NO20060426L - Kannabinoid reseptormodulator - Google Patents

Kannabinoid reseptormodulator

Info

Publication number
NO20060426L
NO20060426L NO20060426A NO20060426A NO20060426L NO 20060426 L NO20060426 L NO 20060426L NO 20060426 A NO20060426 A NO 20060426A NO 20060426 A NO20060426 A NO 20060426A NO 20060426 L NO20060426 L NO 20060426L
Authority
NO
Norway
Prior art keywords
receptor modulator
cannabinoid receptor
prodmg
salt
formula
Prior art date
Application number
NO20060426A
Other languages
English (en)
Other versions
NO335769B1 (no
Inventor
Shigenori Ohkawa
Tetsuya Tsukamoto
Yoshihiro Kiyota
Mika Goto
Shouzou Yamamoto
Masato Shimojou
Masaki Setou
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Publication of NO20060426L publication Critical patent/NO20060426L/no
Publication of NO335769B1 publication Critical patent/NO335769B1/no

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    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/83—Oxygen atoms
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    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
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    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
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    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
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    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
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    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
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    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
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  • Pulmonology (AREA)
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  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Dermatology (AREA)
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  • Ophthalmology & Optometry (AREA)
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  • Biotechnology (AREA)
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  • Obesity (AREA)
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Abstract

Det beskrives en cannabinoidreseptormodulator som inneholder en forbindelse som representeres ved formel (lo) der X er et oksygenatom, osv., R° er en eventuelt substituert acylaminogmppe, ringen A° er en benzenring som videre kan ha en substituent i tillegg til R°, og ringen B er en eventuelt substituert, 5-leddet heterosykel, eller et salt derav eller et prodmg derav.
NO20060426A 2003-06-26 2006-01-26 Kannabinoidreseptormodulator NO335769B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003182039 2003-06-26
PCT/JP2004/009355 WO2005000829A1 (ja) 2003-06-26 2004-06-25 カンナビノイド受容体調節剤

Publications (2)

Publication Number Publication Date
NO20060426L true NO20060426L (no) 2006-02-07
NO335769B1 NO335769B1 (no) 2015-02-09

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Family Applications (1)

Application Number Title Priority Date Filing Date
NO20060426A NO335769B1 (no) 2003-06-26 2006-01-26 Kannabinoidreseptormodulator

Country Status (23)

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US (4) US7465815B2 (no)
EP (1) EP1637527B1 (no)
KR (1) KR101138673B1 (no)
CN (1) CN1816536B (no)
AU (1) AU2004252005B2 (no)
BR (1) BRPI0411740A (no)
CA (1) CA2531020C (no)
CO (1) CO5650243A2 (no)
CR (1) CR8152A (no)
CY (1) CY1114472T1 (no)
DK (1) DK1637527T3 (no)
ES (1) ES2420932T3 (no)
HR (1) HRP20130638T1 (no)
IL (1) IL172577A0 (no)
MX (1) MXPA05013652A (no)
NO (1) NO335769B1 (no)
NZ (1) NZ544298A (no)
PL (1) PL1637527T3 (no)
PT (1) PT1637527E (no)
SI (1) SI1637527T1 (no)
TW (1) TWI329013B (no)
WO (1) WO2005000829A1 (no)
ZA (1) ZA200510304B (no)

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JP5275566B2 (ja) 2003-06-18 2013-08-28 ザ スクリプス リサーチ インスティチュート 反応性非天然アミノ酸遺伝コード付加
BRPI0411740A (pt) * 2003-06-26 2006-05-23 Takeda Pharmaceutical modulador do receptor de canabinóide, composto, pró-droga, droga, método para prevenir ou tratar uma doença ou condição, uso de um composto, e, método para preparar um composto
WO2006066987A1 (en) 2004-12-22 2006-06-29 Ciba Specialty Chemicals Holding Inc. Anti-radical agents
US20080194557A1 (en) * 2007-01-18 2008-08-14 Joseph Barbosa Methods and compositions for the treatment of pain, inflammation and cancer
CN101801187B (zh) * 2007-07-13 2014-07-23 得克萨斯系统大学评议会 大麻素受体的杂环调节剂
US9394267B2 (en) 2007-07-13 2016-07-19 The Cleveland Clinic Foundation Heterocyclic modulators of cannabinoid receptors
US9079854B2 (en) 2007-07-13 2015-07-14 The Cleveland Clinic Foundation Hydrazone modulators of cannabinoid receptors
US8309595B2 (en) * 2007-07-13 2012-11-13 Board Of Regents, The University Of Texas System Hydrazone modulators of cannabinoid receptors
HUE043555T2 (hu) 2007-11-30 2019-09-30 Zynerba Pharmaceuticals Inc Tetrahidrokannabinol gyógyszer elõanyagai (prodrugjai), kompozíciók, amelyek tetrahidrokannabinol gyógyszer elõanyagait tartalmazzák, és eljárások, ezek alkalmazására
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