NO20050917L - Thiomolybdatanaloger og anvendelser derav - Google Patents
Thiomolybdatanaloger og anvendelser deravInfo
- Publication number
- NO20050917L NO20050917L NO20050917A NO20050917A NO20050917L NO 20050917 L NO20050917 L NO 20050917L NO 20050917 A NO20050917 A NO 20050917A NO 20050917 A NO20050917 A NO 20050917A NO 20050917 L NO20050917 L NO 20050917L
- Authority
- NO
- Norway
- Prior art keywords
- thiomolybdate
- analogues
- applications
- derivatives
- dysregulation
- Prior art date
Links
- CXVCSRUYMINUSF-UHFFFAOYSA-N tetrathiomolybdate(2-) Chemical class [S-][Mo]([S-])(=S)=S CXVCSRUYMINUSF-UHFFFAOYSA-N 0.000 title abstract 3
- 208000029011 Copper metabolism disease Diseases 0.000 abstract 2
- 208000008589 Obesity Diseases 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 230000008482 dysregulation Effects 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 2
- 235000020824 obesity Nutrition 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F11/00—Compounds containing elements of Groups 6 or 16 of the Periodic Table
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
- C07D213/20—Quaternary compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/62—Quaternary ammonium compounds
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/62—Quaternary ammonium compounds
- C07C211/63—Quaternary ammonium compounds having quaternised nitrogen atoms bound to acyclic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/62—Quaternary ammonium compounds
- C07C211/64—Quaternary ammonium compounds having quaternised nitrogen atoms bound to carbon atoms of six-membered aromatic rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/40—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton with quaternised nitrogen atoms bound to carbon atoms of the carbon skeleton
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/08—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C219/04—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C219/06—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having the hydroxy groups esterified by carboxylic acids having the esterifying carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms of an acyclic saturated carbon skeleton
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
- C07C229/54—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C229/60—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring with amino and carboxyl groups bound in meta- or para- positions
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C317/28—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/53—Nitrogen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/037—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements with quaternary ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Endocrinology (AREA)
- Nutrition Science (AREA)
- Child & Adolescent Psychology (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Reproductive Health (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/202,346 US20040019043A1 (en) | 2002-07-23 | 2002-07-23 | Thiomolybdate analogues and uses thereof |
| US43474202P | 2002-12-18 | 2002-12-18 | |
| US43695803A | 2003-05-12 | 2003-05-12 | |
| US10/447,585 US7189865B2 (en) | 2002-07-23 | 2003-05-28 | Thiomolybdate analogues and uses thereof |
| PCT/US2003/023031 WO2004009034A2 (fr) | 2002-07-23 | 2003-07-22 | Analogues de thiomolybdate et leurs utilisations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20050917L true NO20050917L (no) | 2005-04-20 |
Family
ID=30773643
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20050917A NO20050917L (no) | 2002-07-23 | 2005-02-21 | Thiomolybdatanaloger og anvendelser derav |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US7189865B2 (fr) |
| EP (1) | EP1556029B1 (fr) |
| JP (1) | JP2006506466A (fr) |
| KR (1) | KR20050053596A (fr) |
| CN (1) | CN100531732C (fr) |
| AU (1) | AU2003256704A1 (fr) |
| BR (1) | BR0312851A (fr) |
| CA (1) | CA2493127A1 (fr) |
| DK (1) | DK1556029T3 (fr) |
| EA (1) | EA200500250A1 (fr) |
| ES (1) | ES2448800T3 (fr) |
| HR (1) | HRP20050174A2 (fr) |
| IL (1) | IL166448A0 (fr) |
| MX (1) | MXPA05000870A (fr) |
| NO (1) | NO20050917L (fr) |
| PL (1) | PL374821A1 (fr) |
| PT (1) | PT1556029E (fr) |
| SI (1) | SI1556029T1 (fr) |
| WO (1) | WO2004009034A2 (fr) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000018392A1 (fr) * | 1998-09-25 | 2000-04-06 | Glycox Corporation Limited | Fructosamine-oxydase: antagonistes et inhibiteurs |
| WO2000066587A2 (fr) * | 1999-04-30 | 2000-11-09 | Slil Biomedical Corporation | Analogues de polyamine a conformation restreinte utilises pour traiter des maladies |
| MXPA01011008A (es) * | 1999-04-30 | 2003-06-30 | Slil Biomedical Corp | Conjugados analogos de poliamina y conjugados de quinona novedosos como terapia para canceres y enfermedades de la prostata. |
| WO2002091989A2 (fr) * | 2000-11-08 | 2002-11-21 | Slil Biomedical Corporation | Therapies antivirales a base de conjugues d'acides amines a une polyamine ou a des analogues de polyamine |
| EP1471931A4 (fr) * | 2001-08-24 | 2006-06-14 | Maine Medical Ct Res Inst | Export non traditionnel de cytokines pro-inflammatoires dependant du cuivre et methodes, compositions et kits associes |
| WO2003033455A1 (fr) * | 2001-10-16 | 2003-04-24 | Slil Biomedical Corporation | Composes oligoamine et leurs derives pour le traitement des cancers |
| EP2500018B1 (fr) | 2002-03-08 | 2017-07-19 | PhilERA New Zealand Limited | Prévention et/ou traitement des maladies cardio-vasculaires et/ou insuffisances cardiaques associées |
| US6855340B2 (en) * | 2002-05-24 | 2005-02-15 | Regents Of The University Of Michigan | Copper lowering treatment of inflammatory and fibrotic diseases |
| GEP20074270B (en) * | 2002-07-23 | 2007-12-25 | Univ Michigan | Tetrapropylammonium tetrathiomolybdate and related compounds for anti-angiogenic therapies |
| US20060100278A1 (en) | 2002-08-20 | 2006-05-11 | Cooper Garth J S | Dosage forms and related therapies |
| EA200501865A1 (ru) * | 2003-05-27 | 2006-08-25 | Атеньюон, Ллк | Аналоги тиовольфраматов и их применение |
| EP1729784A1 (fr) * | 2004-02-23 | 2006-12-13 | Attenuon, LLC | Formulations de composés de thiomolybdate ou de thiotungstate et leurs utilisations |
| WO2005083107A2 (fr) * | 2004-02-24 | 2005-09-09 | Attenuon Llp | Inhibition de la superoxyde-dismutase par le tetrathiomolybdate : identification de nouveaux agents anti-angiogeniques et de nouveaux agents antitumoraux |
| EP1778618B1 (fr) | 2004-07-19 | 2013-12-25 | PhilERA New Zealand Limited | Synthese de triethylenetetramines |
| JP5099620B2 (ja) * | 2006-10-26 | 2012-12-19 | 学校法人日本大学 | 筋萎縮性側索硬化症治療薬 |
| EP2117315A1 (fr) * | 2007-02-21 | 2009-11-18 | SSV Therapeutics, Inc. | Adamantanamines et sels de néramexane d'acides thiomolybdiques et thiotungsténiques |
| PL381862A1 (pl) | 2007-02-28 | 2008-09-01 | Trigendo Spółka Z Ograniczoną Odpowiedzialnością | Zastosowanie związków pirydyniowych i sposób leczenia |
| US20090028800A1 (en) * | 2007-07-27 | 2009-01-29 | Peeples William H | Method of Treating Postpartum Depression and Aggression |
| US20110028513A1 (en) * | 2008-03-31 | 2011-02-03 | Lang Zhuo | Method for treating neurological disorders with imidazolium and imidazolinium compounds |
| JP6285164B2 (ja) * | 2013-12-05 | 2018-02-28 | デクセリアルズ株式会社 | 化合物、熱硬化性樹脂組成物、及び熱硬化性シート |
| ES2956768T3 (es) * | 2016-02-23 | 2023-12-27 | Vanderbilt Chemicals Llc | Sales de molibdato binucleares que contienen azufre de amonio cuaternario como aditivos de lubricantes |
| EP3720433B1 (fr) | 2017-12-04 | 2022-02-02 | Alexion Pharmaceuticals, Inc. | Bis-choline tétrathiomolybdate pour le traitement de la maladie de wilson |
| US11419832B2 (en) * | 2017-12-04 | 2022-08-23 | Alexion Pharmaceuticals, Inc. | Bis-choline tetrathiomolybdate for treating Wilson Disease |
| US11739051B2 (en) | 2018-02-06 | 2023-08-29 | Alexion Pharmaceuticals, Inc. | Crystalline particles of bis-choline tetrathiomolybdate |
| WO2019158719A1 (fr) | 2018-02-15 | 2019-08-22 | Wilson Therapeutics Ab | Procédé de préparation de bis-choline tétrathiomolybdate |
| EP3911604A2 (fr) | 2019-01-14 | 2021-11-24 | Alexion Pharmaceuticals, Inc. | Procédés de préparation de tétrathiomolybdate d'ammonium |
| US11471497B1 (en) | 2019-03-13 | 2022-10-18 | David Gordon Bermudes | Copper chelation therapeutics |
| WO2022073850A1 (fr) | 2020-10-07 | 2022-04-14 | Cti Vascular Ag | Dispositifs bioactivables et procédés associés |
| US20240100088A1 (en) * | 2021-01-31 | 2024-03-28 | Alexion Pharmaceuticals, Inc. | Novel formulation for treating copper metabolism-associated diseases or disorders |
| WO2023086873A1 (fr) * | 2021-11-10 | 2023-05-19 | Reverspah Llc | Procédés et compositions de traitement du cancer |
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| CN120678065B (zh) * | 2024-03-13 | 2026-08-07 | 香港中文大学 | 一种肺癌移植瘤模型的构建方法 |
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| US2909541A (en) * | 1955-01-07 | 1959-10-20 | Inst Francais Du Petrole | Nitrogenous thiomolybdates |
| US3845770A (en) * | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
| US3916899A (en) * | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
| US4400282A (en) | 1980-12-05 | 1983-08-23 | Gulf Research & Development Company | Lubricating oils containing quaternary ammonium thiomolybdates |
| US4343746A (en) * | 1980-12-10 | 1982-08-10 | Gulf Research & Development Company | Quaternary ammonium thiomolybdates |
| US4430443A (en) * | 1982-07-20 | 1984-02-07 | Exxon Research And Engineering Co. | Supported carbon-containing molybdenum and tungsten sulfide catalysts, their preparation and use |
| GB8504253D0 (en) * | 1985-02-19 | 1985-03-20 | Ici Plc | Electrostatic spraying apparatus |
| DE3815221C2 (de) * | 1988-05-04 | 1995-06-29 | Gradinger F Hermes Pharma | Verwendung einer Retinol- und/oder Retinsäureester enthaltenden pharmazeutischen Zubereitung zur Inhalation zur Einwirkung auf die Schleimhäute des Tracheo-Bronchialtraktes einschließlich der Lungenalveolen |
| US5698155A (en) * | 1991-05-31 | 1997-12-16 | Gs Technologies, Inc. | Method for the manufacture of pharmaceutical cellulose capsules |
| US5639725A (en) * | 1994-04-26 | 1997-06-17 | Children's Hospital Medical Center Corp. | Angiostatin protein |
| EP0814861B1 (fr) * | 1995-03-14 | 2002-06-05 | Siemens Aktiengesellschaft | Atomiseur a ultrasons pourvu d'une unite amovible de dosage precis |
| IL117473A (en) * | 1995-03-14 | 2001-08-26 | Siemens Ag | Ultrasonic atomizer device with removable precision dosating unit |
| EP1027918B1 (fr) | 1997-10-17 | 2005-12-28 | Ebara Corporation | Procede et appareil de traitement de gaz d'echappement issus de la fabrication de semiconducteurs |
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| ATE228375T1 (de) * | 1998-09-04 | 2002-12-15 | Univ Michigan | THIOMOLYBDAT VERBUNDEN MIT MINDESTENS EINEM KOHLENHYDRAT, UND SEINE VERWENDUNG ZUR VORBEUGUNG UND BEHANDLUNG VON ERKRANKUNGEN, DIE DURCH EINE ANORMALE VASKULARISIERUNG GEKENNZEICHNET SIND, WIE Z.B. KREBS, ßFEUCHTEß MAKULADEGENERATION, RHEUMATOIDE ARTHRITIS |
| CN1262226A (zh) | 1999-12-03 | 2000-08-09 | 中国科学院兰州化学物理研究所 | 硫代钼酸盐及其制备方法和用途 |
| US6855340B2 (en) * | 2002-05-24 | 2005-02-15 | Regents Of The University Of Michigan | Copper lowering treatment of inflammatory and fibrotic diseases |
| GEP20074270B (en) * | 2002-07-23 | 2007-12-25 | Univ Michigan | Tetrapropylammonium tetrathiomolybdate and related compounds for anti-angiogenic therapies |
-
2003
- 2003-05-28 US US10/447,585 patent/US7189865B2/en not_active Expired - Lifetime
- 2003-07-22 JP JP2005505545A patent/JP2006506466A/ja active Pending
- 2003-07-22 EA EA200500250A patent/EA200500250A1/ru unknown
- 2003-07-22 DK DK03765973.7T patent/DK1556029T3/en active
- 2003-07-22 MX MXPA05000870A patent/MXPA05000870A/es active IP Right Grant
- 2003-07-22 SI SI200332340T patent/SI1556029T1/sl unknown
- 2003-07-22 AU AU2003256704A patent/AU2003256704A1/en not_active Abandoned
- 2003-07-22 PT PT37659737T patent/PT1556029E/pt unknown
- 2003-07-22 PL PL03374821A patent/PL374821A1/xx not_active Application Discontinuation
- 2003-07-22 KR KR1020057001310A patent/KR20050053596A/ko not_active Ceased
- 2003-07-22 WO PCT/US2003/023031 patent/WO2004009034A2/fr not_active Ceased
- 2003-07-22 ES ES03765973.7T patent/ES2448800T3/es not_active Expired - Lifetime
- 2003-07-22 CA CA002493127A patent/CA2493127A1/fr not_active Abandoned
- 2003-07-22 CN CNB038225557A patent/CN100531732C/zh not_active Expired - Lifetime
- 2003-07-22 HR HR20050174A patent/HRP20050174A2/hr not_active Application Discontinuation
- 2003-07-22 BR BR0312851-2A patent/BR0312851A/pt not_active IP Right Cessation
- 2003-07-22 EP EP03765973.7A patent/EP1556029B1/fr not_active Expired - Lifetime
-
2005
- 2005-01-23 IL IL16644805A patent/IL166448A0/xx unknown
- 2005-02-21 NO NO20050917A patent/NO20050917L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US7189865B2 (en) | 2007-03-13 |
| HRP20050174A2 (en) | 2005-10-31 |
| WO2004009034A2 (fr) | 2004-01-29 |
| WO2004009034A3 (fr) | 2004-09-10 |
| EP1556029A4 (fr) | 2008-06-25 |
| KR20050053596A (ko) | 2005-06-08 |
| US20040019087A1 (en) | 2004-01-29 |
| ES2448800T3 (es) | 2014-03-17 |
| PT1556029E (pt) | 2014-03-04 |
| CN1684678A (zh) | 2005-10-19 |
| EP1556029A2 (fr) | 2005-07-27 |
| JP2006506466A (ja) | 2006-02-23 |
| SI1556029T1 (sl) | 2014-06-30 |
| MXPA05000870A (es) | 2005-08-29 |
| EA200500250A1 (ru) | 2005-12-29 |
| PL374821A1 (en) | 2005-10-31 |
| CN100531732C (zh) | 2009-08-26 |
| BR0312851A (pt) | 2005-07-12 |
| AU2003256704A1 (en) | 2004-02-09 |
| CA2493127A1 (fr) | 2004-01-29 |
| DK1556029T3 (en) | 2014-03-10 |
| IL166448A0 (en) | 2006-01-15 |
| EP1556029B1 (fr) | 2013-11-27 |
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