NO20055848L - Nye spacer-enheter for poly(etylenglykol)-modifiserte peptidbaserte forbindelser - Google Patents
Nye spacer-enheter for poly(etylenglykol)-modifiserte peptidbaserte forbindelserInfo
- Publication number
- NO20055848L NO20055848L NO20055848A NO20055848A NO20055848L NO 20055848 L NO20055848 L NO 20055848L NO 20055848 A NO20055848 A NO 20055848A NO 20055848 A NO20055848 A NO 20055848A NO 20055848 L NO20055848 L NO 20055848L
- Authority
- NO
- Norway
- Prior art keywords
- unit
- poly
- ethylene glycol
- based compounds
- modified peptide
- Prior art date
Links
- 125000006850 spacer group Chemical group 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 229920001223 polyethylene glycol Polymers 0.000 title abstract 2
- 108091005601 modified peptides Proteins 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 229920003169 water-soluble polymer Polymers 0.000 abstract 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical group OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/524—Thrombopoietin, i.e. C-MPL ligand
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/505—Erythropoietin [EPO]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Diabetes (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Polyamides (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US46999603P | 2003-05-12 | 2003-05-12 | |
| PCT/US2004/014887 WO2004100997A2 (en) | 2003-05-12 | 2004-05-12 | Spacer moiety for poly(ethylene glycol) -modified peptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20055848L true NO20055848L (no) | 2006-02-13 |
Family
ID=33452348
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20055848A NO20055848L (no) | 2003-05-12 | 2005-12-09 | Nye spacer-enheter for poly(etylenglykol)-modifiserte peptidbaserte forbindelser |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US7919118B2 (is) |
| EP (2) | EP2204193A3 (is) |
| JP (2) | JP2007500218A (is) |
| KR (1) | KR101160611B1 (is) |
| CN (1) | CN1849141A (is) |
| AU (1) | AU2004238364A1 (is) |
| BR (1) | BRPI0411166A (is) |
| CA (1) | CA2525399A1 (is) |
| EA (1) | EA010015B1 (is) |
| IL (1) | IL171885A0 (is) |
| IS (1) | IS8168A (is) |
| MX (1) | MXPA05012314A (is) |
| NO (1) | NO20055848L (is) |
| NZ (2) | NZ563042A (is) |
| WO (1) | WO2004100997A2 (is) |
| ZA (1) | ZA200509970B (is) |
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| US7919118B2 (en) | 2003-05-12 | 2011-04-05 | Affymax, Inc. | Spacer moiety for poly (ethylene glycol) modified peptide based compounds |
| AU2004238868B2 (en) | 2003-05-12 | 2010-01-21 | Affymax, Inc. | Peptides that bind to the erythropoietin receptor |
| CN1820024B (zh) * | 2003-05-12 | 2011-06-22 | 阿费麦克斯公司 | 新的聚(乙二醇)修饰的化合物及其用途 |
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| FR2857875A1 (fr) * | 2003-07-25 | 2005-01-28 | Univ Reims Champagne Ardenne | Vaccin therapeutique cible contre la p-glycoproteine 170 pour inhiber la resistance multidrogues dans le traitement des cancers |
| US20080026995A1 (en) * | 2003-07-25 | 2008-01-31 | Ac Immune Sa | Therapeutic vaccine targeted against p-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers |
| US7807171B2 (en) | 2003-07-25 | 2010-10-05 | Ac Immune Sa | Therapeutic vaccine targeted against P-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers |
| US20070275007A1 (en) * | 2003-11-05 | 2007-11-29 | The Government Of The United States Of America, Represented By The Secretary Of Health And Human S | Carbohydrate Antigen-Nanoparticle Conjugates and Uses Thereof as Antimetastatic Agents in Treating Cancer |
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| US7550433B2 (en) | 2005-06-03 | 2009-06-23 | Affymax, Inc. | Erythropoietin receptor peptide formulations and uses |
| CN101528263B (zh) | 2006-06-30 | 2013-01-23 | Sku资产管理有限公司 | 用于癌症的先天性免疫方法的缀合物 |
| WO2008100288A2 (en) * | 2006-09-15 | 2008-08-21 | The Burnham Institute | High affinity ephb receptor binding compounds and methods of use thereof |
| EP2118127A4 (en) * | 2007-01-31 | 2010-12-01 | Affymax Inc | NICKET-BASED LINKER FOR BONDING MODIFYING GROUPS OF POLYPEPTIDES AND OTHER MACROMOLECULES |
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| US20090131317A1 (en) * | 2007-06-22 | 2009-05-21 | Affymax, Inc. | Compounds and peptides that bind the trail receptor |
| CN101143894A (zh) * | 2007-06-22 | 2008-03-19 | 中国药科大学 | 高效抑制血管生成多肽及其物理化学修饰方法和应用 |
| EP2018835B1 (de) | 2007-07-09 | 2014-03-05 | Augustinus Bader | Wirkstoff abgebendes Pflaster |
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| JP5563475B2 (ja) * | 2007-12-20 | 2014-07-30 | メルク セローノ ソシエテ アノニム | Pegインターフェロン−ベータ製剤 |
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| WO2012020124A1 (en) | 2010-08-12 | 2012-02-16 | Ac Immune S.A. | Vaccine engineering |
| JP6027011B2 (ja) | 2010-10-26 | 2016-11-16 | エーシー イミューン ソシエテ アノニム | 疎水性部分によって修飾されたペプチドを含むリポソームベースの構築物 |
| US9463255B1 (en) * | 2011-09-29 | 2016-10-11 | Stc.Unm | Radiolabeled alpha-melanocyte stimulating hormone hybrid peptide for melanoma targeting |
| JP6822839B2 (ja) | 2013-09-13 | 2021-01-27 | ザ・スクリップス・リサーチ・インスティテュート | 修飾された治療剤、及びその組成物 |
| KR102455171B1 (ko) | 2013-12-18 | 2022-10-14 | 더 스크립스 리서치 인스티튜트 | 변형된 치료제, 스테이플드 펩티드 지질 접합체, 및 이의 조성물 |
| WO2016205488A1 (en) * | 2015-06-17 | 2016-12-22 | The California Institute For Biomedical Research | Modified therapeutic agents and compositions thereof |
| GB201609083D0 (en) | 2016-05-24 | 2016-07-06 | Syntab Therapeutics Gmbh | Synthetic compound |
| KR102142978B1 (ko) * | 2017-12-18 | 2020-08-11 | 경희대학교 산학협력단 | 신규 페길화 서브스턴스 p |
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| MX2022006861A (es) | 2019-12-04 | 2022-07-11 | Scripps Research Inst | Agonistas del receptor glp2 y metodos de uso. |
| KR20240032010A (ko) | 2021-06-09 | 2024-03-08 | 더 스크립스 리서치 인스티튜트 | 장기 지속형 이중 gip/glp-1 펩타이드 접합체 및 사용 방법 |
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-
2004
- 2004-05-12 US US10/555,860 patent/US7919118B2/en not_active Expired - Fee Related
- 2004-05-12 AU AU2004238364A patent/AU2004238364A1/en not_active Abandoned
- 2004-05-12 EA EA200501800A patent/EA010015B1/ru not_active IP Right Cessation
- 2004-05-12 WO PCT/US2004/014887 patent/WO2004100997A2/en not_active Ceased
- 2004-05-12 CN CNA2004800187597A patent/CN1849141A/zh active Pending
- 2004-05-12 CA CA002525399A patent/CA2525399A1/en not_active Abandoned
- 2004-05-12 MX MXPA05012314A patent/MXPA05012314A/es active IP Right Grant
- 2004-05-12 BR BRPI0411166-4A patent/BRPI0411166A/pt not_active IP Right Cessation
- 2004-05-12 EP EP10160196A patent/EP2204193A3/en not_active Withdrawn
- 2004-05-12 EP EP04760996A patent/EP1628686A2/en not_active Ceased
- 2004-05-12 NZ NZ563042A patent/NZ563042A/en not_active IP Right Cessation
- 2004-05-12 JP JP2006532998A patent/JP2007500218A/ja active Pending
- 2004-05-12 NZ NZ543934A patent/NZ543934A/en not_active IP Right Cessation
- 2004-05-12 KR KR1020057021599A patent/KR101160611B1/ko not_active Expired - Fee Related
-
2005
- 2005-11-10 IL IL171885A patent/IL171885A0/en unknown
- 2005-12-02 IS IS8168A patent/IS8168A/is unknown
- 2005-12-08 ZA ZA200509970A patent/ZA200509970B/en unknown
- 2005-12-09 NO NO20055848A patent/NO20055848L/no not_active Application Discontinuation
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2011
- 2011-04-04 US US13/079,615 patent/US8592365B2/en not_active Expired - Fee Related
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- 2012-04-13 JP JP2012092120A patent/JP2012140466A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP2204193A2 (en) | 2010-07-07 |
| US20070032408A1 (en) | 2007-02-08 |
| WO2004100997A2 (en) | 2004-11-25 |
| CN1849141A (zh) | 2006-10-18 |
| AU2004238364A1 (en) | 2004-11-25 |
| WO2004100997A3 (en) | 2005-05-19 |
| US8592365B2 (en) | 2013-11-26 |
| IS8168A (is) | 2005-12-02 |
| NZ563042A (en) | 2008-09-26 |
| US7919118B2 (en) | 2011-04-05 |
| EA010015B1 (ru) | 2008-06-30 |
| EP2204193A3 (en) | 2010-08-18 |
| ZA200509970B (en) | 2006-11-29 |
| EA200501800A1 (ru) | 2006-08-25 |
| EP1628686A2 (en) | 2006-03-01 |
| KR101160611B1 (ko) | 2012-06-28 |
| US20120115796A1 (en) | 2012-05-10 |
| IL171885A0 (en) | 2006-04-10 |
| BRPI0411166A (pt) | 2006-07-18 |
| KR20060023123A (ko) | 2006-03-13 |
| JP2007500218A (ja) | 2007-01-11 |
| NZ543934A (en) | 2008-06-30 |
| JP2012140466A (ja) | 2012-07-26 |
| MXPA05012314A (es) | 2006-04-18 |
| CA2525399A1 (en) | 2004-11-25 |
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