NO20051223L - Oksadiazoler som modulatorer av metabotropisk glutamat reseptor-5. - Google Patents

Oksadiazoler som modulatorer av metabotropisk glutamat reseptor-5.

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Publication number
NO20051223L
NO20051223L NO20051223A NO20051223A NO20051223L NO 20051223 L NO20051223 L NO 20051223L NO 20051223 A NO20051223 A NO 20051223A NO 20051223 A NO20051223 A NO 20051223A NO 20051223 L NO20051223 L NO 20051223L
Authority
NO
Norway
Prior art keywords
oxadiazoles
modulators
glutamate receptor
metabotropic glutamate
compounds
Prior art date
Application number
NO20051223A
Other languages
English (en)
Inventor
Donald A Mcleod
Methvin Benjamin Isaac
Abdelmalik Slassi
Thomas M Stormann
David Wensbo
Tao Xin
Tomislav Stefanac
Jalaj Arora
Louise Edwards
Annika Kers
Johan Malmberg
Karin Oscarsson
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of NO20051223L publication Critical patent/NO20051223L/no

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    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
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    • C07D271/07—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
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    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
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    • C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
    • C07D271/113—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
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Abstract

Den foreliggende oppfinnelse vedrører nye forbindelser med formel (I), der P, Q, X1', X2, X3, X4,X5, R1, R2, R4, R5, M1, M2, m, n, o, p og q er som definert i et av kravene 1 - 12, en fremgangsmåte for deres fremstilling og nye mellomprodukter fremstilt deri, farmasøytiske blandinger som inneholder slike forbindelser og anvendelse av slike forbindelser i terapi.
NO20051223A 2002-08-09 2005-03-09 Oksadiazoler som modulatorer av metabotropisk glutamat reseptor-5. NO20051223L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40203902P 2002-08-09 2002-08-09
PCT/US2003/024912 WO2004014370A2 (en) 2002-08-09 2003-08-08 Oxadiazoles as modulators of metabotropic glutamate receptor-5

Publications (1)

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NO20051223L true NO20051223L (no) 2005-05-03

Family

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NO20051223A NO20051223L (no) 2002-08-09 2005-03-09 Oksadiazoler som modulatorer av metabotropisk glutamat reseptor-5.

Country Status (16)

Country Link
US (2) US20040132726A1 (no)
EP (1) EP1536790A2 (no)
JP (1) JP2006506340A (no)
KR (1) KR20050039846A (no)
CN (1) CN1691944A (no)
AR (1) AR041508A1 (no)
AU (1) AU2003268064A1 (no)
BR (1) BR0313266A (no)
CA (1) CA2495120A1 (no)
IL (1) IL166650A0 (no)
MX (1) MXPA05001592A (no)
NO (1) NO20051223L (no)
NZ (1) NZ538339A (no)
TW (2) TW200812986A (no)
WO (1) WO2004014370A2 (no)
ZA (1) ZA200501101B (no)

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