NO20060177L - Gener som koder for karotenoidforbindelser - Google Patents
Gener som koder for karotenoidforbindelserInfo
- Publication number
- NO20060177L NO20060177L NO20060177A NO20060177A NO20060177L NO 20060177 L NO20060177 L NO 20060177L NO 20060177 A NO20060177 A NO 20060177A NO 20060177 A NO20060177 A NO 20060177A NO 20060177 L NO20060177 L NO 20060177L
- Authority
- NO
- Norway
- Prior art keywords
- cluster
- crty
- crtb
- crte
- crti
- Prior art date
Links
- 235000021466 carotenoid Nutrition 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- -1 carotenoid compounds Chemical class 0.000 title 1
- OINNEUNVOZHBOX-QIRCYJPOSA-K 2-trans,6-trans,10-trans-geranylgeranyl diphosphate(3-) Chemical compound CC(C)=CCC\C(C)=C\CC\C(C)=C\CC\C(C)=C\COP([O-])(=O)OP([O-])([O-])=O OINNEUNVOZHBOX-QIRCYJPOSA-K 0.000 abstract 2
- OINNEUNVOZHBOX-XBQSVVNOSA-N Geranylgeranyl diphosphate Natural products [P@](=O)(OP(=O)(O)O)(OC/C=C(\CC/C=C(\CC/C=C(\CC/C=C(\C)/C)/C)/C)/C)O OINNEUNVOZHBOX-XBQSVVNOSA-N 0.000 abstract 2
- 150000001747 carotenoids Chemical class 0.000 abstract 2
- 108091008053 gene clusters Proteins 0.000 abstract 2
- 239000013598 vector Substances 0.000 abstract 2
- VWFJDQUYCIWHTN-YFVJMOTDSA-N 2-trans,6-trans-farnesyl diphosphate Chemical compound CC(C)=CCC\C(C)=C\CC\C(C)=C\CO[P@](O)(=O)OP(O)(O)=O VWFJDQUYCIWHTN-YFVJMOTDSA-N 0.000 abstract 1
- 101710095468 Cyclase Proteins 0.000 abstract 1
- 108020004414 DNA Proteins 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- VWFJDQUYCIWHTN-UHFFFAOYSA-N Farnesyl pyrophosphate Natural products CC(C)=CCCC(C)=CCCC(C)=CCOP(O)(=O)OP(O)(O)=O VWFJDQUYCIWHTN-UHFFFAOYSA-N 0.000 abstract 1
- 108010065958 Isopentenyl-diphosphate Delta-isomerase Proteins 0.000 abstract 1
- 102000003960 Ligases Human genes 0.000 abstract 1
- 108090000364 Ligases Proteins 0.000 abstract 1
- 108020004511 Recombinant DNA Proteins 0.000 abstract 1
- 230000001851 biosynthetic effect Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 230000002068 genetic effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000008520 organization Effects 0.000 abstract 1
- 108010001545 phytoene dehydrogenase Proteins 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
- C12N15/825—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving pigment biosynthesis
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
- C12N9/0083—Miscellaneous (1.14.99)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/90—Isomerases (5.)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y205/00—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5)
- C12Y205/01—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5) transferring alkyl or aryl groups, other than methyl groups (2.5.1)
- C12Y205/01029—Geranylgeranyl diphosphate synthase (2.5.1.29)
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/30—Fuel from waste, e.g. synthetic alcohol or diesel
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Nutrition Science (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Abstract
En unik karotenoid biosyntetisk genklynge er blitt isolert fra Panteoa agglomerans stamme DC404 hvor den genetiske organiseringen av klyngen er crtE-idi-crtY-crtI-crtB-crtZ. Genene som finnes innen denne klyngen koder for geranylgeranyl pyrofosfat (GGPP) syntetase (CrtE), isopentenylpyrofosfat isomerase (Idi), lysopen syklase (CrtY), fytoen desaturase (CrtI), fotoen syntase (CrtB), og (-karoten hydroksylase (CrtZ). Genklyngen, gener og deres produkter er nyttige for omdannelsen av farnesyl pyrofosfat til karotenoider. Vektorer som inneholder disse DNA-segmenter, vertceller som inneholder vektorene og fremgangsmåter for å produsere de enzymer ved hjelp av rekombinant DNA teknologi i transformerte vertsorganismer blir utgreiet.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47787403P | 2003-06-12 | 2003-06-12 | |
| US52708303P | 2003-12-03 | 2003-12-03 | |
| PCT/US2004/019038 WO2005044975A2 (en) | 2003-06-12 | 2004-06-10 | Genes encoding carotenoid compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20060177L true NO20060177L (no) | 2006-03-10 |
Family
ID=34576491
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20060177A NO20060177L (no) | 2003-06-12 | 2006-01-11 | Gener som koder for karotenoidforbindelser |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6929928B2 (no) |
| EP (1) | EP1631660A2 (no) |
| JP (1) | JP2007516697A (no) |
| CA (1) | CA2528574A1 (no) |
| NO (1) | NO20060177L (no) |
| WO (1) | WO2005044975A2 (no) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6570886B1 (en) | 1997-06-19 | 2003-05-27 | Alcatel | Time slot management method and a main station and substation realizing such a method |
| US20060057726A1 (en) * | 2003-12-03 | 2006-03-16 | Sharpe Pamela L | Method for the positive selection of chromosomal mutations in C1 metabolizing bacteria via homologous recombination |
| US7741070B2 (en) * | 2003-12-24 | 2010-06-22 | Massachusetts Institute Of Technology | Gene targets for enhanced carotenoid production |
| US20060276465A1 (en) * | 2003-12-26 | 2006-12-07 | Eisai R&D Management Co., Ltd. | 1,2-di(cyclic) substituted benzene compounds |
| US7410971B2 (en) * | 2003-12-26 | 2008-08-12 | Eisai R&D Management Co., Ltd. | 1,2-di(cyclic)substituted benzene compounds |
| CN101218352B (zh) * | 2005-03-18 | 2013-09-04 | 米克罗比亚公司 | 产油酵母和真菌中类胡萝卜素的产生 |
| KR100814941B1 (ko) | 2006-02-17 | 2008-03-19 | 주식회사 에이스바이오텍 | 대장균에 의한 라이코펜의 대량 제조방법 |
| US8691555B2 (en) | 2006-09-28 | 2014-04-08 | Dsm Ip Assests B.V. | Production of carotenoids in oleaginous yeast and fungi |
| CN101680015A (zh) | 2007-03-08 | 2010-03-24 | 比奥特伦德生物技术创新工程股份公司 | 通过发酵组成性过产类胡萝卜素的选定菌株或突变体生产高纯度类胡萝卜素的方法 |
| TWI446905B (zh) * | 2007-06-05 | 2014-08-01 | Sanofi Aventis | 經取代之苯甲醯基胺基-氫茚-2-羧酸及相關化合物 |
| WO2009132286A2 (en) * | 2008-04-24 | 2009-10-29 | The City University Of New York | Regulating the production of isoprenoids in algal cells |
| US9113653B2 (en) | 2011-08-19 | 2015-08-25 | Steven J Maranz | Methods of administering probiotic organisms that synthesize carotenoid compounds in situ to enhance human health and nutrition |
| JP6004249B2 (ja) * | 2011-12-28 | 2016-10-05 | 住友ゴム工業株式会社 | イソプレノイドの製造方法、及びイソプレノイド |
| US10059974B2 (en) * | 2012-02-06 | 2018-08-28 | The Research Foundation Of The City University Of New York | Cells and methods for producing lutein |
| US20140123339A1 (en) | 2012-10-31 | 2014-05-01 | Pioneer Hi Bred International Inc | Transformed Plants Having Increased Beta-Carotene Levels, Increased Half-Life and Bioavailability and Methods of Producing Such |
| JP2016010347A (ja) * | 2014-06-27 | 2016-01-21 | 国立大学法人広島大学 | カロテノイド合成酵素およびその利用 |
| WO2017047651A1 (ja) * | 2015-09-18 | 2017-03-23 | 神戸天然物化学株式会社 | 形質転換体、およびテルペノイドの製造方法 |
| JP2019165635A (ja) * | 2016-08-10 | 2019-10-03 | 味の素株式会社 | L−アミノ酸の製造法 |
| CN108728477B (zh) * | 2017-04-24 | 2022-02-22 | 华东理工大学 | 一种高效的转座突变系统及构建方法 |
| US11560583B2 (en) | 2017-06-01 | 2023-01-24 | Knipbio, Inc. | Heterologous carotenoid production in microorganisms |
| WO2019016384A1 (en) * | 2017-07-21 | 2019-01-24 | Dsm Ip Assets B.V. | NEW ENZYME |
| CN107523516B (zh) * | 2017-08-29 | 2020-01-17 | 中国科学院城市环境研究所 | 一株四环素类抗生素降解菌及其应用 |
| US12447202B2 (en) | 2018-05-17 | 2025-10-21 | Lumen Bioscience, Inc. | Arthrospira platensis oral vaccine delivery platform |
| WO2020018586A1 (en) | 2018-07-16 | 2020-01-23 | Lumen Bioscience, Inc. | Thermostable phycobiliproteins produced in spirulina |
| WO2021003456A1 (en) | 2019-07-03 | 2021-01-07 | Lumen Bioscience, Inc. | Arthrospira platensis non-parenteral therapeutic delivery platform |
| CN117264865B (zh) * | 2023-11-21 | 2024-03-12 | 清华大学 | 重组红色红球菌及其在化合物合成中的应用 |
| CN119824017B (zh) * | 2025-01-08 | 2025-12-12 | 昆明理工大学 | 一种支链氨基酸氨基转移酶基因RkBat2及其用途 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5429939A (en) | 1989-04-21 | 1995-07-04 | Kirin Beer Kabushiki Kaisha | DNA sequences useful for the synthesis of carotenoids |
| US5530189A (en) | 1990-03-02 | 1996-06-25 | Amoco Corporation | Lycopene biosynthesis in genetically engineered hosts |
| US5530188A (en) | 1990-03-02 | 1996-06-25 | Amoco Corporation | Beta-carotene biosynthesis in genetically engineered hosts |
| US5545816A (en) | 1990-03-02 | 1996-08-13 | Amoco Corporation | Phytoene biosynthesis in genetically engineered hosts |
| WO1991013078A1 (en) * | 1990-03-02 | 1991-09-05 | Amoco Corporation | Biosynthesis of carotenoids in genetically engineered hosts |
| EP0729175A1 (en) | 1995-02-24 | 1996-08-28 | International Business Machines Corporation | Method for producing deep vertical structures in silicon substrates |
| EP1377598A4 (en) | 2001-01-26 | 2005-08-03 | Cargill Inc | Carotenoid biosynthesis |
| US7252942B2 (en) * | 2002-12-19 | 2007-08-07 | E.I. Du Pont De Nemours And Company | Parallel chromosomal stacking of traits in bacteria |
| US20040219629A1 (en) * | 2002-12-19 | 2004-11-04 | Qiong Cheng | Increasing carotenoid production in bacteria via chromosomal integration |
-
2004
- 2004-03-24 US US10/808,807 patent/US6929928B2/en not_active Expired - Fee Related
- 2004-06-10 CA CA002528574A patent/CA2528574A1/en not_active Abandoned
- 2004-06-10 JP JP2006533795A patent/JP2007516697A/ja not_active Withdrawn
- 2004-06-10 EP EP04816748A patent/EP1631660A2/en not_active Withdrawn
- 2004-06-10 WO PCT/US2004/019038 patent/WO2005044975A2/en not_active Ceased
-
2006
- 2006-01-11 NO NO20060177A patent/NO20060177L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2528574A1 (en) | 2005-05-19 |
| WO2005044975A2 (en) | 2005-05-19 |
| JP2007516697A (ja) | 2007-06-28 |
| US20040253663A1 (en) | 2004-12-16 |
| EP1631660A2 (en) | 2006-03-08 |
| US6929928B2 (en) | 2005-08-16 |
| WO2005044975A3 (en) | 2006-09-08 |
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| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |