NO20053139L - Sinomenin og sinomeninforbindelser, syntese og anvendelse. - Google Patents

Sinomenin og sinomeninforbindelser, syntese og anvendelse.

Info

Publication number: NO20053139L
Authority: NO; Norway
Prior art keywords: sinomenin; compounds; synthesis; recre; eres
Prior art date: 2002-11-28

Application number

NO20053139A

Other languages

English (en)

Norwegian (no)

Inventor

Pierre Renard

Pierre Lestage

Daniel-Henri Caignard

Xi-Can Tang

Guo-Wei Qin

Rui Wang

Tian-Xi Zhou

Original Assignee

Servier Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-11-28

Filing date

2005-06-27

Publication date

2005-06-27

2005-06-27 Application filed by Servier Lab filed Critical Servier Lab

2005-06-27 Publication of NO20053139L publication Critical patent/NO20053139L/no

Links

INYYVPJSBIVGPH-UHFFFAOYSA-N 14-episinomenine Natural products C1CN(C)C2CC3=CC=C(OC)C(O)=C3C31C2C=C(OC)C(=O)C3 INYYVPJSBIVGPH-UHFFFAOYSA-N 0.000 title abstract 3
150000001875 compounds Chemical class 0.000 title abstract 3
230000015572 biosynthetic process Effects 0.000 title 1
238000003786 synthesis reaction Methods 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/28—Morphinans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Other In-Based Heterocyclic Compounds (AREA)

NO20053139A 2002-11-28 2005-06-27 Sinomenin og sinomeninforbindelser, syntese og anvendelse. NO20053139L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
CNB021538190A CN1328280C (zh)	2002-11-28	2002-11-28	汉防己碱和汉防己碱化合物,合成和应用
PCT/EP2003/014841 WO2004048340A1 (fr)	2002-11-28	2003-11-26	Sinomenine et composes de sinomenine, procede de synthese associe et utilisation associee

Publications (1)

Publication Number	Publication Date
NO20053139L true NO20053139L (no)	2005-06-27

Family

ID=32331921

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20053139A NO20053139L (no)	2002-11-28	2005-06-27	Sinomenin og sinomeninforbindelser, syntese og anvendelse.

Country Status (15)

Country	Link
US (1)	US20060009480A1 (fr)
EP (1)	EP1565444A1 (fr)
JP (1)	JP2006509755A (fr)
KR (1)	KR100706462B1 (fr)
CN (2)	CN1328280C (fr)
AU (1)	AU2003290119A1 (fr)
BR (1)	BR0316609A (fr)
CA (1)	CA2507067A1 (fr)
EA (1)	EA200500862A1 (fr)
MA (1)	MA27573A1 (fr)
MX (1)	MXPA05005687A (fr)
NO (1)	NO20053139L (fr)
PL (1)	PL377695A1 (fr)
WO (1)	WO2004048340A1 (fr)
ZA (1)	ZA200504055B (fr)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN1298720C (zh) *	2005-03-18	2007-02-07	中国科学院上海有机化学研究所	C环连接有五元杂环的青藤碱衍生物和合成方法
CN1298718C (zh) *	2005-03-18	2007-02-07	中国科学院上海有机化学研究所	C环连接有吡嗪环的青藤碱衍生物、合成方法及其用途
CN100455571C (zh) *	2005-12-09	2009-01-28	湖南正清制药集团股份有限公司	青藤碱盐化合物及其制备方法
CN100408578C (zh) *	2006-03-15	2008-08-06	南京大学	一类17-酰基青藤碱衍生物及其制备方法
JP2009519960A (ja)	2005-12-15	2009-05-21	ナチュアメッドグループコーポレーション	シノメニン派生物の調合と使用
CN101578101B (zh) *	2005-12-15	2012-05-23	自然医学公司	青藤碱衍生物的制备和应用
CN101092397B (zh) *	2006-06-19	2011-01-19	湖南正清制药集团股份有限公司	一种青藤碱结构改造化合物及其制备方法
CN1876634A (zh) *	2006-06-19	2006-12-13	湖南正清制药集团股份有限公司	一种青藤碱结构改造化合物及其制备方法
US20070290378A1 (en) *	2006-06-20	2007-12-20	International Business Machines Corporation	Novel reworkable underfills for ceramic mcm c4 protection
CN100396686C (zh) *	2006-08-03	2008-06-25	西安皓天生物工程技术有限责任公司	一种汉防己甲素和汉防己乙素的制备方法
CN102093373A (zh) *	2007-06-19	2011-06-15	湖南正清制药集团股份有限公司	一种青藤碱结构改造化合物及其制备方法
NZ611651A (en) *	2007-12-17	2014-11-28	Mallinckrodt Llc	Sinomenine derivatives and processes for their synthesis
WO2010096790A1 (fr) *	2009-02-23	2010-08-26	Mallinckrodt Inc.	(+)-morphinane n-oxydes et procédés de préparation
EP2340832A1 (fr) *	2009-12-23	2011-07-06	Universität Innsbruck	Composés de morphine-6-one pour le traitement ou la prévention des maladies neurodégénératives
CN101798285B (zh) *	2010-02-10	2012-05-23	中国科学院上海有机化学研究所	一种青藤碱衍生物、合成方法及其用途
CN101899004A (zh) *	2010-06-24	2010-12-01	江苏大学	青藤碱衍生物、制备方法及其医药用途
CN101948430A (zh) *	2010-09-01	2011-01-19	南京大学	青藤碱衍生物及其制备方法和应用
CN102532024B (zh) *	2011-12-28	2016-08-03	赵爱国	青藤碱衍生物
CN104306954B (zh) *	2014-09-25	2016-08-24	中山大学	Wry三肽在制备治疗阿尔茨海默症药物中的用途
CN104274817B (zh) *	2014-09-25	2016-06-15	中山大学	Wrw三肽在制备治疗阿尔茨海默症药物中的用途
CN104258372B (zh) *	2014-09-25	2017-01-25	中山大学	Rgd三肽在制备治疗阿尔茨海默症药物中的用途
CN104258371B (zh) *	2014-09-25	2016-06-15	中山大学	Www三肽在制备治疗阿尔茨海默症药物中的用途
JP7321490B2 (ja)	2016-02-10	2023-08-07	グレーピラージェームズ	強化された膨張可能な音波減衰システム
CN107648179A (zh) *	2017-09-21	2018-02-02	浙江中医药大学	一种治疗类风湿性关节炎的新型皮肤给药制剂及其制备方法
CN108704640B (zh) *	2018-06-13	2021-03-30	绍兴市梓昂新材料有限公司	一种多孔氧化铂催化剂的制备方法
CN110433132B (zh) *	2019-08-19	2023-06-30	中国人民解放军军事科学院军事医学研究院	治疗创伤后应激障碍的粉防己碱鼻用制剂
CN113880764B (zh) *	2020-07-01	2023-04-18	北京师范大学	青藤碱衍生物及其制备方法与应用
CN114831990A (zh) *	2022-03-22	2022-08-02	台州恩泽医疗中心(集团)	青藤碱在制备治疗帕金森病药物组合物中的应用
CN115260098B (zh) *	2022-06-09	2024-06-04	澳门科技大学	Abcb5抑制剂在制备多耐药性类风湿性关节炎治疗药物中的应用
CN117281801B (zh) *	2023-09-15	2025-09-02	云南贝泰妮生物科技集团股份有限公司	α-酮丁酸盐在制备预防和或治疗皮肤光老化护肤品和药物中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4912114A (en) *	1988-03-18	1990-03-27	Sandoz Ltd.	Morphinan derivatives
EP0661283B1 (fr) *	1993-07-19	1998-10-21	Toray Industries, Inc.	Agent de protection de cellules cerebrales
JP2002503693A (ja) *	1998-02-20	2002-02-05	アブマックス，インコーポレイティド	エピモルフィン型化合物及びその使用

2002
- 2002-11-28 CN CNB021538190A patent/CN1328280C/zh not_active Expired - Fee Related
2003
- 2003-11-26 PL PL377695A patent/PL377695A1/pl unknown
- 2003-11-26 EA EA200500862A patent/EA200500862A1/ru unknown
- 2003-11-26 CA CA002507067A patent/CA2507067A1/fr not_active Abandoned
- 2003-11-26 WO PCT/EP2003/014841 patent/WO2004048340A1/fr not_active Ceased
- 2003-11-26 AU AU2003290119A patent/AU2003290119A1/en not_active Abandoned
- 2003-11-26 KR KR1020057009584A patent/KR100706462B1/ko not_active Expired - Fee Related
- 2003-11-26 JP JP2004554526A patent/JP2006509755A/ja active Pending
- 2003-11-26 EP EP03782481A patent/EP1565444A1/fr not_active Withdrawn
- 2003-11-26 CN CNA200380104606XA patent/CN1720232A/zh active Pending
- 2003-11-26 BR BR0316609-0A patent/BR0316609A/pt not_active IP Right Cessation
- 2003-11-26 MX MXPA05005687A patent/MXPA05005687A/es not_active Application Discontinuation
- 2003-11-26 US US10/536,613 patent/US20060009480A1/en not_active Abandoned
2005
- 2005-05-19 ZA ZA200504055A patent/ZA200504055B/en unknown
- 2005-06-27 NO NO20053139A patent/NO20053139L/no not_active Application Discontinuation
- 2005-06-27 MA MA28362A patent/MA27573A1/fr unknown

Also Published As

Publication number	Publication date
JP2006509755A (ja)	2006-03-23
US20060009480A1 (en)	2006-01-12
MA27573A1 (fr)	2005-10-03
WO2004048340A8 (fr)	2005-07-07
KR100706462B1 (ko)	2007-04-10
AU2003290119A1 (en)	2004-06-18
EP1565444A1 (fr)	2005-08-24
EA200500862A1 (ru)	2005-12-29
ZA200504055B (en)	2006-08-30
MXPA05005687A (es)	2005-08-16
KR20050071712A (ko)	2005-07-07
PL377695A1 (pl)	2006-02-06
CN1328280C (zh)	2007-07-25
BR0316609A (pt)	2005-10-11
CN1720232A (zh)	2006-01-11
CA2507067A1 (fr)	2004-06-10
WO2004048340A1 (fr)	2004-06-10
CN1504469A (zh)	2004-06-16

Legal Events

Date	Code	Title	Description
2008-06-30	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
SE9904652D0 (sv)	1999-12-17	Novel Compounds
BR0307833A (pt)	2004-12-07	Sìntese controlada de ziprasidona e suas composições
CY1111867T1 (el)	2015-11-04	Ενωση ενεργοποιησης ppar και φαρμακευτικη συνθεση που περιεχει αυτη
DE60211223D1 (de)	2006-06-08	Piperidinderivate als Kalium-Kanal Blockers
BR0010690A (pt)	2002-02-05	Composições de poliuretano-uréia contendo silìcio
IS6658A (is)	2002-12-17	Ný efnasambönd
GB0031103D0 (en)	2001-01-31	Chemical compounds
DK1613304T3 (da)	2008-01-21	DPP-IV-inhibitorer
NO20050065L (no)	2005-04-22	Kjemiske forbindelser
SE0200920D0 (sv)	2002-03-25	Novel compounds
DK1506203T3 (da)	2007-05-14	Syntese af epothiloner, mellemprodukter deraf, analoger deraf og anvendelser deraf
SE0300119D0 (sv)	2003-01-17	Novel compounds
BR0316609A (pt)	2005-10-11	Sinomenina e compostos de sinomenina, sìntese e uso
MXPA04009476A (es)	2005-01-25	Compuestos de (tiazol-4,2-disustituidos-5-il)amina como inhibidores de la pde7.
TWI319399B (en)	2010-01-11	Biguanide and dihydrotriazine derivatives
SE0101038D0 (sv)	2001-03-23	Novel compounds
NO20054787L (no)	2005-11-14	Indenderivater som farmasotiske midler
DE60117594D1 (de)	2006-04-27	3-oxadiazol-5-yl-1-aminoalkyl-1h-indolderivate
IL173810A0 (en)	2006-07-05	Imidazopyridine derivatives and pharmaceutical compositions containing the same
NO20062629L (no)	2006-09-06	Oksazolderivater av tetrackliner
TR200401052T4 (tr)	2004-11-22	Yeni bileşikler
MXPA06003345A (es)	2006-06-08	Derivados de aminopiridina como inhibidores de la no-sintasa inducible.
MXPA04009421A (es)	2005-01-25	Compuestos de tiazol-2-ilimina como inhibidores de la pde-7.
NO20044466L (no)	2004-12-21	Plasma-karboksypeptidase B-inhibitorer
NO20062710L (no)	2006-06-30	1-N-fenyl-amino-1H-imidazolderivater og farmasoytiske sammensetninger