NO20051461L - lnhaleringssammensetning - Google Patents
lnhaleringssammensetningInfo
- Publication number
- NO20051461L NO20051461L NO20051461A NO20051461A NO20051461L NO 20051461 L NO20051461 L NO 20051461L NO 20051461 A NO20051461 A NO 20051461A NO 20051461 A NO20051461 A NO 20051461A NO 20051461 L NO20051461 L NO 20051461L
- Authority
- NO
- Norway
- Prior art keywords
- microns
- diameter
- less
- lactose particles
- mixture
- Prior art date
Links
- 239000000203 mixture Substances 0.000 abstract 5
- 239000002245 particle Substances 0.000 abstract 4
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 abstract 3
- 239000008101 lactose Substances 0.000 abstract 3
- 239000006185 dispersion Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940112141 dry powder inhaler Drugs 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Otolaryngology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Foreliggende oppfinnelse tilveiebringer en tørrpulverinhalereringssammensetning som innbefatter. medikamentpartikler og en blanding av laktosepartikler med en VMD på mellom ca. 70 og 120 mikron og en diameter på mindre enn 250 mikron, hvor blandingen er kjennetegnet ved at opp til 96 vekt-% av laktosepartiklene er mindre enn 150 mikron i diameter, og hvori opp til 25 vekt-% av laktosepartiklene er mindre enn 5 mikron i diameter. Sammensetningene tilveiebringer en mer nøyaktig, enhetlig og. konsistent dispersjon når den for eksempel anvendes med en multidose tørrpulveirnhalerer.Også beskrevet er fremgangsmåter for anvendelse av sammensetningene ifølge oppfinnelsen.The present invention provides a dry powder inhalation composition which includes. drug particles and a mixture of lactose particles with a VMD of between approx. 70 and 120 microns and a diameter of less than 250 microns, wherein the mixture is characterized in that up to 96% by weight of the lactose particles are less than 150 microns in diameter, and in which up to 25% by weight of the lactose particles are less than 5 microns. in diameter. The compositions provide a more accurate, uniform and. consistent dispersion when used, for example, with a multidose dry powder inhaler. Also described are methods of using the compositions of the invention.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0219513A GB0219513D0 (en) | 2002-08-21 | 2002-08-21 | Inhalation compositions including coarse carrier |
| PCT/US2003/026385 WO2004017914A2 (en) | 2002-08-21 | 2003-08-21 | Inhalation composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20051461L true NO20051461L (en) | 2005-05-20 |
Family
ID=9942746
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20051461A NO20051461L (en) | 2002-08-21 | 2005-03-18 | lnhaleringssammensetning |
Country Status (8)
| Country | Link |
|---|---|
| BR (1) | BRPI0313647A2 (en) |
| CA (1) | CA2499273C (en) |
| ES (1) | ES2371601T3 (en) |
| GB (1) | GB0219513D0 (en) |
| NO (1) | NO20051461L (en) |
| TN (1) | TNSN05047A1 (en) |
| WO (1) | WO2004017914A2 (en) |
| ZA (1) | ZA200502177B (en) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005102429A1 (en) | 2004-04-21 | 2005-11-03 | Innovata Biomed Limited | Inhaler |
| PL2708225T3 (en) | 2004-04-23 | 2019-07-31 | Cydex Pharmaceuticals, Inc. | DPI Formulation Containing Sulfoalkyl Ether Cyclodextrin |
| GB0409197D0 (en) | 2004-04-24 | 2004-05-26 | Innovata Biomed Ltd | Device |
| RU2007133547A (en) * | 2005-02-10 | 2009-03-20 | Глаксо Груп Лимитед (GB) | METHODS FOR PRODUCING LACTOSES USING PRELIMINARY SORTING METHODS AND PHARMACEUTICAL COMPOSITIONS PRODUCED FROM IT |
| US7629331B2 (en) | 2005-10-26 | 2009-12-08 | Cydex Pharmaceuticals, Inc. | Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof |
| GB0605723D0 (en) | 2006-03-23 | 2006-05-03 | 3M Innovative Properties Co | Powder filling processes |
| WO2008134817A1 (en) * | 2007-05-03 | 2008-11-13 | The University Of Sydney | Composite carriers for dry powder inhalation therapy |
| TR201105367A2 (en) * | 2011-06-02 | 2012-12-21 | Bi̇lgi̇ç Mahmut | A dry powder formulation with improved flow properties. |
| TR201205852A2 (en) * | 2011-06-02 | 2012-12-21 | Bi̇lgi̇ç Mahmut | Improved new dry powder formulation. |
| UA115989C2 (en) | 2012-07-05 | 2018-01-25 | Арвен Айлак Санайі Ве Тіджарет А.С. | Dry powder inhaler compositions comprising long acting muscorinic antagonists |
| NZ703866A (en) | 2012-07-19 | 2016-05-27 | Adamis Pharmaceuticals Corp | Powder feeding apparatus |
| JP6251667B2 (en) | 2014-06-03 | 2017-12-20 | アサヒカルピスウェルネス株式会社 | Tablet-type immediate release preparation and method for producing the same |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1283036T3 (en) * | 1998-11-13 | 2008-03-25 | Jagotec Ag | Dry powder for inhalation |
| DE69818872T2 (en) * | 1998-12-11 | 2004-05-19 | Pharmachemie B.V. | PHARMACEUTICAL PREPARATIONS FOR INHALATION OF AN OPIOID |
| PL200063B1 (en) | 2000-10-12 | 2008-12-31 | Boehringer Ingelheim Pharma | Novel tiotropium-containing inhalation powder |
| UA75375C2 (en) | 2000-10-12 | 2006-04-17 | Boehringer Ingelheim Pharma | Method for producing powdery preparations for inhaling |
-
2002
- 2002-08-21 GB GB0219513A patent/GB0219513D0/en not_active Ceased
-
2003
- 2003-08-21 ES ES03751884T patent/ES2371601T3/en not_active Expired - Lifetime
- 2003-08-21 BR BRPI0313647A patent/BRPI0313647A2/en active Search and Examination
- 2003-08-21 CA CA2499273A patent/CA2499273C/en not_active Expired - Fee Related
- 2003-08-21 WO PCT/US2003/026385 patent/WO2004017914A2/en not_active Ceased
-
2005
- 2005-02-18 TN TNP2005000047A patent/TNSN05047A1/en unknown
- 2005-03-15 ZA ZA200502177A patent/ZA200502177B/en unknown
- 2005-03-18 NO NO20051461A patent/NO20051461L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2004017914A3 (en) | 2004-04-29 |
| ES2371601T3 (en) | 2012-01-05 |
| GB0219513D0 (en) | 2002-10-02 |
| WO2004017914A2 (en) | 2004-03-04 |
| TNSN05047A1 (en) | 2007-05-14 |
| CA2499273C (en) | 2011-06-21 |
| ZA200502177B (en) | 2006-05-31 |
| WO2004017914A8 (en) | 2005-07-07 |
| BRPI0313647A2 (en) | 2019-02-19 |
| CA2499273A1 (en) | 2004-03-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application | ||
| RE | Reestablishment of rights (par. 72 patents act) | ||
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |