NO20042731L - Fremgangsmater for rensing av levofloxacin - Google Patents

Fremgangsmater for rensing av levofloxacin

Info

Publication number
NO20042731L
NO20042731L NO20042731A NO20042731A NO20042731L NO 20042731 L NO20042731 L NO 20042731L NO 20042731 A NO20042731 A NO 20042731A NO 20042731 A NO20042731 A NO 20042731A NO 20042731 L NO20042731 L NO 20042731L
Authority
NO
Norway
Prior art keywords
levofloxacin
purifying
methods
purified
antioxidant
Prior art date
Application number
NO20042731A
Other languages
English (en)
Norwegian (no)
Inventor
Valerie Niddam-Hildesheim
Neomi Gershon
Eduard Schwartz
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/263,192 external-priority patent/US7629458B2/en
Application filed by Teva Pharma filed Critical Teva Pharma
Publication of NO20042731L publication Critical patent/NO20042731L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
NO20042731A 2001-11-29 2004-06-29 Fremgangsmater for rensing av levofloxacin NO20042731L (no)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US33431601P 2001-11-29 2001-11-29
US35493902P 2002-02-11 2002-02-11
US26296502A 2002-10-03 2002-10-03
US10/263,192 US7629458B2 (en) 2001-10-03 2002-10-03 Preparation of levofloxacin and hemihydrate thereof
PCT/US2002/038182 WO2003045329A2 (en) 2001-11-29 2002-11-27 Methods for the purification of levofloxacin

Publications (1)

Publication Number Publication Date
NO20042731L true NO20042731L (no) 2004-06-29

Family

ID=31892240

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20042731A NO20042731L (no) 2001-11-29 2004-06-29 Fremgangsmater for rensing av levofloxacin

Country Status (13)

Country Link
EP (1) EP1460997A4 (is)
JP (3) JP2005527484A (is)
CN (1) CN1596256A (is)
AU (1) AU2002365416A1 (is)
CA (1) CA2466860A1 (is)
HR (1) HRP20040546A2 (is)
HU (1) HUP0500285A3 (is)
IL (1) IL162172A0 (is)
IS (1) IS7288A (is)
MX (1) MXPA04005196A (is)
NO (1) NO20042731L (is)
PL (1) PL374558A1 (is)
WO (1) WO2003045329A2 (is)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7629458B2 (en) 2001-10-03 2009-12-08 Teva Pharmaceutical Industries Ltd. Preparation of levofloxacin and hemihydrate thereof
AU2003285625A1 (en) * 2002-12-16 2004-07-09 Ranbaxy Laboratories Limited Pure levofloxacin hemihydrate and processes for preparation thereof
KR100704641B1 (ko) * 2004-07-21 2007-04-06 주식회사유한양행 고순도의 레보플록사신 제조방법
JP2006273718A (ja) * 2005-03-28 2006-10-12 Shiono Chemical Co Ltd レボフロキサシン・１／２水和物の製法
CN1321121C (zh) * 2005-04-21 2007-06-13 浙江医药股份有限公司新昌制药厂 左氧氟沙星制备及后处理方法
US7964723B2 (en) * 2008-08-02 2011-06-21 Apeloa-Kangyu And practical process for exclusively producing (S)-9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido-[1,2,3,de][1,4]benzoxazine-6-carboxylic acid hemihydrate
CN102070650B (zh) * 2011-01-28 2012-06-27 山东省药品检验所 左氧氟沙星-n-氧化物的制备方法
US20120251685A1 (en) * 2011-04-04 2012-10-04 Martek Biosciences Corporation Oil-in-Water Emulsions Comprising a Polyunsaturated Fatty Acid and Methods of Making the Same
CN105823851A (zh) * 2015-12-15 2016-08-03 浙江海洋学院 一种检测海水中氧氟沙星对映体的方法
CN108218892A (zh) * 2018-03-16 2018-06-29 乐山职业技术学院 一种左氧氟沙星的纯化方法
CN112174981A (zh) * 2020-11-03 2021-01-05 深圳市祥根生物科技有限公司 一种左氧氟沙星脱氟杂质的制备方法
CN114507242B (zh) * 2022-01-26 2023-05-19 上虞京新药业有限公司 高光学纯度左氧氟沙星的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK170473B1 (da) * 1985-06-20 1995-09-11 Daiichi Seiyaku Co S(-)-pyridobenzoxazinforbindelser
US5237060A (en) * 1985-12-10 1993-08-17 Bayer Aktiengesellschaft Process of preparing enantiomerically pure 1,8-bridged 4-quinolone-3-carboxylic acids
TW208013B (is) * 1990-03-01 1993-06-21 Daiichi Co Ltd
JPH07501835A (ja) * 1992-10-07 1995-02-23 デリバドス・デル・エチロ・ソシエダッド・アノニマ オフロキサジン，レボフロキサジン及び誘導体の合成に使用されるベンゾキサジンの製造法
KR0125115B1 (ko) * 1994-03-22 1997-12-05 김은영 (-)피페라진 벤즈옥사진 유도체의 제조방법
KR100309871B1 (ko) * 1999-02-24 2001-10-29 윤종용 (-)피리도벤즈옥사진 카르복실산 유도체의 제조방법
US7629458B2 (en) * 2001-10-03 2009-12-08 Teva Pharmaceutical Industries Ltd. Preparation of levofloxacin and hemihydrate thereof

Also Published As

Publication number Publication date
HUP0500285A2 (hu) 2005-06-28
JP2006219496A (ja) 2006-08-24
IL162172A0 (en) 2005-11-20
EP1460997A4 (en) 2005-06-15
IS7288A (is) 2004-06-21
WO2003045329A3 (en) 2004-02-19
CN1596256A (zh) 2005-03-16
AU2002365416A1 (en) 2003-06-10
EP1460997A2 (en) 2004-09-29
CA2466860A1 (en) 2003-06-05
JP2005527484A (ja) 2005-09-15
PL374558A1 (en) 2005-10-31
MXPA04005196A (es) 2005-11-23
JP2008007517A (ja) 2008-01-17
HUP0500285A3 (en) 2009-03-30
WO2003045329A2 (en) 2003-06-05
HRP20040546A2 (en) 2004-10-31

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