NO20052039L - Fremgangsmater og sammensetninger for behandling av lupus ved anvendelse av clorfarabine - Google Patents
Fremgangsmater og sammensetninger for behandling av lupus ved anvendelse av clorfarabineInfo
- Publication number
- NO20052039L NO20052039L NO20052039A NO20052039A NO20052039L NO 20052039 L NO20052039 L NO 20052039L NO 20052039 A NO20052039 A NO 20052039A NO 20052039 A NO20052039 A NO 20052039A NO 20052039 L NO20052039 L NO 20052039L
- Authority
- NO
- Norway
- Prior art keywords
- treatment
- methods
- chlorfarabine
- lupus
- compositions
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 206010025135 lupus erythematosus Diseases 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 208000023275 Autoimmune disease Diseases 0.000 abstract 2
- WDDPHFBMKLOVOX-AYQXTPAHSA-N clofarabine Chemical compound C1=NC=2C(N)=NC(Cl)=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1F WDDPHFBMKLOVOX-AYQXTPAHSA-N 0.000 abstract 2
- 229960000928 clofarabine Drugs 0.000 abstract 2
- 239000002207 metabolite Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41468502P | 2002-09-27 | 2002-09-27 | |
| PCT/US2003/030407 WO2004028463A2 (fr) | 2002-09-27 | 2003-09-25 | Techniques et compositions destinees au traitement du lupus utilisant la clofarabine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20052039L true NO20052039L (no) | 2005-06-23 |
Family
ID=32043398
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20052039A NO20052039L (no) | 2002-09-27 | 2005-04-26 | Fremgangsmater og sammensetninger for behandling av lupus ved anvendelse av clorfarabine |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20060135463A1 (fr) |
| EP (1) | EP1551386A4 (fr) |
| AU (1) | AU2003276987B2 (fr) |
| CA (1) | CA2500091A1 (fr) |
| NO (1) | NO20052039L (fr) |
| WO (1) | WO2004028463A2 (fr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060270707A1 (en) * | 2005-05-24 | 2006-11-30 | Zeldis Jerome B | Methods and compositions using 4-[(cyclopropanecarbonylamino)methyl]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione for the treatment or prevention of cutaneous lupus |
| EP2029664A4 (fr) | 2006-05-31 | 2015-09-09 | Dow Global Technologies Llc | Adjuvants pour emploi de l'énergie micro-onde dans le chauffage sélectif de systèmes polymères thermoplastiques |
| CN100591330C (zh) * | 2007-08-23 | 2010-02-24 | 江苏奥赛康药业有限公司 | 一种氯法拉滨冻干粉针剂及其制备方法 |
| KR100999798B1 (ko) * | 2010-02-11 | 2010-12-08 | 엘지이노텍 주식회사 | 반도체 발광소자 및 그 제조방법 |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3536809A (en) * | 1969-02-17 | 1970-10-27 | Alza Corp | Medication method |
| US3598123A (en) * | 1969-04-01 | 1971-08-10 | Alza Corp | Bandage for administering drugs |
| US3928319A (en) * | 1971-06-16 | 1975-12-23 | Syntex Inc | 4 -Fluoro nucleosides, novel intermediates and methods of preparing same |
| US3845770A (en) * | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
| US3916899A (en) * | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
| US4008719A (en) * | 1976-02-02 | 1977-02-22 | Alza Corporation | Osmotic system having laminar arrangement for programming delivery of active agent |
| DE2628202A1 (de) * | 1976-06-23 | 1977-12-29 | Max Planck Gesellschaft | Verfahren zur herstellung von 2'-substituierten-d-ribofuranosylpurinderivaten |
| US4210745A (en) * | 1978-01-04 | 1980-07-01 | The United States Of America As Represented By The Department Of Health, Education And Welfare | Procedure for the preparation of 9-β-D-arabinofuranosyl-2-fluoroadenine |
| US4188378A (en) * | 1978-01-04 | 1980-02-12 | The United States Of America As Represented By The Department Of Health, Education And Welfare | Anticancer and antiviral activity of 9-β-D-arabinofuranosyl-2-fluoroadenine |
| ZA791659B (en) * | 1978-04-17 | 1980-04-30 | Ici Ltd | Process and apparatus for spraying liquid |
| US4357324A (en) * | 1981-02-24 | 1982-11-02 | The United States Of America As Represented By The Department Of Health And Human Services | Prodrug derivatives of 9β-D-arabinofuranosyl-2-fluoroadenine |
| IE58110B1 (en) * | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
| GB8504253D0 (en) * | 1985-02-19 | 1985-03-20 | Ici Plc | Electrostatic spraying apparatus |
| US4751221A (en) * | 1985-10-18 | 1988-06-14 | Sloan-Kettering Institute For Cancer Research | 2-fluoro-arabinofuranosyl purine nucleosides |
| US5310732A (en) * | 1986-02-03 | 1994-05-10 | The Scripps Research Institute | 2-halo-2'-deoxyadenosines in the treatment of rheumatoid arthritis |
| US5106837A (en) * | 1988-03-16 | 1992-04-21 | The Scripps Research Institute | Adenosine derivatives with therapeutic activity |
| WO1989008658A1 (fr) * | 1988-03-16 | 1989-09-21 | Scripps Clinic And Research Foundation | Derives d'adenine substitues utiles en tant qu'agents therapeutiques |
| DE3815221C2 (de) * | 1988-05-04 | 1995-06-29 | Gradinger F Hermes Pharma | Verwendung einer Retinol- und/oder Retinsäureester enthaltenden pharmazeutischen Zubereitung zur Inhalation zur Einwirkung auf die Schleimhäute des Tracheo-Bronchialtraktes einschließlich der Lungenalveolen |
| US5073543A (en) * | 1988-07-21 | 1991-12-17 | G. D. Searle & Co. | Controlled release formulations of trophic factors in ganglioside-lipsome vehicle |
| IT1229203B (it) * | 1989-03-22 | 1991-07-25 | Bioresearch Spa | Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative. |
| US5034518A (en) * | 1989-05-23 | 1991-07-23 | Southern Research Institute | 2-fluoro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl) adenine nucleosides |
| US5384310A (en) * | 1989-05-23 | 1995-01-24 | Southern Research Institute | 2'-fluoro-2-haloarabinoadinosines and their pharmaceutical compositions |
| US5120548A (en) * | 1989-11-07 | 1992-06-09 | Merck & Co., Inc. | Swelling modulated polymeric drug delivery device |
| US5733566A (en) * | 1990-05-15 | 1998-03-31 | Alkermes Controlled Therapeutics Inc. Ii | Controlled release of antiparasitic agents in animals |
| GB9125660D0 (en) * | 1991-12-03 | 1992-01-29 | Smithkline Beecham Plc | Novel compound |
| US5580578A (en) * | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
| US5591767A (en) * | 1993-01-25 | 1997-01-07 | Pharmetrix Corporation | Liquid reservoir transdermal patch for the administration of ketorolac |
| AU7470794A (en) * | 1994-05-26 | 1995-12-21 | Scripps Research Institute, The | 2-halo-2'-deoxyadenosine treatement for inflammatory bowel disease |
| IT1270594B (it) * | 1994-07-07 | 1997-05-07 | Recordati Chem Pharm | Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida |
| US5970974A (en) * | 1995-03-14 | 1999-10-26 | Siemens Aktiengesellschaft | Dosating unit for an ultrasonic atomizer device |
| EP0814860B1 (fr) * | 1995-03-14 | 1999-11-03 | Siemens Aktiengesellschaft | Atomiseur a ultrasons pourvu d'une unite de dosage precis amovible |
| US5954047A (en) * | 1997-10-17 | 1999-09-21 | Systemic Pulmonary Development, Ltd. | Methods and apparatus for delivering aerosolized medication |
| AU2002250236A1 (en) * | 2001-03-02 | 2002-09-19 | Medimmune, Inc. | Cd2 antagonists for treatment of autoimmune or inflammatory disease |
| CA2439852A1 (fr) * | 2001-03-02 | 2002-09-12 | Christine Dingivan | Prevention ou traitement de troubles inflammatoires ou auto-immuns par l'administration d'antagonistes de l'integrine alphav beta3 |
| WO2004029025A2 (fr) * | 2002-09-27 | 2004-04-08 | Bioenvision, Inc. | Methodes et compositions pour traiter des troubles auto-immunes a l'aide de clofarabine |
-
2003
- 2003-09-25 EP EP03798756A patent/EP1551386A4/fr not_active Withdrawn
- 2003-09-25 US US10/529,520 patent/US20060135463A1/en not_active Abandoned
- 2003-09-25 AU AU2003276987A patent/AU2003276987B2/en not_active Ceased
- 2003-09-25 CA CA002500091A patent/CA2500091A1/fr not_active Abandoned
- 2003-09-25 WO PCT/US2003/030407 patent/WO2004028463A2/fr not_active Ceased
-
2005
- 2005-04-26 NO NO20052039A patent/NO20052039L/no not_active Application Discontinuation
-
2009
- 2009-02-27 US US12/394,832 patent/US20090297478A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1551386A4 (fr) | 2009-03-25 |
| WO2004028463A2 (fr) | 2004-04-08 |
| US20090297478A1 (en) | 2009-12-03 |
| US20060135463A1 (en) | 2006-06-22 |
| CA2500091A1 (fr) | 2004-04-08 |
| EP1551386A2 (fr) | 2005-07-13 |
| AU2003276987A1 (en) | 2004-04-19 |
| AU2003276987B2 (en) | 2009-07-30 |
| WO2004028463A3 (fr) | 2004-07-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |