NO20042719L - Substituerte 2-amino-cykloalkankarboksamider og deres anvendelse som protease-inhibitorer - Google Patents

Substituerte 2-amino-cykloalkankarboksamider og deres anvendelse som protease-inhibitorer

Info

Publication number
NO20042719L
NO20042719L NO20042719A NO20042719A NO20042719L NO 20042719 L NO20042719 L NO 20042719L NO 20042719 A NO20042719 A NO 20042719A NO 20042719 A NO20042719 A NO 20042719A NO 20042719 L NO20042719 L NO 20042719L
Authority
NO
Norway
Prior art keywords
cycloalkanecarboxamides
amino
substituted
protease inhibitors
protease
Prior art date
Application number
NO20042719A
Other languages
English (en)
Inventor
David Bernard Smith
Thomas Gabriel
Nancy Elisabeth Krauss
Taraneh Mirzadegan
Wylie Solang Palmer
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO20042719L publication Critical patent/NO20042719L/no

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    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
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    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
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  • Organic Chemistry (AREA)
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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
NO20042719A 2001-12-04 2004-06-28 Substituerte 2-amino-cykloalkankarboksamider og deres anvendelse som protease-inhibitorer NO20042719L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33675001P 2001-12-04 2001-12-04
PCT/EP2002/013221 WO2003048123A1 (en) 2001-12-04 2002-11-25 Substituted 2-amino-cycloalkanecarboxamides and their use as cysteine protease inhibitors

Publications (1)

Publication Number Publication Date
NO20042719L true NO20042719L (no) 2004-06-28

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NO20042719A NO20042719L (no) 2001-12-04 2004-06-28 Substituerte 2-amino-cykloalkankarboksamider og deres anvendelse som protease-inhibitorer

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US (1) US6747053B2 (no)
EP (1) EP1453801B1 (no)
JP (1) JP2005517640A (no)
KR (1) KR20050044660A (no)
CN (1) CN1315806C (no)
AR (1) AR037683A1 (no)
AT (1) ATE357432T1 (no)
AU (1) AU2002352126A1 (no)
BR (1) BR0214642A (no)
CA (1) CA2467435A1 (no)
DE (1) DE60219068T2 (no)
ES (1) ES2282497T3 (no)
GT (1) GT200200253A (no)
HU (1) HUP0402344A2 (no)
IL (1) IL161992A0 (no)
MX (1) MXPA04005263A (no)
NO (1) NO20042719L (no)
PA (1) PA8559701A1 (no)
PE (1) PE20030723A1 (no)
PL (1) PL370766A1 (no)
RU (1) RU2004120784A (no)
TW (1) TW200303861A (no)
UY (1) UY27561A1 (no)
WO (1) WO2003048123A1 (no)
ZA (1) ZA200404343B (no)

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EP1147214B1 (en) * 1999-01-13 2011-01-05 The Research Foundation Of State University Of New York A novel method for designing protein kinase inhibitors
US7005445B2 (en) * 2001-10-22 2006-02-28 The Research Foundation Of State University Of New York Protein kinase and phosphatase inhibitors and methods for designing them
GB0128996D0 (en) 2001-12-04 2002-01-23 Novartis Ag Organic compounds
DE60305446T4 (de) * 2002-01-07 2009-07-09 Eisai R&D Management Co., Ltd. Desazapurine und deren verwendung
SE0203712D0 (sv) 2002-12-13 2002-12-13 Astrazeneca Ab Novel compounds
GB0403038D0 (en) 2004-02-11 2004-03-17 Novartis Ag Organic compounds
US20090226552A1 (en) * 2004-07-22 2009-09-10 Colorado State University Research Foundation Agents and methods for diagnosing osteoarthritis
AU2006261954A1 (en) * 2005-06-28 2007-01-04 Merck & Co., Inc. Non-nucleoside reverse transcriptase inhibitors
EP1749822B1 (en) * 2005-08-05 2008-10-15 Hybrigenics S.A. Novel cysteine protease inhibitors and their therapeutic applications
RU2424234C2 (ru) * 2005-08-05 2011-07-20 Ибриженикс Са Новые ингибиторы цистеиновых протеаз и их терапевтическое применение
WO2007041775A1 (en) * 2005-10-10 2007-04-19 The University Of Queensland Cysteine protease inhibitors incorporating azide groups
WO2007081530A2 (en) * 2006-01-03 2007-07-19 Med Institute, Inc. Endoluminal medical device for local delivery of cathepsin inhibitors
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KR20050044660A (ko) 2005-05-12
US20030212097A1 (en) 2003-11-13
DE60219068T2 (de) 2007-12-13
IL161992A0 (en) 2005-11-20
RU2004120784A (ru) 2005-08-10
EP1453801A1 (en) 2004-09-08
GT200200253A (es) 2003-07-03
BR0214642A (pt) 2004-11-03
ES2282497T3 (es) 2007-10-16
PL370766A1 (en) 2005-05-30
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US6747053B2 (en) 2004-06-08
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ATE357432T1 (de) 2007-04-15
CN1639119A (zh) 2005-07-13
AU2002352126A1 (en) 2003-06-17
CN1315806C (zh) 2007-05-16
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TW200303861A (en) 2003-09-16
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HUP0402344A2 (hu) 2005-02-28
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