NO20052481L - Hoy ekspresjons locusvektor basert pa ferritin tung kjede genlocus. - Google Patents

Hoy ekspresjons locusvektor basert pa ferritin tung kjede genlocus.

Info

Publication number
NO20052481L
NO20052481L NO20052481A NO20052481A NO20052481L NO 20052481 L NO20052481 L NO 20052481L NO 20052481 A NO20052481 A NO 20052481A NO 20052481 A NO20052481 A NO 20052481A NO 20052481 L NO20052481 L NO 20052481L
Authority
NO
Norway
Prior art keywords
heavy chain
locus
high expression
ferritin
vector based
Prior art date
Application number
NO20052481A
Other languages
English (en)
Other versions
NO20052481D0 (no
Inventor
Holly Prentice
Original Assignee
Biogen Idec Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Idec Inc filed Critical Biogen Idec Inc
Publication of NO20052481D0 publication Critical patent/NO20052481D0/no
Publication of NO20052481L publication Critical patent/NO20052481L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
    • C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2800/00—Nucleic acids vectors
    • C12N2800/10—Plasmid DNA
    • C12N2800/106—Plasmid DNA for vertebrates
    • C12N2800/107—Plasmid DNA for vertebrates for mammalian
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/80—Vectors comprising a special translation-regulating system from vertebrates
    • C12N2840/85—Vectors comprising a special translation-regulating system from vertebrates mammalian

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

"Locus" vektorer for høyekspresjon, delvis basert på ferritinets tunge kjedes locus er fremlagt. Vektorene inkluderer distale 5'flankerende sekvenser og/eller proximale 5' regulatoriske sekvenser avledet fra ferritinets tunge kjedes locus. Vektorene inneholder seter for innsetting av heterologe sekvenser og proximale 3'regulatoriske og distale 3'flankerende sekvenser. De proximale 3' regulatoriske og de distale 3'flankerende sekvensene kan valgfritt være avledet fra ferritinets tunge kjedes locus i celler transformert med vektorene, og metoder for å produsere heterologe proteiner som vektoren koder for er også fremlagt.
NO20052481A 2002-10-24 2005-05-23 Hoy ekspresjons locusvektor basert pa ferritin tung kjede genlocus. NO20052481L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42125202P 2002-10-24 2002-10-24
PCT/US2003/033433 WO2004037982A2 (en) 2002-10-24 2003-10-22 High expression locus vector based on ferritin heavy chain gene locus

Publications (2)

Publication Number Publication Date
NO20052481D0 NO20052481D0 (no) 2005-05-23
NO20052481L true NO20052481L (no) 2005-07-25

Family

ID=32176688

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20052481A NO20052481L (no) 2002-10-24 2005-05-23 Hoy ekspresjons locusvektor basert pa ferritin tung kjede genlocus.

Country Status (18)

Country Link
US (1) US20070031920A1 (no)
EP (1) EP1558725A4 (no)
JP (1) JP2006503583A (no)
KR (1) KR20050084867A (no)
CN (1) CN1732258A (no)
AU (1) AU2003286577B2 (no)
BR (1) BR0315650A (no)
CA (1) CA2503437A1 (no)
EA (1) EA008222B1 (no)
GE (1) GEP20084388B (no)
IS (1) IS7797A (no)
MX (1) MXPA05004163A (no)
NO (1) NO20052481L (no)
NZ (1) NZ539423A (no)
PL (1) PL376561A1 (no)
RS (1) RS20050367A (no)
WO (1) WO2004037982A2 (no)
ZA (1) ZA200502986B (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI3495482T1 (sl) * 2014-01-21 2021-03-31 Synplogen Co., Ltd. Postopek priprave sestavka enote DNK in postopek izdelave konkatemera DNK
CN116589553A (zh) * 2023-03-27 2023-08-15 集美大学 大黄鱼铁蛋白重链抗菌抗虫片段LcFet-H51及其应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4740461A (en) * 1983-12-27 1988-04-26 Genetics Institute, Inc. Vectors and methods for transformation of eucaryotic cells
ATE243754T1 (de) * 1987-05-21 2003-07-15 Micromet Ag Multifunktionelle proteine mit vorbestimmter zielsetzung
US5672510A (en) * 1990-01-19 1997-09-30 Genetic Therapy, Inc. Retroviral vectors
US6225290B1 (en) * 1996-09-19 2001-05-01 The Regents Of The University Of California Systemic gene therapy by intestinal cell transformation
DE10006886A1 (de) * 2000-02-16 2001-08-23 Hepavec Ag Fuer Gentherapie Nichthumaner helferabhängiger Virusvektor
AU2002310275B2 (en) * 2001-05-30 2006-08-31 Glaxo Group Limited Chromosome-based platforms

Also Published As

Publication number Publication date
NZ539423A (en) 2006-12-22
EA008222B1 (ru) 2007-04-27
CA2503437A1 (en) 2004-05-06
JP2006503583A (ja) 2006-02-02
NO20052481D0 (no) 2005-05-23
AU2003286577A1 (en) 2004-05-13
EP1558725A2 (en) 2005-08-03
EA200500700A1 (ru) 2005-10-27
RS20050367A (sr) 2007-08-03
KR20050084867A (ko) 2005-08-29
BR0315650A (pt) 2005-09-20
WO2004037982A2 (en) 2004-05-06
WO2004037982A3 (en) 2004-09-30
CN1732258A (zh) 2006-02-08
US20070031920A1 (en) 2007-02-08
ZA200502986B (en) 2005-10-20
EP1558725A4 (en) 2006-11-08
MXPA05004163A (es) 2005-10-05
GEP20084388B (en) 2008-06-10
AU2003286577B2 (en) 2008-09-04
IS7797A (is) 2005-04-11
PL376561A1 (pl) 2006-01-09

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