NO20043585L - Behandling av reumatoid artritt - Google Patents

Behandling av reumatoid artritt

Info

Publication number
NO20043585L
NO20043585L NO20043585A NO20043585A NO20043585L NO 20043585 L NO20043585 L NO 20043585L NO 20043585 A NO20043585 A NO 20043585A NO 20043585 A NO20043585 A NO 20043585A NO 20043585 L NO20043585 L NO 20043585L
Authority
NO
Norway
Prior art keywords
treatment
rheumatoid arthritis
formula
pharmaceutically acceptable
acceptable salt
Prior art date
Application number
NO20043585A
Other languages
English (en)
Other versions
NO328255B1 (no
Inventor
Heikki Joensuu
Original Assignee
Hyks Inst Ti Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hyks Inst Ti Oy filed Critical Hyks Inst Ti Oy
Publication of NO20043585L publication Critical patent/NO20043585L/no
Publication of NO328255B1 publication Critical patent/NO328255B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
  • Liquid Crystal Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO20043585A 2002-01-28 2004-08-27 Anvendelsen av 4-(4-metylpiperazin-1-ylmetyl)-N-[4-metyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)fenyl]-benzamid og kombinasjoner av denne forbindelsen for fremstilling av preparater for behandling av reumatoid artritt. NO328255B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0201882.8A GB0201882D0 (en) 2002-01-28 2002-01-28 Organic compounds
PCT/EP2003/000802 WO2003063844A2 (en) 2002-01-28 2003-01-27 Treatment of rheumatoid arthritis using imatinie

Publications (2)

Publication Number Publication Date
NO20043585L true NO20043585L (no) 2004-10-21
NO328255B1 NO328255B1 (no) 2010-01-18

Family

ID=9929858

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20043585A NO328255B1 (no) 2002-01-28 2004-08-27 Anvendelsen av 4-(4-metylpiperazin-1-ylmetyl)-N-[4-metyl-3-(4-pyridin-3-yl)pyrimidin-2-ylamino)fenyl]-benzamid og kombinasjoner av denne forbindelsen for fremstilling av preparater for behandling av reumatoid artritt.

Country Status (22)

Country Link
US (2) US20060264443A1 (no)
EP (1) EP1471916B1 (no)
JP (1) JP4398731B2 (no)
KR (1) KR101030416B1 (no)
CN (1) CN1646130A (no)
AT (1) ATE399555T1 (no)
BR (1) BR0307286A (no)
CA (1) CA2473158C (no)
DE (1) DE60321888D1 (no)
DK (1) DK1471916T3 (no)
ES (1) ES2309299T3 (no)
GB (1) GB0201882D0 (no)
IL (1) IL162983A (no)
MX (1) MXPA04007309A (no)
NO (1) NO328255B1 (no)
NZ (1) NZ534137A (no)
PL (1) PL212137B1 (no)
PT (1) PT1471916E (no)
RU (1) RU2322238C2 (no)
SI (1) SI1471916T1 (no)
WO (1) WO2003063844A2 (no)
ZA (1) ZA200405323B (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060128720A1 (en) * 2002-03-21 2006-06-15 Kufe Donald W Inhibition of cell death responses induced by oxidative stress
US20050130986A1 (en) * 2003-11-21 2005-06-16 Eklund Kari K. Treatment of spondylarthropathies
ATE546733T1 (de) * 2004-09-08 2012-03-15 Immunaid Pty Ltd Therapiestrategie zur behandlung von autoimmunkrankheiten und degenerativen erkrankungen
JP2010500283A (ja) * 2006-05-31 2010-01-07 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー チロシンキナーゼ阻害剤を用いて炎症性疾患を治療する方法
CN102512421B (zh) * 2011-10-28 2013-11-06 中国科学院广州生物医药与健康研究院 哌嗪酰胺类化合物在制药中的应用
KR101386697B1 (ko) 2012-06-18 2014-04-18 아주대학교산학협력단 이매티닙 또는 이의 약학적으로 허용되는 염을 유효성분으로 포함하는 혈관 투과성 관련 질환의 치료 또는 예방용 조성물
RU2580656C1 (ru) * 2014-11-20 2016-04-10 Закрытое Акционерное Общество "БИОКОМ" Твердая лекарственная форма гидроксихлорохина немедленного высвобождения и способ ее получения
CN113039203A (zh) * 2018-10-18 2021-06-25 中国抗体制药有限公司 通过破坏siglec型抗原的顺式配体结合调节自身免疫的方法
US11977085B1 (en) 2023-09-05 2024-05-07 Elan Ehrlich Date rape drug detection device and method of using same

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4316884A (en) * 1979-01-25 1982-02-23 Adria Laboratories, Inc. Sustained release pharmaceutical formulation
US5521184A (en) * 1992-04-03 1996-05-28 Ciba-Geigy Corporation Pyrimidine derivatives and processes for the preparation thereof
US5792476A (en) * 1996-12-19 1998-08-11 Abigo Medical Ab Sustained release glucocorticoid pharmaceutical composition
CO4940418A1 (es) 1997-07-18 2000-07-24 Novartis Ag Modificacion de cristal de un derivado de n-fenil-2- pirimidinamina, procesos para su fabricacion y su uso
TW550258B (en) * 1999-05-31 2003-09-01 Hoffmann La Roche 4-phenyl-pyrimidine derivatives
CO5200760A1 (es) * 1999-06-16 2002-09-27 Smithkline Beecham Corp Antagonistas del receptor de la il-8 ceptor il-8
GB0108606D0 (en) * 2001-04-05 2001-05-23 Novartis Ag Organic compounds
CA2444840A1 (en) * 2001-04-16 2002-10-24 Uab Research Foundation Akt and regulation of ra synovial fibroblast apoptosis
BR0209647A (pt) * 2001-05-16 2004-07-27 Novartis Ag Combinação que compreende n-{5-[4-(4-metil-piperazino-metil)-benzoilamido]-2-metil fenil}-4-(3-piridil)-2-pirimidina-amina e um agente quimioterapêutico
CA2452169A1 (en) * 2001-06-29 2003-01-09 Ab Science Use of tyrosine kinase inhibitors for treating inflammatory diseases

Also Published As

Publication number Publication date
NO328255B1 (no) 2010-01-18
ZA200405323B (en) 2005-08-31
CN1646130A (zh) 2005-07-27
DE60321888D1 (no) 2008-08-14
ES2309299T3 (es) 2008-12-16
US20060264443A1 (en) 2006-11-23
CA2473158A1 (en) 2003-08-07
BR0307286A (pt) 2004-12-28
JP4398731B2 (ja) 2010-01-13
PL370264A1 (en) 2005-05-16
KR101030416B1 (ko) 2011-04-20
WO2003063844A3 (en) 2004-04-01
KR20040086301A (ko) 2004-10-08
MXPA04007309A (es) 2005-09-12
NZ534137A (en) 2007-03-30
US20090131382A1 (en) 2009-05-21
PL212137B1 (pl) 2012-08-31
EP1471916B1 (en) 2008-07-02
CA2473158C (en) 2013-06-11
HK1072192A1 (en) 2005-08-19
DK1471916T3 (da) 2008-10-20
RU2004126447A (ru) 2005-07-10
GB0201882D0 (en) 2002-03-13
SI1471916T1 (sl) 2008-12-31
IL162983A (en) 2010-06-16
WO2003063844A2 (en) 2003-08-07
JP2005526022A (ja) 2005-09-02
PT1471916E (pt) 2008-10-03
EP1471916A2 (en) 2004-11-03
RU2322238C2 (ru) 2008-04-20
ATE399555T1 (de) 2008-07-15

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