NO20052574L - Fremgangsmate til a fremstille en farmasoytisk aktiv forbindelse og til a fremstille dens mellomprodukt - Google Patents

Fremgangsmate til a fremstille en farmasoytisk aktiv forbindelse og til a fremstille dens mellomprodukt

Info

Publication number: NO20052574L
Authority: NO; Norway
Prior art keywords: preparing; active compound; pharmaceutically active; dichlorophenyl; formula
Prior art date: 2002-10-31

Application number

NO20052574A

Other languages

English (en)

Norwegian (no)

Inventor

Pere Dalmases Barjoan

Jordi Bessa Bellmunt

Original Assignee

Vita Cientifica Srl

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-10-31

Filing date

2005-05-27

Publication date

2005-05-27

2005-05-27 Application filed by Vita Cientifica Srl filed Critical Vita Cientifica Srl

2005-05-27 Publication of NO20052574L publication Critical patent/NO20052574L/no

Links

238000004519 manufacturing process Methods 0.000 title abstract 2
150000001875 compounds Chemical class 0.000 title 1
-1 2,3-dichlorophenyl-2-aminoguanidine acetonitrile Chemical compound 0.000 abstract 2
AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical compound CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 abstract 2
FIBBFBXFASKAON-UHFFFAOYSA-N 2,3-dichlorobenzoyl cyanide Chemical compound ClC1=CC=CC(C(=O)C#N)=C1Cl FIBBFBXFASKAON-UHFFFAOYSA-N 0.000 abstract 1
BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 abstract 1
239000012736 aqueous medium Substances 0.000 abstract 1
229940098779 methanesulfonic acid Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
- C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
- C07C281/18—Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4966—Triazines or their condensed derivatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D253/075—Two hetero atoms, in positions 3 and 5

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Birds (AREA)
Epidemiology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

NO20052574A 2002-10-31 2005-05-27 Fremgangsmate til a fremstille en farmasoytisk aktiv forbindelse og til a fremstille dens mellomprodukt NO20052574L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
ES200202502A ES2209639B1 (es)	2002-10-31	2002-10-31	Procedimiento para la obtencion de un compuesto farmaceuticamente activo y obtencion de su intermedio.
PCT/IB2003/004763 WO2004039767A1 (en)	2002-10-31	2003-10-27	Process for preparing a pharmaceutically active compound and for preparing its intermediate

Publications (1)

Publication Number	Publication Date
NO20052574L true NO20052574L (no)	2005-05-27

Family

ID=32187427

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20052574A NO20052574L (no)	2002-10-31	2005-05-27	Fremgangsmate til a fremstille en farmasoytisk aktiv forbindelse og til a fremstille dens mellomprodukt

Country Status (8)

Country	Link
US (1)	US7179913B2 (is)
EP (1)	EP1556341A1 (is)
KR (1)	KR100753354B1 (is)
AU (1)	AU2003272019A1 (is)
ES (1)	ES2209639B1 (is)
IS (1)	IS7846A (is)
NO (1)	NO20052574L (is)
WO (1)	WO2004039767A1 (is)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2007069265A1 (en) *	2005-12-12	2007-06-21	Unichem Laboratories Limited	A novel process for the synthesis of lamotrigine and its intermediate
US20120142919A1 (en) *	2006-08-02	2012-06-07	Medichem, S.A.	Method for synthesizing lamotrigine
WO2009069073A1 (en) *	2007-11-28	2009-06-04	Alembic Limited	An improved process for the preparation of lamotrigine

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0021121B1 (en)	1979-06-01	1983-05-11	The Wellcome Foundation Limited	1,2,4-triazine derivatives, process for preparing such compounds and pharmaceutical compositions containing them
GB8613183D0 (en)	1986-05-30	1986-07-02	Wellcome Found	Triazine salt
GB9812413D0 (en)	1998-06-10	1998-08-05	Glaxo Group Ltd	Compound and its use
CZ20011949A3 (cs)	1998-12-14	2001-09-12	Torrent Pharmacauticals Ltd	Zlepšený způsob výroby 3,5-diamino-6-(2,3-dichlorfenyl)-1,2,4-triazinu
WO2001049669A1 (en) *	2000-01-03	2001-07-12	Rpg Life Sciences Limited	A process for the preparation of 6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine, commonly known as lamotrigine
IL134730A (en) *	2000-02-25	2003-10-31	Chemagis Ltd	Process for preparing substituted benzoyl cyanide amidinohydrazones
CA2366521C (en)	2001-12-24	2007-03-06	Brantford Chemicals Inc.	A new and efficient process for the preparation of lamotrigine and related 3,5-diamino-6-substituted-1,2,4-triazines
HU225667B1 (en) *	2002-09-20	2007-05-29	Richter Gedeon Nyrt	Method for producing high-purity 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine

2002
- 2002-10-31 ES ES200202502A patent/ES2209639B1/es not_active Expired - Fee Related
2003
- 2003-10-27 AU AU2003272019A patent/AU2003272019A1/en not_active Abandoned
- 2003-10-27 EP EP03753860A patent/EP1556341A1/en not_active Withdrawn
- 2003-10-27 US US10/532,397 patent/US7179913B2/en not_active Expired - Fee Related
- 2003-10-27 WO PCT/IB2003/004763 patent/WO2004039767A1/en not_active Ceased
- 2003-10-27 KR KR1020057007654A patent/KR100753354B1/ko not_active Expired - Fee Related
2005
- 2005-05-13 IS IS7846A patent/IS7846A/is unknown
- 2005-05-27 NO NO20052574A patent/NO20052574L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
WO2004039767A1 (en)	2004-05-13
EP1556341A1 (en)	2005-07-27
ES2209639A1 (es)	2004-06-16
KR100753354B1 (ko)	2007-08-30
AU2003272019A1 (en)	2004-05-25
ES2209639B1 (es)	2005-08-01
US20060052625A1 (en)	2006-03-09
US7179913B2 (en)	2007-02-20
IS7846A (is)	2005-05-13
KR20050083883A (ko)	2005-08-26

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Legal Events

Date	Code	Title	Description
2009-05-25	FC2A	Withdrawal, rejection or dismissal of laid open patent application