NO20041618L - Legemidler omfattende en kombinasjon av triazaspiro[5,5]undekanderivat med cytokrom P450 isozyn 3A4 inhibitor og/eller P-glykoproeininhibitor - Google Patents

Legemidler omfattende en kombinasjon av triazaspiro[5,5]undekanderivat med cytokrom P450 isozyn 3A4 inhibitor og/eller P-glykoproeininhibitor

Info

Publication number: NO20041618L
Authority: NO; Norway
Prior art keywords: inhibitor; isozyn; triazaspiro; cytochrome; drugs
Prior art date: 2001-10-23

Application number

NO20041618A

Other languages

English (en)

Norwegian (no)

Inventor

Shiro Shibayama

Yoshikazu Takaoka

Haruo Imawaka

Original Assignee

Ono Pharmaceutical Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-10-23

Filing date

2004-04-21

Publication date

2004-07-22

2004-04-21 Application filed by Ono Pharmaceutical Co filed Critical Ono Pharmaceutical Co

2004-07-22 Publication of NO20041618L publication Critical patent/NO20041618L/no

Links

102000002004 Cytochrome P-450 Enzyme System Human genes 0.000 title 1
108010015742 Cytochrome P-450 Enzyme System Proteins 0.000 title 1
229940049937 Pgp inhibitor Drugs 0.000 title 1
239000003814 drug Substances 0.000 title 1
229940079593 drug Drugs 0.000 title 1
239000002748 glycoprotein P inhibitor Substances 0.000 title 1
239000003112 inhibitor Substances 0.000 title 1
108091006086 inhibitor proteins Proteins 0.000 title 1
RSJKGSCJYJTIGS-BJUDXGSMSA-N undecane Chemical class CCCCCCCCCC[11CH3] RSJKGSCJYJTIGS-BJUDXGSMSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/499—Spiro-condensed pyrazines or piperazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A61P31/08—Antibacterial agents for leprosy
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- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
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- A61P9/06—Antiarrhythmics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Oncology (AREA)
Diabetes (AREA)
Immunology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Communicable Diseases (AREA)
Cardiology (AREA)
Epidemiology (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Endocrinology (AREA)
Psychiatry (AREA)
Hematology (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Physical Education & Sports Medicine (AREA)
Dermatology (AREA)
Obesity (AREA)
Virology (AREA)
Anesthesiology (AREA)
Reproductive Health (AREA)
Transplantation (AREA)
Gastroenterology & Hepatology (AREA)

NO20041618A 2001-10-23 2004-04-21 Legemidler omfattende en kombinasjon av triazaspiro[5,5]undekanderivat med cytokrom P450 isozyn 3A4 inhibitor og/eller P-glykoproeininhibitor NO20041618L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2001324435		2001-10-23
PCT/JP2002/002552 WO2003035074A1 (en)	2001-10-23	2002-03-18	Drugs comprising combination of triazaspiro[5,5]undecane derivative with cytochrome p450 isozyme 3a4 inhibitor and/or p-glycoprotein inhibitor

Publications (1)

Publication Number	Publication Date
NO20041618L true NO20041618L (no)	2004-07-22

Family

ID=19141164

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20041618A NO20041618L (no)	2001-10-23	2004-04-21	Legemidler omfattende en kombinasjon av triazaspiro[5,5]undekanderivat med cytokrom P450 isozyn 3A4 inhibitor og/eller P-glykoproeininhibitor

Country Status (15)

Country	Link
EP (1)	EP1438962A4 (pl)
JP (1)	JPWO2003035074A1 (pl)
KR (1)	KR20040045882A (pl)
CN (1)	CN1571671A (pl)
BR (1)	BR0213372A (pl)
CA (1)	CA2461545A1 (pl)
CZ (1)	CZ2004500A3 (pl)
HU (1)	HUP0500028A2 (pl)
IL (1)	IL161053A0 (pl)
MX (1)	MXPA04003816A (pl)
NO (1)	NO20041618L (pl)
PL (1)	PL370280A1 (pl)
RU (1)	RU2004115621A (pl)
WO (1)	WO2003035074A1 (pl)
ZA (1)	ZA200403086B (pl)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1541573A4 (en)	2002-09-18	2007-05-02	Ono Pharmaceutical Co	NEW CRYSTALS OF DERIVATIVE TRIAZASPIRO 5.5 \| UNDECANES
PL376154A1 (pl) *	2002-09-18	2005-12-27	Ono Pharmaceutical Co, Ltd.	Pochodne triazaspiro[5.5]undekanu i leki zawierające te pochodne jako składnik aktywny
US20070155713A1 (en) *	2003-04-21	2007-07-05	Rena Nishizawa	Nitrogen-containing heterocyclic compounds and use thereof
EP1865967A4 (en) *	2005-04-08	2011-02-09	Chimerix Inc	COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING VIRAL INFECTIONS AND OTHER DISEASES
WO2006110655A2 (en)	2005-04-08	2006-10-19	Chimerix, Inc.	Compounds, compositions and methods for the treatment of poxvirus infections
EP1889622A4 (en) *	2005-05-31	2009-12-23	Ono Pharmaceutical Co	SPIROPIPERIDINE COMPOUND AND MEDICINAL USE THEREOF
KR100709555B1 (ko) *	2005-09-29	2007-04-20	한국과학기술연구원	고성능 액체크로마토그래피-질량분석기를 이용한 혈장 중의에이즈 치료제 검출 방법
WO2009094190A2 (en)	2008-01-25	2009-07-30	Chimerix, Inc.	Methods of treating viral infections
WO2011011519A1 (en)	2009-07-21	2011-01-27	Chimerix, Inc.	Compounds, compositions and methods for treating ocular conditions
EP3216789A1 (en)	2010-02-12	2017-09-13	Chimerix, Inc.	Methods of treating viral infection
CA2797601A1 (en)	2010-04-26	2011-11-10	Chimerix, Inc.	Methods of treating retroviral infections and related dosage regimes
CN104535774B (zh) *	2015-01-16	2017-04-19	中国药科大学	一种炎性肠病状态下药物敏感性的新检测指标及其在药物治疗方案设计中的应用
KR102203334B1 (ko)	2019-04-12	2021-01-15	성균관대학교산학협력단	피모자이드의 항암제 병용요법
WO2024223797A1 (en)	2023-04-28	2024-10-31	Institut National de la Santé et de la Recherche Médicale	Use of cyp3a4 inhibitors for the treatment of hepatitis d virus (hdv) infections

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5567592A (en) *	1994-02-02	1996-10-22	Regents Of The University Of California	Screening method for the identification of bioenhancers through the inhibition of P-glycoprotein transport in the gut of a mammal
AU780419C (en) *	1999-12-03	2005-09-29	Ono Pharmaceutical Co. Ltd.	Triazaspiro(5.5)undecane derivatives and drugs containing the same as the active ingredient

2002
- 2002-03-18 PL PL02370280A patent/PL370280A1/pl unknown
- 2002-03-18 CN CNA028203917A patent/CN1571671A/zh active Pending
- 2002-03-18 CZ CZ2004500A patent/CZ2004500A3/cs unknown
- 2002-03-18 WO PCT/JP2002/002552 patent/WO2003035074A1/ja not_active Ceased
- 2002-03-18 RU RU2004115621/15A patent/RU2004115621A/ru not_active Application Discontinuation
- 2002-03-18 BR BR0213372-5A patent/BR0213372A/pt not_active Application Discontinuation
- 2002-03-18 MX MXPA04003816A patent/MXPA04003816A/es unknown
- 2002-03-18 EP EP02705299A patent/EP1438962A4/en not_active Withdrawn
- 2002-03-18 HU HU0500028A patent/HUP0500028A2/hu unknown
- 2002-03-18 IL IL16105302A patent/IL161053A0/xx unknown
- 2002-03-18 JP JP2003537641A patent/JPWO2003035074A1/ja not_active Withdrawn
- 2002-03-18 KR KR10-2004-7005835A patent/KR20040045882A/ko not_active Withdrawn
- 2002-03-18 CA CA002461545A patent/CA2461545A1/en not_active Abandoned
2004
- 2004-04-21 NO NO20041618A patent/NO20041618L/no not_active Application Discontinuation
- 2004-04-22 ZA ZA200403086A patent/ZA200403086B/xx unknown

Also Published As

Publication number	Publication date
CZ2004500A3 (cs)	2005-03-16
HUP0500028A2 (hu)	2005-04-28
CA2461545A1 (en)	2003-05-01
IL161053A0 (en)	2004-08-31
BR0213372A (pt)	2005-02-01
JPWO2003035074A1 (ja)	2005-02-10
WO2003035074A1 (en)	2003-05-01
MXPA04003816A (es)	2004-07-30
PL370280A1 (pl)	2005-05-16
EP1438962A1 (en)	2004-07-21
KR20040045882A (ko)	2004-06-02
ZA200403086B (en)	2005-05-11
EP1438962A4 (en)	2005-11-09
CN1571671A (zh)	2005-01-26
RU2004115621A (ru)	2005-03-27

Legal Events

Date	Code	Title	Description
2005-11-14	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
AU2002338336A1 (en)	2002-10-21	Epothilone derivatives and methods for making and using the same
AU2002353959A1 (en)	2003-05-12	Foldable and remotely imageable balloon
NO20041618L (no)	2004-07-22	Legemidler omfattende en kombinasjon av triazaspiro[5,5]undekanderivat med cytokrom P450 isozyn 3A4 inhibitor og/eller P-glykoproeininhibitor
IL161517A0 (en)	2004-09-27	6-hydroxy isoflavones, derivatives and medicaments involving same
AU2001266583A1 (en)	2001-12-11	Epothilone derivatives and methods for making and using the same
AU2001262221A1 (en)	2001-11-07	Novel epothilone derivatives, method for the preparation thereof and their pharmaceutical use
IL166100A0 (en)	2006-01-15	7,8,9-10-tetrahydro-6h-azepino,6,7,8,9-tetrahydro-pyrido and 2,3-dihydro-2h-pyrroloÄ2,1-bÜ quinazolinone derivatives
WO2002074042A3 (en)	2003-02-27	Combinations comprising an antidiarrheal agent and an epothilone or an epothilone derivative
AU2002351764A1 (en)	2003-04-22	Flavonoid compounds and their pharmaceutical uses
AU2001281307A1 (en)	2002-01-21	Fluorescein-based metal sensors, and methods of making and using the same
AU2003254803A1 (en)	2004-03-19	Sliding part and method of manufacturing the sliding part
AU2003265231A1 (en)	2003-12-19	Molecular actuators, and methods of use thereof
MXPA03009057A (es)	2004-02-12	Derivados de beta-carbolina y su uso farmaceutico contra depresion y ansiedad.
AU2003270680A1 (en)	2004-04-19	Tubular structures and methods for making the same
DE60227657D1 (de)	2008-08-28	1-OXA-3,9-DIAZASPIROc5.5ÜUNDECAN-2-ONDERIVATE UND ZEPTORS
ATE505459T1 (de)	2011-04-15	Dibenzoäb,füazepin-derivate und ihre herstellung
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