NO20060426L - Kannabinoid reseptormodulator - Google Patents

Kannabinoid reseptormodulator

Info

Publication number
NO20060426L
NO20060426L NO20060426A NO20060426A NO20060426L NO 20060426 L NO20060426 L NO 20060426L NO 20060426 A NO20060426 A NO 20060426A NO 20060426 A NO20060426 A NO 20060426A NO 20060426 L NO20060426 L NO 20060426L
Authority
NO
Norway
Prior art keywords
receptor modulator
cannabinoid receptor
prodmg
salt
formula
Prior art date
Application number
NO20060426A
Other languages
English (en)
Other versions
NO335769B1 (no
Inventor
Shigenori Ohkawa
Tetsuya Tsukamoto
Yoshihiro Kiyota
Mika Goto
Shouzou Yamamoto
Masato Shimojou
Masaki Setou
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Publication of NO20060426L publication Critical patent/NO20060426L/no
Publication of NO335769B1 publication Critical patent/NO335769B1/no

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    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/83—Oxygen atoms
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    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
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    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
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    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
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    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
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    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
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    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
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  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
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  • Urology & Nephrology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
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Abstract

Det beskrives en cannabinoidreseptormodulator som inneholder en forbindelse som representeres ved formel (lo) der X er et oksygenatom, osv., R° er en eventuelt substituert acylaminogmppe, ringen A° er en benzenring som videre kan ha en substituent i tillegg til R°, og ringen B er en eventuelt substituert, 5-leddet heterosykel, eller et salt derav eller et prodmg derav.
NO20060426A 2003-06-26 2006-01-26 Kannabinoidreseptormodulator NO335769B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003182039 2003-06-26
PCT/JP2004/009355 WO2005000829A1 (ja) 2003-06-26 2004-06-25 カンナビノイド受容体調節剤

Publications (2)

Publication Number Publication Date
NO20060426L true NO20060426L (no) 2006-02-07
NO335769B1 NO335769B1 (no) 2015-02-09

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Family Applications (1)

Application Number Title Priority Date Filing Date
NO20060426A NO335769B1 (no) 2003-06-26 2006-01-26 Kannabinoidreseptormodulator

Country Status (23)

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US (4) US7465815B2 (no)
EP (1) EP1637527B1 (no)
KR (1) KR101138673B1 (no)
CN (1) CN1816536B (no)
AU (1) AU2004252005B2 (no)
BR (1) BRPI0411740A (no)
CA (1) CA2531020C (no)
CO (1) CO5650243A2 (no)
CR (1) CR8152A (no)
CY (1) CY1114472T1 (no)
DK (1) DK1637527T3 (no)
ES (1) ES2420932T3 (no)
HR (1) HRP20130638T1 (no)
IL (1) IL172577A0 (no)
MX (1) MXPA05013652A (no)
NO (1) NO335769B1 (no)
NZ (1) NZ544298A (no)
PL (1) PL1637527T3 (no)
PT (1) PT1637527E (no)
SI (1) SI1637527T1 (no)
TW (1) TWI329013B (no)
WO (1) WO2005000829A1 (no)
ZA (1) ZA200510304B (no)

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BRPI0411475A (pt) * 2003-06-18 2006-07-25 Scripps Research Inst adições de código genético de aminoácido reativo não natural
US7465815B2 (en) * 2003-06-26 2008-12-16 Takeda Pharmaceutical Company Limited Cannabinoid receptor modulator
US20080305055A1 (en) 2004-12-22 2008-12-11 Werner Baschong Anti-Radical Agents
WO2008089307A2 (en) * 2007-01-18 2008-07-24 Lexicon Pharmaceuticals, Inc. Delta 5 desaturase inhibitors for the treatment of pain, inflammation and cancer
JP5453258B2 (ja) * 2007-07-13 2014-03-26 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム カンナビノイド受容体の複素環式モジュレーター
US9394267B2 (en) 2007-07-13 2016-07-19 The Cleveland Clinic Foundation Heterocyclic modulators of cannabinoid receptors
US8309595B2 (en) * 2007-07-13 2012-11-13 Board Of Regents, The University Of Texas System Hydrazone modulators of cannabinoid receptors
US9079854B2 (en) 2007-07-13 2015-07-14 The Cleveland Clinic Foundation Hydrazone modulators of cannabinoid receptors
JP5551604B2 (ja) 2007-11-30 2014-07-16 オールトランツ インコーポレイティド テトラヒドロカンナビノールのプロドラッグ、テトラヒドロカンナビノールのプロドラッグを含む組成物、及び同一のものを使用する方法
WO2010104194A1 (en) 2009-03-10 2010-09-16 Takeda Pharmaceutical Company Limited Benzofuran derivatives
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