXJOJGKDT-UHFFFAOYSA-N 0.000 title 1
102000004882 Lipase Human genes 0.000 title 1
108090001060 Lipase Proteins 0.000 title 1
239000004367 Lipase Substances 0.000 title 1
230000002401 inhibitory effect Effects 0.000 title 1
235000019421 lipase Nutrition 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/14—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Diabetes (AREA)
Cardiology (AREA)
Obesity (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Urology & Nephrology (AREA)
Epidemiology (AREA)
Endocrinology (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Child & Adolescent Psychology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Emergency Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Cosmetics (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Detergent Compositions (AREA)
Coloring Foods And Improving Nutritive Qualities (AREA)
Food Preservation Except Freezing, Refrigeration, And Drying (AREA)

NO20041295A 2001-08-30 2004-03-29 Tieno(1,3)oksazin-4-oner med lipaseinhiberende aktivitet NO20041295L (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB0121019A GB0121019D0 (en)	2001-08-30	2001-08-30	/nhibitors
GB0206031A GB0206031D0 (en)	2002-03-14	2002-03-14	Inhibitors
PCT/GB2002/003903 WO2003020282A1 (en)	2001-08-30	2002-08-23	Thieno-(1,3)-oxazin-4-ones with lipase inhibiting activity

Publications (1)

Publication Number	Publication Date
NO20041295L true NO20041295L (no)	2004-03-29

Family

ID=26246489

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20041295A NO20041295L (no)	2001-08-30	2004-03-29	Tieno(1,3)oksazin-4-oner med lipaseinhiberende aktivitet

Country Status (19)

Country	Link
US (2)	US7407954B2 (de)
EP (1)	EP1446125B1 (de)
JP (2)	JP2005527469A (de)
KR (1)	KR100934256B1 (de)
CN (1)	CN1556706B (de)
AR (1)	AR036399A1 (de)
AT (1)	ATE429918T1 (de)
AU (1)	AU2002321536B2 (de)
CA (1)	CA2458213A1 (de)
DE (1)	DE60232170D1 (de)
HU (1)	HUP0401298A3 (de)
MX (1)	MXPA04001922A (de)
MY (1)	MY139608A (de)
NO (1)	NO20041295L (de)
NZ (1)	NZ531272A (de)
PL (1)	PL368994A1 (de)
RU (1)	RU2324696C2 (de)
WO (1)	WO2003020282A1 (de)
ZA (1)	ZA200401595B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN1556706B (zh) *	2001-08-30	2011-04-27	罗吉尼有限责任公司	具有脂肪酶抑制活性的噻吩并-(1,3)-噁嗪-4-酮
AU2002366810B2 (en) *	2001-12-20	2009-06-11	Osi Pharmaceuticals, Inc.	Pancreatic lipase inhibitor compounds, their synthesis and use
WO2006044826A2 (en) *	2004-10-20	2006-04-27	Compass Pharmaceuticals Llc	Thiophens and their use as anti-tumor agents

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1247547A (en)	1983-06-22	1988-12-28	Paul Hadvary	Leucine derivatives
SU1302659A1 (ru) *	1985-07-09	1991-06-07	Пермский фармацевтический институт	2-(П-Толиламинометиленамино)-6-п-толил-1,3-оксазин-4-он, про вл ющий противовоспалительную активность
DE3540377A1 (de)	1985-11-14	1987-05-21	Bayer Ag	Thienooxazinone, verfahren zu ihrer herstellung und ihre verwendung als leistungsfoerderer
IL125947A0 (en)	1997-09-17	1999-04-11	American Cyanamid Co	3-(1,2-benzisothiazol- and isoxazol-5-yl)-2,4(1h,3h)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-yl)-4(3)-pyrimidinone or thione herbicidal agents
EP0985670A1 (de)	1998-08-13	2000-03-15	American Cyanamid Company	1-(3-Heterocyclylphenyl)isothioharnstoff-, -isoharnstoff-, -guanidin- und amidinverbindungen als Herbizide
AU1375000A (en)	1998-11-26	2000-06-13	Novo Nordisk A/S	Heterocyclic compounds regulating clotting
AR022204A1 (es)	1999-01-08	2002-09-04	Norgine Bv	Compuesto, proceso para su preparacion, composicion farmaceutica y producto comestible que lo comprende.
GB9900416D0 (en)	1999-01-08	1999-02-24	Alizyme Therapeutics Ltd	Inhibitors
EP1212098A2 (de) *	1999-09-10	2002-06-12	The Procter & Gamble Company	Enzyminhibitoren
GB0001572D0 (en) *	2000-01-24	2000-03-15	Alizyme Therapeutics Ltd	Inhibitors
JP2002105081A (ja) *	2000-07-28	2002-04-10	Nikken Chem Co Ltd	新規チオフェンニ環化合物
CN1556706B (zh) *	2001-08-30	2011-04-27	罗吉尼有限责任公司	具有脂肪酶抑制活性的噻吩并-(1,3)-噁嗪-4-酮
AU2002366810B2 (en) *	2001-12-20	2009-06-11	Osi Pharmaceuticals, Inc.	Pancreatic lipase inhibitor compounds, their synthesis and use

2002
- 2002-08-23 CN CN028185900A patent/CN1556706B/zh not_active Expired - Fee Related
- 2002-08-23 DE DE60232170T patent/DE60232170D1/de not_active Expired - Lifetime
- 2002-08-23 HU HU0401298A patent/HUP0401298A3/hu unknown
- 2002-08-23 RU RU2004109588/04A patent/RU2324696C2/ru not_active IP Right Cessation
- 2002-08-23 JP JP2003524589A patent/JP2005527469A/ja not_active Withdrawn
- 2002-08-23 CA CA002458213A patent/CA2458213A1/en not_active Abandoned
- 2002-08-23 KR KR1020047002805A patent/KR100934256B1/ko not_active Expired - Fee Related
- 2002-08-23 MX MXPA04001922A patent/MXPA04001922A/es active IP Right Grant
- 2002-08-23 NZ NZ531272A patent/NZ531272A/en not_active IP Right Cessation
- 2002-08-23 AT AT02755241T patent/ATE429918T1/de not_active IP Right Cessation
- 2002-08-23 PL PL02368994A patent/PL368994A1/xx not_active Application Discontinuation
- 2002-08-23 AU AU2002321536A patent/AU2002321536B2/en not_active Ceased
- 2002-08-23 US US10/488,045 patent/US7407954B2/en not_active Expired - Fee Related
- 2002-08-23 WO PCT/GB2002/003903 patent/WO2003020282A1/en not_active Ceased
- 2002-08-23 EP EP02755241A patent/EP1446125B1/de not_active Expired - Lifetime
- 2002-08-29 MY MYPI20023211A patent/MY139608A/en unknown
- 2002-08-30 AR ARP020103295A patent/AR036399A1/es unknown
2004
- 2004-02-25 ZA ZA2004/01595A patent/ZA200401595B/en unknown
- 2004-03-29 NO NO20041295A patent/NO20041295L/no not_active Application Discontinuation
2008
- 2008-07-24 US US12/178,920 patent/US20090029978A1/en not_active Abandoned
2010
- 2010-01-29 JP JP2010019160A patent/JP2010159260A/ja not_active Ceased

Also Published As

Publication number	Publication date
CN1556706A (zh)	2004-12-22
RU2004109588A (ru)	2005-05-10
AR036399A1 (es)	2004-09-08
EP1446125B1 (de)	2009-04-29
US20050075336A1 (en)	2005-04-07
MXPA04001922A (es)	2005-03-07
RU2324696C2 (ru)	2008-05-20
US7407954B2 (en)	2008-08-05
KR100934256B1 (ko)	2009-12-28
NZ531272A (en)	2006-01-27
CA2458213A1 (en)	2003-03-13
PL368994A1 (en)	2005-04-04
JP2010159260A (ja)	2010-07-22
ATE429918T1 (de)	2009-05-15
JP2005527469A (ja)	2005-09-15
HK1064940A1 (en)	2005-02-08
US20090029978A1 (en)	2009-01-29
AU2002321536B2 (en)	2007-05-17
KR20040052216A (ko)	2004-06-22
WO2003020282A1 (en)	2003-03-13
EP1446125A1 (de)	2004-08-18
CN1556706B (zh)	2011-04-27
DE60232170D1 (de)	2009-06-10
HUP0401298A3 (en)	2008-03-28
MY139608A (en)	2009-10-30
HUP0401298A2 (hu)	2004-10-28
ZA200401595B (en)	2005-05-25

Legal Events

Date	Code	Title	Description
2012-03-26	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
IS7729A (is)	2005-03-08	Bensónaþýridín með PDE 3/4 tálmunarvirkni
BR0000327B1 (pt)	2008-11-18	cabeÇa de poÇo.
CY2014041I2 (el)	2016-07-27	2,3-διυδρο-6-νιτροϊμιδαζο 2,1 -b-οξαζολια
DK2308855T3 (da)	2013-01-28	2,4-Diaminopyrimidinderivater
ITTO20010940A0 (it)	2001-10-04	,,sedia,,
DE60026411D1 (de)	2006-05-04	Wippschalter
BR0208970B1 (pt)	2011-05-31	produto absorvente com ajuste melhorado.
BR0208971B1 (pt)	2011-04-19	produto absorvente com ajuste melhorado.
BR0208969B1 (pt)	2011-04-19	produto absorvente com ajuste melhorado.
BR0202206B1 (pt)	2013-02-05	estrutura de suspensço.
BR0201919B1 (pt)	2010-06-29	colheitadeira.
FI20001593A7 (fi)	2002-01-04	Comt-entsyymiõ inhiboivaa aktiivisuutta omaavia kumariinijohdannaisia
NO20040387L (no)	2004-03-24	Nedihullsfrigjoringskopling.
IT1316059B1 (it)	2003-03-28	Depigmentanti cutanei.
EP1461621A4 (de)	2005-11-23	Enzymaktivitätsprofile
IT1310418B1 (it)	2002-02-13	Bracciale biorigenerante.
PL368994A1 (en)	2005-04-04	Thieno-(1,3)-oxazin-4-ones with lipase inhibiting activity
ES1048400Y (es)	2001-12-16	Bota-patin mejorada.
BR0103827B1 (pt)	2012-08-21	cola - pds.
ES1050481Y (es)	2002-11-16	Pieza de construccion.
ES1050769Y (es)	2002-09-16	Galleta perfeccionada.
ITMI20011465A0 (it)	2001-07-10	Gene ad attivita' oncosoppressiva
NL1015318A1 (nl)	2001-03-05	Verzekeren per kilo.
ES1044252Y (es)	2000-09-01	Cabezal embuchador.
ES1048216Y (es)	2001-12-01	Tapon-precinto perfeccionado.