NO20060763L - Metode for asymmetrisk aydrogenering av Beta-Aminoketoner - Google Patents

Metode for asymmetrisk aydrogenering av Beta-Aminoketoner

Info

Publication number
NO20060763L
NO20060763L NO20060763A NO20060763A NO20060763L NO 20060763 L NO20060763 L NO 20060763L NO 20060763 A NO20060763 A NO 20060763A NO 20060763 A NO20060763 A NO 20060763A NO 20060763 L NO20060763 L NO 20060763L
Authority
NO
Norway
Prior art keywords
aminoketones
beta
asymmetric hydrogenation
monosubstituted
enantiomers
Prior art date
Application number
NO20060763A
Other languages
English (en)
Inventor
Hans-Petter Mettler
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Publication of NO20060763L publication Critical patent/NO20060763L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40—Radicals substituted by oxygen atoms
    • C07D307/42—Singly bound oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Furan Compounds (AREA)

Abstract

Oppfinnelsen angår en fremgangsmåte for fremstilling av enantiomert anrikede eller enantiomert rene (S)- eller (R)-N-monosubstituerte p-aminoalkoholer med formel I og enantiomerer og deres addisjonssalter av protonsyrer, X representer S eller O og R representerer C1-6-alkyl, C3-8-cykloalkyl, aryl eller aralkyl.
NO20060763A 2003-09-01 2006-02-17 Metode for asymmetrisk aydrogenering av Beta-Aminoketoner NO20060763L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03077734A EP1510517A1 (en) 2003-09-01 2003-09-01 Process for the asymmetric hydrogenation of beta-amino ketones
PCT/EP2004/009690 WO2005021527A2 (en) 2003-09-01 2004-08-31 Process for the asymmetric hydrogenation of beta-amino ketones

Publications (1)

Publication Number Publication Date
NO20060763L true NO20060763L (no) 2006-03-17

Family

ID=34089676

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20060763A NO20060763L (no) 2003-09-01 2006-02-17 Metode for asymmetrisk aydrogenering av Beta-Aminoketoner

Country Status (11)

Country Link
US (1) US20060252945A1 (no)
EP (2) EP1510517A1 (no)
JP (1) JP2007504192A (no)
KR (1) KR20060123066A (no)
CN (1) CN1842523A (no)
AU (1) AU2004268057A1 (no)
EA (1) EA200600502A1 (no)
IL (1) IL173577A0 (no)
NO (1) NO20060763L (no)
SG (1) SG144912A1 (no)
WO (1) WO2005021527A2 (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1539673T3 (da) * 2002-07-09 2008-01-21 Lonza Ag Fremgangsmåde til fremstilling af N-monosubstituerede beta-aminoalkoholer
EP2044049A2 (en) 2006-07-03 2009-04-08 Ranbaxy Laboratories Limited Process for the preparation of enantiomerically pure salts of n-methyl- 3 -( 1-naph-thaleneoxy)- 3 - (-2-thienyl) propanamine
SI22839A (sl) * 2008-07-07 2010-01-29 Krka, Tovarna Zdravil, D.D. Sinteza duloksetina in njegovih farmacevtsko sprejemljivih soli z uporabo postopka asimetriäśnega transfer hidrogeniranja
EP2329013B1 (en) 2008-08-27 2015-10-28 Codexis, Inc. Ketoreductase polypeptides for the production of a 3-aryl-3-hydroxypropanamine from a 3-aryl-3-ketopropanamine
WO2010025287A2 (en) 2008-08-27 2010-03-04 Codexis, Inc. Ketoreductase polypeptides for the production of 3-aryl-3-hydroxypropanamine from a 3-aryl-3-ketopropanamine
WO2011128370A1 (en) 2010-04-13 2011-10-20 Krka, D.D., Novo Mesto Synthesis of duloxetine and/or pharmaceutically acceptable salts thereof
PL2426116T3 (pl) 2010-08-30 2013-11-29 Saltigo Gmbh Sposób wytwarzania (S)-3-N-metyloamino-1-(2-tienylo)-1-propanolu
CN104056663B (zh) * 2013-03-22 2016-12-28 上海交通大学 一种面手性双反应中心钌催化剂及其合成与应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10036516A1 (de) * 2000-07-27 2002-02-07 Asta Medica Ag Verfahren zur Herstellung von enantiomerenreinen 6,8-Dihydroxyoctansäureestern durch assymetrische katalytische Hydrierung
WO2003062219A1 (en) * 2002-01-24 2003-07-31 Eli Lilly And Company Process for preparing an intermediate useful for the asymmetric synthesis of duloxetine
WO2003061825A1 (en) * 2002-01-24 2003-07-31 Dsm Ip Assets B.V. Process for preparing nonracemic chiral alcohols
WO2003061826A1 (en) * 2002-01-24 2003-07-31 Dsm Ip Assets B.V. Process for preparing nonracemic chiral alcohols

Also Published As

Publication number Publication date
JP2007504192A (ja) 2007-03-01
CN1842523A (zh) 2006-10-04
WO2005021527A3 (en) 2005-07-14
WO2005021527A2 (en) 2005-03-10
IL173577A0 (en) 2006-07-05
EA200600502A1 (ru) 2006-08-25
EP1664014A2 (en) 2006-06-07
EP1510517A1 (en) 2005-03-02
SG144912A1 (en) 2008-08-28
KR20060123066A (ko) 2006-12-01
AU2004268057A1 (en) 2005-03-10
US20060252945A1 (en) 2006-11-09

Similar Documents

Publication Publication Date Title
SG170729A1 (en) Processes and intermediates for preparing steric compounds
AR036187A1 (es) Un proceso para la preparacion de perindopril, compuestos analogos y sus sales, compuesto intermediario 2,5-dioxo-oxazolidina y proceso para preparar un intermediario
AR063988A1 (es) Derivados heterociclicos, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen
CO6362007A2 (es) Derivados de azaspiranil-alquilcarbamatos de heterociclos de 5 eslabones, su preparación y su aplicación en terapeútica
NO20060763L (no) Metode for asymmetrisk aydrogenering av Beta-Aminoketoner
NO20050134L (no) Difenylazetidioner substituert med syregrupper, fremgangsmate for fremstilling av disse, medikamenter inneholdende disse forbindelser og deres anvendelse
AR044177A1 (es) Proceso para la preparacion de trans-isomeros de derivados de la difenilazetidinona
EA201170094A1 (ru) Производные замещенного пиримидо[2,1-а]изохинолин-4-она
NO20064160L (no) Nye azaibicykliske forbindelser, fremgangsmate for deres fremstilling og farmasoytiske sammensetninger inneholdende dem
DE502006009032D1 (de) Verfahren zur herstellung von glycerincarbonat
GT200300095A (es) Derivados de isoquinolina
DE602006021411D1 (de) Verfahren zur herstellung von optional 2-substituierten 1,6-dihydro-6-oxo-4-pyrimidincarboxylsäuren
WO2014003203A3 (en) Method for producing stereoselective epoxyketone compound
ATE261953T1 (de) Verfahren zur herstellung von citalopram
DE60309251D1 (de) Verfahren zur Herstellung von Donepezil
ATE239701T1 (de) Polyethoxylierte retinamid-derivate und verfahren zu ihrer herstellung
BR0312586A (pt) Derivados de pirolidina como antagonistas e oxitocina
CY1112979T1 (el) Διαδικασια για την παρασκευη της ενωσης (s)-1-αλκυλ-2',6'-πιπεκολοξυλιδιδιου
ATE489352T1 (de) Verfahren zur herstellung von brenztraubensäure
ATE489367T1 (de) Verfahren und zwischenprodukt zur herstellung von donezepil
CO6331466A2 (es) Derivados de 1-bencil-cinolin-4-(1h)-ona sustituidos, su preparacion y su aplicacion en terapeutica
AR077492A1 (es) Derivados cromenicos utiles para el tratamiento de enfermedades psiquiatricas y neurologicas, procedimiento para prepararlos y composiciones farmaceuticas que los comprenden.
NO330989B1 (no) Nye piperazinderivater, fremgangsmater for fremstilling av slike og deres anvendelse som syntesemellomprodukter.
WO2009016812A1 (ja) ２－フェニルキノリン－４－カルボン酸誘導体を有効成分とする貧血の予防及び／又は治療剤
DE602005013007D1 (de) Verfahren zur herstellung von lactonen

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application